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The map label for this gene is argG [H]

Identifier: 167039322

GI number: 167039322

Start: 695067

End: 696299

Strand: Direct

Name: argG [H]

Synonym: Teth514_0663

Alternate gene names: 167039322

Gene position: 695067-696299 (Clockwise)

Preceding gene: 167039321

Following gene: 167039323

Centisome position: 28.29

GC content: 39.5

Gene sequence:

>1233_bases
ATGTTAAAAGGTGAAAAAGTAGTACTTGCTTATTCAGGAGGGCTTGACACATCAGTAATCATACCGTGGCTTAAAGAAAA
CTATGAATGTGAGATAATAGCAGCTTGCATTAATGTAGGACAGGGGGAAGAGCTTAAATATATAAAAGATAAAGCTTTGG
CAAGTGGTGCCAGCAAAGTGTATATTGAAGACGTAAAAGAAGAATTTGTTAAAGATTATATATTTCCTACTTTAAAGGCT
GGTGCTGTTTACGAAGGGAAATACCTTTTAGGCACTTCTATGGCGAGGCCTTTAATTGCTAAAAAACTTGTGGAAATTGC
CCACAAAGAGGGTGCAAAGGCAATAGCTCATGGTGCAACAGGAAAAGGCAATGACCAGGTGAGGTTTGAGGTATCAATAC
ATGCTCTTGACCCGTCAATAAAAATCATAGCCCCGTGGAGGATATGGGATTTAAAATCAAGGGAAGACGAAATAGACTAT
GCCAAAAAGAAAGGGATTCCAATTCCTGTTACTAAAGAAAAAATATACAGTGTCGATAATAATTTGTGGCATGTAAGCCA
TGAAGGTGGCGACCTTGAAGACCCGTGGAATGAGCCTAAAAGTGACCTTTACGATATAATCACTCCACCTGACAAAGCCC
CAGATAAGCCAGAATATGTGCTTATAGAATTTGAAAAGGGCATACCTGTGAAAGTAAACGGCAAAGCCTTAGAACCTGTC
AAATTAATAGAAGAATTAAACGCAATTGCAGGAAGAAACGGCGTAGGAATAGCCGACCTTGTGGAAAATAGACTTGTAGG
AATGAAGTCTCGCGGTGTTTATGAAACTCCTGCAGGGACACTGCTTTACGCTGCTCATAAAGAACTTGAATATCTTGTGC
TTGATAAGGAAACAATGAGGTTTAAGGATTTGGTTTCGCAGAAATATGCAGACCTTGTTTACAACGGTTTGTGGTTTTCA
CCACTTAAAGCCGCGCTAGACGCTTTTGTGGAGGAAACGCAAAAAAATGTAACGGGTGTTGTAAGGCTAAAGCTTTATAA
AGGAAATGTCATAAACGCAGGAGTAAAATCCCCTTATTCTCTCTATAATCAGGAATTTGTTACTTTTGGCAAAGACGAAG
TCTACAACCAAAAAGACGCAGAAGGATTTATAAACCTCTTTGGGCTTTCTTTAAAAATTAAGGCGTTGATGGAAATGGAG
AGGAAGGATATGGATGAAGCTGTGGGGAGGTAG

Upstream 100 bases:

>100_bases
AAAGTAAATGTGAATGGTTTGTCTATTTTATCTATAAACGAATATGAAGAAATACAAAAAGATAATGTCAAAAATTTGGT
TTTGTAAGGAGTGTTTAAAA

Downstream 100 bases:

>100_bases
GTTTAAAAGCGAGACGGACAAACTAATGGAGGAGTTTAATTCCTCCATTTCTTTTGATATTAGGCTTTTAAAGCATGACA
TATTAGGCTCAATTGCCCAT

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLKGEKVVLAYSGGLDTSVIIPWLKENYECEIIAACINVGQGEELKYIKDKALASGASKVYIEDVKEEFVKDYIFPTLKA
GAVYEGKYLLGTSMARPLIAKKLVEIAHKEGAKAIAHGATGKGNDQVRFEVSIHALDPSIKIIAPWRIWDLKSREDEIDY
AKKKGIPIPVTKEKIYSVDNNLWHVSHEGGDLEDPWNEPKSDLYDIITPPDKAPDKPEYVLIEFEKGIPVKVNGKALEPV
KLIEELNAIAGRNGVGIADLVENRLVGMKSRGVYETPAGTLLYAAHKELEYLVLDKETMRFKDLVSQKYADLVYNGLWFS
PLKAALDAFVEETQKNVTGVVRLKLYKGNVINAGVKSPYSLYNQEFVTFGKDEVYNQKDAEGFINLFGLSLKIKALMEME
RKDMDEAVGR

Sequences:

>Translated_410_residues
MLKGEKVVLAYSGGLDTSVIIPWLKENYECEIIAACINVGQGEELKYIKDKALASGASKVYIEDVKEEFVKDYIFPTLKA
GAVYEGKYLLGTSMARPLIAKKLVEIAHKEGAKAIAHGATGKGNDQVRFEVSIHALDPSIKIIAPWRIWDLKSREDEIDY
AKKKGIPIPVTKEKIYSVDNNLWHVSHEGGDLEDPWNEPKSDLYDIITPPDKAPDKPEYVLIEFEKGIPVKVNGKALEPV
KLIEELNAIAGRNGVGIADLVENRLVGMKSRGVYETPAGTLLYAAHKELEYLVLDKETMRFKDLVSQKYADLVYNGLWFS
PLKAALDAFVEETQKNVTGVVRLKLYKGNVINAGVKSPYSLYNQEFVTFGKDEVYNQKDAEGFINLFGLSLKIKALMEME
RKDMDEAVGR
>Mature_410_residues
MLKGEKVVLAYSGGLDTSVIIPWLKENYECEIIAACINVGQGEELKYIKDKALASGASKVYIEDVKEEFVKDYIFPTLKA
GAVYEGKYLLGTSMARPLIAKKLVEIAHKEGAKAIAHGATGKGNDQVRFEVSIHALDPSIKIIAPWRIWDLKSREDEIDY
AKKKGIPIPVTKEKIYSVDNNLWHVSHEGGDLEDPWNEPKSDLYDIITPPDKAPDKPEYVLIEFEKGIPVKVNGKALEPV
KLIEELNAIAGRNGVGIADLVENRLVGMKSRGVYETPAGTLLYAAHKELEYLVLDKETMRFKDLVSQKYADLVYNGLWFS
PLKAALDAFVEETQKNVTGVVRLKLYKGNVINAGVKSPYSLYNQEFVTFGKDEVYNQKDAEGFINLFGLSLKIKALMEME
RKDMDEAVGR

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=395, Percent_Identity=49.620253164557, Blast_Score=370, Evalue=1e-103,
Organism=Homo sapiens, GI16950633, Length=395, Percent_Identity=49.620253164557, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1789563, Length=411, Percent_Identity=29.4403892944039, Blast_Score=152, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6324514, Length=408, Percent_Identity=43.6274509803922, Blast_Score=323, Evalue=4e-89,
Organism=Drosophila melanogaster, GI21358151, Length=401, Percent_Identity=43.142144638404, Blast_Score=331, Evalue=5e-91,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 45806; Mature: 45806

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGEKVVLAYSGGLDTSVIIPWLKENYECEIIAACINVGQGEELKYIKDKALASGASKV
CCCCCEEEEEECCCCCCEEEEEHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEE
YIEDVKEEFVKDYIFPTLKAGAVYEGKYLLGTSMARPLIAKKLVEIAHKEGAKAIAHGAT
HHHHHHHHHHHHHHCCCCCCCEEECCCEEECHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
GKGNDQVRFEVSIHALDPSIKIIAPWRIWDLKSREDEIDYAKKKGIPIPVTKEKIYSVDN
CCCCCEEEEEEEEEEECCCEEEEEEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHCCCC
NLWHVSHEGGDLEDPWNEPKSDLYDIITPPDKAPDKPEYVLIEFEKGIPVKVNGKALEPV
CEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCHH
KLIEELNAIAGRNGVGIADLVENRLVGMKSRGVYETPAGTLLYAAHKELEYLVLDKETMR
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEECCCCEEEEEECCCCEEEEECCHHHH
FKDLVSQKYADLVYNGLWFSPLKAALDAFVEETQKNVTGVVRLKLYKGNVINAGVKSPYS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEECCCCCCHH
LYNQEFVTFGKDEVYNQKDAEGFINLFGLSLKIKALMEMERKDMDEAVGR
HHCCHHEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKGEKVVLAYSGGLDTSVIIPWLKENYECEIIAACINVGQGEELKYIKDKALASGASKV
CCCCCEEEEEECCCCCCEEEEEHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEE
YIEDVKEEFVKDYIFPTLKAGAVYEGKYLLGTSMARPLIAKKLVEIAHKEGAKAIAHGAT
HHHHHHHHHHHHHHCCCCCCCEEECCCEEECHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
GKGNDQVRFEVSIHALDPSIKIIAPWRIWDLKSREDEIDYAKKKGIPIPVTKEKIYSVDN
CCCCCEEEEEEEEEEECCCEEEEEEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHCCCC
NLWHVSHEGGDLEDPWNEPKSDLYDIITPPDKAPDKPEYVLIEFEKGIPVKVNGKALEPV
CEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCHH
KLIEELNAIAGRNGVGIADLVENRLVGMKSRGVYETPAGTLLYAAHKELEYLVLDKETMR
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEECCCCEEEEEECCCCEEEEECCHHHH
FKDLVSQKYADLVYNGLWFSPLKAALDAFVEETQKNVTGVVRLKLYKGNVINAGVKSPYS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEECCCCCCHH
LYNQEFVTFGKDEVYNQKDAEGFINLFGLSLKIKALMEMERKDMDEAVGR
HHCCHHEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA