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The map label for this gene is comF [H]

Identifier: 167039108

GI number: 167039108

Start: 463147

End: 463836

Strand: Direct

Name: comF [H]

Synonym: Teth514_0447

Alternate gene names: 167039108

Gene position: 463147-463836 (Clockwise)

Preceding gene: 167039107

Following gene: 167039109

Centisome position: 18.85

GC content: 34.2

Gene sequence:

>690_bases
ATGATTTTTTTAGACCTTTTATTTCCACCAAAAACAACCTGCATTATTTGTAAAACTGTTATAAAAACAGGGTATTTATG
CGACAAATGCAAAAGCACATTAAAATTTATTGAGGGTAATAGGTGTAGTATTTGTGGTAAACCAATAGACTATGAAGGAA
CATGTCCTGATTGTTTAGAACATGGTCATGAATTTAAACAAAATATAAGTCCTTTTGAATACGATGGTGTTGTAAAAGAC
TTAATAGGGCGGTTCAAATATTTCAAAGAGAGAGAATTGGCACCTTTTTTTGCAGACTATATGGCTGATGCAGTTAAAAA
AATGAACTGGCCTATAGATGTCATAGTACCTGTTCCTCTTCACAAAATTAGACTTGACGAAAGAGGTTACAATCAGTCAG
AACTTTTAGCAAGAGAACTTTCTTATCGATTGAATATTTTTATGTCTAAAGCTTTAAGAAGAGTGAGAAATACAACAACC
CAGACTGCTTTGCACAAAGAAGAGAGGATAGAAAACGTAAAGGGTGCTTTTAAAGTGACTTACAAAGATACTATTGTTGG
GAAAAATGTGTTACTGGTAGACGACGTGTTGACAACAGGTGCTACTTTGGACGAGTGTGCCAAAGTCTTAAAAGAAAATG
GGGCAAAAGATGTATATGTGGCTACCATAGCAACGGGTAAAAATATGTAA

Upstream 100 bases:

>100_bases
GAAAATTTACTGTAAAATGATAATTTTTTAATTAATTTTAATTTAATAATGCCGATATAAAATATAAAAGAAAAGTGAAT
TGCAATAAGGGGCAATAAAG

Downstream 100 bases:

>100_bases
TGGGGTGTTTGAAGTATCAAAAAGGGGGATGAAAGGAAATGGAAATAAGAAATTGTAAAAGGTGCGGAAGGCTTTACACG
TACACAGGAATTGACCTATG

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MIFLDLLFPPKTTCIICKTVIKTGYLCDKCKSTLKFIEGNRCSICGKPIDYEGTCPDCLEHGHEFKQNISPFEYDGVVKD
LIGRFKYFKERELAPFFADYMADAVKKMNWPIDVIVPVPLHKIRLDERGYNQSELLARELSYRLNIFMSKALRRVRNTTT
QTALHKEERIENVKGAFKVTYKDTIVGKNVLLVDDVLTTGATLDECAKVLKENGAKDVYVATIATGKNM

Sequences:

>Translated_229_residues
MIFLDLLFPPKTTCIICKTVIKTGYLCDKCKSTLKFIEGNRCSICGKPIDYEGTCPDCLEHGHEFKQNISPFEYDGVVKD
LIGRFKYFKERELAPFFADYMADAVKKMNWPIDVIVPVPLHKIRLDERGYNQSELLARELSYRLNIFMSKALRRVRNTTT
QTALHKEERIENVKGAFKVTYKDTIVGKNVLLVDDVLTTGATLDECAKVLKENGAKDVYVATIATGKNM
>Mature_229_residues
MIFLDLLFPPKTTCIICKTVIKTGYLCDKCKSTLKFIEGNRCSICGKPIDYEGTCPDCLEHGHEFKQNISPFEYDGVVKD
LIGRFKYFKERELAPFFADYMADAVKKMNWPIDVIVPVPLHKIRLDERGYNQSELLARELSYRLNIFMSKALRRVRNTTT
QTALHKEERIENVKGAFKVTYKDTIVGKNVLLVDDVLTTGATLDECAKVLKENGAKDVYVATIATGKNM

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=217, Percent_Identity=30.8755760368664, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 26061; Mature: 26061

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLDLLFPPKTTCIICKTVIKTGYLCDKCKSTLKFIEGNRCSICGKPIDYEGTCPDCLE
CEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHH
HGHEFKQNISPFEYDGVVKDLIGRFKYFKERELAPFFADYMADAVKKMNWPIDVIVPVPL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCH
HKIRLDERGYNQSELLARELSYRLNIFMSKALRRVRNTTTQTALHKEERIENVKGAFKVT
HEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
YKDTIVGKNVLLVDDVLTTGATLDECAKVLKENGAKDVYVATIATGKNM
EHHHHCCCCEEEEHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MIFLDLLFPPKTTCIICKTVIKTGYLCDKCKSTLKFIEGNRCSICGKPIDYEGTCPDCLE
CEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHH
HGHEFKQNISPFEYDGVVKDLIGRFKYFKERELAPFFADYMADAVKKMNWPIDVIVPVPL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCH
HKIRLDERGYNQSELLARELSYRLNIFMSKALRRVRNTTTQTALHKEERIENVKGAFKVT
HEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
YKDTIVGKNVLLVDDVLTTGATLDECAKVLKENGAKDVYVATIATGKNM
EHHHHCCCCEEEEHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]