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The map label for this gene is yqeV [H]

Identifier: 167039974

GI number: 167039974

Start: 1371300

End: 1372649

Strand: Direct

Name: yqeV [H]

Synonym: Teth514_1333

Alternate gene names: 167039974

Gene position: 1371300-1372649 (Clockwise)

Preceding gene: 167039973

Following gene: 167039975

Centisome position: 55.81

GC content: 33.85

Gene sequence:

>1350_bases
GTGACAAGAGTAGATTTATCTCTTAAAAGAAATGGTCATAAAAAAGCTGTGGCTTTTTACACTTTAGGCTGTAAGGTAAA
TCAATATGAGACAGAAGTCATGGCTGAGCTTTTTAAAAAAGCTGGTTATGAAGTAGTTGATTTTGACGAAAAAGCGGATG
TTTATGTAATAAACACTTGTACTGTAACAAATAGAAGTGATATGAAGTCAAGGCAGGAGATACGAAAAGCTAGAAAGAAA
AATCCTGATGCGCTGGTAGTAGCTGTTGGCTGCTATGTGCAAGTAAGTCCAGAGGAAGCTTTTTCTCTTCCGGAAGTGGA
CATAGCGATTGGTACGAAAAATAAGGACAAAATAGTGGAATTAGTAGAGGAATTTACACAAAAAAATCAAAAGTTGAGTG
TGGTAAATAATATAATGACTCAAAAGGAATATGAGGAATTTGGAGTAACAGCTTATACAGAAAGGACAAGGGCATATATA
AAGATTCAAGACGGCTGCAATCAATACTGTACTTACTGCATAATCCCTTACGCCAGGGGACCTGTGAGAAGTAGAGACCC
CAAAAAAGTACTAGATGAAGTAAAAAGGTTTGCTGATTCAGGGTATAAAGAAATTGTTCTCACAGGTATACACATAGCTT
CCTATGGCAAAGATTTAAAAAATATTGGGCTTTTGGACATTATAAAGATGATTCATGAAATAGATGGCATAAAAAGGATA
AGACTTAGTTCTATTGAGCCTACTTTTTTAACTGAAGAGTTTGTGAAAGAAATAGCTAACTTGCCTAAGATGTGCAGGCA
TTATCATGTATCCCTTCAAAGTGGATGTGATGAAACCTTAAAAAGAATGGGAAGAAGATATACTACAAAGGAGTACAAAA
GTGTAATTGATAGGTTAAGAGAATACATCAAGGATGTGGCGATAACTACAGATGTTATGGTGGGATTTCCTGGTGAAACG
GAAGAGGAGTTTCTCAAGACTTACAAATTTGTGGAAGAGATTTGTTTTAGCAAAATGCATGTTTTTAAATATTCAAGGAG
AAAAGGTACAAGAGCATACAACTTTCCAAATCAAGTTGCAAATCATATAAAAGAAGATAGGAGTAAAAAGCTCATAGAAT
TGTCTAATAGGTGTGAATATAAATTTATGGAGAGTTTTATAGGGAAAACTTTGGAAGTCCTCTTTGAACAACCAGTAAAG
AATATGGAGGGTTATGTAGAAGGCTTGACTGATAATTATTTAAGTATAGCTGTTAAAGGGGATATAAAGTTACTTAGAAA
TGAGATTTTTCCAGTGAAAATAAAAGAAATAAAAGATAATTTCTTAATTGGAGAAATTGAAGGAATTTAA

Upstream 100 bases:

>100_bases
TTCCAACGCCAACGGCTTCCAGAAAAAATAAAAGTTCCTGAAAGTGCTTTTTATGTGATATAATATGAAGAAAAGATTTA
ATAGGAGGAGCACTTAAAAA

Downstream 100 bases:

>100_bases
CCTGATGTGTAGAATATAAAAAGAGGAGGTGAAAGGATGTCAGATTGCATTTTTTGTAAAATTATAAATAAAGAAGTACC
TTCCAATATAGTCTATGAAG

Product: MiaB-like tRNA modifying protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTRVDLSLKRNGHKKAVAFYTLGCKVNQYETEVMAELFKKAGYEVVDFDEKADVYVINTCTVTNRSDMKSRQEIRKARKK
NPDALVVAVGCYVQVSPEEAFSLPEVDIAIGTKNKDKIVELVEEFTQKNQKLSVVNNIMTQKEYEEFGVTAYTERTRAYI
KIQDGCNQYCTYCIIPYARGPVRSRDPKKVLDEVKRFADSGYKEIVLTGIHIASYGKDLKNIGLLDIIKMIHEIDGIKRI
RLSSIEPTFLTEEFVKEIANLPKMCRHYHVSLQSGCDETLKRMGRRYTTKEYKSVIDRLREYIKDVAITTDVMVGFPGET
EEEFLKTYKFVEEICFSKMHVFKYSRRKGTRAYNFPNQVANHIKEDRSKKLIELSNRCEYKFMESFIGKTLEVLFEQPVK
NMEGYVEGLTDNYLSIAVKGDIKLLRNEIFPVKIKEIKDNFLIGEIEGI

Sequences:

