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The map label for this gene is ltrA [H]

Identifier: 167039890

GI number: 167039890

Start: 1287128

End: 1288411

Strand: Direct

Name: ltrA [H]

Synonym: Teth514_1245

Alternate gene names: 167039890

Gene position: 1287128-1288411 (Clockwise)

Preceding gene: 167039889

Following gene: 167039891

Centisome position: 52.38

GC content: 46.18

Gene sequence:

>1284_bases
ATGGGAACAAAGAGAGCAGAGATAAGCGAAATCATAGCTAAATACGGAAAAGTGCAGAATCTGATAAGCTATGTAAACCC
CGAAACACTCAAAGCCAAGCACGAGGAGATGCCCAAAAAGAAAGCGTCAGGAGTGGACAAAGTAACATGGGAAGAATACG
ATGTGAACGTGGACGAGAACGTAGAAACGCTCATAGCGAAAATGAAGCGGTTCAGCTATCGACCCCAGCCCGCAAGACGA
GTCTACATCCCAAAAGCCAACGGAAAGCTGAGGCCGCTGGGGATACCGTGTTACGAAGACAAACTGGTAGCAGCGGTTAT
GGCAGACATACTAAACGAAGTGTACGAAAACATATTTCTAGACACATCGTACGGGTTCAGGCCAGGCAGGAGCTGTCACG
ACGCAATAAAAGAACTCAATCGCATAATAGGGAGATGCAAAATAAGCTATGTGCTTGAAGCGGACATCAAAGGATTCTTC
GATAACGTAGACCAGAAACAGCTGATGGAGTTCATCGCACACGACATCGACGATAAGAACTTCAGCAGGTACATTGTCCG
ATTTCTGAAATCAGGGATAATGGAAGAAGGCAAATACCACGAAAGCGACAAAGGGACAGCCCAAGGCTCGCCACTATCGC
CGATACTAGCCAACATATACCTGCACTACACGCTGGACGTATGGTTTGCCTATCTCAAAAGAAACGGGAAGTTCAGGGGT
GAGGCATACATAGTGCGATATGCAGATGACTTTGTGATGCTCTTTCAATACAAGAGTGACGCAGATAAGATGTACGAGGC
GCTGCCAAAGAGGATGGCGAAATTCGGGCTGGAATTGGCGATGGACAAGACGAAGATACTACCATTTGGGAGATTCGCCA
AACAAAACAGCAAAGACGGCAAGACCGAAACATTCGACTTTCTCGGCTTCACATTCAGCAACGGTACGACCAGAAACGGC
AAATACAGAGCACACATCCAGACGAACAAGAAGAAGCTCAAAGCAAAAAGGCAAGTAGTAAAGGCATGGCTCAAAGAGCA
GCAACATGCGCCGGTAGCAGAAACATTCAAGAAACTGAATCAGAAACTGCAAGGGCATGTCAACTACTATGGCATAAACG
GGAACTCAAAGATGGTAGCAAACTTCTTTATGTACGTCAAAGAAACATTCATAAAGATATTGCGAGCCAGAGGGCAGAAG
CACCCGATAAAATGGGAAGACTATCAGAGAATGTGGGACTACTATATCAAGCCGCCGAAGGTCGTAGTCAACATTTGGGT
ATGA

Upstream 100 bases:

>100_bases
GCGAGGAAGCGCATGAAAGTGTGTGGAGCCAAGGGGTCAGCTGACACACATTTCTGCGAGAGCAGAAACATAACTATTGC
ACAGGAGGCACAGAAAGGTT

Downstream 100 bases:

>100_bases
TGAGCAAAAGTATGACAATACATGTGTGTCAGAAGAGCCGTATGCGGGAAAACCGCACGTACGGTTCCGTGAGGGGCAGT
AGGCAATCCCTTCACGATAC

Product: RNA-directed DNA polymerase

Products: NA

Alternate protein names: Reverse-transcriptase; RNA maturase; DNA endonuclease [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MGTKRAEISEIIAKYGKVQNLISYVNPETLKAKHEEMPKKKASGVDKVTWEEYDVNVDENVETLIAKMKRFSYRPQPARR
VYIPKANGKLRPLGIPCYEDKLVAAVMADILNEVYENIFLDTSYGFRPGRSCHDAIKELNRIIGRCKISYVLEADIKGFF
DNVDQKQLMEFIAHDIDDKNFSRYIVRFLKSGIMEEGKYHESDKGTAQGSPLSPILANIYLHYTLDVWFAYLKRNGKFRG
EAYIVRYADDFVMLFQYKSDADKMYEALPKRMAKFGLELAMDKTKILPFGRFAKQNSKDGKTETFDFLGFTFSNGTTRNG
KYRAHIQTNKKKLKAKRQVVKAWLKEQQHAPVAETFKKLNQKLQGHVNYYGINGNSKMVANFFMYVKETFIKILRARGQK
HPIKWEDYQRMWDYYIKPPKVVVNIWV

Sequences:

