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The map label for this gene is glcK [H]

Identifier: 167039711

GI number: 167039711

Start: 1098694

End: 1099632

Strand: Direct

Name: glcK [H]

Synonym: Teth514_1061

Alternate gene names: 167039711

Gene position: 1098694-1099632 (Clockwise)

Preceding gene: 167039710

Following gene: 167039712

Centisome position: 44.71

GC content: 38.98

Gene sequence:

>939_bases
ATGAGAATTGGTGTTGACCTTGGAGGCACTAATATTGCTGTTGGATTGGTGGATGAAGAGGGACGTATAGTAGCTACAGG
TAGCAGGCCGACAAAACCGGAAAGGGGTTATGAAGCAGTTGCCAAAGACATAGCGGATATAGCTATAGAACTTATTAAGA
GGAGTAATCTAAGTGGAAGTGATATTAAGTCAATGGGAATAGGAGTCCCGGGTGTAGCAGATAGCGAAAGAGGCATAGTA
ATACGAGCGGTGAATCTCTTTTGGACAAAAGTTCCTCTTGCAAAAGAAATAAGAAAATACATTGATTTGCCAATATATAT
GGACAATGATGCTAATGTAGCAGCTTTGGCAGAAGCAGCATATGGGGCTGGCAAAGGTTCTAAGTCCTCAGTGACAATTA
CCTTAGGAACAGGAGTAGGTTCTGGTTTTATCCTTGATGGTAAAATATACAATGGTGCACATCATTTTGCACCTGAGCTT
GGACACATAGTGATAGGAGACAATGGTATAAGATGTAACTGTGGTAAAATTGGATGTTTAGAGACATATGCTTCAGCAAC
TGCTTTAATAAGAGAAGGGAAAAAGGCAGTAGAGAAGAATCCCAATTCTCTTATTTTAAAATTTGCAAATGGAGATATAA
ACAGCATAACGGCTAAAAACGTAATTGATGCTGCGAAGCAGTATGATGAAGACGCCATGAGGATTTTTAATGACTATGTC
AAATACTTAGCTATTGGGATTGTAAATGTGATAAACATGTTTGACCCTGAAGTGATAATATTGGGTGGCGGAGTTGCAAA
TGCAGGGGATTTTCTCATAAAACCTCTTAAAAAAGAAGTGGCAGAGAATATTTTATTCAAAGACTTACCGTATGCTGACA
TAAGAAAAGCAGAGCTTGGAAATGATGCAGGGATCATCGGTGCTGCCATATTAAGTTAA

Upstream 100 bases:

>100_bases
AGAATGCCGGTATAACTGAGGATTTAGTGCTTAATACTGATGTTGGAAAAATAAAAGAATATCTTAAAGAGAAAAAACGG
AAAATTGGAGGAGAGGAAGA

Downstream 100 bases:

>100_bases
AGGAGGATAATTATGCAAATTCATGAACTTCACAAAAACGCAAAAGTGTCTGACGATCATGTTGCAATAAAGTTTAAAGA
TAGAATCTATAGTTACGGAG

Product: ROK family glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRIGVDLGGTNIAVGLVDEEGRIVATGSRPTKPERGYEAVAKDIADIAIELIKRSNLSGSDIKSMGIGVPGVADSERGIV
IRAVNLFWTKVPLAKEIRKYIDLPIYMDNDANVAALAEAAYGAGKGSKSSVTITLGTGVGSGFILDGKIYNGAHHFAPEL
GHIVIGDNGIRCNCGKIGCLETYASATALIREGKKAVEKNPNSLILKFANGDINSITAKNVIDAAKQYDEDAMRIFNDYV
KYLAIGIVNVINMFDPEVIILGGGVANAGDFLIKPLKKEVAENILFKDLPYADIRKAELGNDAGIIGAAILS

Sequences:

>Translated_312_residues
MRIGVDLGGTNIAVGLVDEEGRIVATGSRPTKPERGYEAVAKDIADIAIELIKRSNLSGSDIKSMGIGVPGVADSERGIV
IRAVNLFWTKVPLAKEIRKYIDLPIYMDNDANVAALAEAAYGAGKGSKSSVTITLGTGVGSGFILDGKIYNGAHHFAPEL
GHIVIGDNGIRCNCGKIGCLETYASATALIREGKKAVEKNPNSLILKFANGDINSITAKNVIDAAKQYDEDAMRIFNDYV
KYLAIGIVNVINMFDPEVIILGGGVANAGDFLIKPLKKEVAENILFKDLPYADIRKAELGNDAGIIGAAILS
>Mature_312_residues
MRIGVDLGGTNIAVGLVDEEGRIVATGSRPTKPERGYEAVAKDIADIAIELIKRSNLSGSDIKSMGIGVPGVADSERGIV
IRAVNLFWTKVPLAKEIRKYIDLPIYMDNDANVAALAEAAYGAGKGSKSSVTITLGTGVGSGFILDGKIYNGAHHFAPEL
GHIVIGDNGIRCNCGKIGCLETYASATALIREGKKAVEKNPNSLILKFANGDINSITAKNVIDAAKQYDEDAMRIFNDYV
KYLAIGIVNVINMFDPEVIILGGGVANAGDFLIKPLKKEVAENILFKDLPYADIRKAELGNDAGIIGAAILS

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=283, Percent_Identity=33.2155477031802, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI4885285, Length=283, Percent_Identity=33.2155477031802, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI298566325, Length=283, Percent_Identity=33.2155477031802, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI190014632, Length=283, Percent_Identity=33.2155477031802, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI298566312, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787363, Length=325, Percent_Identity=28, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI87081733, Length=320, Percent_Identity=27.5, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787878, Length=253, Percent_Identity=25.6916996047431, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786891, Length=306, Percent_Identity=23.8562091503268, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790522, Length=318, Percent_Identity=27.9874213836478, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87082127, Length=227, Percent_Identity=24.2290748898678, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082230, Length=272, Percent_Identity=26.4705882352941, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33018; Mature: 33018

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGVDLGGTNIAVGLVDEEGRIVATGSRPTKPERGYEAVAKDIADIAIELIKRSNLSGS
CEEEEEECCCEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
DIKSMGIGVPGVADSERGIVIRAVNLFWTKVPLAKEIRKYIDLPIYMDNDANVAALAEAA
CHHHHCCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHH
YGAGKGSKSSVTITLGTGVGSGFILDGKIYNGAHHFAPELGHIVIGDNGIRCNCGKIGCL
HCCCCCCCCEEEEEEECCCCCCEEEECEEECCHHHCCCCCCEEEECCCCCEECCCCCCHH
ETYASATALIREGKKAVEKNPNSLILKFANGDINSITAKNVIDAAKQYDEDAMRIFNDYV
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
KYLAIGIVNVINMFDPEVIILGGGVANAGDFLIKPLKKEVAENILFKDLPYADIRKAELG
HHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
NDAGIIGAAILS
CCCCCHHHHHCC
>Mature Secondary Structure
MRIGVDLGGTNIAVGLVDEEGRIVATGSRPTKPERGYEAVAKDIADIAIELIKRSNLSGS
CEEEEEECCCEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
DIKSMGIGVPGVADSERGIVIRAVNLFWTKVPLAKEIRKYIDLPIYMDNDANVAALAEAA
CHHHHCCCCCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHH
YGAGKGSKSSVTITLGTGVGSGFILDGKIYNGAHHFAPELGHIVIGDNGIRCNCGKIGCL
HCCCCCCCCEEEEEEECCCCCCEEEECEEECCHHHCCCCCCEEEECCCCCEECCCCCCHH
ETYASATALIREGKKAVEKNPNSLILKFANGDINSITAKNVIDAAKQYDEDAMRIFNDYV
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
KYLAIGIVNVINMFDPEVIILGGGVANAGDFLIKPLKKEVAENILFKDLPYADIRKAELG
HHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
NDAGIIGAAILS
CCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]