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The map label for this gene is yycF [H]

Identifier: 167039100

GI number: 167039100

Start: 453299

End: 453976

Strand: Direct

Name: yycF [H]

Synonym: Teth514_0439

Alternate gene names: 167039100

Gene position: 453299-453976 (Clockwise)

Preceding gene: 167039099

Following gene: 167039101

Centisome position: 18.45

GC content: 34.51

Gene sequence:

>678_bases
ATGGAAAAATTGTTAATTATAGATGATGAAGAGATGTTTGTAAAAGGGTTAAAACTTTCTTTAGAAGAAGAAGGATTTGA
AGTTGACGCCGCTTACGATGGGGAAGAAGGGCTTGACAAAGTTCGTTTAGGGAATTATGACCTTGTAATTTTAGATATTA
TGCTTCCTAAGTTAGACGGTTTTTCGGTATGTAGAGAGATAAGGACTTTTTCAAATATTCCCATAATTATGCTTACTGCA
AGAGGAGACGATATTGACAAGATTGTAGGGATAGAAATAGGAGCTGATGATTATTTAGCGAAGCCCTTTAATACTAGAGA
GCTTACTGCGCGAATAAGAGCACTTTTAAGAAGAGCTACAAATCCTTATACTAAGCGGAAAGATGAAATAAGAAGGGGAG
AACTTTATATAAATATTCCCGAAAGAGCAGTTTACAAGAGAGGGAAGAGAATTGAGCTTACAAATAAAGAATTTGAAATT
TTAGTGTTGTTAGCTTCTAATCCAGGAAAAGTCTATACGAAAGATAAATTGTTAGACTTGATATGGGGATTTGATTTTTA
CGGTGATACAAATACTGTTACAGTGCATGTGAGAAAACTTAGGGAGAAAATTGAAGATGACCCTGCAAATCCTCAATATA
TTTTCACCAAATGGGGTGCAGGATACTATATGAAGTAA

Upstream 100 bases:

>100_bases
TGTAAGAGAATCTACTGGCTTTGGAGAAGAAAAAAATAGCCGATAAGGCTATTTTTTTTATAAATTGTTGTGGTATACTG
GTGTCAGGAGGGAGGTATAT

Downstream 100 bases:

>100_bases
AGGTGATAAAATGAGTTTAAGGTGGAAAATCTTTTCTTTATATTTAATAATTTTAATAATTTCATTGGCATTAACTGGGC
TTTATCTTTACCGTTATATT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MEKLLIIDDEEMFVKGLKLSLEEEGFEVDAAYDGEEGLDKVRLGNYDLVILDIMLPKLDGFSVCREIRTFSNIPIIMLTA
RGDDIDKIVGIEIGADDYLAKPFNTRELTARIRALLRRATNPYTKRKDEIRRGELYINIPERAVYKRGKRIELTNKEFEI
LVLLASNPGKVYTKDKLLDLIWGFDFYGDTNTVTVHVRKLREKIEDDPANPQYIFTKWGAGYYMK

Sequences:

>Translated_225_residues
MEKLLIIDDEEMFVKGLKLSLEEEGFEVDAAYDGEEGLDKVRLGNYDLVILDIMLPKLDGFSVCREIRTFSNIPIIMLTA
RGDDIDKIVGIEIGADDYLAKPFNTRELTARIRALLRRATNPYTKRKDEIRRGELYINIPERAVYKRGKRIELTNKEFEI
LVLLASNPGKVYTKDKLLDLIWGFDFYGDTNTVTVHVRKLREKIEDDPANPQYIFTKWGAGYYMK
>Mature_225_residues
MEKLLIIDDEEMFVKGLKLSLEEEGFEVDAAYDGEEGLDKVRLGNYDLVILDIMLPKLDGFSVCREIRTFSNIPIIMLTA
RGDDIDKIVGIEIGADDYLAKPFNTRELTARIRALLRRATNPYTKRKDEIRRGELYINIPERAVYKRGKRIELTNKEFEI
LVLLASNPGKVYTKDKLLDLIWGFDFYGDTNTVTVHVRKLREKIEDDPANPQYIFTKWGAGYYMK

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=41.3333333333333, Blast_Score=183, Evalue=8e-48,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=36.1233480176211, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=39.2857142857143, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=39.0909090909091, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=36.3636363636364, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=35.6828193832599, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=37.4449339207048, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=37.5545851528384, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1790552, Length=203, Percent_Identity=37.9310344827586, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=32.2869955156951, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=33.0434782608696, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.5291479820628, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=31.5315315315315, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=28.0851063829787, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1788550, Length=133, Percent_Identity=30.0751879699248, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=30.8333333333333, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=113, Percent_Identity=35.3982300884956, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=142, Percent_Identity=32.3943661971831, Blast_Score=60, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=101, Percent_Identity=32.6732673267327, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26035; Mature: 26035

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLLIIDDEEMFVKGLKLSLEEEGFEVDAAYDGEEGLDKVRLGNYDLVILDIMLPKLDG
CCCEEEECCHHHHHHHHEEEECCCCEEEEECCCCCCCCCCEECCCCCEEEEEEECCCCCH
FSVCREIRTFSNIPIIMLTARGDDIDKIVGIEIGADDYLAKPFNTRELTARIRALLRRAT
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHC
NPYTKRKDEIRRGELYINIPERAVYKRGKRIELTNKEFEILVLLASNPGKVYTKDKLLDL
CCCCCCHHHHCCCEEEEECCHHHHHHCCCEEEEECCCEEEEEEEECCCCCEEEHHHHHHH
IWGFDFYGDTNTVTVHVRKLREKIEDDPANPQYIFTKWGAGYYMK
HHCCEEECCCCEEEEEHHHHHHHHHCCCCCCCEEEEECCCCEECC
>Mature Secondary Structure
MEKLLIIDDEEMFVKGLKLSLEEEGFEVDAAYDGEEGLDKVRLGNYDLVILDIMLPKLDG
CCCEEEECCHHHHHHHHEEEECCCCEEEEECCCCCCCCCCEECCCCCEEEEEEECCCCCH
FSVCREIRTFSNIPIIMLTARGDDIDKIVGIEIGADDYLAKPFNTRELTARIRALLRRAT
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHC
NPYTKRKDEIRRGELYINIPERAVYKRGKRIELTNKEFEILVLLASNPGKVYTKDKLLDL
CCCCCCHHHHCCCEEEEECCHHHHHHCCCEEEEECCCEEEEEEEECCCCCEEEHHHHHHH
IWGFDFYGDTNTVTVHVRKLREKIEDDPANPQYIFTKWGAGYYMK
HHCCEEECCCCEEEEEHHHHHHHHHCCCCCCCEEEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]