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The map label for this gene is fchA [H]

Identifier: 167039063

GI number: 167039063

Start: 410756

End: 411394

Strand: Direct

Name: fchA [H]

Synonym: Teth514_0400

Alternate gene names: 167039063

Gene position: 410756-411394 (Clockwise)

Preceding gene: 167039062

Following gene: 167039064

Centisome position: 16.72

GC content: 35.99

Gene sequence:

>639_bases
ATGCTGATTGATGATTCATTAAAGGAGTATATTGAAAAAGTGGCCTCAAAATCACCAACGCCGGGAGGGGGAAGTGTATC
GGCGGCAGCGGCAAGCCTTGGGATTGCCCTTTCTTCTATGGTTTACAATCTTACAATAGGGCGAAAATTTTATGAGGAAT
ATACTGATGATATTAAAGAAGAGATTCAACAAGGGCTTAGTATATGTAATCGACTTCTTGCAGAATATGTAAAGCTTGTT
GATGAAGACACTGTAGCTTATGACGAAGTGATGAAAGCCCTTAAAATGCCAAAAGATACTGAAGAAAATAAAAAAATAAG
AAACGAAGCACTTCAAAAAGCTTATATTAACGCTATGAATGTTCCTCTAAAACTTGCGAGGTTGTGTGGAGAGGCTTTTA
CTCCTACGATGTTGATTGCGGAATACGGGAATCCTAATGCCATATCTGATGCGGCAGTTGGAGCGATTCTACTATATGCA
GCAATAGAGGGAGCTGTTTTGAATGTTAAAGTGAATATTCCTTATATTAAAGATAGAGAAATTGCCGAAAAGGCAAACAA
AGAATGTGATGAAATTTTGGCAAAATACAAAAATATAAGGGATGAAATTGTAAATAAAGTTTTAAATAAAATTTCTTGA

Upstream 100 bases:

>100_bases
TATTGTAACAATTTTTTTGGCAGTTGTATTACGAAAATTATATATCATTGGTATAATAGGTAGTGGGGGAAAATATATAC
ACAGAGAAGGAGATGGTTTT

Downstream 100 bases:

>100_bases
TAGAGTGCGATGAGCACTCTTTATTTTGCGCTACCTTTAAGCTAATAGTGCCGAAAGTTCTTAAAATAAGCTTTAAATTT
TGCATAAAAAAATAGTTATT

Product: formiminotransferase-cyclodeaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MLIDDSLKEYIEKVASKSPTPGGGSVSAAAASLGIALSSMVYNLTIGRKFYEEYTDDIKEEIQQGLSICNRLLAEYVKLV
DEDTVAYDEVMKALKMPKDTEENKKIRNEALQKAYINAMNVPLKLARLCGEAFTPTMLIAEYGNPNAISDAAVGAILLYA
AIEGAVLNVKVNIPYIKDREIAEKANKECDEILAKYKNIRDEIVNKVLNKIS

Sequences:

>Translated_212_residues
MLIDDSLKEYIEKVASKSPTPGGGSVSAAAASLGIALSSMVYNLTIGRKFYEEYTDDIKEEIQQGLSICNRLLAEYVKLV
DEDTVAYDEVMKALKMPKDTEENKKIRNEALQKAYINAMNVPLKLARLCGEAFTPTMLIAEYGNPNAISDAAVGAILLYA
AIEGAVLNVKVNIPYIKDREIAEKANKECDEILAKYKNIRDEIVNKVLNKIS
>Mature_212_residues
MLIDDSLKEYIEKVASKSPTPGGGSVSAAAASLGIALSSMVYNLTIGRKFYEEYTDDIKEEIQQGLSICNRLLAEYVKLV
DEDTVAYDEVMKALKMPKDTEENKKIRNEALQKAYINAMNVPLKLARLCGEAFTPTMLIAEYGNPNAISDAAVGAILLYA
AIEGAVLNVKVNIPYIKDREIAEKANKECDEILAKYKNIRDEIVNKVLNKIS

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=193, Percent_Identity=32.6424870466321, Blast_Score=67, Evalue=8e-12,
Organism=Homo sapiens, GI11140815, Length=193, Percent_Identity=32.6424870466321, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 23385; Mature: 23385

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDDSLKEYIEKVASKSPTPGGGSVSAAAASLGIALSSMVYNLTIGRKFYEEYTDDIKE
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIQQGLSICNRLLAEYVKLVDEDTVAYDEVMKALKMPKDTEENKKIRNEALQKAYINAMN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
VPLKLARLCGEAFTPTMLIAEYGNPNAISDAAVGAILLYAAIEGAVLNVKVNIPYIKDRE
CHHHHHHHHHHHCCCHHHEEECCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHH
IAEKANKECDEILAKYKNIRDEIVNKVLNKIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLIDDSLKEYIEKVASKSPTPGGGSVSAAAASLGIALSSMVYNLTIGRKFYEEYTDDIKE
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIQQGLSICNRLLAEYVKLVDEDTVAYDEVMKALKMPKDTEENKKIRNEALQKAYINAMN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
VPLKLARLCGEAFTPTMLIAEYGNPNAISDAAVGAILLYAAIEGAVLNVKVNIPYIKDRE
CHHHHHHHHHHHCCCHHHEEECCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHH
IAEKANKECDEILAKYKNIRDEIVNKVLNKIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]