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The map label for this gene is gpmA [H]

Identifier: 167039326

GI number: 167039326

Start: 701208

End: 701963

Strand: Direct

Name: gpmA [H]

Synonym: Teth514_0667

Alternate gene names: 167039326

Gene position: 701208-701963 (Clockwise)

Preceding gene: 167039324

Following gene: 167039327

Centisome position: 28.54

GC content: 38.62

Gene sequence:

>756_bases
ATGCATAAAGTTGTTTTGCTAAGACATGGAGAAAGCCTGTGGAATATGGAAAACAGATTTACTGGCTGGACGGATGTTGA
TTTATCTCCAAAGGGCATTGAAGAAGCTCGGGAAAGCGGCAAGACTTTAAAGGCAGAAGGGTACACTTTTGACTGTGCTT
TTACTTCTGTTTTAAAAAGAGCTATAAGAACTTTGTGGATTGTTCTTGACGAATTAGACAGGATGTGGATACCGGTTTAT
AAATCATGGAGGCTCAATGAAAGGCATTATGGAGCACTGCAAGGGCTTAATAAAGCTGAGACCGCCAAGAAATACGGAGA
AGAGCAGGTAAAAATATGGAGAAGATCTGCTGATGTAAGGCCTCCCGCCTTAGAAAAAGATGACCCGAGATATCCCGGTT
TTGACCCCAGATATGCTGACCTTTCTGAGGAAGAAATCCCCCTTACTGAAAATTTGATTGATACAATTAACAGAGTTATT
CCATATTGGGAGTCCACAATTGCACCGACTATAAAATCAGGTAAAAAAGTGCTAATAGTTGCTCATGGAAATAGTTTGAG
AGGGCTTGTAAAATACCTTGACAATCTTTCTAAGCAGGAGATAATGGAGTTAAATATTCCTACAGGAATTCCGTTAGTTT
ATGAGCTTGACGATGATTTAAAACCTATAAGGCATTATTATCTTGCCGATGAAGAGAAAGTAAAAGAGAAGAAAGAATTA
GTAGAAAACCAAGGAAAGATTCAAGGGAATTCTTAA

Upstream 100 bases:

>100_bases
ATACTGTTGTAATTGCTTGATAATTGAGATATAATTAAGAAAACAGGATAGAGTGGGAAAAGACAGAAAATGTTTGTAAA
TATGAAAGGTGGGGATATGT

Downstream 100 bases:

>100_bases
AATATTATCTTGTCTTATTTTTACTTGTTTTTTGGCTTCTAAAAGTGTACAATAGAAATATAAGGAATATAGAATGAGAG
GTGTATTTTGTATGTTGAGT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MHKVVLLRHGESLWNMENRFTGWTDVDLSPKGIEEARESGKTLKAEGYTFDCAFTSVLKRAIRTLWIVLDELDRMWIPVY
KSWRLNERHYGALQGLNKAETAKKYGEEQVKIWRRSADVRPPALEKDDPRYPGFDPRYADLSEEEIPLTENLIDTINRVI
PYWESTIAPTIKSGKKVLIVAHGNSLRGLVKYLDNLSKQEIMELNIPTGIPLVYELDDDLKPIRHYYLADEEKVKEKKEL
VENQGKIQGNS

Sequences:

>Translated_251_residues
MHKVVLLRHGESLWNMENRFTGWTDVDLSPKGIEEARESGKTLKAEGYTFDCAFTSVLKRAIRTLWIVLDELDRMWIPVY
KSWRLNERHYGALQGLNKAETAKKYGEEQVKIWRRSADVRPPALEKDDPRYPGFDPRYADLSEEEIPLTENLIDTINRVI
PYWESTIAPTIKSGKKVLIVAHGNSLRGLVKYLDNLSKQEIMELNIPTGIPLVYELDDDLKPIRHYYLADEEKVKEKKEL
VENQGKIQGNS
>Mature_251_residues
MHKVVLLRHGESLWNMENRFTGWTDVDLSPKGIEEARESGKTLKAEGYTFDCAFTSVLKRAIRTLWIVLDELDRMWIPVY
KSWRLNERHYGALQGLNKAETAKKYGEEQVKIWRRSADVRPPALEKDDPRYPGFDPRYADLSEEEIPLTENLIDTINRVI
PYWESTIAPTIKSGKKVLIVAHGNSLRGLVKYLDNLSKQEIMELNIPTGIPLVYELDDDLKPIRHYYLADEEKVKEKKEL
VENQGKIQGNS