>Translated_427_residues
MGTKRAEISEIIAKYGKVQNLISYVNPETLKAKHEEMPKKKASGVDKVTWEEYDVNVDENVETLIAKMKRFSYRPQPARR
VYIPKANGKLRPLGIPCYEDKLVAAVMADILNEVYENIFLDTSYGFRPGRSCHDAIKELNRIIGRCKISYVLEADIKGFF
DNVDQKQLMEFIAHDIDDKNFSRYIVRFLKSGIMEEGKYHESDKGTAQGSPLSPILANIYLHYTLDVWFAYLKRNGKFRG
EAYIVRYADDFVMLFQYKSDADKMYEALPKRMAKFGLELAMDKTKILPFGRFAKQNSKDGKTETFDFLGFTFSNGTTRNG
KYRAHIQTNKKKLKAKRQVVKAWLKEQQHAPVAETFKKLNQKLQGHVNYYGINGNSKMVANFFMYVKETFIKILRARGQK
HPIKWEDYQRMWDYYIKPPKVVVNIWV
>Mature_426_residues
GTKRAEISEIIAKYGKVQNLISYVNPETLKAKHEEMPKKKASGVDKVTWEEYDVNVDENVETLIAKMKRFSYRPQPARRV
YIPKANGKLRPLGIPCYEDKLVAAVMADILNEVYENIFLDTSYGFRPGRSCHDAIKELNRIIGRCKISYVLEADIKGFFD
NVDQKQLMEFIAHDIDDKNFSRYIVRFLKSGIMEEGKYHESDKGTAQGSPLSPILANIYLHYTLDVWFAYLKRNGKFRGE
AYIVRYADDFVMLFQYKSDADKMYEALPKRMAKFGLELAMDKTKILPFGRFAKQNSKDGKTETFDFLGFTFSNGTTRNGK
YRAHIQTNKKKLKAKRQVVKAWLKEQQHAPVAETFKKLNQKLQGHVNYYGINGNSKMVANFFMYVKETFIKILRARGQKH
PIKWEDYQRMWDYYIKPPKVVVNIWV

Specific function: Multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA. It has three activities:reverse transcriptase (RT) for intron duplication, maturase to promote splicing, and DNA endonuclease for site- specific cle

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226520, Length=158, Percent_Identity=34.8101265822785, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6226521, Length=203, Percent_Identity=31.0344827586207, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003615
- InterPro:   IPR002866
- InterPro:   IPR000477 [H]

Pfam domain/function: PF01348 Intron_maturas2; PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 49780; Mature: 49649

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50878 RT_POL ; PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTKRAEISEIIAKYGKVQNLISYVNPETLKAKHEEMPKKKASGVDKVTWEEYDVNVDEN
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHCCCCCCCCHHCCCCCCCC
VETLIAKMKRFSYRPQPARRVYIPKANGKLRPLGIPCYEDKLVAAVMADILNEVYENIFL
HHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHEE
DTSYGFRPGRSCHDAIKELNRIIGRCKISYVLEADIKGFFDNVDQKQLMEFIAHDIDDKN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHCCCCHHHHHHHHHHCCCCCH
FSRYIVRFLKSGIMEEGKYHESDKGTAQGSPLSPILANIYLHYTLDVWFAYLKRNGKFRG
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EAYIVRYADDFVMLFQYKSDADKMYEALPKRMAKFGLELAMDKTKILPFGRFAKQNSKDG
CEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHCCCCCCC
KTETFDFLGFTFSNGTTRNGKYRAHIQTNKKKLKAKRQVVKAWLKEQQHAPVAETFKKLN
CCCEEHEEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QKLQGHVNYYGINGNSKMVANFFMYVKETFIKILRARGQKHPIKWEDYQRMWDYYIKPPK
HHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCE
VVVNIWV
EEEEEEC
>Mature Secondary Structure 
GTKRAEISEIIAKYGKVQNLISYVNPETLKAKHEEMPKKKASGVDKVTWEEYDVNVDEN
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHCCCCCCCCHHCCCCCCCC
VETLIAKMKRFSYRPQPARRVYIPKANGKLRPLGIPCYEDKLVAAVMADILNEVYENIFL
HHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHEE
DTSYGFRPGRSCHDAIKELNRIIGRCKISYVLEADIKGFFDNVDQKQLMEFIAHDIDDKN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHCCCCHHHHHHHHHHCCCCCH
FSRYIVRFLKSGIMEEGKYHESDKGTAQGSPLSPILANIYLHYTLDVWFAYLKRNGKFRG
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EAYIVRYADDFVMLFQYKSDADKMYEALPKRMAKFGLELAMDKTKILPFGRFAKQNSKDG
CEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHCCCCCCC
KTETFDFLGFTFSNGTTRNGKYRAHIQTNKKKLKAKRQVVKAWLKEQQHAPVAETFKKLN
CCCEEHEEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QKLQGHVNYYGINGNSKMVANFFMYVKETFIKILRARGQKHPIKWEDYQRMWDYYIKPPK
HHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCE
VVVNIWV
EEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655550; 11157264; 10488339; 9353259; 10413481; 11731786 [H]