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The map label for this gene is nasD [H]

Identifier: 167039220

GI number: 167039220

Start: 584153

End: 585421

Strand: Direct

Name: nasD [H]

Synonym: Teth514_0561

Alternate gene names: 167039220

Gene position: 584153-585421 (Clockwise)

Preceding gene: 167039219

Following gene: 167039221

Centisome position: 23.77

GC content: 33.25

Gene sequence:

>1269_bases
ATGAGGATAGTAATAATTGGTAATTCTGTTGCGATGGTAGGTGCAGTAGAGGCAATAAGAAAATATGATACAAGTTCTGA
AATAGTTGTTATTTCAGATGAAACATATCACGTGTATTCAAGACCCCTTATATCTTATTATCTTGGAAATTTAGTGTCTG
AAGAGAAAATGATATATAGAGAGAAAGATTTTTACCGCAAAAATAAAGTAGAAACTGTATTTGGTATTAAGGCTATTTCT
ATTGATGAAAGAAAAAAAGAAGTGCATCTTGAAAACGGGGATAGCATAAGTTTTGACAAACTTCTCATTGCAACGGGCGG
GAAACCTATAATACCTCCAGTAGAAGGTTTGAACAAAAAAAATGTTCATACTTTTATTAAAATGGACGACGCTAAAAAAT
TAAAGGAAGCTGCCAAGCCGGGTTCAAAAGCTGTAATTGTAGGTGGTGGTCTCATCGGTTTCAAAGCAGCAGAAGGCCTT
CACCATTTAGGGGTAGATGTAACAATAGTTGAACTTGCAGATAGGATTTTAAGTACAATTCTTGATGCAGAAGGAGCATC
TTTGGTATCTCAAAGTCTTCAAAATGACGGTATAAAAATAATTACGGGAACAACAGTGGATAAAATTATAGGAGACGAAT
ATGTTAAGGGAGTTTTGCTTAAAAATGGGAAGGAATTAGAAGCTGACAATCTTATTATCGCGATAGGTGTTGTGCCAAAC
GTTGATGTTGTAAGAAACACATCAATTTCTATAAACCGTGGTATTTTAGTAGATAATACTATGAAAACAAGCGTTGAAGA
TGTGTATGCAGCAGGAGATGTAGCCGAAGGGTATGATATGCTTGTTGAGTCAAATAGGGTTGTGCCAATATGGCCAAATG
CATACATGCAAGGGGAAATTGCAGGGTACAACATGATTGGTATAAATAAAAGTTTTAAAGGGATTTTTCCTATGAACTCA
ATAGGTTATAAAAATACAAATATGATAACAGCTGGTATAACAAATCCACAGCAGGAGGAATTTGAGATTATCTCTAAAAT
TGATCATAACAGAAGGTCTTATAAAAAATTTGTGGTAAAAGAAAATAGATTAGTAGGATTTATATTAATTAATGATATTG
ATAGGGCTGGATTATTTACTGGATTTATAAAAAATGAAACGGATATAACTCCATTTAAGAAATATCTTTTAAATGATGAT
TTTGGATTTATATATTTGCCAAAAGAATTAAGAAAGGCAAAAATGCTTGACCTGGAGGTGGTACGATGA

Upstream 100 bases:

>100_bases
TTGCATCAAAATGTGACTTATGTGCTGAAGCAGGAGAACCGGCTTGTGTCAAGAATTGTCCTAATGAGGCACTTGTCTAT
AGTGAAGGAGGCATTTCTGT

Downstream 100 bases:

>100_bases
AAACCATAAATGCGTCAGGAATTTATTATAGAGACCTTAATGAAATAATTAAAGAGTTAGTTCGTTCAGGTGAAGACATA
ATTAATTTAAAAAATGTCAA

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MRIVIIGNSVAMVGAVEAIRKYDTSSEIVVISDETYHVYSRPLISYYLGNLVSEEKMIYREKDFYRKNKVETVFGIKAIS
IDERKKEVHLENGDSISFDKLLIATGGKPIIPPVEGLNKKNVHTFIKMDDAKKLKEAAKPGSKAVIVGGGLIGFKAAEGL
HHLGVDVTIVELADRILSTILDAEGASLVSQSLQNDGIKIITGTTVDKIIGDEYVKGVLLKNGKELEADNLIIAIGVVPN
VDVVRNTSISINRGILVDNTMKTSVEDVYAAGDVAEGYDMLVESNRVVPIWPNAYMQGEIAGYNMIGINKSFKGIFPMNS
IGYKNTNMITAGITNPQQEEFEIISKIDHNRRSYKKFVVKENRLVGFILINDIDRAGLFTGFIKNETDITPFKKYLLNDD
FGFIYLPKELRKAKMLDLEVVR

Sequences:

>Translated_422_residues
MRIVIIGNSVAMVGAVEAIRKYDTSSEIVVISDETYHVYSRPLISYYLGNLVSEEKMIYREKDFYRKNKVETVFGIKAIS
IDERKKEVHLENGDSISFDKLLIATGGKPIIPPVEGLNKKNVHTFIKMDDAKKLKEAAKPGSKAVIVGGGLIGFKAAEGL
HHLGVDVTIVELADRILSTILDAEGASLVSQSLQNDGIKIITGTTVDKIIGDEYVKGVLLKNGKELEADNLIIAIGVVPN
VDVVRNTSISINRGILVDNTMKTSVEDVYAAGDVAEGYDMLVESNRVVPIWPNAYMQGEIAGYNMIGINKSFKGIFPMNS
IGYKNTNMITAGITNPQQEEFEIISKIDHNRRSYKKFVVKENRLVGFILINDIDRAGLFTGFIKNETDITPFKKYLLNDD
FGFIYLPKELRKAKMLDLEVVR
>Mature_422_residues
MRIVIIGNSVAMVGAVEAIRKYDTSSEIVVISDETYHVYSRPLISYYLGNLVSEEKMIYREKDFYRKNKVETVFGIKAIS
IDERKKEVHLENGDSISFDKLLIATGGKPIIPPVEGLNKKNVHTFIKMDDAKKLKEAAKPGSKAVIVGGGLIGFKAAEGL
HHLGVDVTIVELADRILSTILDAEGASLVSQSLQNDGIKIITGTTVDKIIGDEYVKGVLLKNGKELEADNLIIAIGVVPN
VDVVRNTSISINRGILVDNTMKTSVEDVYAAGDVAEGYDMLVESNRVVPIWPNAYMQGEIAGYNMIGINKSFKGIFPMNS
IGYKNTNMITAGITNPQQEEFEIISKIDHNRRSYKKFVVKENRLVGFILINDIDRAGLFTGFIKNETDITPFKKYLLNDD
FGFIYLPKELRKAKMLDLEVVR

Specific function: Required for nitrite assimilation [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=332, Percent_Identity=29.2168674698795, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI226437568, Length=332, Percent_Identity=29.2168674698795, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI65787454, Length=332, Percent_Identity=29.2168674698795, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI4757732, Length=330, Percent_Identity=24.5454545454545, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI22202629, Length=330, Percent_Identity=24.5454545454545, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1789765, Length=399, Percent_Identity=25.5639097744361, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789065, Length=370, Percent_Identity=24.3243243243243, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788892, Length=277, Percent_Identity=27.0758122743682, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082354, Length=283, Percent_Identity=28.6219081272085, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559934, Length=310, Percent_Identity=28.0645161290323, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32564386, Length=340, Percent_Identity=27.3529411764706, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639257, Length=318, Percent_Identity=27.9874213836478, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI281359715, Length=318, Percent_Identity=27.9874213836478, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI281359713, Length=318, Percent_Identity=27.9874213836478, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24639250, Length=318, Percent_Identity=27.9874213836478, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI18543267, Length=318, Percent_Identity=27.9874213836478, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24639252, Length=318, Percent_Identity=27.9874213836478, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24581020, Length=349, Percent_Identity=25.7879656160458, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573993, Length=349, Percent_Identity=25.7879656160458, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585130, Length=311, Percent_Identity=24.4372990353698, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585384, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR013027
- InterPro:   IPR005117
- InterPro:   IPR012744
- InterPro:   IPR017121
- InterPro:   IPR006067
- InterPro:   IPR006066
- InterPro:   IPR001327 [H]

Pfam domain/function: PF04324 Fer2_BFD; PF01077 NIR_SIR; PF03460 NIR_SIR_ferr; PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.7.1.4 [H]

Molecular weight: Translated: 46829; Mature: 46829

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVIIGNSVAMVGAVEAIRKYDTSSEIVVISDETYHVYSRPLISYYLGNLVSEEKMIYR
CEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCEEEEHHCHHHHHHHHHHHCHHHHHHH
EKDFYRKNKVETVFGIKAISIDERKKEVHLENGDSISFDKLLIATGGKPIIPPVEGLNKK
HHHHHHHCCCCEEEEEEEEEECCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCC
NVHTFIKMDDAKKLKEAAKPGSKAVIVGGGLIGFKAAEGLHHLGVDVTIVELADRILSTI
CCEEEEEECCHHHHHHHHCCCCCEEEEECCEEEHHHHCCHHHCCCCEEHHHHHHHHHHHH
LDAEGASLVSQSLQNDGIKIITGTTVDKIIGDEYVKGVLLKNGKELEADNLIIAIGVVPN
HCCCCHHHHHHHHHCCCEEEEECCCHHHHHCHHHHHHHEECCCCEECCCCEEEEEECCCC
VDVVRNTSISINRGILVDNTMKTSVEDVYAAGDVAEGYDMLVESNRVVPIWPNAYMQGEI
CCEEECCEEEEECCEEEECCHHHHHHHHHHCCCCCCCHHHHCCCCCEEEECCCCEECCEE
AGYNMIGINKSFKGIFPMNSIGYKNTNMITAGITNPQQEEFEIISKIDHNRRSYKKFVVK
CCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHHHHEEE
ENRLVGFILINDIDRAGLFTGFIKNETDITPFKKYLLNDDFGFIYLPKELRKAKMLDLEV
CCCEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEECHHHHHHHCCEEEE
VR
CC
>Mature Secondary Structure
MRIVIIGNSVAMVGAVEAIRKYDTSSEIVVISDETYHVYSRPLISYYLGNLVSEEKMIYR
CEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCEEEEHHCHHHHHHHHHHHCHHHHHHH
EKDFYRKNKVETVFGIKAISIDERKKEVHLENGDSISFDKLLIATGGKPIIPPVEGLNKK
HHHHHHHCCCCEEEEEEEEEECCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCC
NVHTFIKMDDAKKLKEAAKPGSKAVIVGGGLIGFKAAEGLHHLGVDVTIVELADRILSTI
CCEEEEEECCHHHHHHHHCCCCCEEEEECCEEEHHHHCCHHHCCCCEEHHHHHHHHHHHH
LDAEGASLVSQSLQNDGIKIITGTTVDKIIGDEYVKGVLLKNGKELEADNLIIAIGVVPN
HCCCCHHHHHHHHHCCCEEEEECCCHHHHHCHHHHHHHEECCCCEECCCCEEEEEECCCC
VDVVRNTSISINRGILVDNTMKTSVEDVYAAGDVAEGYDMLVESNRVVPIWPNAYMQGEI
CCEEECCEEEEECCEEEECCHHHHHHHHHHCCCCCCCHHHHCCCCCEEEECCCCEECCEE
AGYNMIGINKSFKGIFPMNSIGYKNTNMITAGITNPQQEEFEIISKIDHNRRSYKKFVVK
CCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHHHHEEE
ENRLVGFILINDIDRAGLFTGFIKNETDITPFKKYLLNDDFGFIYLPKELRKAKMLDLEV
CCCEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEECHHHHHHHCCEEEE
VR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7868621; 8969502; 9384377 [H]