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The map label for this gene is murB [H]

Identifier: 167039821

GI number: 167039821

Start: 1211909

End: 1212814

Strand: Direct

Name: murB [H]

Synonym: Teth514_1176

Alternate gene names: 167039821

Gene position: 1211909-1212814 (Clockwise)

Preceding gene: 167039820

Following gene: 167039822

Centisome position: 49.32

GC content: 35.21

Gene sequence:

>906_bases
GTGATTGAGATAGTTGACAAATTGAAGGATATCCTTAGAGAAGGGAAATTGTATTTAAACGAGCCCATGAAAAGACACAC
TTCTTTTAAAATAGGTGGACCTGCAGATGTGTTAGTTGTACCAAATAATCGTAAAGAATTATTGGAAGTCATATTTTTGT
TGAAAGGAGAAAACATTCCTTTTTTTATACTAGGAAATGGTACTAATTTATTGGTAAGTGAAAAGGGCATTAGAGGAGTT
GTAATAAAATTATCCTCTTTAAGGAATGTAATGGTAGAAGGTAATAGCATAATTGCTGAAGCGGGAGCCCCTCTTTCCTA
TATTGCCAATGTGGCACTTGTACATGAACTTGCGGGATTTGAATTTGCTAGCGGGATTCCTGGCACTTTAGGTGGAGCAA
TAGTGATGAACGCAGGAGCTTATGGGCCTGAAATGAAGGACGTGGTAGAAAAGGTAGAGGTTTTAGATGAAAAAGGCAAT
ATATTGATTTTATCAAACGAAGAAATGAATTTTTCCTATAGACACAGCATTATTCAAGAAAAGGATTGGATTGTTTTAAG
AGCATGGCTTAGTTTAACAAAGGGGAAATACGAAGAAATAAAAAGCAAAATGGAGGAACTAAATGCAAAAAGAAAGGAAA
AACAGCCTTTAGAGTATCCCAGTGCCGGAAGTACTTTTAAAAGGCCACCTGGATATTATGCTGGAAAATTGATTGAGGAG
GCAGGACTTAAAGGTTATTCAATTGGAGGGGCTAAAGTTTCTGAAAAGCATTCGGGATTTATTATAAATACTGGCAATGC
AACTTTTTACGATGTTTTAAATTTGATTGAGCATATACAAAAAGTAGTAAAAGAAAAGTTTGGAGTGGAACTTGTACCAG
AAATAAAAATAGTAGGAGAGAAATAG

Upstream 100 bases:

>100_bases
TATAAAATTGCATATAAAGTTTCATTTTGGAATGAAAACAATATATTATTGATAGACTATAGATGGAGTAGTTAAACTTT
AAATTTTGAGGAGTGGTAGA

Downstream 100 bases:

>100_bases
GTGATTAGACAAATGAGAATTTTTGCTGATTATCACACCCATACGGTATACAGCCATGGCAAAGGTACAATAGAGGATAA
TGTGAAAAGGGCAATAGAAA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIEIVDKLKDILREGKLYLNEPMKRHTSFKIGGPADVLVVPNNRKELLEVIFLLKGENIPFFILGNGTNLLVSEKGIRGV
VIKLSSLRNVMVEGNSIIAEAGAPLSYIANVALVHELAGFEFASGIPGTLGGAIVMNAGAYGPEMKDVVEKVEVLDEKGN
ILILSNEEMNFSYRHSIIQEKDWIVLRAWLSLTKGKYEEIKSKMEELNAKRKEKQPLEYPSAGSTFKRPPGYYAGKLIEE
AGLKGYSIGGAKVSEKHSGFIINTGNATFYDVLNLIEHIQKVVKEKFGVELVPEIKIVGEK

Sequences:

>Translated_301_residues
MIEIVDKLKDILREGKLYLNEPMKRHTSFKIGGPADVLVVPNNRKELLEVIFLLKGENIPFFILGNGTNLLVSEKGIRGV
VIKLSSLRNVMVEGNSIIAEAGAPLSYIANVALVHELAGFEFASGIPGTLGGAIVMNAGAYGPEMKDVVEKVEVLDEKGN
ILILSNEEMNFSYRHSIIQEKDWIVLRAWLSLTKGKYEEIKSKMEELNAKRKEKQPLEYPSAGSTFKRPPGYYAGKLIEE
AGLKGYSIGGAKVSEKHSGFIINTGNATFYDVLNLIEHIQKVVKEKFGVELVPEIKIVGEK
>Mature_301_residues
MIEIVDKLKDILREGKLYLNEPMKRHTSFKIGGPADVLVVPNNRKELLEVIFLLKGENIPFFILGNGTNLLVSEKGIRGV
VIKLSSLRNVMVEGNSIIAEAGAPLSYIANVALVHELAGFEFASGIPGTLGGAIVMNAGAYGPEMKDVVEKVEVLDEKGN
ILILSNEEMNFSYRHSIIQEKDWIVLRAWLSLTKGKYEEIKSKMEELNAKRKEKQPLEYPSAGSTFKRPPGYYAGKLIEE
AGLKGYSIGGAKVSEKHSGFIINTGNATFYDVLNLIEHIQKVVKEKFGVELVPEIKIVGEK

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33257; Mature: 33257

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEIVDKLKDILREGKLYLNEPMKRHTSFKIGGPADVLVVPNNRKELLEVIFLLKGENIP
CCCHHHHHHHHHHCCCEEECCHHHHHCCEEECCCEEEEEECCCHHHHHHHHHHHCCCCCC
FFILGNGTNLLVSEKGIRGVVIKLSSLRNVMVEGNSIIAEAGAPLSYIANVALVHELAGF
EEEEECCCEEEEECCCCCEEEEEHHHHHHEEECCCEEEEECCCCHHHHHHHHHHHHHHCC
EFASGIPGTLGGAIVMNAGAYGPEMKDVVEKVEVLDEKGNILILSNEEMNFSYRHSIIQE
HHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCC
KDWIVLRAWLSLTKGKYEEIKSKMEELNAKRKEKQPLEYPSAGSTFKRPPGYYAGKLIEE
CCCEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
AGLKGYSIGGAKVSEKHSGFIINTGNATFYDVLNLIEHIQKVVKEKFGVELVPEIKIVGE
CCCCEEECCCCEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEECCEEEECC
K
C
>Mature Secondary Structure
MIEIVDKLKDILREGKLYLNEPMKRHTSFKIGGPADVLVVPNNRKELLEVIFLLKGENIP
CCCHHHHHHHHHHCCCEEECCHHHHHCCEEECCCEEEEEECCCHHHHHHHHHHHCCCCCC
FFILGNGTNLLVSEKGIRGVVIKLSSLRNVMVEGNSIIAEAGAPLSYIANVALVHELAGF
EEEEECCCEEEEECCCCCEEEEEHHHHHHEEECCCEEEEECCCCHHHHHHHHHHHHHHCC
EFASGIPGTLGGAIVMNAGAYGPEMKDVVEKVEVLDEKGNILILSNEEMNFSYRHSIIQE
HHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCC
KDWIVLRAWLSLTKGKYEEIKSKMEELNAKRKEKQPLEYPSAGSTFKRPPGYYAGKLIEE
CCCEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
AGLKGYSIGGAKVSEKHSGFIINTGNATFYDVLNLIEHIQKVVKEKFGVELVPEIKIVGE
CCCCEEECCCCEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEECCEEEECC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]