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The map label for this gene is cdd [H]

Identifier: 167039068

GI number: 167039068

Start: 417059

End: 417466

Strand: Direct

Name: cdd [H]

Synonym: Teth514_0407

Alternate gene names: 167039068

Gene position: 417059-417466 (Clockwise)

Preceding gene: 167039067

Following gene: 167039069

Centisome position: 16.97

GC content: 38.97

Gene sequence:

>408_bases
GTGGAATATAAAGATTATGAGAAGCTTGTGGAATTAGCGAAAGATGCAAGGGAGAAGGCCTATGTGCCTTACTCCCACTT
TAAAGTAGGTGCATGTGTTCTTACTGAAGATGGAAAAGCTTACCAAGGATGCAATATTGAGAATGCTTCTTATGGTCTTA
CCAATTGTGCAGAAAGGACAGCACTTTTTAGCGCTTATGCAAATGGAGATAGAAAATTAAAAGCAATTGCTGTAGTTGCA
GATACTGAAGGTCCTGTTTCTCCTTGTGGTGCATGTAGACAGGTAATGATGGAATTGGGTGGAGAAGACATGGTTGTTAT
ATTGAGCAACATGAAAGGCGATTATGCTGTTGTCACTGTTAAAGATTTGTTGCCAGGTGCTTTTACCTCAAAAGATTTAG
AGAAATAA

Upstream 100 bases:

>100_bases
AAACAATACGCCAATCCTTTATTCTTCTAACTATTTTAATGCTTCTAAATTCGACTTCTATATTATACGCAAAAGAATAT
TATGAAAGTAGGTGTATAAA

Downstream 100 bases:

>100_bases
TACGGACATAAGTTCATAGAAGAGGTGGTAAAATGTTCAAAAGAGTCATACTAATAGTTTTGGATAGCGTAGGAGTAGGA
GAATTGCCAGACGCTTATAA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MEYKDYEKLVELAKDAREKAYVPYSHFKVGACVLTEDGKAYQGCNIENASYGLTNCAERTALFSAYANGDRKLKAIAVVA
DTEGPVSPCGACRQVMMELGGEDMVVILSNMKGDYAVVTVKDLLPGAFTSKDLEK

Sequences:

>Translated_135_residues
MEYKDYEKLVELAKDAREKAYVPYSHFKVGACVLTEDGKAYQGCNIENASYGLTNCAERTALFSAYANGDRKLKAIAVVA
DTEGPVSPCGACRQVMMELGGEDMVVILSNMKGDYAVVTVKDLLPGAFTSKDLEK
>Mature_135_residues
MEYKDYEKLVELAKDAREKAYVPYSHFKVGACVLTEDGKAYQGCNIENASYGLTNCAERTALFSAYANGDRKLKAIAVVA
DTEGPVSPCGACRQVMMELGGEDMVVILSNMKGDYAVVTVKDLLPGAFTSKDLEK

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=130, Percent_Identity=46.9230769230769, Blast_Score=128, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17540514, Length=128, Percent_Identity=50, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17551074, Length=129, Percent_Identity=48.8372093023256, Blast_Score=115, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6323274, Length=137, Percent_Identity=38.6861313868613, Blast_Score=94, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24582741, Length=128, Percent_Identity=41.40625, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24582744, Length=142, Percent_Identity=37.3239436619718, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920920, Length=138, Percent_Identity=35.5072463768116, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14675; Mature: 14675

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYKDYEKLVELAKDAREKAYVPYSHFKVGACVLTEDGKAYQGCNIENASYGLTNCAERT
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCCCHHHHHHH
ALFSAYANGDRKLKAIAVVADTEGPVSPCGACRQVMMELGGEDMVVILSNMKGDYAVVTV
HHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEH
KDLLPGAFTSKDLEK
HHHCCCCCCCCCCCC
>Mature Secondary Structure
MEYKDYEKLVELAKDAREKAYVPYSHFKVGACVLTEDGKAYQGCNIENASYGLTNCAERT
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCCCHHHHHHH
ALFSAYANGDRKLKAIAVVADTEGPVSPCGACRQVMMELGGEDMVVILSNMKGDYAVVTV
HHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEH
KDLLPGAFTSKDLEK
HHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]