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The map label for this gene is adcA [H]

Identifier: 167038946

GI number: 167038946

Start: 297950

End: 298831

Strand: Reverse

Name: adcA [H]

Synonym: Teth514_0278

Alternate gene names: 167038946

Gene position: 298831-297950 (Counterclockwise)

Preceding gene: 167038947

Following gene: 167038945

Centisome position: 12.16

GC content: 33.9

Gene sequence:

>882_bases
ATGAAAAAAACTTTAATCGCTATACTGCTTATCATGGCTTTAATTTTAGGTATAACCTCTTGTGGCACAAAAACAGTAGA
ATCTTCAAAACCAGTAGTGTACGCATCTTTTTATCCAATTTATGACCTTGCATCAAAAATTGGTGGTGACAAAATAACAG
TAAGAACTATAATACCGCCAGGAGTCGAACCCCACGATTGGGAACCTACCACAAAAGACGTGGCTGAAATGACAAAGGCA
AAAACTATCCTTTACTTAGGTTTGGGAATGGACTCTTGGATTGACAAAATAAAAACCAATGCTCCAAATGTAACATTTTA
TGAAGTATCAAAAGGCATAACTCCAATTGTTGAAGGCAATCAAACAAATCCTCACATATGGCTTTCTCCTAAAGAGACCT
TGATAATGGCTAAAAACATAAATGAAGCCTTGCAAAAGACCTTTCCGAATGATAAAGATTATTTTGAAAAAAACTATCAA
AATTTAAAAACTACATTAGAAACTCTTGATAAAGAGTACACTGAGACTCTTTCACAGACAAAGCACAAAACCTTTATTGT
ATACCACCGCGCTTTTGATTATTTAGCAAGAGACTATGGCTTAAAGCAAGAAGCATTAGTAGGTTCAGATGAAGAAGCAG
AGGTAAGCCCTGCTAGAATGACAGAAATTATAAATCTTATAAAAAGTAAAAATATAAAATACATTTTCACAGAACCCTTG
ACTTCTCCAAAGCCTATACAGACTATAGCAAAAGAAACAGGAGTACAAGTTTTGCCTCTTAGCACAATCGAAGGGCTTAC
TAAAGAAGATATAAAGAAAAAAGGAGATTACATCTCTTTAATGAAACAAAACCTTGAAAACTTAAAAAAAGGATTGGAGT
AG

Upstream 100 bases:

>100_bases
CCAAATAAAAGACTTTGAAATTGTAGACCACAAAATAGAAATCGTTGGTTATTGCAAAGATTGCAGGAGCAATAAAAACT
AACTATAGGAGGTAATATTT

Downstream 100 bases:

>100_bases
GTGAAAATGAACTTGGTTGAACTTAAGAATGTCAGCTTTGCTTATGACACTAAAAAAATATTAAATAATATCTCTTTAAA
AATAAATAAAGGAGAATTTG

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKKTLIAILLIMALILGITSCGTKTVESSKPVVYASFYPIYDLASKIGGDKITVRTIIPPGVEPHDWEPTTKDVAEMTKA
KTILYLGLGMDSWIDKIKTNAPNVTFYEVSKGITPIVEGNQTNPHIWLSPKETLIMAKNINEALQKTFPNDKDYFEKNYQ
NLKTTLETLDKEYTETLSQTKHKTFIVYHRAFDYLARDYGLKQEALVGSDEEAEVSPARMTEIINLIKSKNIKYIFTEPL
TSPKPIQTIAKETGVQVLPLSTIEGLTKEDIKKKGDYISLMKQNLENLKKGLE

Sequences:

>Translated_293_residues
MKKTLIAILLIMALILGITSCGTKTVESSKPVVYASFYPIYDLASKIGGDKITVRTIIPPGVEPHDWEPTTKDVAEMTKA
KTILYLGLGMDSWIDKIKTNAPNVTFYEVSKGITPIVEGNQTNPHIWLSPKETLIMAKNINEALQKTFPNDKDYFEKNYQ
NLKTTLETLDKEYTETLSQTKHKTFIVYHRAFDYLARDYGLKQEALVGSDEEAEVSPARMTEIINLIKSKNIKYIFTEPL
TSPKPIQTIAKETGVQVLPLSTIEGLTKEDIKKKGDYISLMKQNLENLKKGLE
>Mature_293_residues
MKKTLIAILLIMALILGITSCGTKTVESSKPVVYASFYPIYDLASKIGGDKITVRTIIPPGVEPHDWEPTTKDVAEMTKA
KTILYLGLGMDSWIDKIKTNAPNVTFYEVSKGITPIVEGNQTNPHIWLSPKETLIMAKNINEALQKTFPNDKDYFEKNYQ
NLKTTLETLDKEYTETLSQTKHKTFIVYHRAFDYLARDYGLKQEALVGSDEEAEVSPARMTEIINLIKSKNIKYIFTEPL
TSPKPIQTIAKETGVQVLPLSTIEGLTKEDIKKKGDYISLMKQNLENLKKGLE

Specific function: Part of the ATP-driven transport system AdcABC for zinc. Required for transformability [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=254, Percent_Identity=20.0787401574803, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 33024; Mature: 33024

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLIAILLIMALILGITSCGTKTVESSKPVVYASFYPIYDLASKIGGDKITVRTIIPP
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCEEEEEEECCC
GVEPHDWEPTTKDVAEMTKAKTILYLGLGMDSWIDKIKTNAPNVTFYEVSKGITPIVEGN
CCCCCCCCCCHHHHHHHHHHHEEEEEECCHHHHHHHHHCCCCCEEEEECCCCCCCEECCC
QTNPHIWLSPKETLIMAKNINEALQKTFPNDKDYFEKNYQNLKTTLETLDKEYTETLSQT
CCCCEEEECCHHHEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KHKTFIVYHRAFDYLARDYGLKQEALVGSDEEAEVSPARMTEIINLIKSKNIKYIFTEPL
CCCEEEEEHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
TSPKPIQTIAKETGVQVLPLSTIEGLTKEDIKKKGDYISLMKQNLENLKKGLE
CCCHHHHHHHHHCCCEEEEHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKTLIAILLIMALILGITSCGTKTVESSKPVVYASFYPIYDLASKIGGDKITVRTIIPP
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCEEEEEEECCC
GVEPHDWEPTTKDVAEMTKAKTILYLGLGMDSWIDKIKTNAPNVTFYEVSKGITPIVEGN
CCCCCCCCCCHHHHHHHHHHHEEEEEECCHHHHHHHHHCCCCCEEEEECCCCCCCEECCC
QTNPHIWLSPKETLIMAKNINEALQKTFPNDKDYFEKNYQNLKTTLETLDKEYTETLSQT
CCCCEEEECCHHHEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KHKTFIVYHRAFDYLARDYGLKQEALVGSDEEAEVSPARMTEIINLIKSKNIKYIFTEPL
CCCEEEEEHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
TSPKPIQTIAKETGVQVLPLSTIEGLTKEDIKKKGDYISLMKQNLENLKKGLE
CCCHHHHHHHHHCCCEEEEHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]