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The map label for this gene is ubiB [C]

Identifier: 167039817

GI number: 167039817

Start: 1208005

End: 1209681

Strand: Direct

Name: ubiB [C]

Synonym: Teth514_1172

Alternate gene names: 167039817

Gene position: 1208005-1209681 (Clockwise)

Preceding gene: 167039816

Following gene: 167039818

Centisome position: 49.16

GC content: 33.15

Gene sequence:

>1677_bases
ATGCAACATTTAAGAAGATACAGAGAAATAGTGTTTGTATTTATCAAATATGGGTTTGGTGCTATAATTGACAATATTGG
CATTCTAAAACATATTAATGTAAGAAGAAAAATCTTGAAGCAAACAAATGATGAAAATATTGCGAAACTTTCCCGTGGAG
AAAGATTAAGACTTGCTCTTGAAGAATTAGGACCTACTTTTATAAAAATGGGGCAGATTTTAAGTACCAGGCCTGACATT
TTGCCAAAGGATGTTATAAAAGAATTGGAAAAATTACAGGACAAAGTTCCTGCTTTTTCTTTTGATGAGGTGAAATCAGT
TATACAAAATGAATTTGGCGAAAGTTTGGAGGAAGCCTATGCTGAATTTGAGCCTACTCCTTTAGCGGCTGCTTCTATAG
CACAAGTTCATATGGCTTTGTTGTGGTCAGGCAAAACTGTTGTTGTCAAAGTTCAAAGGCCAGGGATAGAAAAAATCATA
GCCCAAGATATGAGGATATTAGAAGATATTGCCAAATTTGTTGATAATCATACAAAATATGGCAAACTATATAATTTTAC
AAAAATGGTAGAAGACTTCAAAAAGAGATTGGAAGAGGAATTAGATTTTAGAATAGAGGGGGAAAACGCAGAAAAGTTCA
AAAAGAATTTTTTAAAAGACAAAAAAGTCAAAATTCCTTCTATAATCTGGACCCATACGACAAGACGTGTATTGACGATG
GAATACATTGATGGCATTCCGTTAAATGATTTTAATGCAATTGATGAGGCTGGATTAGACCGCGGTGCAATTGCAAGAAA
CCTTGCAAAATCTGTATTGAATCAGATTTTAAGGGATGGTTTTTTTCATGGAGACCCTCATCCGGGAAATATTATGGTGC
TAGGGGATGGGACAATAGCATTTTTAGATTTTGGAATGGTAGGTAGCTTAAGCCCAGAAAGAAAAAGGCAGTTTTCTAAA
ATGTTGTTGGGGATTGTTTACAAAAATAGCAGGATGATTACTGAAAGCATTATAGATTTAAATGCTGTGACTCTAAATGT
CAATATGAAAAAGCTAGAAAAAGACATAAATAATTTGCGAGATAGATATGTTGAAATACCATTAGAAAAGCTCAAAGTTG
GGGAAGTCCTCAATGGGATATTTGACCTTGTATTTTCGTATAATATTGTAATTCCCAATGAATTTAATATGCTGGCTAAA
AGCCTTATAACGTTAGAGGGAATAGTAGAAAAGTTAGATCCTAAAATTAGCGTTTTAGAAGTGGCAAAACCAATTGCAAA
GCAGTTGATACCTAAAATGTTTTCTACTCAACATATGAAAGAAGAGATAATAAATGCCACAATGGATTATAGCAGATTGA
TAAAAGAGTTGCCATCATTTTTATTGAATTTTTTAAGGAAAACAGAAGAAGAAAATTATGCTGTAGAATTGAAAATAAGA
GACTTTGAAAATTTAGAGAAACGCGTTGATAAGGTATTTAATCGACTTTCCACCAGTATTATACTTTTGGCTTTAAGTAT
TGTTATTGCAGGGATTTTAATAGGGTCAGGAATTAGTGCTAATGCTGGTGCAGAATTGTATGAGCTTAATGGGATAATTT
TAAAGATTGGTTTAGCGATAGCTTTTGTCATGGTATTAGGTTTAGCAATTTCTATTTTCCGATCTGGGTGGCTTTAA

Upstream 100 bases:

>100_bases
ATAAGAAATATTGTTCGTGAAGAAATTAAAAAAGTGCTGGAGGAAATGCAAAACACAAAGAAATAAGTAACTATAAAATT
TTGATGACAGGTGTGAAATA

Downstream 100 bases:

