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The map label for this gene is yhcK [H]

Identifier: 167039476

GI number: 167039476

Start: 855206

End: 856870

Strand: Direct

Name: yhcK [H]

Synonym: Teth514_0822

Alternate gene names: 167039476

Gene position: 855206-856870 (Clockwise)

Preceding gene: 167039475

Following gene: 167039477

Centisome position: 34.8

GC content: 31.95

Gene sequence:

>1665_bases
ATGGGGAAGTACAGGGAACTGGTTTTTAATATAACCTTAATTACAATAGGAAGTATATTATTTGTGTGGGCACTTTACTG
CTGTGGTATTGGAATTGATTGGAGAGTCTTTTTGATTTTATTAGCTTTCGCAATAATTTTGGATAATCTTGGCATAATGT
ATACAGATATAAAATTATCTTTAAGCCCTACAATAGGAATAACTACTTTTTTGATTTTTGGCACGGTTGGAGCGGCTACT
CTCATGGTATCCTCTGTTATGTTTGATACTATTGTAGTAAGAAAAAAGATAAAAAATGGGCTTTTAAATGGAGGAATGTT
TTCTATTGCATATTTAGTGGCAGGATGGTTTTATGAATTCATAGGTGGAAAAATTGGCATAGTTTCTTTTTCGCAAATTA
AATATATTTTAAGCTACGTCATAATAAGTTTTCTTTTGAATAATTTTATACTGTACTATGCTTTAAAAGTACAGGGGAAG
ATTTTGTTTAAAGAGTATTGGAATGAGAGTGTATTATTAGAGTTAGGTACTTATATAGTTATGATTCCTGTTTCATTACT
TCTTGCATATATTTATTTTAAACATAGCCTTCTGTTTTTTGTGTTATCTTTAACTCCACTTATATTCATAGCATATGCTT
TTAGGATGATTAGAGATTTGATTAAGGCAAATAAAAGGCTTAACGCTATATATGAGATGGTTAAAATGATAAATTCGAAG
TTAGAGTTGGAGCAAATATTAGATACTATTATAGAAGTTATTTCTCAAGTTGTTTCAGTATCTGCAGCAGCAATATATTT
GACAGATTCTAATGGGGTAGCTGCTTTAGTAAAATCGATAGGTAATAGAGAGGGAGAGGAAGGCTTTAAAGAAAATTACT
TCAAAGATGAGGGAATAATAGGAAAGTGCATATCTTCTAACAAAACAATAGCAATTAAGGATTTAAAGCAGGATAAAAGA
TTTTTAAAAGAACAATTTTTAAATAACTATGGCAGTGTAGTAGTAGCTCCTTTAAGGTCTTCGGGTTCTACCATTGGATG
TCTTGCGGTATTACATGTAGATACAAATGTTTTTGATGAGGATTCTGTTAAAATCATAGAGATAATCGTAGATCAAGCTT
CTGTTGCGATAACCAATGCTAAACGATATTATGAAGTCACCAAAAAATCTATTACTGATCCTTTAACAAAGACTTATAAT
AGAAGATATTTTAATGATGCATTAATGGAAAATATTATGAGGGCAGATGAGACTAGTGAGCCTGTGAGCCTTATAATGTT
TGATTTGGATAATTTTAAACTGATAAATGATACTTATGGCCATTTAGTTGGAGATGAAGTACTTAAGGAAGTGGCAAAAC
GGATAAAAAACAATGTGAGAAGTGATGATATTGTAGCGCGATTTGGTGGAGAAGAATTTGCAGTGATTTTGCCGAAACTT
ACTGCAGAACAAGCCTATATGATTGCAGAGAGGATAAGAAATGAAGTATTATCAAGGCCAATTAGGACAGATAAAGGAGA
TATATATGTAACCATAACGGGTGGAGTAGCAGATTATCCGGAAAAGGCTGATTCTGCAGAAAAACTTATAAGCCATGCAG
ATAGAGCTTTATATGCAGGTGGCAAAAGTAAAGGAAGAAACAAAATTGCCATATATGAAGTGTGA

Upstream 100 bases:

>100_bases
TAAATAAATGTGATCAATTTTATAAACCTTATCAGCCCAAGAAGGATTTTTGAAATAAATGTAGAATACTAATATGATTC
GGAAAAACGAGGGGATTAGT

Downstream 100 bases:

>100_bases
AAAAGGCTTAAAGAAAAGACTGGGAGAATATTTTCCTGGTCTTTTTTGTTTTATCTCTTGATTTAAATAATTGATAAAGT
TTTACCACATTAATAAGGCA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MGKYRELVFNITLITIGSILFVWALYCCGIGIDWRVFLILLAFAIILDNLGIMYTDIKLSLSPTIGITTFLIFGTVGAAT
LMVSSVMFDTIVVRKKIKNGLLNGGMFSIAYLVAGWFYEFIGGKIGIVSFSQIKYILSYVIISFLLNNFILYYALKVQGK
ILFKEYWNESVLLELGTYIVMIPVSLLLAYIYFKHSLLFFVLSLTPLIFIAYAFRMIRDLIKANKRLNAIYEMVKMINSK
LELEQILDTIIEVISQVVSVSAAAIYLTDSNGVAALVKSIGNREGEEGFKENYFKDEGIIGKCISSNKTIAIKDLKQDKR
FLKEQFLNNYGSVVVAPLRSSGSTIGCLAVLHVDTNVFDEDSVKIIEIIVDQASVAITNAKRYYEVTKKSITDPLTKTYN
RRYFNDALMENIMRADETSEPVSLIMFDLDNFKLINDTYGHLVGDEVLKEVAKRIKNNVRSDDIVARFGGEEFAVILPKL
TAEQAYMIAERIRNEVLSRPIRTDKGDIYVTITGGVADYPEKADSAEKLISHADRALYAGGKSKGRNKIAIYEV

Sequences:

>Translated_554_residues
MGKYRELVFNITLITIGSILFVWALYCCGIGIDWRVFLILLAFAIILDNLGIMYTDIKLSLSPTIGITTFLIFGTVGAAT
LMVSSVMFDTIVVRKKIKNGLLNGGMFSIAYLVAGWFYEFIGGKIGIVSFSQIKYILSYVIISFLLNNFILYYALKVQGK
ILFKEYWNESVLLELGTYIVMIPVSLLLAYIYFKHSLLFFVLSLTPLIFIAYAFRMIRDLIKANKRLNAIYEMVKMINSK
LELEQILDTIIEVISQVVSVSAAAIYLTDSNGVAALVKSIGNREGEEGFKENYFKDEGIIGKCISSNKTIAIKDLKQDKR
FLKEQFLNNYGSVVVAPLRSSGSTIGCLAVLHVDTNVFDEDSVKIIEIIVDQASVAITNAKRYYEVTKKSITDPLTKTYN
RRYFNDALMENIMRADETSEPVSLIMFDLDNFKLINDTYGHLVGDEVLKEVAKRIKNNVRSDDIVARFGGEEFAVILPKL
TAEQAYMIAERIRNEVLSRPIRTDKGDIYVTITGGVADYPEKADSAEKLISHADRALYAGGKSKGRNKIAIYEV
>Mature_553_residues
GKYRELVFNITLITIGSILFVWALYCCGIGIDWRVFLILLAFAIILDNLGIMYTDIKLSLSPTIGITTFLIFGTVGAATL
MVSSVMFDTIVVRKKIKNGLLNGGMFSIAYLVAGWFYEFIGGKIGIVSFSQIKYILSYVIISFLLNNFILYYALKVQGKI
LFKEYWNESVLLELGTYIVMIPVSLLLAYIYFKHSLLFFVLSLTPLIFIAYAFRMIRDLIKANKRLNAIYEMVKMINSKL
ELEQILDTIIEVISQVVSVSAAAIYLTDSNGVAALVKSIGNREGEEGFKENYFKDEGIIGKCISSNKTIAIKDLKQDKRF
LKEQFLNNYGSVVVAPLRSSGSTIGCLAVLHVDTNVFDEDSVKIIEIIVDQASVAITNAKRYYEVTKKSITDPLTKTYNR
RYFNDALMENIMRADETSEPVSLIMFDLDNFKLINDTYGHLVGDEVLKEVAKRIKNNVRSDDIVARFGGEEFAVILPKLT
AEQAYMIAERIRNEVLSRPIRTDKGDIYVTITGGVADYPEKADSAEKLISHADRALYAGGKSKGRNKIAIYEV

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=174, Percent_Identity=37.3563218390805, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=39.1566265060241, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787802, Length=193, Percent_Identity=33.160621761658, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1787816, Length=178, Percent_Identity=37.0786516853933, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=37.4233128834356, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1786584, Length=180, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787541, Length=187, Percent_Identity=32.620320855615, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1788085, Length=174, Percent_Identity=33.9080459770115, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788381, Length=173, Percent_Identity=32.3699421965318, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=36.7816091954023, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787056, Length=174, Percent_Identity=34.4827586206897, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081974, Length=110, Percent_Identity=35.4545454545455, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=31.4814814814815, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081977, Length=170, Percent_Identity=30, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 62233; Mature: 62102

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYRELVFNITLITIGSILFVWALYCCGIGIDWRVFLILLAFAIILDNLGIMYTDIKLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEE
LSPTIGITTFLIFGTVGAATLMVSSVMFDTIVVRKKIKNGLLNGGMFSIAYLVAGWFYEF
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IGGKIGIVSFSQIKYILSYVIISFLLNNFILYYALKVQGKILFKEYWNESVLLELGTYIV
HCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHCCCHHHHHHHHHHH
MIPVSLLLAYIYFKHSLLFFVLSLTPLIFIAYAFRMIRDLIKANKRLNAIYEMVKMINSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LELEQILDTIIEVISQVVSVSAAAIYLTDSNGVAALVKSIGNREGEEGFKENYFKDEGII
HHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCE
GKCISSNKTIAIKDLKQDKRFLKEQFLNNYGSVVVAPLRSSGSTIGCLAVLHVDTNVFDE
EHEECCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEEECCCCCCC
DSVKIIEIIVDQASVAITNAKRYYEVTKKSITDPLTKTYNRRYFNDALMENIMRADETSE
CCCEEHHHHHHHHHHEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVSLIMFDLDNFKLINDTYGHLVGDEVLKEVAKRIKNNVRSDDIVARFGGEEFAVILPKL
CEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEEECCH
TAEQAYMIAERIRNEVLSRPIRTDKGDIYVTITGGVADYPEKADSAEKLISHADRALYAG
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
GKSKGRNKIAIYEV
CCCCCCCCEEEEEC
>Mature Secondary Structure 
GKYRELVFNITLITIGSILFVWALYCCGIGIDWRVFLILLAFAIILDNLGIMYTDIKLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEE
LSPTIGITTFLIFGTVGAATLMVSSVMFDTIVVRKKIKNGLLNGGMFSIAYLVAGWFYEF
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IGGKIGIVSFSQIKYILSYVIISFLLNNFILYYALKVQGKILFKEYWNESVLLELGTYIV
HCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHCCCHHHHHHHHHHH
MIPVSLLLAYIYFKHSLLFFVLSLTPLIFIAYAFRMIRDLIKANKRLNAIYEMVKMINSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LELEQILDTIIEVISQVVSVSAAAIYLTDSNGVAALVKSIGNREGEEGFKENYFKDEGII
HHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCE
GKCISSNKTIAIKDLKQDKRFLKEQFLNNYGSVVVAPLRSSGSTIGCLAVLHVDTNVFDE
EHEECCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEEECCCCCCC
DSVKIIEIIVDQASVAITNAKRYYEVTKKSITDPLTKTYNRRYFNDALMENIMRADETSE
CCCEEHHHHHHHHHHEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVSLIMFDLDNFKLINDTYGHLVGDEVLKEVAKRIKNNVRSDDIVARFGGEEFAVILPKL
CEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEEECCH
TAEQAYMIAERIRNEVLSRPIRTDKGDIYVTITGGVADYPEKADSAEKLISHADRALYAG
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
GKSKGRNKIAIYEV
CCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]