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The map label for this gene is crr [H]

Identifier: 167039074

GI number: 167039074

Start: 424781

End: 425266

Strand: Direct

Name: crr [H]

Synonym: Teth514_0413

Alternate gene names: 167039074

Gene position: 424781-425266 (Clockwise)

Preceding gene: 167039073

Following gene: 167039075

Centisome position: 17.29

GC content: 29.84

Gene sequence:

>486_bases
ATGTTTAACATATTTAAAAAGAAAAAATACGTAGATATATATTCTCCTATTAATGGTATATTATTAAAAATTGAAGATGT
GCCAGATCCTGTATTTTCTCGAAAAATGGTAGGAGATGGAGTGGCATTAGAACCCACAGAAGGTATTGTATATTCACCGG
TTAATGGAACTCTTATACAATTATTTCCTACAAAACATGCTTTGGGAATAAAAACAGAAGAAGGATTAGAAATACTAATT
CATATTGGGATGGACACAGTAGAAATGAAAGGAAATGGATTTGAAAGTTTTGTTTCAGAAGGTGAAAAAGTGAAAATAGG
AAATAAGTTGCTTAAATTTGATATGGAATTGGTTAAAAAAGAACATCCCTTGACATCTCCAATTATTATTACTAATATGG
ATATAGTGGATAAAATTGTAAAAGAATCTTATGGTGAGGAAGTAAAAGCAGGAAAGACAAAGATTATGAGAGTATACCTC
AAGTGA

Upstream 100 bases:

>100_bases
TTAGGCGGCCGTAAACTGGCCGCCATCAAAATTATTTTAAGAAGTTTGAAATATATGGGTATAATAAGATATTATTAAAA
TACAGAAAGGGATGGTATAC

Downstream 100 bases:

>100_bases
AAAGTGAGGTATTAATTATGTATCAAGTGGTAAAAGTTCTTAACAATAATGTGTGTATGGCAAAAGACGATAAAGGTATG
GAATGCATAGTCGTTGGAAA

Product: PTS system, glucose subfamily, IIA subunit

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Glc; EIII-Glc; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MFNIFKKKKYVDIYSPINGILLKIEDVPDPVFSRKMVGDGVALEPTEGIVYSPVNGTLIQLFPTKHALGIKTEEGLEILI
HIGMDTVEMKGNGFESFVSEGEKVKIGNKLLKFDMELVKKEHPLTSPIIITNMDIVDKIVKESYGEEVKAGKTKIMRVYL
K

Sequences:

>Translated_161_residues
MFNIFKKKKYVDIYSPINGILLKIEDVPDPVFSRKMVGDGVALEPTEGIVYSPVNGTLIQLFPTKHALGIKTEEGLEILI
HIGMDTVEMKGNGFESFVSEGEKVKIGNKLLKFDMELVKKEHPLTSPIIITNMDIVDKIVKESYGEEVKAGKTKIMRVYL
K
>Mature_161_residues
MFNIFKKKKYVDIYSPINGILLKIEDVPDPVFSRKMVGDGVALEPTEGIVYSPVNGTLIQLFPTKHALGIKTEEGLEILI
HIGMDTVEMKGNGFESFVSEGEKVKIGNKLLKFDMELVKKEHPLTSPIIITNMDIVDKIVKESYGEEVKAGKTKIMRVYL
K

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788757, Length=154, Percent_Identity=39.6103896103896, Blast_Score=130, Evalue=3e-32,
Organism=Escherichia coli, GI1786894, Length=148, Percent_Identity=38.5135135135135, Blast_Score=120, Evalue=4e-29,
Organism=Escherichia coli, GI1790159, Length=123, Percent_Identity=40.650406504065, Blast_Score=105, Evalue=1e-24,

Paralogues:

None

Copy number: 3540 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR001127 [H]

Pfam domain/function: PF00358 PTS_EIIA_1 [H]

EC number: 2.7.1.69

Molecular weight: Translated: 18071; Mature: 18071

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNIFKKKKYVDIYSPINGILLKIEDVPDPVFSRKMVGDGVALEPTEGIVYSPVNGTLIQ
CCCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHCCCCEEECCCCCEEEECCCCEEEE
LFPTKHALGIKTEEGLEILIHIGMDTVEMKGNGFESFVSEGEKVKIGNKLLKFDMELVKK
EECCCCCCCCCCCCCEEEEEEECCCEEEECCCCHHHHHCCCCEEECCHHHHHHHHHHHHH
EHPLTSPIIITNMDIVDKIVKESYGEEVKAGKTKIMRVYLK
CCCCCCCEEEECHHHHHHHHHHHCCCHHHCCCEEEEEEEEC
>Mature Secondary Structure
MFNIFKKKKYVDIYSPINGILLKIEDVPDPVFSRKMVGDGVALEPTEGIVYSPVNGTLIQ
CCCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHCCCCEEECCCCCEEEECCCCEEEE
LFPTKHALGIKTEEGLEILIHIGMDTVEMKGNGFESFVSEGEKVKIGNKLLKFDMELVKK
EECCCCCCCCCCCCCEEEEEEECCCEEEECCCCHHHHHCCCCEEECCHHHHHHHHHHHHH
EHPLTSPIIITNMDIVDKIVKESYGEEVKAGKTKIMRVYLK
CCCCCCCEEEECHHHHHHHHHHHCCCHHHCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]