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The map label for this gene is moaC [H]

Identifier: 167040033

GI number: 167040033

Start: 1434455

End: 1434931

Strand: Direct

Name: moaC [H]

Synonym: Teth514_1393

Alternate gene names: 167040033

Gene position: 1434455-1434931 (Clockwise)

Preceding gene: 167040032

Following gene: 167040034

Centisome position: 58.38

GC content: 35.85

Gene sequence:

>477_bases
ATGAATTTAACACACATTAATGAAGAAGGTAGAGCAAGAATGGTCGATGTTAGCGATAAAGATGAGACAAAAAGGGAAGC
TGTTGCAATAGGAAGCATTTATATGAAAAGTGAAACTTTAAGAAGAATACATGAAGGAACTATTAAAAAAGGAGATGTCC
TAGCAGTTGCACAGGTTGCTGGTATTATGGCTGCGAAAAATACATCTCATATGATTCCAATGTGTCATCCTATCATGATA
ACCGGGTGTGATATTAGTTTTAGTTTGGATTTTGAAAATTCAAAGATTGACATTAAAGCGGTAGTTAAAACTGTTGGACA
AACAGGGGTTGAGATGGAGGCATTGACTGCAGTTACGGTTGCAGCTCTTACGATTTATGATATGTGTAAAGCAATAGATA
GAGACATGGTTATAAGCGAAATAATGCTTGTGAAAAAAAGTGGTGGAAAATCAGGCCTTTATGAAAGGGAGGTTTAA

Upstream 100 bases:

>100_bases
AATGCTGGAACATGCAATCTTAAGTAAGCCGGCAGGGCATAATCTTGAAAAGGAAATAAGCCAGAATCAAAAAATGATGT
TTCAAATAGGAGGATAGTAT

Downstream 100 bases:

>100_bases
TAATGGCAAAGGTGGTGTCAGTTAATATTAGCGAAAAGAAAGGAACTGTAAAAAAGCCTATAGAAAAGGGATATTTTAGA
GAAAACCACGGGCTTGAAGG

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MNLTHINEEGRARMVDVSDKDETKREAVAIGSIYMKSETLRRIHEGTIKKGDVLAVAQVAGIMAAKNTSHMIPMCHPIMI
TGCDISFSLDFENSKIDIKAVVKTVGQTGVEMEALTAVTVAALTIYDMCKAIDRDMVISEIMLVKKSGGKSGLYEREV

Sequences:

>Translated_158_residues
MNLTHINEEGRARMVDVSDKDETKREAVAIGSIYMKSETLRRIHEGTIKKGDVLAVAQVAGIMAAKNTSHMIPMCHPIMI
TGCDISFSLDFENSKIDIKAVVKTVGQTGVEMEALTAVTVAALTIYDMCKAIDRDMVISEIMLVKKSGGKSGLYEREV
>Mature_158_residues
MNLTHINEEGRARMVDVSDKDETKREAVAIGSIYMKSETLRRIHEGTIKKGDVLAVAQVAGIMAAKNTSHMIPMCHPIMI
TGCDISFSLDFENSKIDIKAVVKTVGQTGVEMEALTAVTVAALTIYDMCKAIDRDMVISEIMLVKKSGGKSGLYEREV

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=53.2051282051282, Blast_Score=167, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=53.0201342281879, Blast_Score=163, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=46.4516129032258, Blast_Score=142, Evalue=7e-35,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=46.5277777777778, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17278; Mature: 17278

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTHINEEGRARMVDVSDKDETKREAVAIGSIYMKSETLRRIHEGTIKKGDVLAVAQVA
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCEEHHHHHH
GIMAAKNTSHMIPMCHPIMITGCDISFSLDFENSKIDIKAVVKTVGQTGVEMEALTAVTV
HHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
AALTIYDMCKAIDRDMVISEIMLVKKSGGKSGLYEREV
HHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLTHINEEGRARMVDVSDKDETKREAVAIGSIYMKSETLRRIHEGTIKKGDVLAVAQVA
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCEEHHHHHH
GIMAAKNTSHMIPMCHPIMITGCDISFSLDFENSKIDIKAVVKTVGQTGVEMEALTAVTV
HHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
AALTIYDMCKAIDRDMVISEIMLVKKSGGKSGLYEREV
HHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA