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The map label for this gene is ftsK [H]

Identifier: 167040268

GI number: 167040268

Start: 1648597

End: 1650723

Strand: Reverse

Name: ftsK [H]

Synonym: Teth514_1631

Alternate gene names: 167040268

Gene position: 1650723-1648597 (Counterclockwise)

Preceding gene: 167040269

Following gene: 167040267

Centisome position: 67.18

GC content: 32.82

Gene sequence:

>2127_bases
ATGATTGATAAAAAACAAAAGTCTCTCAAAAACGAAATCATTGGAATTATATTTTTGGCTTTTACACTTATTTCTTTTTT
AAGCCTTTATACAGATACAACTGGTGCTATAGGTAAAAACATAGGAATTTTTTTAAAGGGTTCTTTTGGGATAGGTTCTT
ATGTTGTATCTGCTTTACTTTTAGTATTTGCGTTGATGTTTCTTTTTAATAATCGAGATTTTATAAAATTACATAAAGCT
GCAGCACTTTTTGGACTTTTTCTAACCCTCATAAGTTTAGATCATTTGTATTATTTCCCTTCTAATGAAGGATTAAAAAA
TTATATTTTAGCTGCTTACACTAATGGTATAAACAATATGGGTGGAGGAGTTGTTGCTGCCTTACTGGTATATTTTCTAG
TAAAACTTTTGGGTATCACAGGAAGCTATATATTATTGTTTTCTTCTTTGGCAATTTTTATAGTGCTTATTACAAATGTA
TCTATCGTAAACCTGATGGAATCTTCCTATCAGAAGTTTAAACAACGTAAAAAAAAGTCAAAAAAAACAGACCATGAGAA
GGAAGTAATTTCTACCTCTACTTCTCAGGAGGATTTCACACCTTTAATTGAAGAAAATATAACAGATAAAAATAGAACAA
TCGATATAATTGAACAAGTAGAAGAAGAAAGAAAAATCTATGAAAAAGGTACAAAAGATAAAGAAGAGGTTATAGAAAGC
GAGTATCTTCCTCCTCCTATAACCCTTTTAAAAGAGGCAATTCCCCCACCAAAAATAAAAAATGAAGTGTTAATGGAGAA
AGTAAAAAAAATAGAAGACACCCTTAAAAACTTCGGAGTTGATGCAAAAGTTATCCAAGTGACAAAGGGGCCTGCAATTA
CTCGTTTTGAATTGCAACCTAGTGCAGGAGTCAAAGTTAGCAGAATTGTGAGTTTAACAGATGACATTGCTTTAAGTCTA
GCTGCGCCTTCTGTGAGAATAGAAGCGCCGATTCCTGGTAAATCTGCTATTGGAATAGAAGTCCCAAATGATAAAATAGC
TCCAGTATATTTGAGAGAAGTAATAGATAGCAAAAAGTTTAGAAATTTTAAATCAGACTTAGCAATTGGTTTAGGAAAGG
ATATCGCAGGTAATATTGTCATAGTAGATTTGTCTAAAATGCCTCATTTGCTCATTGCAGGTGCAACAGGTTCTGGTAAA
AGTGTTTGCATAAATTCTCTTATAGTGAGTTTGTTATACAAAGCCTCTCCACAACAGGTGAAAATGATATTGATAGATCC
AAAAGTAGTAGAACTTAATATTTATAACGGCATTCCTCATCTCTTAACTCCGGTTGTCACAGACCCTAAAAAGGCAGCCG
GTGTCTTAAATTGGGCAGTACAAGAAATGACTAAGCGTTATAATTTATTTGCCCAATATGGAGTTAGAGATATAGACAGC
TATAACGAAAAATACAAAGAAAACAGCTTATATAAAATTGTAATCATAATTGATGAGCTTTCTGACTTAATGATGGTCTC
TCCTGCAGAAGTAGAAGAATATATATTTAGGTTAGCTCAAATGGCAAGAGCAGCTGGCATTCATTTGGTCATTGCTACCC
AAAGACCCTCTGTTGATGTAATAACGGGAGTTATTAAAGCTAATATTCCTTCAAGGATTTCTTTTGCTGTATCTTCTCAA
ATTGACTCAAGAACAATTTTGGATATGGCAGGTGCAGAAAAACTTTTAGGAAAAGGCGATATGCTTTTTAACCCTATAGG
AGCAGCAAAACCTATGCGAATTCAAGGAGCTTTTATCTCTGAAGAAGAAGTAGAAGCTGTAGTAAATTTCTTAAAAAATC
ATTCTAAGCCTCAGTACGAAGAAATAGAAATTGAGGGAAAGACAAATGGAAAAATTTTTGAACAACAAGAGGATGAGTTA
TTAGAAGATGCTATTTCTGTAATTTTAGAAACAGGGCAAGCTTCTATTTCAATGTTACAAAGAAGATTAAGAATTGGGTA
CGCGAGAGCTGCCCGAATTATAGATCAATTAGAGCAAAAAGGTATTATAAGCGGTTATGATGGTTCTAAGCCAAGGCAAA
TTCTTGTATCAAAAGAAGAAATAAAAAAAATATTAGAAGAATCTTAA

Upstream 100 bases:

>100_bases
ATAGATGTGTTTAAAAAATTAGCACATCTATTTTTTTGTTGCTATTTTACATAATTAATACTAAAATTTTTATAGAAGAA
ATTATAAACAGGTGGTATAT

Downstream 100 bases:

>100_bases
AATAGAAAGGAAATGCAGATGAAAAATGTAGGAATTATATCTCTTGGATGTCACAAAAACACAATTGATTCAGAAAAAAT
GTTAGCAATTTTAAAAGAAA

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MIDKKQKSLKNEIIGIIFLAFTLISFLSLYTDTTGAIGKNIGIFLKGSFGIGSYVVSALLLVFALMFLFNNRDFIKLHKA
AALFGLFLTLISLDHLYYFPSNEGLKNYILAAYTNGINNMGGGVVAALLVYFLVKLLGITGSYILLFSSLAIFIVLITNV
SIVNLMESSYQKFKQRKKKSKKTDHEKEVISTSTSQEDFTPLIEENITDKNRTIDIIEQVEEERKIYEKGTKDKEEVIES
EYLPPPITLLKEAIPPPKIKNEVLMEKVKKIEDTLKNFGVDAKVIQVTKGPAITRFELQPSAGVKVSRIVSLTDDIALSL
AAPSVRIEAPIPGKSAIGIEVPNDKIAPVYLREVIDSKKFRNFKSDLAIGLGKDIAGNIVIVDLSKMPHLLIAGATGSGK
SVCINSLIVSLLYKASPQQVKMILIDPKVVELNIYNGIPHLLTPVVTDPKKAAGVLNWAVQEMTKRYNLFAQYGVRDIDS
YNEKYKENSLYKIVIIIDELSDLMMVSPAEVEEYIFRLAQMARAAGIHLVIATQRPSVDVITGVIKANIPSRISFAVSSQ
IDSRTILDMAGAEKLLGKGDMLFNPIGAAKPMRIQGAFISEEEVEAVVNFLKNHSKPQYEEIEIEGKTNGKIFEQQEDEL
LEDAISVILETGQASISMLQRRLRIGYARAARIIDQLEQKGIISGYDGSKPRQILVSKEEIKKILEES

Sequences:

>Translated_708_residues
MIDKKQKSLKNEIIGIIFLAFTLISFLSLYTDTTGAIGKNIGIFLKGSFGIGSYVVSALLLVFALMFLFNNRDFIKLHKA
AALFGLFLTLISLDHLYYFPSNEGLKNYILAAYTNGINNMGGGVVAALLVYFLVKLLGITGSYILLFSSLAIFIVLITNV
SIVNLMESSYQKFKQRKKKSKKTDHEKEVISTSTSQEDFTPLIEENITDKNRTIDIIEQVEEERKIYEKGTKDKEEVIES
EYLPPPITLLKEAIPPPKIKNEVLMEKVKKIEDTLKNFGVDAKVIQVTKGPAITRFELQPSAGVKVSRIVSLTDDIALSL
AAPSVRIEAPIPGKSAIGIEVPNDKIAPVYLREVIDSKKFRNFKSDLAIGLGKDIAGNIVIVDLSKMPHLLIAGATGSGK
SVCINSLIVSLLYKASPQQVKMILIDPKVVELNIYNGIPHLLTPVVTDPKKAAGVLNWAVQEMTKRYNLFAQYGVRDIDS
YNEKYKENSLYKIVIIIDELSDLMMVSPAEVEEYIFRLAQMARAAGIHLVIATQRPSVDVITGVIKANIPSRISFAVSSQ
IDSRTILDMAGAEKLLGKGDMLFNPIGAAKPMRIQGAFISEEEVEAVVNFLKNHSKPQYEEIEIEGKTNGKIFEQQEDEL
LEDAISVILETGQASISMLQRRLRIGYARAARIIDQLEQKGIISGYDGSKPRQILVSKEEIKKILEES
>Mature_708_residues
MIDKKQKSLKNEIIGIIFLAFTLISFLSLYTDTTGAIGKNIGIFLKGSFGIGSYVVSALLLVFALMFLFNNRDFIKLHKA
AALFGLFLTLISLDHLYYFPSNEGLKNYILAAYTNGINNMGGGVVAALLVYFLVKLLGITGSYILLFSSLAIFIVLITNV
SIVNLMESSYQKFKQRKKKSKKTDHEKEVISTSTSQEDFTPLIEENITDKNRTIDIIEQVEEERKIYEKGTKDKEEVIES
EYLPPPITLLKEAIPPPKIKNEVLMEKVKKIEDTLKNFGVDAKVIQVTKGPAITRFELQPSAGVKVSRIVSLTDDIALSL
AAPSVRIEAPIPGKSAIGIEVPNDKIAPVYLREVIDSKKFRNFKSDLAIGLGKDIAGNIVIVDLSKMPHLLIAGATGSGK
SVCINSLIVSLLYKASPQQVKMILIDPKVVELNIYNGIPHLLTPVVTDPKKAAGVLNWAVQEMTKRYNLFAQYGVRDIDS
YNEKYKENSLYKIVIIIDELSDLMMVSPAEVEEYIFRLAQMARAAGIHLVIATQRPSVDVITGVIKANIPSRISFAVSSQ
IDSRTILDMAGAEKLLGKGDMLFNPIGAAKPMRIQGAFISEEEVEAVVNFLKNHSKPQYEEIEIEGKTNGKIFEQQEDEL
LEDAISVILETGQASISMLQRRLRIGYARAARIIDQLEQKGIISGYDGSKPRQILVSKEEIKKILEES

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=482, Percent_Identity=49.3775933609959, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 78511; Mature: 78511

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKKQKSLKNEIIGIIFLAFTLISFLSLYTDTTGAIGKNIGIFLKGSFGIGSYVVSALL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
LVFALMFLFNNRDFIKLHKAAALFGLFLTLISLDHLYYFPSNEGLKNYILAAYTNGINNM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCC
GGGVVAALLVYFLVKLLGITGSYILLFSSLAIFIVLITNVSIVNLMESSYQKFKQRKKKS
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKTDHEKEVISTSTSQEDFTPLIEENITDKNRTIDIIEQVEEERKIYEKGTKDKEEVIES
CCCCHHHHHHHCCCCCHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
EYLPPPITLLKEAIPPPKIKNEVLMEKVKKIEDTLKNFGVDAKVIQVTKGPAITRFELQP
CCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECC
SAGVKVSRIVSLTDDIALSLAAPSVRIEAPIPGKSAIGIEVPNDKIAPVYLREVIDSKKF
CCCCCHHHHHHHHHHHHHEEECCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
RNFKSDLAIGLGKDIAGNIVIVDLSKMPHLLIAGATGSGKSVCINSLIVSLLYKASPQQV
HHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCE
KMILIDPKVVELNIYNGIPHLLTPVVTDPKKAAGVLNWAVQEMTKRYNLFAQYGVRDIDS
EEEEECCEEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
YNEKYKENSLYKIVIIIDELSDLMMVSPAEVEEYIFRLAQMARAAGIHLVIATQRPSVDV
HHHHHHCCCEEEEEEEEECHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHH
ITGVIKANIPSRISFAVSSQIDSRTILDMAGAEKLLGKGDMLFNPIGAAKPMRIQGAFIS
HHHHHHCCCCCCEEHHHHCCCCCHHHHHHHCHHHHHCCCCCEECCCCCCCCEEEEECCCC
EEEVEAVVNFLKNHSKPQYEEIEIEGKTNGKIFEQQEDELLEDAISVILETGQASISMLQ
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
RRLRIGYARAARIIDQLEQKGIISGYDGSKPRQILVSKEEIKKILEES
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEECCHHHHHHHHHCC
>Mature Secondary Structure
MIDKKQKSLKNEIIGIIFLAFTLISFLSLYTDTTGAIGKNIGIFLKGSFGIGSYVVSALL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
LVFALMFLFNNRDFIKLHKAAALFGLFLTLISLDHLYYFPSNEGLKNYILAAYTNGINNM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCC
GGGVVAALLVYFLVKLLGITGSYILLFSSLAIFIVLITNVSIVNLMESSYQKFKQRKKKS
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKTDHEKEVISTSTSQEDFTPLIEENITDKNRTIDIIEQVEEERKIYEKGTKDKEEVIES
CCCCHHHHHHHCCCCCHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
EYLPPPITLLKEAIPPPKIKNEVLMEKVKKIEDTLKNFGVDAKVIQVTKGPAITRFELQP
CCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECC
SAGVKVSRIVSLTDDIALSLAAPSVRIEAPIPGKSAIGIEVPNDKIAPVYLREVIDSKKF
CCCCCHHHHHHHHHHHHHEEECCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
RNFKSDLAIGLGKDIAGNIVIVDLSKMPHLLIAGATGSGKSVCINSLIVSLLYKASPQQV
HHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCE
KMILIDPKVVELNIYNGIPHLLTPVVTDPKKAAGVLNWAVQEMTKRYNLFAQYGVRDIDS
EEEEECCEEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
YNEKYKENSLYKIVIIIDELSDLMMVSPAEVEEYIFRLAQMARAAGIHLVIATQRPSVDV
HHHHHHCCCEEEEEEEEECHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHH
ITGVIKANIPSRISFAVSSQIDSRTILDMAGAEKLLGKGDMLFNPIGAAKPMRIQGAFIS
HHHHHHCCCCCCEEHHHHCCCCCHHHHHHHCHHHHHCCCCCEECCCCCCCCEEEEECCCC
EEEVEAVVNFLKNHSKPQYEEIEIEGKTNGKIFEQQEDELLEDAISVILETGQASISMLQ
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
RRLRIGYARAARIIDQLEQKGIISGYDGSKPRQILVSKEEIKKILEES
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]