>100_bases
TAAATAAACTTCAAAAGGGGAAATCCAAGATGGAAGAAAGAAACCAATCACAAAGAATATTAAATGCTGCATATAAATGC
ATTTCAACTAAAGGCTATGC

Product: 2-polyprenylphenol 6-hydroxylase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MQHLRRYREIVFVFIKYGFGAIIDNIGILKHINVRRKILKQTNDENIAKLSRGERLRLALEELGPTFIKMGQILSTRPDI
LPKDVIKELEKLQDKVPAFSFDEVKSVIQNEFGESLEEAYAEFEPTPLAAASIAQVHMALLWSGKTVVVKVQRPGIEKII
AQDMRILEDIAKFVDNHTKYGKLYNFTKMVEDFKKRLEEELDFRIEGENAEKFKKNFLKDKKVKIPSIIWTHTTRRVLTM
EYIDGIPLNDFNAIDEAGLDRGAIARNLAKSVLNQILRDGFFHGDPHPGNIMVLGDGTIAFLDFGMVGSLSPERKRQFSK
MLLGIVYKNSRMITESIIDLNAVTLNVNMKKLEKDINNLRDRYVEIPLEKLKVGEVLNGIFDLVFSYNIVIPNEFNMLAK
SLITLEGIVEKLDPKISVLEVAKPIAKQLIPKMFSTQHMKEEIINATMDYSRLIKELPSFLLNFLRKTEEENYAVELKIR
DFENLEKRVDKVFNRLSTSIILLALSIVIAGILIGSGISANAGAELYELNGIILKIGLAIAFVMVLGLAISIFRSGWL

Sequences:

>Translated_558_residues
MQHLRRYREIVFVFIKYGFGAIIDNIGILKHINVRRKILKQTNDENIAKLSRGERLRLALEELGPTFIKMGQILSTRPDI
LPKDVIKELEKLQDKVPAFSFDEVKSVIQNEFGESLEEAYAEFEPTPLAAASIAQVHMALLWSGKTVVVKVQRPGIEKII
AQDMRILEDIAKFVDNHTKYGKLYNFTKMVEDFKKRLEEELDFRIEGENAEKFKKNFLKDKKVKIPSIIWTHTTRRVLTM
EYIDGIPLNDFNAIDEAGLDRGAIARNLAKSVLNQILRDGFFHGDPHPGNIMVLGDGTIAFLDFGMVGSLSPERKRQFSK
MLLGIVYKNSRMITESIIDLNAVTLNVNMKKLEKDINNLRDRYVEIPLEKLKVGEVLNGIFDLVFSYNIVIPNEFNMLAK
SLITLEGIVEKLDPKISVLEVAKPIAKQLIPKMFSTQHMKEEIINATMDYSRLIKELPSFLLNFLRKTEEENYAVELKIR
DFENLEKRVDKVFNRLSTSIILLALSIVIAGILIGSGISANAGAELYELNGIILKIGLAIAFVMVLGLAISIFRSGWL
>Mature_558_residues
MQHLRRYREIVFVFIKYGFGAIIDNIGILKHINVRRKILKQTNDENIAKLSRGERLRLALEELGPTFIKMGQILSTRPDI
LPKDVIKELEKLQDKVPAFSFDEVKSVIQNEFGESLEEAYAEFEPTPLAAASIAQVHMALLWSGKTVVVKVQRPGIEKII
AQDMRILEDIAKFVDNHTKYGKLYNFTKMVEDFKKRLEEELDFRIEGENAEKFKKNFLKDKKVKIPSIIWTHTTRRVLTM
EYIDGIPLNDFNAIDEAGLDRGAIARNLAKSVLNQILRDGFFHGDPHPGNIMVLGDGTIAFLDFGMVGSLSPERKRQFSK
MLLGIVYKNSRMITESIIDLNAVTLNVNMKKLEKDINNLRDRYVEIPLEKLKVGEVLNGIFDLVFSYNIVIPNEFNMLAK
SLITLEGIVEKLDPKISVLEVAKPIAKQLIPKMFSTQHMKEEIINATMDYSRLIKELPSFLLNFLRKTEEENYAVELKIR
DFENLEKRVDKVFNRLSTSIILLALSIVIAGILIGSGISANAGAELYELNGIILKIGLAIAFVMVLGLAISIFRSGWL

