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The map label for this gene is dhaK [H]

Identifier: 167039675

GI number: 167039675

Start: 1056650

End: 1057648

Strand: Direct

Name: dhaK [H]

Synonym: Teth514_1025

Alternate gene names: 167039675

Gene position: 1056650-1057648 (Clockwise)

Preceding gene: 167039674

Following gene: 167039676

Centisome position: 43.0

GC content: 39.24

Gene sequence:

>999_bases
ATGAAAAAGTTGATTAATAATCCTAATGATGTCGTGAAAGAAATGATAGAAGGTTTGCTGGCTGCTCACCCATCTTACCT
GAGAAAGCTTGACAACATAGATGTAATTGTCAGAAAAGATGCACCTGTAGAAGGAAAAGTTGGACTTGTAAGTGGTGGCG
GCAGTGGCCATGAGCCTGCTCATGCAGGATATGTGGGCTATGGAATGTTAGATGCGGCTTGCCCTGGTGCTGTCTTTACT
TCACCTACGCCTGACCAAGTTTATGAAGCGATTAAGGCGGTGGATGGAGGAAAAGGAGTATTATTGATTATTAAAAATTA
CACAGGTGACGTAATGAATTTTGAAATGGCTAGAGAAATGGCACAGATGGAGGGAATAGAAGTAGATGAAGTGATAGTAA
ACGATGATGTTGCAGTAGAAAATAGCACTTGGACGCAGGGAAGACGTGGCATTGCTGGAACTGTTTTTGTTCACAAAATT
GCTGGTGCAAAGGCACAAGAAGGGGCTAGCTTACAAGAAGTAAAAAGAGTAGCTGAGAAAGTAATTGCAAATGTAAGGTC
AATGGGAATGGCACTAACACCCTGTACTGTTCCAGCAGCAGGGAAACCCAGCTTTACTCTTGCAGAAGATGAGATGGAGA
TTGGTATAGGAATACATGGAGAGCCTGGAACTCACAGAGAAAAAATAAAACCTGCAGATGAAATAGTAGAACATTTAATG
GAGAAAATAATAAATGACCTGCCTTATAAAGAAAATGACGAGGTTGCTGTTATGATAAACGGGCTTGGTGCAACTCCTTT
AATGGAACTTTATGTTGCGAACAGGAAAGTAGCAGAAATCTTAGAGAGTAAGAAGATCAAAGTTTACAAAACATACGTAG
GAGAATTTATGACCTCTCTTGAAATGAGTGGATTTTCTATAACATTATTAAAATTAGATGAAGAACTTAAAACATTGTTA
GATGCAAAGGCTGATACACCTGCTTTCAAACAATTATAA

Upstream 100 bases:

>100_bases
TTTTTTACTTTGTCAACAAGCTATACCTGTTCGCTACAATTTATTTGGCACGTAAATTGCATTTAAAAACTAACAAAAGT
AAATTAAGAGGAGGTAAATT

Downstream 100 bases:

>100_bases
ATTTTTAGGAGGTAGAAGATGGTTATCACAAAAAATGATGTCCTAAAAATTGTGGACAAAATTGTAGAGGTTATAAAAGA
AAATAAAGAGTACCTTACAG

Product: dihydroxyacetone kinase subunit DhaK

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKKLINNPNDVVKEMIEGLLAAHPSYLRKLDNIDVIVRKDAPVEGKVGLVSGGGSGHEPAHAGYVGYGMLDAACPGAVFT
SPTPDQVYEAIKAVDGGKGVLLIIKNYTGDVMNFEMAREMAQMEGIEVDEVIVNDDVAVENSTWTQGRRGIAGTVFVHKI
AGAKAQEGASLQEVKRVAEKVIANVRSMGMALTPCTVPAAGKPSFTLAEDEMEIGIGIHGEPGTHREKIKPADEIVEHLM
EKIINDLPYKENDEVAVMINGLGATPLMELYVANRKVAEILESKKIKVYKTYVGEFMTSLEMSGFSITLLKLDEELKTLL
DAKADTPAFKQL

Sequences:

>Translated_332_residues
MKKLINNPNDVVKEMIEGLLAAHPSYLRKLDNIDVIVRKDAPVEGKVGLVSGGGSGHEPAHAGYVGYGMLDAACPGAVFT
SPTPDQVYEAIKAVDGGKGVLLIIKNYTGDVMNFEMAREMAQMEGIEVDEVIVNDDVAVENSTWTQGRRGIAGTVFVHKI
AGAKAQEGASLQEVKRVAEKVIANVRSMGMALTPCTVPAAGKPSFTLAEDEMEIGIGIHGEPGTHREKIKPADEIVEHLM
EKIINDLPYKENDEVAVMINGLGATPLMELYVANRKVAEILESKKIKVYKTYVGEFMTSLEMSGFSITLLKLDEELKTLL
DAKADTPAFKQL
>Mature_332_residues
MKKLINNPNDVVKEMIEGLLAAHPSYLRKLDNIDVIVRKDAPVEGKVGLVSGGGSGHEPAHAGYVGYGMLDAACPGAVFT
SPTPDQVYEAIKAVDGGKGVLLIIKNYTGDVMNFEMAREMAQMEGIEVDEVIVNDDVAVENSTWTQGRRGIAGTVFVHKI
AGAKAQEGASLQEVKRVAEKVIANVRSMGMALTPCTVPAAGKPSFTLAEDEMEIGIGIHGEPGTHREKIKPADEIVEHLM
EKIINDLPYKENDEVAVMINGLGATPLMELYVANRKVAEILESKKIKVYKTYVGEFMTSLEMSGFSITLLKLDEELKTLL
DAKADTPAFKQL

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=336, Percent_Identity=42.5595238095238, Blast_Score=264, Evalue=9e-71,
Organism=Escherichia coli, GI87081857, Length=354, Percent_Identity=46.6101694915254, Blast_Score=333, Evalue=7e-93,
Organism=Caenorhabditis elegans, GI17565018, Length=328, Percent_Identity=35.9756097560976, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6321055, Length=321, Percent_Identity=40.4984423676012, Blast_Score=217, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6323570, Length=337, Percent_Identity=37.9821958456973, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 35910; Mature: 35910

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLINNPNDVVKEMIEGLLAAHPSYLRKLDNIDVIVRKDAPVEGKVGLVSGGGSGHEPA
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCCCC
HAGYVGYGMLDAACPGAVFTSPTPDQVYEAIKAVDGGKGVLLIIKNYTGDVMNFEMAREM
CCCEECCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHH
AQMEGIEVDEVIVNDDVAVENSTWTQGRRGIAGTVFVHKIAGAKAQEGASLQEVKRVAEK
HHHCCCCHHHEEECCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VIANVRSMGMALTPCTVPAAGKPSFTLAEDEMEIGIGIHGEPGTHREKIKPADEIVEHLM
HHHHHHHCCEEECCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCHHHCCCHHHHHHHHH
EKIINDLPYKENDEVAVMINGLGATPLMELYVANRKVAEILESKKIKVYKTYVGEFMTSL
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
EMSGFSITLLKLDEELKTLLDAKADTPAFKQL
HCCCCEEEEEECCHHHHHHHHCCCCCCHHHCC
>Mature Secondary Structure
MKKLINNPNDVVKEMIEGLLAAHPSYLRKLDNIDVIVRKDAPVEGKVGLVSGGGSGHEPA
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCCCCC
HAGYVGYGMLDAACPGAVFTSPTPDQVYEAIKAVDGGKGVLLIIKNYTGDVMNFEMAREM
CCCEECCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHH
AQMEGIEVDEVIVNDDVAVENSTWTQGRRGIAGTVFVHKIAGAKAQEGASLQEVKRVAEK
HHHCCCCHHHEEECCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VIANVRSMGMALTPCTVPAAGKPSFTLAEDEMEIGIGIHGEPGTHREKIKPADEIVEHLM
HHHHHHHCCEEECCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCHHHCCCHHHHHHHHH
EKIINDLPYKENDEVAVMINGLGATPLMELYVANRKVAEILESKKIKVYKTYVGEFMTSL
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
EMSGFSITLLKLDEELKTLLDAKADTPAFKQL
HCCCCEEEEEECCHHHHHHHHCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]