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=62, Blast_Score=310, Evalue=8e-85,
Organism=Homo sapiens, GI50593010, Length=250, Percent_Identity=57.6, Blast_Score=302, Evalue=2e-82,
Organism=Homo sapiens, GI71274132, Length=248, Percent_Identity=59.6774193548387, Blast_Score=292, Evalue=2e-79,
Organism=Homo sapiens, GI4502445, Length=252, Percent_Identity=47.6190476190476, Blast_Score=257, Evalue=6e-69,
Organism=Homo sapiens, GI40353764, Length=252, Percent_Identity=47.6190476190476, Blast_Score=257, Evalue=6e-69,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=63.5802469135803, Blast_Score=206, Evalue=1e-53,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=68.6991869918699, Blast_Score=355, Evalue=2e-99,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=52.4390243902439, Blast_Score=251, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6324516, Length=292, Percent_Identity=32.5342465753425, Blast_Score=143, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320183, Length=300, Percent_Identity=32.6666666666667, Blast_Score=132, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24646216, Length=251, Percent_Identity=55.7768924302789, Blast_Score=270, Evalue=9e-73,
Organism=Drosophila melanogaster, GI85725270, Length=249, Percent_Identity=56.2248995983936, Blast_Score=260, Evalue=6e-70,
Organism=Drosophila melanogaster, GI85725272, Length=249, Percent_Identity=56.2248995983936, Blast_Score=260, Evalue=6e-70,
Organism=Drosophila melanogaster, GI24650981, Length=249, Percent_Identity=56.2248995983936, Blast_Score=260, Evalue=6e-70,
Organism=Drosophila melanogaster, GI28571817, Length=219, Percent_Identity=37.8995433789954, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28571815, Length=219, Percent_Identity=37.8995433789954, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24648979, Length=219, Percent_Identity=37.8995433789954, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 29070; Mature: 29070

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKVVLLRHGESLWNMENRFTGWTDVDLSPKGIEEARESGKTLKAEGYTFDCAFTSVLKR
CCEEEEEECCCHHHCHHHCCCCCCCCCCCCCHHHHHHHCCCEEEECCEEEHHHHHHHHHH
AIRTLWIVLDELDRMWIPVYKSWRLNERHYGALQGLNKAETAKKYGEEQVKIWRRSADVR
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHCHHHHHHHHHHCCCC
PPALEKDDPRYPGFDPRYADLSEEEIPLTENLIDTINRVIPYWESTIAPTIKSGKKVLIV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEE
AHGNSLRGLVKYLDNLSKQEIMELNIPTGIPLVYELDDDLKPIRHYYLADEEKVKEKKEL
ECCCHHHHHHHHHHCCCHHHHEEECCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHH
VENQGKIQGNS
HHHCCCCCCCC
>Mature Secondary Structure
MHKVVLLRHGESLWNMENRFTGWTDVDLSPKGIEEARESGKTLKAEGYTFDCAFTSVLKR
CCEEEEEECCCHHHCHHHCCCCCCCCCCCCCHHHHHHHCCCEEEECCEEEHHHHHHHHHH
AIRTLWIVLDELDRMWIPVYKSWRLNERHYGALQGLNKAETAKKYGEEQVKIWRRSADVR
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHCHHHHHHHHHHCCCC
PPALEKDDPRYPGFDPRYADLSEEEIPLTENLIDTINRVIPYWESTIAPTIKSGKKVLIV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEE
AHGNSLRGLVKYLDNLSKQEIMELNIPTGIPLVYELDDDLKPIRHYYLADEEKVKEKKEL
ECCCHHHHHHHHHHCCCHHHHEEECCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHH
VENQGKIQGNS
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA