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The map label for this gene is pfp [H]

Identifier: 167039623

GI number: 167039623

Start: 990769

End: 992013

Strand: Direct

Name: pfp [H]

Synonym: Teth514_0971

Alternate gene names: 167039623

Gene position: 990769-992013 (Clockwise)

Preceding gene: 167039621

Following gene: 167039627

Centisome position: 40.32

GC content: 34.38

Gene sequence:

>1245_bases
ATGTATACTAAAAGCAATTGTCTTATAGCACAATCAGGTGGTCCTACAGCTGTTATTAATTCCAGTCTGTATGGAGCTAT
AATGGAAGCTTCGCGCTCGGAGAAAATTGGCAAAGTTTATGGTGGGATAAACGGCATAGAAGGTATAATAAAAGGCAATA
TTATTGACATATTTGATATTCCCTATGAAAGAATAAAACAAATGAGATTTAGCCCTGCGGCTGCATTAGGGTCGTGCCGA
TATAGGTTAAAAGACTATTTAGAGGATGAAGAGGAATACAAAAAGTTAATAGAAATTTTTAAGAAATACAACATTAAATA
TTTTTTCTACATAGGTGGCAATGATTCTATGGATGCCGTTGACAAAATCAGTAAATATGCAAGAGAAATAGGTTTTGAAA
TAAATGTAATTGGAATTCCTAAGACTATTGATAACGATTTGATGTTTACAGATCATTCTCCTGGTTTTGGAAGTGCGGCA
AAATATATAGCCACAACTACTTTAGAACTTGCTTTAGATGCGGAAGTGTATGAGACTAAAACAATTAACGTACTCGAAGT
GATGGGCAGAAATGCAGGTTGGCTTACCGCTTCTTCTGCTTTGGTTAAAGAAAGATTGCCCCATTTGAAACAACTTATTT
ATCTTCCTGAGATACCTTTTAATGAGGAAAGATTTTTAGAGGATGTAAATAAAGCTTATAAGGAATATGGCAATGTCTTT
ATAACTGTGTCAGAAGGACTTATGGATGAAAAAGGGAATTACATTGGAAGAAAAGAAAATGCTTATCATAAAGATGCTTT
TGGTCATCCTCAACTGGGAGGAGTAGGAGACTATATAGAAAAGCTTGTAAAAGAGAAAATATATAAACGTGTCAAAATGA
CCAGACTTGGTGTAACGCAAAGATGTGCAATGCACTTGGCATCTAAAGTGGATTTTGAAGAAGCTGAAATGTTGGGGAGG
GAAGCAGTAAAGTATGCGTTATGTGGTGAAACCGGGAAAATGATAAGCCTTGTAAGAGAAAGAAATTACCCATACACTGT
TAAAACAGATATTGTAGATGTTGATAAAGTGTGTAACAAGGAGAAAAAAATGCCTTTAAATTGGATAAATGAAGAAGGTA
ATTATGTTACTGAAGAATTTTTTGATTATGCAAGACCACTTATACAAGGAGAAGTGAAGGTCCCTATGGCAGAAGGGTTA
CCTTATTATATAAACTTAAAATATGCGATAAAAAAGCAGGAATAA

Upstream 100 bases:

>100_bases
ATAAAATTTTATCAAAAATTATTATTATATTTCTTTTTGTGATATAATATATCTGAATTACTTTATAATTTATAATAGAA
TATCACAATGGGGGTATATT

Downstream 100 bases:

>100_bases
AATCCTGCTTTTTTTAAAATTCTTCCATTAGAACATTGCTATATTGTTTATTACTTTCTATAAACACGATAAGTATTGAT
AATATAGGGAATAATAGATT

Product: 6-phosphofructokinase

Products: NA

Alternate protein names: 6-phosphofructokinase, pyrophosphate dependent; PPi-dependent phosphofructokinase; PPi-PFK; Pyrophosphate-dependent 6-phosphofructose-1-kinase [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MYTKSNCLIAQSGGPTAVINSSLYGAIMEASRSEKIGKVYGGINGIEGIIKGNIIDIFDIPYERIKQMRFSPAAALGSCR
YRLKDYLEDEEEYKKLIEIFKKYNIKYFFYIGGNDSMDAVDKISKYAREIGFEINVIGIPKTIDNDLMFTDHSPGFGSAA
KYIATTTLELALDAEVYETKTINVLEVMGRNAGWLTASSALVKERLPHLKQLIYLPEIPFNEERFLEDVNKAYKEYGNVF
ITVSEGLMDEKGNYIGRKENAYHKDAFGHPQLGGVGDYIEKLVKEKIYKRVKMTRLGVTQRCAMHLASKVDFEEAEMLGR
EAVKYALCGETGKMISLVRERNYPYTVKTDIVDVDKVCNKEKKMPLNWINEEGNYVTEEFFDYARPLIQGEVKVPMAEGL
PYYINLKYAIKKQE

Sequences:

>Translated_414_residues
MYTKSNCLIAQSGGPTAVINSSLYGAIMEASRSEKIGKVYGGINGIEGIIKGNIIDIFDIPYERIKQMRFSPAAALGSCR
YRLKDYLEDEEEYKKLIEIFKKYNIKYFFYIGGNDSMDAVDKISKYAREIGFEINVIGIPKTIDNDLMFTDHSPGFGSAA
KYIATTTLELALDAEVYETKTINVLEVMGRNAGWLTASSALVKERLPHLKQLIYLPEIPFNEERFLEDVNKAYKEYGNVF
ITVSEGLMDEKGNYIGRKENAYHKDAFGHPQLGGVGDYIEKLVKEKIYKRVKMTRLGVTQRCAMHLASKVDFEEAEMLGR
EAVKYALCGETGKMISLVRERNYPYTVKTDIVDVDKVCNKEKKMPLNWINEEGNYVTEEFFDYARPLIQGEVKVPMAEGL
PYYINLKYAIKKQE
>Mature_414_residues
MYTKSNCLIAQSGGPTAVINSSLYGAIMEASRSEKIGKVYGGINGIEGIIKGNIIDIFDIPYERIKQMRFSPAAALGSCR
YRLKDYLEDEEEYKKLIEIFKKYNIKYFFYIGGNDSMDAVDKISKYAREIGFEINVIGIPKTIDNDLMFTDHSPGFGSAA
KYIATTTLELALDAEVYETKTINVLEVMGRNAGWLTASSALVKERLPHLKQLIYLPEIPFNEERFLEDVNKAYKEYGNVF
ITVSEGLMDEKGNYIGRKENAYHKDAFGHPQLGGVGDYIEKLVKEKIYKRVKMTRLGVTQRCAMHLASKVDFEEAEMLGR
EAVKYALCGETGKMISLVRERNYPYTVKTDIVDVDKVCNKEKKMPLNWINEEGNYVTEEFFDYARPLIQGEVKVPMAEGL
PYYINLKYAIKKQE

Specific function: Key control step of glycolysis. [C]

COG id: COG0205

COG function: function code G; 6-phosphofructokinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphofructokinase family [H]

Homologues:

Organism=Escherichia coli, GI1790350, Length=300, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: 3981 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 950 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012003
- InterPro:   IPR012829
- InterPro:   IPR022953
- InterPro:   IPR015912
- InterPro:   IPR000023 [H]

Pfam domain/function: PF00365 PFK [H]

EC number: =2.7.1.90 [H]

Molecular weight: Translated: 47108; Mature: 47108

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTKSNCLIAQSGGPTAVINSSLYGAIMEASRSEKIGKVYGGINGIEGIIKGNIIDIFDI
CCCCCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECC
PYERIKQMRFSPAAALGSCRYRLKDYLEDEEEYKKLIEIFKKYNIKYFFYIGGNDSMDAV
CHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
DKISKYAREIGFEINVIGIPKTIDNDLMFTDHSPGFGSAAKYIATTTLELALDAEVYETK
HHHHHHHHHHCCEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHEEEEEEECCHHHCCC
TINVLEVMGRNAGWLTASSALVKERLPHLKQLIYLPEIPFNEERFLEDVNKAYKEYGNVF
CHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEE
ITVSEGLMDEKGNYIGRKENAYHKDAFGHPQLGGVGDYIEKLVKEKIYKRVKMTRLGVTQ
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
RCAMHLASKVDFEEAEMLGREAVKYALCGETGKMISLVRERNYPYTVKTDIVDVDKVCNK
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHHCCC
EKKMPLNWINEEGNYVTEEFFDYARPLIQGEVKVPMAEGLPYYINLKYAIKKQE
CCCCCCEEECCCCCEEHHHHHHHHHHHHCCCEECCHHCCCCEEEEEEEEEECCC
>Mature Secondary Structure
MYTKSNCLIAQSGGPTAVINSSLYGAIMEASRSEKIGKVYGGINGIEGIIKGNIIDIFDI
CCCCCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECC
PYERIKQMRFSPAAALGSCRYRLKDYLEDEEEYKKLIEIFKKYNIKYFFYIGGNDSMDAV
CHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
DKISKYAREIGFEINVIGIPKTIDNDLMFTDHSPGFGSAAKYIATTTLELALDAEVYETK
HHHHHHHHHHCCEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHEEEEEEECCHHHCCC
TINVLEVMGRNAGWLTASSALVKERLPHLKQLIYLPEIPFNEERFLEDVNKAYKEYGNVF
CHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEE
ITVSEGLMDEKGNYIGRKENAYHKDAFGHPQLGGVGDYIEKLVKEKIYKRVKMTRLGVTQ
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
RCAMHLASKVDFEEAEMLGREAVKYALCGETGKMISLVRERNYPYTVKTDIVDVDKVCNK
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHHCCC
EKKMPLNWINEEGNYVTEEFFDYARPLIQGEVKVPMAEGLPYYINLKYAIKKQE
CCCCCCEEECCCCCEEHHHHHHHHHHHHCCCEECCHHCCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550409 [H]