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The map label for this gene is ykoW [H]

Identifier: 167039430

GI number: 167039430

Start: 804745

End: 805380

Strand: Reverse

Name: ykoW [H]

Synonym: Teth514_0775

Alternate gene names: 167039430

Gene position: 805380-804745 (Counterclockwise)

Preceding gene: 167039434

Following gene: 167039420

Centisome position: 32.78

GC content: 32.08

Gene sequence:

>636_bases
TTGCTTCAAATCCTACTACTTTCCAGGTATCACGATCGCGTTCATCTATCAGGCGTATGTCTTATCAAAGAATTTGGTAT
TTTTATTATTGAAGATATTTTTAAACAAATAAAAGATTGGCGGAATAAGGGTATCGAGCTTAAGGTTAACATCAATGTTT
CTCCCCTTCAGCTTAGGGACGATGAGTTTTTCTTTAAATTTGATGAGCTTATTAGTAAATACAATATACCATCAAATCTC
ATCGGCATAGAATTTACTGAAACTCAAATATTAGATATTAAAGAGCAAAGGGTAAATAAAATAGACGAATTTTTAAGAAG
GGGAATAAAGATTTCGCTAGATGATTTTGGAGTTGGATATTCTTCCTTAATAAACATGATAGAGTTTCCTATAAGCACTA
TTAAGATGGACAAAAGCCTTATTGACAGGATTGACGAAAACAAAGTAAAAACATTAATTAAGGGAATTTTGTATATCTCA
AAGGAAATGAACTATGAAGTCGTAGCGGAAGGGGTAGAAACAGAGGAACAGCTTAGTATGCTAAAGGAATGGGGTTGTGA
CAAAATACAAGGTTATTATATATCGAGACCTAAAACTTCAAAGGAGATAGAATTAATGTTCAATTATGCTTATTAG

Upstream 100 bases:

>100_bases
TCATATAATATGCAAAGAAAATTAACAAGTTTATATAAAAAATAAAAAATGTAAATGCGCCTTTTGTAGGTAAATTCCTC
AAAAGTGCTAAGAGCTTGCT

Downstream 100 bases:

>100_bases
TGCAGTCCTTTATCTATTAAAGGACTTTAATTTATCTATTGAAAAAGGAGAGATTGTAGCACTTTTAGGTCCCAGTGGAA
GCGGTAAATGTACAATTTTA

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MLQILLLSRYHDRVHLSGVCLIKEFGIFIIEDIFKQIKDWRNKGIELKVNINVSPLQLRDDEFFFKFDELISKYNIPSNL
IGIEFTETQILDIKEQRVNKIDEFLRRGIKISLDDFGVGYSSLINMIEFPISTIKMDKSLIDRIDENKVKTLIKGILYIS
KEMNYEVVAEGVETEEQLSMLKEWGCDKIQGYYISRPKTSKEIELMFNYAY

Sequences:

>Translated_211_residues
MLQILLLSRYHDRVHLSGVCLIKEFGIFIIEDIFKQIKDWRNKGIELKVNINVSPLQLRDDEFFFKFDELISKYNIPSNL
IGIEFTETQILDIKEQRVNKIDEFLRRGIKISLDDFGVGYSSLINMIEFPISTIKMDKSLIDRIDENKVKTLIKGILYIS
KEMNYEVVAEGVETEEQLSMLKEWGCDKIQGYYISRPKTSKEIELMFNYAY
>Mature_211_residues
MLQILLLSRYHDRVHLSGVCLIKEFGIFIIEDIFKQIKDWRNKGIELKVNINVSPLQLRDDEFFFKFDELISKYNIPSNL
IGIEFTETQILDIKEQRVNKIDEFLRRGIKISLDDFGVGYSSLINMIEFPISTIKMDKSLIDRIDENKVKTLIKGILYIS
KEMNYEVVAEGVETEEQLSMLKEWGCDKIQGYYISRPKTSKEIELMFNYAY

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081921, Length=210, Percent_Identity=30.952380952381, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787541, Length=185, Percent_Identity=32.972972972973, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI226510982, Length=189, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788502, Length=155, Percent_Identity=34.8387096774194, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790496, Length=177, Percent_Identity=27.1186440677966, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1787055, Length=182, Percent_Identity=29.6703296703297, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87081743, Length=176, Percent_Identity=28.4090909090909, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI87082096, Length=152, Percent_Identity=29.6052631578947, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081845, Length=122, Percent_Identity=36.0655737704918, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788849, Length=192, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081980, Length=153, Percent_Identity=30.718954248366, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786507, Length=116, Percent_Identity=30.1724137931034, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787410, Length=153, Percent_Identity=25.4901960784314, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 24840; Mature: 24840

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQILLLSRYHDRVHLSGVCLIKEFGIFIIEDIFKQIKDWRNKGIELKVNINVSPLQLRD
CEEEEEEHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEECC
DEFFFKFDELISKYNIPSNLIGIEFTETQILDIKEQRVNKIDEFLRRGIKISLDDFGVGY
CHHHHHHHHHHHHCCCCCCEEEEEECCHHEEHHHHHHHHHHHHHHHCCCEEEECCCCCCH
SSLINMIEFPISTIKMDKSLIDRIDENKVKTLIKGILYISKEMNYEVVAEGVETEEQLSM
HHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHH
LKEWGCDKIQGYYISRPKTSKEIELMFNYAY
HHHCCCCCCCCEEECCCCCCCEEEEEEEECC
>Mature Secondary Structure
MLQILLLSRYHDRVHLSGVCLIKEFGIFIIEDIFKQIKDWRNKGIELKVNINVSPLQLRD
CEEEEEEHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEECC
DEFFFKFDELISKYNIPSNLIGIEFTETQILDIKEQRVNKIDEFLRRGIKISLDDFGVGY
CHHHHHHHHHHHHCCCCCCEEEEEECCHHEEHHHHHHHHHHHHHHHCCCEEEECCCCCCH
SSLINMIEFPISTIKMDKSLIDRIDENKVKTLIKGILYISKEMNYEVVAEGVETEEQLSM
HHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHH
LKEWGCDKIQGYYISRPKTSKEIELMFNYAY
HHHCCCCCCCCEEECCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]