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The map label for this gene is yicO [C]

Identifier: 167039175

GI number: 167039175

Start: 531918

End: 533300

Strand: Direct

Name: yicO [C]

Synonym: Teth514_0516

Alternate gene names: 167039175

Gene position: 531918-533300 (Clockwise)

Preceding gene: 167039174

Following gene: 167039176

Centisome position: 21.65

GC content: 34.85

Gene sequence:

>1383_bases
ATGGAAAAGGTGAGTAAAGTGAGGAACAAAAATTCTTTAGAAAATCTAGCAAATAGGATATGGAGATTAGAAAACTATAA
TACCAATGTAAAAACAGAGATATTAGCTGGGATTACCACATTTATAACAATGGCTTATATTATGTTTGTGAATCCCATTA
TACTAAAAGAAGCAGGGATGGACGCAGGAGCGGTATTTGTAGCTACTTGTCTTTCAGCAGCTATTGGAACTTTCATGATG
GCTTTTTATGCTAATTACCCATTTGCACAGGCTCCAGGTATGGGACTTAACGCTTTTTTTACCTATACTGTTGTTTTGAC
AATGGGTTATACCTGGCAACAGGCTTTGGCTGCAGTTTTCTTTTCAGGAATTATATTTATTTTGATTACTTTGTTTGGAA
TACGGGAAATGATTGTTGATGCTATACCTATGTCTTTAAAATATGCAGTAAGTGGAGGAATAGGTTTATTTATAGCTTTT
ATTGGACTTAAAAATGCTGGTATAATCGTGGCAAATCAAGCAACTTACATTGGATTTGGTGATTTGACTAATCCTGGGAC
ACTTCTTGCCATTGCGGGTCTTTTTATAACAGCCATATTAATGTCGAGAAATATCAAAGGATCTATACTTCTTGGAATAT
TAATTACTACAGTATTGGGACTTTTTACTGGAATAGTGAAATTACCTTCTGATTTTAGTGTAATTAAAATGCCACCAAGT
CTTGCACCAACATTTCTTAAACTTGATATAAAAGGGCTTTTGGGAATTGGTGAGAATATTGGCTTTATTTCTTTAGTTAC
AAGTGTGCTATATGTAGTGTTGTCGTTTGCTTTTGTAGATTTATTTGATACCATAGGGACCTTTATAGGAACAGGATCAA
AAGCAGGAATGTTAGATGAAAATGGCAAAATGCCTAATATGAAAAAAGGACTAATGTCGGATGCTATTGCCACCACGATA
GGGTCACTTTTAGGAACTTCTACTGTGACTACTTACGTTGAGAGTGCTGCAGGTATTGCAGAAGGTGGTAGAACGGGACT
TACTGCTTTTGTGACAGGTATTTTGTTCTTGGTAGCATTGTTTTTCTCACCAATAGCTTTACTTGTTCCTACAGAGGCAA
CTGCTCCTGCTCTTATTATTGTTGGAGTTTTGATGATGGGTTCTATTAAGAAGATAAATTTTGAAGATTTTACAGAGGCT
ATGCCAGCTTTTCTTACTATAATTGCTATGCCTTTCACTTTTAGCATTGCCAATGGTATTGCTGCAGGTCTTATTGCATA
TCCTATTGTAAAAATTGCTTCAGGAAAAGCAAAAGAAATTCATCCAATGGTTTATTTTCTTGCAATTTTATTCATATTGA
GATTTATAACTTTATCAGAGTGA

Upstream 100 bases:

>100_bases
GGTTTCACTCGTGTTTAATTTGTGAAATCTATTCTTTGCGGGCTTATTTGTTTTAAATTCTTGTAGAAGTTGCAAAATAA
TATAGAACAGGAGGATTATG

Downstream 100 bases:

>100_bases
AAATAAGACCCCAATTAGTACTTATCTAATTGGGGTCTTAAAAGAAAAGGGGGTATAAAAATGCCTAAGGTGGCTATAGT
TGTTGGAAGTAAATCTGATT

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MEKVSKVRNKNSLENLANRIWRLENYNTNVKTEILAGITTFITMAYIMFVNPIILKEAGMDAGAVFVATCLSAAIGTFMM
AFYANYPFAQAPGMGLNAFFTYTVVLTMGYTWQQALAAVFFSGIIFILITLFGIREMIVDAIPMSLKYAVSGGIGLFIAF
IGLKNAGIIVANQATYIGFGDLTNPGTLLAIAGLFITAILMSRNIKGSILLGILITTVLGLFTGIVKLPSDFSVIKMPPS
LAPTFLKLDIKGLLGIGENIGFISLVTSVLYVVLSFAFVDLFDTIGTFIGTGSKAGMLDENGKMPNMKKGLMSDAIATTI
GSLLGTSTVTTYVESAAGIAEGGRTGLTAFVTGILFLVALFFSPIALLVPTEATAPALIIVGVLMMGSIKKINFEDFTEA
MPAFLTIIAMPFTFSIANGIAAGLIAYPIVKIASGKAKEIHPMVYFLAILFILRFITLSE

Sequences:

>Translated_460_residues
MEKVSKVRNKNSLENLANRIWRLENYNTNVKTEILAGITTFITMAYIMFVNPIILKEAGMDAGAVFVATCLSAAIGTFMM
AFYANYPFAQAPGMGLNAFFTYTVVLTMGYTWQQALAAVFFSGIIFILITLFGIREMIVDAIPMSLKYAVSGGIGLFIAF
IGLKNAGIIVANQATYIGFGDLTNPGTLLAIAGLFITAILMSRNIKGSILLGILITTVLGLFTGIVKLPSDFSVIKMPPS
LAPTFLKLDIKGLLGIGENIGFISLVTSVLYVVLSFAFVDLFDTIGTFIGTGSKAGMLDENGKMPNMKKGLMSDAIATTI
GSLLGTSTVTTYVESAAGIAEGGRTGLTAFVTGILFLVALFFSPIALLVPTEATAPALIIVGVLMMGSIKKINFEDFTEA
MPAFLTIIAMPFTFSIANGIAAGLIAYPIVKIASGKAKEIHPMVYFLAILFILRFITLSE
>Mature_460_residues
MEKVSKVRNKNSLENLANRIWRLENYNTNVKTEILAGITTFITMAYIMFVNPIILKEAGMDAGAVFVATCLSAAIGTFMM
AFYANYPFAQAPGMGLNAFFTYTVVLTMGYTWQQALAAVFFSGIIFILITLFGIREMIVDAIPMSLKYAVSGGIGLFIAF
IGLKNAGIIVANQATYIGFGDLTNPGTLLAIAGLFITAILMSRNIKGSILLGILITTVLGLFTGIVKLPSDFSVIKMPPS
LAPTFLKLDIKGLLGIGENIGFISLVTSVLYVVLSFAFVDLFDTIGTFIGTGSKAGMLDENGKMPNMKKGLMSDAIATTI
GSLLGTSTVTTYVESAAGIAEGGRTGLTAFVTGILFLVALFFSPIALLVPTEATAPALIIVGVLMMGSIKKINFEDFTEA
MPAFLTIIAMPFTFSIANGIAAGLIAYPIVKIASGKAKEIHPMVYFLAILFILRFITLSE

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=454, Percent_Identity=44.9339207048458, Blast_Score=400, Evalue=1e-112,
Organism=Escherichia coli, GI1790150, Length=448, Percent_Identity=46.6517857142857, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1790499, Length=437, Percent_Identity=34.0961098398169, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI48994909, Length=443, Percent_Identity=32.9571106094808, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 49040; Mature: 49040

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVSKVRNKNSLENLANRIWRLENYNTNVKTEILAGITTFITMAYIMFVNPIILKEAGM
CCHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAGAVFVATCLSAAIGTFMMAFYANYPFAQAPGMGLNAFFTYTVVLTMGYTWQQALAAVF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
FSGIIFILITLFGIREMIVDAIPMSLKYAVSGGIGLFIAFIGLKNAGIIVANQATYIGFG
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHCCCCCEEEECCEEEEECC
DLTNPGTLLAIAGLFITAILMSRNIKGSILLGILITTVLGLFTGIVKLPSDFSVIKMPPS
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
LAPTFLKLDIKGLLGIGENIGFISLVTSVLYVVLSFAFVDLFDTIGTFIGTGSKAGMLDE
CCCHHHHEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NGKMPNMKKGLMSDAIATTIGSLLGTSTVTTYVESAAGIAEGGRTGLTAFVTGILFLVAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FFSPIALLVPTEATAPALIIVGVLMMGSIKKINFEDFTEAMPAFLTIIAMPFTFSIANGI
HHCCHHEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGLIAYPIVKIASGKAKEIHPMVYFLAILFILRFITLSE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKVSKVRNKNSLENLANRIWRLENYNTNVKTEILAGITTFITMAYIMFVNPIILKEAGM
CCHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAGAVFVATCLSAAIGTFMMAFYANYPFAQAPGMGLNAFFTYTVVLTMGYTWQQALAAVF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
FSGIIFILITLFGIREMIVDAIPMSLKYAVSGGIGLFIAFIGLKNAGIIVANQATYIGFG
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHCCCCCEEEECCEEEEECC
DLTNPGTLLAIAGLFITAILMSRNIKGSILLGILITTVLGLFTGIVKLPSDFSVIKMPPS
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
LAPTFLKLDIKGLLGIGENIGFISLVTSVLYVVLSFAFVDLFDTIGTFIGTGSKAGMLDE
CCCHHHHEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NGKMPNMKKGLMSDAIATTIGSLLGTSTVTTYVESAAGIAEGGRTGLTAFVTGILFLVAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FFSPIALLVPTEATAPALIIVGVLMMGSIKKINFEDFTEAMPAFLTIIAMPFTFSIANGI
HHCCHHEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGLIAYPIVKIASGKAKEIHPMVYFLAILFILRFITLSE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]