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The map label for this gene is cisA [H]

Identifier: 167039918

GI number: 167039918

Start: 1311640

End: 1313211

Strand: Direct

Name: cisA [H]

Synonym: Teth514_1274

Alternate gene names: 167039918

Gene position: 1311640-1313211 (Clockwise)

Preceding gene: 167039917

Following gene: 167039919

Centisome position: 53.38

GC content: 35.43

Gene sequence:

>1572_bases
ATGGCAGTTAGTAAAAATGTAATGATTATACCTGCAATAAAACGCATGGGCAACAATCGAAAAGAAGATGAAACACCAAA
ACTTCGGGTTGCTGCTTATTGTCGAGTTTCTACCGACAGTGATGAACAAGCTAGTAGTTACGAAGTGCAGATTGAACATT
ATACTGAATTTATTAAGAAAAATTCAGAGTGGGAATTTGCAGGGATCTTTGCTGATGATGGTATCAGCGGTACAAATACA
AAAAATCGTGATGAATTTAATCGAATGATTGATGAGTGCATGGCAGGGAAAATTGATATGATTATTACCAAATCAATAAG
CCGATTTGCTAGGAATACCTTAGACTGCCTACATTACATCAGAAAATTAAAAGATAAAAATATTGCGGTATATTTTGAAA
AAGAAAATATCAATACACTGGATGCCAAAGGTGAAATTATGCTAACTATTATGGCTTCCTTAGCGCAACAAGAAAGCCAG
TCATTAAGCCAGAATGTAAAGCTTGGTTATCAATACCGATACCAACAAGGAGAAGTAATGGTCAATTGCTCTAGGTTTTT
AGGATATACCAAGGATGAGAATAAGCGATTAGTAATTGTACCGGAGGAGGCTGAAATAGTTAAGAGAATTTACCGAGAAT
ATCTTGAAGGCTCCAGTATGGATAAAATTAAAAAAGGACTTGAAGCAGATGGCATACTTACAGGAGCGGGCAAAAAAAGG
TGGCATACCAGTACCATAAGGAAGATATTAAGCAATGAAAAATATATTGGTGATGCATTGCTCCAAAAAACTTACACAGT
AGATTTTCTTACAAAAAAGAGGGTTGTAAATAACGGTATCGTACCTCAATATTATGTTGAGAATAGTCATGAAGCTATTA
TCCCGCGTGAAATTTTCATGCAGGTTCAAGAAGAGTTAGTTCGTAGAAGTAAAGGACATATAAGTACTAGTGGAAAGAAA
AGAAACTTTAGTGCAAATCATGTATTTTCACAAATTATTTTCTGTGGAGAGTGTGGTGAAATATACCGTAGAGTTCATTG
GAATAACAGAGGCAAAAAATCGATTGTTTGGAGATGTGTCAGTAGGCTTGAGAATACAGGGTTAGCTTGTCATTCTCGAA
CTGTACAAGAGGACATGATAGGCTTAGCTACGGTGGATGCAATTAATAAGCTACTTGGGCAAAAAGATGACTTTTTGATT
ACCTTAAAGGAAAATATAGAAACAGTGATAAGTGAAACGGACAATAATATTGTTTCCGAGATAGATAAAAAGCTAGAGGA
ATTACAAAAAGACCTTTTGAGGCTGGCCAATTCCAAAGAAGATTATAACGATATAGCCGATGAGATTTACAGGCTCAGAG
AGGAAAGGCATAAGGCTTTAGCAGAAGAAGCTGGCAAAAAGGGCTCCAAGCAAAGGCTAGAAGATATGGAAAAATTCATT
AATGAACAATCCATCCTCCTTGAGGAGTATGATGAGCAACTAGTAAGGAGACTTATAGAGAAAATAACGGTCTATGATGA
TAAACTAACTATTGAATTTAAATCTGGTGTAGAAATTGATATAGAAAAATAA

Upstream 100 bases:

>100_bases
TCTAAGAAGTTTACCATAGGACAAGTAATTCAGAAGTATACAAATCCTTTTACACAAGCGGAGTATGTTTATAGCTTAAT
AGAAAGTGAGGGACAGTAAG

Downstream 100 bases:

>100_bases
AATGAACTTGACCGCCGATTGAGGAGAAATACTTCTTGATGGGCGGTTCTTTTCTATTTATACTTGGGGATAATCTAATA
AGTGAACTCGTTTCAGCAAG

Product: resolvase domain-containing protein

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MAVSKNVMIIPAIKRMGNNRKEDETPKLRVAAYCRVSTDSDEQASSYEVQIEHYTEFIKKNSEWEFAGIFADDGISGTNT
KNRDEFNRMIDECMAGKIDMIITKSISRFARNTLDCLHYIRKLKDKNIAVYFEKENINTLDAKGEIMLTIMASLAQQESQ
SLSQNVKLGYQYRYQQGEVMVNCSRFLGYTKDENKRLVIVPEEAEIVKRIYREYLEGSSMDKIKKGLEADGILTGAGKKR
WHTSTIRKILSNEKYIGDALLQKTYTVDFLTKKRVVNNGIVPQYYVENSHEAIIPREIFMQVQEELVRRSKGHISTSGKK
RNFSANHVFSQIIFCGECGEIYRRVHWNNRGKKSIVWRCVSRLENTGLACHSRTVQEDMIGLATVDAINKLLGQKDDFLI
TLKENIETVISETDNNIVSEIDKKLEELQKDLLRLANSKEDYNDIADEIYRLREERHKALAEEAGKKGSKQRLEDMEKFI
NEQSILLEEYDEQLVRRLIEKITVYDDKLTIEFKSGVEIDIEK

Sequences:

>Translated_523_residues
MAVSKNVMIIPAIKRMGNNRKEDETPKLRVAAYCRVSTDSDEQASSYEVQIEHYTEFIKKNSEWEFAGIFADDGISGTNT
KNRDEFNRMIDECMAGKIDMIITKSISRFARNTLDCLHYIRKLKDKNIAVYFEKENINTLDAKGEIMLTIMASLAQQESQ
SLSQNVKLGYQYRYQQGEVMVNCSRFLGYTKDENKRLVIVPEEAEIVKRIYREYLEGSSMDKIKKGLEADGILTGAGKKR
WHTSTIRKILSNEKYIGDALLQKTYTVDFLTKKRVVNNGIVPQYYVENSHEAIIPREIFMQVQEELVRRSKGHISTSGKK
RNFSANHVFSQIIFCGECGEIYRRVHWNNRGKKSIVWRCVSRLENTGLACHSRTVQEDMIGLATVDAINKLLGQKDDFLI
TLKENIETVISETDNNIVSEIDKKLEELQKDLLRLANSKEDYNDIADEIYRLREERHKALAEEAGKKGSKQRLEDMEKFI
NEQSILLEEYDEQLVRRLIEKITVYDDKLTIEFKSGVEIDIEK
>Mature_522_residues
AVSKNVMIIPAIKRMGNNRKEDETPKLRVAAYCRVSTDSDEQASSYEVQIEHYTEFIKKNSEWEFAGIFADDGISGTNTK
NRDEFNRMIDECMAGKIDMIITKSISRFARNTLDCLHYIRKLKDKNIAVYFEKENINTLDAKGEIMLTIMASLAQQESQS
LSQNVKLGYQYRYQQGEVMVNCSRFLGYTKDENKRLVIVPEEAEIVKRIYREYLEGSSMDKIKKGLEADGILTGAGKKRW
HTSTIRKILSNEKYIGDALLQKTYTVDFLTKKRVVNNGIVPQYYVENSHEAIIPREIFMQVQEELVRRSKGHISTSGKKR
NFSANHVFSQIIFCGECGEIYRRVHWNNRGKKSIVWRCVSRLENTGLACHSRTVQEDMIGLATVDAINKLLGQKDDFLIT
LKENIETVISETDNNIVSEIDKKLEELQKDLLRLANSKEDYNDIADEIYRLREERHKALAEEAGKKGSKQRLEDMEKFIN
EQSILLEEYDEQLVRRLIEKITVYDDKLTIEFKSGVEIDIEK

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 60508; Mature: 60377

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSKNVMIIPAIKRMGNNRKEDETPKLRVAAYCRVSTDSDEQASSYEVQIEHYTEFIKK
CCCCCCEEEEECHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEHHHHHHHHHC
NSEWEFAGIFADDGISGTNTKNRDEFNRMIDECMAGKIDMIITKSISRFARNTLDCLHYI
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RKLKDKNIAVYFEKENINTLDAKGEIMLTIMASLAQQESQSLSQNVKLGYQYRYQQGEVM
HHHCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEE
VNCSRFLGYTKDENKRLVIVPEEAEIVKRIYREYLEGSSMDKIKKGLEADGILTGAGKKR
EEEHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCCCCH
WHTSTIRKILSNEKYIGDALLQKTYTVDFLTKKRVVNNGIVPQYYVENSHEAIIPREIFM
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHH
QVQEELVRRSKGHISTSGKKRNFSANHVFSQIIFCGECGEIYRRVHWNNRGKKSIVWRCV
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHH
SRLENTGLACHSRTVQEDMIGLATVDAINKLLGQKDDFLITLKENIETVISETDNNIVSE
HHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCHHHHH
IDKKLEELQKDLLRLANSKEDYNDIADEIYRLREERHKALAEEAGKKGSKQRLEDMEKFI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
NEQSILLEEYDEQLVRRLIEKITVYDDKLTIEFKSGVEIDIEK
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECC
>Mature Secondary Structure 
AVSKNVMIIPAIKRMGNNRKEDETPKLRVAAYCRVSTDSDEQASSYEVQIEHYTEFIKK
CCCCCEEEEECHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEHHHHHHHHHC
NSEWEFAGIFADDGISGTNTKNRDEFNRMIDECMAGKIDMIITKSISRFARNTLDCLHYI
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RKLKDKNIAVYFEKENINTLDAKGEIMLTIMASLAQQESQSLSQNVKLGYQYRYQQGEVM
HHHCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEE
VNCSRFLGYTKDENKRLVIVPEEAEIVKRIYREYLEGSSMDKIKKGLEADGILTGAGKKR
EEEHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCCCCH
WHTSTIRKILSNEKYIGDALLQKTYTVDFLTKKRVVNNGIVPQYYVENSHEAIIPREIFM
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHH
QVQEELVRRSKGHISTSGKKRNFSANHVFSQIIFCGECGEIYRRVHWNNRGKKSIVWRCV
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHH
SRLENTGLACHSRTVQEDMIGLATVDAINKLLGQKDDFLITLKENIETVISETDNNIVSE
HHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCHHHHH
IDKKLEELQKDLLRLANSKEDYNDIADEIYRLREERHKALAEEAGKKGSKQRLEDMEKFI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
NEQSILLEEYDEQLVRRLIEKITVYDDKLTIEFKSGVEIDIEK
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]