>Translated_449_residues
MTRVDLSLKRNGHKKAVAFYTLGCKVNQYETEVMAELFKKAGYEVVDFDEKADVYVINTCTVTNRSDMKSRQEIRKARKK
NPDALVVAVGCYVQVSPEEAFSLPEVDIAIGTKNKDKIVELVEEFTQKNQKLSVVNNIMTQKEYEEFGVTAYTERTRAYI
KIQDGCNQYCTYCIIPYARGPVRSRDPKKVLDEVKRFADSGYKEIVLTGIHIASYGKDLKNIGLLDIIKMIHEIDGIKRI
RLSSIEPTFLTEEFVKEIANLPKMCRHYHVSLQSGCDETLKRMGRRYTTKEYKSVIDRLREYIKDVAITTDVMVGFPGET
EEEFLKTYKFVEEICFSKMHVFKYSRRKGTRAYNFPNQVANHIKEDRSKKLIELSNRCEYKFMESFIGKTLEVLFEQPVK
NMEGYVEGLTDNYLSIAVKGDIKLLRNEIFPVKIKEIKDNFLIGEIEGI
>Mature_448_residues
TRVDLSLKRNGHKKAVAFYTLGCKVNQYETEVMAELFKKAGYEVVDFDEKADVYVINTCTVTNRSDMKSRQEIRKARKKN
PDALVVAVGCYVQVSPEEAFSLPEVDIAIGTKNKDKIVELVEEFTQKNQKLSVVNNIMTQKEYEEFGVTAYTERTRAYIK
IQDGCNQYCTYCIIPYARGPVRSRDPKKVLDEVKRFADSGYKEIVLTGIHIASYGKDLKNIGLLDIIKMIHEIDGIKRIR
LSSIEPTFLTEEFVKEIANLPKMCRHYHVSLQSGCDETLKRMGRRYTTKEYKSVIDRLREYIKDVAITTDVMVGFPGETE
EEFLKTYKFVEEICFSKMHVFKYSRRKGTRAYNFPNQVANHIKEDRSKKLIELSNRCEYKFMESFIGKTLEVLFEQPVKN
MEGYVEGLTDNYLSIAVKGDIKLLRNEIFPVKIKEIKDNFLIGEIEGI

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=385, Percent_Identity=31.1688311688312, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI28872784, Length=439, Percent_Identity=26.6514806378132, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI28872782, Length=439, Percent_Identity=26.6514806378132, Blast_Score=162, Evalue=4e-40,
Organism=Escherichia coli, GI1786882, Length=445, Percent_Identity=29.438202247191, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1787057, Length=395, Percent_Identity=28.1012658227848, Blast_Score=159, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17553146, Length=449, Percent_Identity=26.0579064587973, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI71996771, Length=274, Percent_Identity=27.7372262773723, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356207, Length=448, Percent_Identity=25.2232142857143, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI19922432, Length=434, Percent_Identity=28.8018433179723, Blast_Score=159, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 51945; Mature: 51813

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVDLSLKRNGHKKAVAFYTLGCKVNQYETEVMAELFKKAGYEVVDFDEKADVYVINTC
CCCEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEE
TVTNRSDMKSRQEIRKARKKNPDALVVAVGCYVQVSPEEAFSLPEVDIAIGTKNKDKIVE
EECCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECHHHHCCCCCEEEEECCCCHHHHHH
LVEEFTQKNQKLSVVNNIMTQKEYEEFGVTAYTERTRAYIKIQDGCNQYCTYCIIPYARG
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEECCCCCCHHHEEEEECCCC
PVRSRDPKKVLDEVKRFADSGYKEIVLTGIHIASYGKDLKNIGLLDIIKMIHEIDGIKRI
CCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCHHHHCCHHHHHHHHHHHCCHHEE
RLSSIEPTFLTEEFVKEIANLPKMCRHYHVSLQSGCDETLKRMGRRYTTKEYKSVIDRLR
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHH
EYIKDVAITTDVMVGFPGETEEEFLKTYKFVEEICFSKMHVFKYSRRKGTRAYNFPNQVA
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
NHIKEDRSKKLIELSNRCEYKFMESFIGKTLEVLFEQPVKNMEGYVEGLTDNYLSIAVKG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
DIKLLRNEIFPVKIKEIKDNFLIGEIEGI
HHHHHHHCCCCEEHEECCCCEEEEEECCC
>Mature Secondary Structure 
TRVDLSLKRNGHKKAVAFYTLGCKVNQYETEVMAELFKKAGYEVVDFDEKADVYVINTC
CCEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEE
TVTNRSDMKSRQEIRKARKKNPDALVVAVGCYVQVSPEEAFSLPEVDIAIGTKNKDKIVE
EECCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECHHHHCCCCCEEEEECCCCHHHHHH
LVEEFTQKNQKLSVVNNIMTQKEYEEFGVTAYTERTRAYIKIQDGCNQYCTYCIIPYARG
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEECCCCCCHHHEEEEECCCC
PVRSRDPKKVLDEVKRFADSGYKEIVLTGIHIASYGKDLKNIGLLDIIKMIHEIDGIKRI
CCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCHHHHCCHHHHHHHHHHHCCHHEE
RLSSIEPTFLTEEFVKEIANLPKMCRHYHVSLQSGCDETLKRMGRRYTTKEYKSVIDRLR
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHH
EYIKDVAITTDVMVGFPGETEEEFLKTYKFVEEICFSKMHVFKYSRRKGTRAYNFPNQVA
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
NHIKEDRSKKLIELSNRCEYKFMESFIGKTLEVLFEQPVKNMEGYVEGLTDNYLSIAVKG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
DIKLLRNEIFPVKIKEIKDNFLIGEIEGI
HHHHHHHCCCCEEHEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]