Click here to switch to the map view.

The map label for this gene is yqiR [H]

Identifier: 167039674

GI number: 167039674

Start: 1054598

End: 1056232

Strand: Direct

Name: yqiR [H]

Synonym: Teth514_1024

Alternate gene names: 167039674

Gene position: 1054598-1056232 (Clockwise)

Preceding gene: 167039673

Following gene: 167039675

Centisome position: 42.92

GC content: 33.27

Gene sequence:

>1635_bases
ATGGAGGGAAGAAGGGAAATATTAAGAACTCCTGTGAGTATCCATTCTCAGATTGCTGCCCATATTGTTCAAAAGGTTAG
TCACATAAGCAGACAAAACAATGTAAGCATATTTTTAAGGAAGATAAATGACAATAGGTTGATTCCTGCAAATAGTATGT
TATCAATGGTGACTTTTTTTGCTTCTCGGGGAGAAGAAATAGAAGTAGTGGTAGAAGGAGCAAATGTGGACAATGCTATA
AAAGAGTTTAAAGGCTTTTTTTACAACGAGTTAGGGAAAGAAAAGGAAGAAAAAACTACTTATGAACTTTTAAAAAATAC
CTCAATAGCCTATGAGAAAATATTTAATTCTATTGGCTCAGGACTTATAGTTACTGATGAAAATGGGGCAATAATGATTT
TTAACAAAGCAGCTGAAAGTATTACAGGGATTAATATGGACCAGGCTATAGGGAAAAAAATACAAGAAGTGATGTCGGAT
ATAAAAATTGCTGATGTGTTAAAAACTGGCAAAGAAGAGATGAATAAAAAACTAAAAATAGGCACAAATGTGGTGTTAAC
AAATATAACACCTATTTATACAGGTACAAAAATAGAAGGGGCGGTTATAGTATTTTATGACTTCCCTCAAATAGAATATT
TGGAAAATGAGCTAAAAAGAGATAGAAAACTTGACAAAGCTTTTGACATAATAATAGGCAATAGCGGAAAATTAAAAGAC
GCTCTTACTATTGCTTCTAAAGCTGCAGAAACTGATTCAACAGTCCTCATAAGAGGGGAAAGCGGAACGGGGAAAGAGCT
GGTGGCTAATGCGATACATTACGCCAGTAAGAGAAAGGATAAACCATTTATAAGGGTAAATTGTGCGGCTATTCCTGTGA
CTCTATTGGAGAGTGAACTTTTTGGGCATGAAAGAGGAGCTTTTACTGGAGCTGTAACTCAAAAGATAGGAAAATTCGAA
TTAGCAGATGGAGGAACGATATTTCTTGATGAAATAGGAGATATTCCACCTGAGATTCAGGTAAAGCTTTTGAGAGTGAT
TCAAGAAAAGGAATTTGAAAGAGTAGGGGGAATAAAAACTATAAAAGTAGATGTGAGGATAATCGCTGCGACAAATAAAG
ATTTAGAAAAAGCAATAAAAGAGGGGACTTTTAGAGAAGATTTATACTATAGATTAAACGTTATACCTGTGATTTTGCCT
CCATTAAGGGAAAGAAGAGGAGATATTCCTCTACTTGTCGAACATTTTATAGAAAAGCTGAACAAAAAACTAAACAAAAA
TGTAAAAAAGGTTACGAAAAAAGCTATGCAAGCATTGATATATTATGATTGGCCTGGGAATATACGAGAATTAGAAAATA
TAATTGAAAGGTGTATAACATTAAGTGATACTGATTACATCGATTATGAAGATTTGCCCCAATATATTCGAAATGAAACT
ACTACTGTATCAGATGATGATATTATTTATCTTGGAGAAAATAGTGAGCTACTTACAATGGAGGAATATGAGTATAAAAT
AATAAAGGCTGCGATACAAAGATATAAAAGCTTTAATAAAGCAGGAAAAGTTTTAGGACTTACCCATAAAACTATTGCTG
CAAAAGCAAGGAAATTTGGACTTGTTGATAGATAA

Upstream 100 bases:

>100_bases
AAAATAGGAGATGTAGTGGTGAAGAACATTTTAGGTACGGGGGTTGACATAATTGCTACAAGAAACCTCTATGTAAAATA
AGTTTTTGCGTGGTGATAAA

Downstream 100 bases:

>100_bases
TACCAAAAGAAATAAATAGTTGATACTTTTTACCAAAATAGCCTTTGAAGGCTATTTCAGACTGTAGACAAACTTTCGTA
AATAGGATATTTTGCATAAG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MEGRREILRTPVSIHSQIAAHIVQKVSHISRQNNVSIFLRKINDNRLIPANSMLSMVTFFASRGEEIEVVVEGANVDNAI
KEFKGFFYNELGKEKEEKTTYELLKNTSIAYEKIFNSIGSGLIVTDENGAIMIFNKAAESITGINMDQAIGKKIQEVMSD
IKIADVLKTGKEEMNKKLKIGTNVVLTNITPIYTGTKIEGAVIVFYDFPQIEYLENELKRDRKLDKAFDIIIGNSGKLKD
ALTIASKAAETDSTVLIRGESGTGKELVANAIHYASKRKDKPFIRVNCAAIPVTLLESELFGHERGAFTGAVTQKIGKFE
LADGGTIFLDEIGDIPPEIQVKLLRVIQEKEFERVGGIKTIKVDVRIIAATNKDLEKAIKEGTFREDLYYRLNVIPVILP
PLRERRGDIPLLVEHFIEKLNKKLNKNVKKVTKKAMQALIYYDWPGNIRELENIIERCITLSDTDYIDYEDLPQYIRNET
TTVSDDDIIYLGENSELLTMEEYEYKIIKAAIQRYKSFNKAGKVLGLTHKTIAAKARKFGLVDR

Sequences:

>Translated_544_residues
MEGRREILRTPVSIHSQIAAHIVQKVSHISRQNNVSIFLRKINDNRLIPANSMLSMVTFFASRGEEIEVVVEGANVDNAI
KEFKGFFYNELGKEKEEKTTYELLKNTSIAYEKIFNSIGSGLIVTDENGAIMIFNKAAESITGINMDQAIGKKIQEVMSD
IKIADVLKTGKEEMNKKLKIGTNVVLTNITPIYTGTKIEGAVIVFYDFPQIEYLENELKRDRKLDKAFDIIIGNSGKLKD
ALTIASKAAETDSTVLIRGESGTGKELVANAIHYASKRKDKPFIRVNCAAIPVTLLESELFGHERGAFTGAVTQKIGKFE
LADGGTIFLDEIGDIPPEIQVKLLRVIQEKEFERVGGIKTIKVDVRIIAATNKDLEKAIKEGTFREDLYYRLNVIPVILP
PLRERRGDIPLLVEHFIEKLNKKLNKNVKKVTKKAMQALIYYDWPGNIRELENIIERCITLSDTDYIDYEDLPQYIRNET
TTVSDDDIIYLGENSELLTMEEYEYKIIKAAIQRYKSFNKAGKVLGLTHKTIAAKARKFGLVDR
>Mature_544_residues
MEGRREILRTPVSIHSQIAAHIVQKVSHISRQNNVSIFLRKINDNRLIPANSMLSMVTFFASRGEEIEVVVEGANVDNAI
KEFKGFFYNELGKEKEEKTTYELLKNTSIAYEKIFNSIGSGLIVTDENGAIMIFNKAAESITGINMDQAIGKKIQEVMSD
IKIADVLKTGKEEMNKKLKIGTNVVLTNITPIYTGTKIEGAVIVFYDFPQIEYLENELKRDRKLDKAFDIIIGNSGKLKD
ALTIASKAAETDSTVLIRGESGTGKELVANAIHYASKRKDKPFIRVNCAAIPVTLLESELFGHERGAFTGAVTQKIGKFE
LADGGTIFLDEIGDIPPEIQVKLLRVIQEKEFERVGGIKTIKVDVRIIAATNKDLEKAIKEGTFREDLYYRLNVIPVILP
PLRERRGDIPLLVEHFIEKLNKKLNKNVKKVTKKAMQALIYYDWPGNIRELENIIERCITLSDTDYIDYEDLPQYIRNET
TTVSDDDIIYLGENSELLTMEEYEYKIIKAAIQRYKSFNKAGKVLGLTHKTIAAKARKFGLVDR

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=312, Percent_Identity=48.7179487179487, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1790437, Length=307, Percent_Identity=49.8371335504886, Blast_Score=302, Evalue=4e-83,
Organism=Escherichia coli, GI87082117, Length=232, Percent_Identity=56.8965517241379, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1789087, Length=323, Percent_Identity=45.8204334365325, Blast_Score=291, Evalue=8e-80,
Organism=Escherichia coli, GI1790299, Length=348, Percent_Identity=41.6666666666667, Blast_Score=271, Evalue=1e-73,
Organism=Escherichia coli, GI1788905, Length=253, Percent_Identity=49.0118577075099, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1789233, Length=457, Percent_Identity=35.6673960612691, Blast_Score=259, Evalue=4e-70,
Organism=Escherichia coli, GI87081872, Length=320, Percent_Identity=41.875, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI87082152, Length=216, Percent_Identity=50.462962962963, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1787583, Length=433, Percent_Identity=33.7182448036951, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1786524, Length=240, Percent_Identity=46.6666666666667, Blast_Score=221, Evalue=8e-59,
Organism=Escherichia coli, GI87081858, Length=435, Percent_Identity=28.0459770114943, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI1789828, Length=294, Percent_Identity=31.9727891156463, Blast_Score=138, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 61390; Mature: 61390

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGRREILRTPVSIHSQIAAHIVQKVSHISRQNNVSIFLRKINDNRLIPANSMLSMVTFF
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEECCHHHHHHHHHHH
ASRGEEIEVVVEGANVDNAIKEFKGFFYNELGKEKEEKTTYELLKNTSIAYEKIFNSIGS
HCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCC
GLIVTDENGAIMIFNKAAESITGINMDQAIGKKIQEVMSDIKIADVLKTGKEEMNKKLKI
CEEEECCCCEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEC
GTNVVLTNITPIYTGTKIEGAVIVFYDFPQIEYLENELKRDRKLDKAFDIIIGNSGKLKD
CCEEEEECCEEEEECCEECCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHH
ALTIASKAAETDSTVLIRGESGTGKELVANAIHYASKRKDKPFIRVNCAAIPVTLLESEL
HHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHH
FGHERGAFTGAVTQKIGKFELADGGTIFLDEIGDIPPEIQVKLLRVIQEKEFERVGGIKT
HCCCCCCCHHHHHHHCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEE
IKVDVRIIAATNKDLEKAIKEGTFREDLYYRLNVIPVILPPLRERRGDIPLLVEHFIEKL
EEEEEEEEEECCHHHHHHHHCCCCHHHHHEEEEEEEEECCCHHHCCCCCCHHHHHHHHHH
NKKLNKNVKKVTKKAMQALIYYDWPGNIRELENIIERCITLSDTDYIDYEDLPQYIRNET
HHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
TTVSDDDIIYLGENSELLTMEEYEYKIIKAAIQRYKSFNKAGKVLGLTHKTIAAKARKFG
CCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHCC
LVDR
CCCC
>Mature Secondary Structure
MEGRREILRTPVSIHSQIAAHIVQKVSHISRQNNVSIFLRKINDNRLIPANSMLSMVTFF
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEECCHHHHHHHHHHH
ASRGEEIEVVVEGANVDNAIKEFKGFFYNELGKEKEEKTTYELLKNTSIAYEKIFNSIGS
HCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCC
GLIVTDENGAIMIFNKAAESITGINMDQAIGKKIQEVMSDIKIADVLKTGKEEMNKKLKI
CEEEECCCCEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEC
GTNVVLTNITPIYTGTKIEGAVIVFYDFPQIEYLENELKRDRKLDKAFDIIIGNSGKLKD
CCEEEEECCEEEEECCEECCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHH
ALTIASKAAETDSTVLIRGESGTGKELVANAIHYASKRKDKPFIRVNCAAIPVTLLESEL
HHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHH
FGHERGAFTGAVTQKIGKFELADGGTIFLDEIGDIPPEIQVKLLRVIQEKEFERVGGIKT
HCCCCCCCHHHHHHHCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEE
IKVDVRIIAATNKDLEKAIKEGTFREDLYYRLNVIPVILPPLRERRGDIPLLVEHFIEKL
EEEEEEEEEECCHHHHHHHHCCCCHHHHHEEEEEEEEECCCHHHCCCCCCHHHHHHHHHH
NKKLNKNVKKVTKKAMQALIYYDWPGNIRELENIIERCITLSDTDYIDYEDLPQYIRNET
HHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
TTVSDDDIIYLGENSELLTMEEYEYKIIKAAIQRYKSFNKAGKVLGLTHKTIAAKARKFG
CCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHCC
LVDR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]