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=275, Percent_Identity=33.8181818181818, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI41393593, Length=271, Percent_Identity=32.8413284132841, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI217035081, Length=249, Percent_Identity=32.1285140562249, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI32261307, Length=314, Percent_Identity=26.7515923566879, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI27363457, Length=244, Percent_Identity=28.2786885245902, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI217416386, Length=201, Percent_Identity=29.8507462686567, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI34147522, Length=278, Percent_Identity=24.8201438848921, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI2367309, Length=533, Percent_Identity=29.6435272045028, Blast_Score=234, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17559152, Length=268, Percent_Identity=32.8358208955224, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32565180, Length=279, Percent_Identity=25.8064516129032, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555620, Length=473, Percent_Identity=22.6215644820296, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6323282, Length=328, Percent_Identity=28.9634146341463, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6325148, Length=455, Percent_Identity=24.3956043956044, Blast_Score=117, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6321319, Length=322, Percent_Identity=24.8447204968944, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24662575, Length=255, Percent_Identity=38.0392156862745, Blast_Score=158, Evalue=9e-39,
Organism=Drosophila melanogaster, GI22024280, Length=264, Percent_Identity=33.7121212121212, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI18859849, Length=289, Percent_Identity=26.9896193771626, Blast_Score=94, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 63453; Mature: 63453

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHLRRYREIVFVFIKYGFGAIIDNIGILKHINVRRKILKQTNDENIAKLSRGERLRLAL
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHH
EELGPTFIKMGQILSTRPDILPKDVIKELEKLQDKVPAFSFDEVKSVIQNEFGESLEEAY
HHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AEFEPTPLAAASIAQVHMALLWSGKTVVVKVQRPGIEKIIAQDMRILEDIAKFVDNHTKY
HHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHH
GKLYNFTKMVEDFKKRLEEELDFRIEGENAEKFKKNFLKDKKVKIPSIIWTHTTRRVLTM
HHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHCCCCCCCCEEEEECCHHHHEEH
EYIDGIPLNDFNAIDEAGLDRGAIARNLAKSVLNQILRDGFFHGDPHPGNIMVLGDGTIA
HHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEE
FLDFGMVGSLSPERKRQFSKMLLGIVYKNSRMITESIIDLNAVTLNVNMKKLEKDINNLR
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECHHHHHHHHHHHHH
DRYVEIPLEKLKVGEVLNGIFDLVFSYNIVIPNEFNMLAKSLITLEGIVEKLDPKISVLE
HHHHHCCHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
VAKPIAKQLIPKMFSTQHMKEEIINATMDYSRLIKELPSFLLNFLRKTEEENYAVELKIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
DFENLEKRVDKVFNRLSTSIILLALSIVIAGILIGSGISANAGAELYELNGIILKIGLAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCHHHHHHHHHH
AFVMVLGLAISIFRSGWL
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQHLRRYREIVFVFIKYGFGAIIDNIGILKHINVRRKILKQTNDENIAKLSRGERLRLAL
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHH
EELGPTFIKMGQILSTRPDILPKDVIKELEKLQDKVPAFSFDEVKSVIQNEFGESLEEAY
HHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AEFEPTPLAAASIAQVHMALLWSGKTVVVKVQRPGIEKIIAQDMRILEDIAKFVDNHTKY
HHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHH
GKLYNFTKMVEDFKKRLEEELDFRIEGENAEKFKKNFLKDKKVKIPSIIWTHTTRRVLTM
HHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHCCCCCCCCEEEEECCHHHHEEH
EYIDGIPLNDFNAIDEAGLDRGAIARNLAKSVLNQILRDGFFHGDPHPGNIMVLGDGTIA
HHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCEEE
FLDFGMVGSLSPERKRQFSKMLLGIVYKNSRMITESIIDLNAVTLNVNMKKLEKDINNLR
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECHHHHHHHHHHHHH
DRYVEIPLEKLKVGEVLNGIFDLVFSYNIVIPNEFNMLAKSLITLEGIVEKLDPKISVLE
HHHHHCCHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
VAKPIAKQLIPKMFSTQHMKEEIINATMDYSRLIKELPSFLLNFLRKTEEENYAVELKIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
DFENLEKRVDKVFNRLSTSIILLALSIVIAGILIGSGISANAGAELYELNGIILKIGLAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCHHHHHHHHHH
AFVMVLGLAISIFRSGWL
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]