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The map label for this gene is mcp4 [H]

Identifier: 167039071

GI number: 167039071

Start: 420101

End: 421747

Strand: Direct

Name: mcp4 [H]

Synonym: Teth514_0410

Alternate gene names: 167039071

Gene position: 420101-421747 (Clockwise)

Preceding gene: 167039070

Following gene: 167039072

Centisome position: 17.1

GC content: 31.09

Gene sequence:

>1647_bases
ATGGGAAAAACTATTCGAGCTCAGGTTGTGCGATCTTTTGTAATTATAGGCATTTTAACAGTTATACTTTCGGTGATTGT
GAATTTAGGACTTATAAATACTATTAACAACATTGAAAAATTAAGAAAATATGTGGTAAATCAAGTCATTAACGTGTCAA
ATGCCCAAGTTCAAATTGCGGTATTAAGTGGCAATATTCAACAAACTTTAAATGACTATATGAATGGCAATGCGACAAAT
TTTTCCGTTGGAGTTCCAATTAGTTCGATGGAGACCTACATTGCTAATATCCAAAATAGCTTAGATGACTATAAAAATAC
CAAGAATTACGACTCACTTAATAAAAATTTATTGCTAATTAAAGAAGGTATTCAGAACCTAAAGAAAGCAGTAAATGAAT
TACCCGAAAAGTATGACTCTGTTAATGATAGCGACAAAGTAGTAACTATTACTTATTATTTGAATCATATACAAAGTGCT
TTGAATGATTTTAGTTCTACATATTCCCAGGGCTTTTTACCCTATTTTAATCAAATGATAGAAAATAATAAAAGAAATTT
TTACATATCACTAGGAATGAGTATTGTAATACTATTGATAATTTTAATTTATGCAGCGATAATAATAAGAAAATTAAGGA
AATATGCAAAACTTATTAATTCTGAAATCATAAATGCAGAAAAGCAATCAGAAGAAGTCATGAATTACGCGGTAAACATA
AGAAACAAATCAGAAGAAAATACTATGAACATAACTTCTTCAAAACAAGGTTTAGAGGATTTAGTGAATGGGATTAACAT
AATTTCAGAAAATATAAATGAAGTTGCTGAGTCTATTACTAAAGTTTCACAGACTAATGAAAATTTGTCACAAGTCTCCG
ATAAACTTATGAGAGACATGAATGAAGCAATGATGAGAATCAAAGAAATAGAAGAAAATGCAAACAGGCAAGGAGAAGAA
GTTAAATCATTAATTGAATCTTTACAAGAAAGCTTGGAAAACTCCAAAAATACTTCAAAACAACTGAATGAACTAGAGAA
AAGAATGGGTGGTATAAAAGATATTCTTTATTCAATATCAGATATAGCGGAACAGACGAATCTTTTGGCACTTAATGCGG
CAATTGAAGCAGCAAGAGCTGGAGAAAACGGAAGAGGATTTGCAGTTGTGGCAGAAGAAATAAGGAAACTTGCAGCGCAA
TCGACAGAAAGTGTAGAAAGAATAGGAGAAATAATAGAATCTCTTACCCAATTTACAAGAAATACTGTGGATAATGTCAT
CAAAAACATTGATAATTCTACAAAAGCATCTCAGGAGGTAAATAAAGTATTAGATATATTTGAACAGACAAAAGAAGGGT
TTGACAAAGTCGCTGATATTATTAGTGAAATTTCTGTTGCGGCAGAAGAGACGGCTGTAAGTTCTAGTCAAACGCTGCAG
GCCATGAAAAACGTAATGGCAGCATCACAAAATATATCTGCACAAGTAGAAGAATTACTTGCCTCATCTGAGCAGCTTCT
TGCAGAGATAAATGTAGTAGATGAAAATAATTTAAAAAATCTTGAACACATAAAAGAACAAGTTGAATATGCAGAAAATC
AAAAAGCTAATATGCAGAAAATTACAAGTATAGTGATGCAGTTGTAA

Upstream 100 bases:

>100_bases
GTTTTGTAAGAAGAACCGCTTATTTCTATTAAATTTTTGCCGATTTAAACCGATAAATAAATACGGAATTTTTATTTTTA
GTTAGAGGGGAGAAGTGTAA

Downstream 100 bases:

>100_bases
TAATTGACATACACTACTTTATGGTATATAATTTAGTTAAACAGCGTGCGACGGGTTACGGCATGAGCTGGGAAGGTAGC
TATTACCTTGCCAGCTTTTA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MGKTIRAQVVRSFVIIGILTVILSVIVNLGLINTINNIEKLRKYVVNQVINVSNAQVQIAVLSGNIQQTLNDYMNGNATN
FSVGVPISSMETYIANIQNSLDDYKNTKNYDSLNKNLLLIKEGIQNLKKAVNELPEKYDSVNDSDKVVTITYYLNHIQSA
LNDFSSTYSQGFLPYFNQMIENNKRNFYISLGMSIVILLIILIYAAIIIRKLRKYAKLINSEIINAEKQSEEVMNYAVNI
RNKSEENTMNITSSKQGLEDLVNGINIISENINEVAESITKVSQTNENLSQVSDKLMRDMNEAMMRIKEIEENANRQGEE
VKSLIESLQESLENSKNTSKQLNELEKRMGGIKDILYSISDIAEQTNLLALNAAIEAARAGENGRGFAVVAEEIRKLAAQ
STESVERIGEIIESLTQFTRNTVDNVIKNIDNSTKASQEVNKVLDIFEQTKEGFDKVADIISEISVAAEETAVSSSQTLQ
AMKNVMAASQNISAQVEELLASSEQLLAEINVVDENNLKNLEHIKEQVEYAENQKANMQKITSIVMQL

Sequences:

>Translated_548_residues
MGKTIRAQVVRSFVIIGILTVILSVIVNLGLINTINNIEKLRKYVVNQVINVSNAQVQIAVLSGNIQQTLNDYMNGNATN
FSVGVPISSMETYIANIQNSLDDYKNTKNYDSLNKNLLLIKEGIQNLKKAVNELPEKYDSVNDSDKVVTITYYLNHIQSA
LNDFSSTYSQGFLPYFNQMIENNKRNFYISLGMSIVILLIILIYAAIIIRKLRKYAKLINSEIINAEKQSEEVMNYAVNI
RNKSEENTMNITSSKQGLEDLVNGINIISENINEVAESITKVSQTNENLSQVSDKLMRDMNEAMMRIKEIEENANRQGEE
VKSLIESLQESLENSKNTSKQLNELEKRMGGIKDILYSISDIAEQTNLLALNAAIEAARAGENGRGFAVVAEEIRKLAAQ
STESVERIGEIIESLTQFTRNTVDNVIKNIDNSTKASQEVNKVLDIFEQTKEGFDKVADIISEISVAAEETAVSSSQTLQ
AMKNVMAASQNISAQVEELLASSEQLLAEINVVDENNLKNLEHIKEQVEYAENQKANMQKITSIVMQL
>Mature_547_residues
GKTIRAQVVRSFVIIGILTVILSVIVNLGLINTINNIEKLRKYVVNQVINVSNAQVQIAVLSGNIQQTLNDYMNGNATNF
SVGVPISSMETYIANIQNSLDDYKNTKNYDSLNKNLLLIKEGIQNLKKAVNELPEKYDSVNDSDKVVTITYYLNHIQSAL
NDFSSTYSQGFLPYFNQMIENNKRNFYISLGMSIVILLIILIYAAIIIRKLRKYAKLINSEIINAEKQSEEVMNYAVNIR
NKSEENTMNITSSKQGLEDLVNGINIISENINEVAESITKVSQTNENLSQVSDKLMRDMNEAMMRIKEIEENANRQGEEV
KSLIESLQESLENSKNTSKQLNELEKRMGGIKDILYSISDIAEQTNLLALNAAIEAARAGENGRGFAVVAEEIRKLAAQS
TESVERIGEIIESLTQFTRNTVDNVIKNIDNSTKASQEVNKVLDIFEQTKEGFDKVADIISEISVAAEETAVSSSQTLQA
MKNVMAASQNISAQVEELLASSEQLLAEINVVDENNLKNLEHIKEQVEYAENQKANMQKITSIVMQL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=268, Percent_Identity=31.3432835820896, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788195, Length=243, Percent_Identity=30.0411522633745, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI2367378, Length=395, Percent_Identity=24.8101265822785, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787690, Length=301, Percent_Identity=27.2425249169435, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789453, Length=166, Percent_Identity=32.5301204819277, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 61231; Mature: 61100

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTIRAQVVRSFVIIGILTVILSVIVNLGLINTINNIEKLRKYVVNQVINVSNAQVQIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VLSGNIQQTLNDYMNGNATNFSVGVPISSMETYIANIQNSLDDYKNTKNYDSLNKNLLLI
EECCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHH
KEGIQNLKKAVNELPEKYDSVNDSDKVVTITYYLNHIQSALNDFSSTYSQGFLPYFNQMI
HHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ENNKRNFYISLGMSIVILLIILIYAAIIIRKLRKYAKLINSEIINAEKQSEEVMNYAVNI
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHC
RNKSEENTMNITSSKQGLEDLVNGINIISENINEVAESITKVSQTNENLSQVSDKLMRDM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NEAMMRIKEIEENANRQGEEVKSLIESLQESLENSKNTSKQLNELEKRMGGIKDILYSIS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHH
DIAEQTNLLALNAAIEAARAGENGRGFAVVAEEIRKLAAQSTESVERIGEIIESLTQFTR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
NTVDNVIKNIDNSTKASQEVNKVLDIFEQTKEGFDKVADIISEISVAAEETAVSSSQTLQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMKNVMAASQNISAQVEELLASSEQLLAEINVVDENNLKNLEHIKEQVEYAENQKANMQK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
ITSIVMQL
HHHHHHCC
>Mature Secondary Structure 
GKTIRAQVVRSFVIIGILTVILSVIVNLGLINTINNIEKLRKYVVNQVINVSNAQVQIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VLSGNIQQTLNDYMNGNATNFSVGVPISSMETYIANIQNSLDDYKNTKNYDSLNKNLLLI
EECCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHH
KEGIQNLKKAVNELPEKYDSVNDSDKVVTITYYLNHIQSALNDFSSTYSQGFLPYFNQMI
HHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ENNKRNFYISLGMSIVILLIILIYAAIIIRKLRKYAKLINSEIINAEKQSEEVMNYAVNI
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHC
RNKSEENTMNITSSKQGLEDLVNGINIISENINEVAESITKVSQTNENLSQVSDKLMRDM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
NEAMMRIKEIEENANRQGEEVKSLIESLQESLENSKNTSKQLNELEKRMGGIKDILYSIS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHH
DIAEQTNLLALNAAIEAARAGENGRGFAVVAEEIRKLAAQSTESVERIGEIIESLTQFTR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
NTVDNVIKNIDNSTKASQEVNKVLDIFEQTKEGFDKVADIISEISVAAEETAVSSSQTLQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMKNVMAASQNISAQVEELLASSEQLLAEINVVDENNLKNLEHIKEQVEYAENQKANMQK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
ITSIVMQL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]