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The map label for this gene is rbsK [H]

Identifier: 167038832

GI number: 167038832

Start: 162683

End: 163612

Strand: Direct

Name: rbsK [H]

Synonym: Teth514_0162

Alternate gene names: 167038832

Gene position: 162683-163612 (Clockwise)

Preceding gene: 167038831

Following gene: 167038833

Centisome position: 6.62

GC content: 34.52

Gene sequence:

>930_bases
ATGGAGAAGATAGTTGTTGTTGGAAGTATTAATATGGACGTTGTGATACGAGTTCCGCATATTCCTGTAGTTGGTGAGAC
AGTTATTGCTTATGATTTAAAAAATTACGGCGGTGGTAAAGGCGCAAATCAAGCGGTATCAATTGCAAGGTTGGGTGGAA
CGGTCTTTATGATCGGCAGAGTGGGAAATGATGAATATGGTAAGAAATTATATGAGGATTTAAAAAATGATAGCGTTGAC
ATTAAAGGAATAGAATTTGATTACGAAATACCGACGGGTACAGCTTATATTAATGTGAGTGAAAGAGGAGAAAATAACAT
AGTTGTTTATCAGGGAGCAAATAAAAGGCTTAATATAGAGCAAATAGAAAAACACGAAGATATTTTTGATGAAGCAAAAA
TGTGTGTAATTCAGTTAGAAATACCAGTTGAGACAGTAGAATTTGTAGTGGATTTATGTTACCGAAAGGGTATAAAAGTC
ATATTAAATCCTGCACCAGCATGTGAATTGCCTGATACGCTCTTAGAAAAGGTTTATATTTTAACTCCAAATGAAACAGA
ATTAGCTCTTTTATCTAGAAGTAAAACAGAAACAATTGCAGATATAAAAAAGGCCTCAAAATATTTGCTGGACAAAGGAG
TTCAAAACGTTATAACAACTATTGGAGAAAAAGGAAGCTTTTTTATCAATAAGGATACAGAAAAACTATTTGATGCGATC
AAAGTTACTGCTGTTGATACAACAGCAGCAGGTGATTCATTTACAGGAGCATTAGCAGTGGCATTAAGTGAAGGGAAGAA
CATTGAAAGTGCAATAGAATTTGCTACATACGTAGCAGCATTAACGGTTACTAAAGAAGGCGCTCAGTCATCCTTGCCTT
ATAGAGATGAGGTAGAAAAATTTATTAAAGAAAGGGGTTATAACAAATGA

Upstream 100 bases:

>100_bases
TGTAGAAGGGAAAAAGTTAAAGAAAAAAATTATTAATTTTAGACCACAGTTGATAATACGCCAAAGCACAAAAAATATTG
GCTAAAGGTGGTAAAAAAAG

Downstream 100 bases:

>100_bases
AAAAGACATATTTGCTGAATAGTGAAATTTCAGAAGTTGTTGCAAGATTAGGGCATACAGATTTGTTGGTGATTGCTGAT
AGTGGATTACCTATACCAGA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MEKIVVVGSINMDVVIRVPHIPVVGETVIAYDLKNYGGGKGANQAVSIARLGGTVFMIGRVGNDEYGKKLYEDLKNDSVD
IKGIEFDYEIPTGTAYINVSERGENNIVVYQGANKRLNIEQIEKHEDIFDEAKMCVIQLEIPVETVEFVVDLCYRKGIKV
ILNPAPACELPDTLLEKVYILTPNETELALLSRSKTETIADIKKASKYLLDKGVQNVITTIGEKGSFFINKDTEKLFDAI
KVTAVDTTAAGDSFTGALAVALSEGKNIESAIEFATYVAALTVTKEGAQSSLPYRDEVEKFIKERGYNK

Sequences:

>Translated_309_residues
MEKIVVVGSINMDVVIRVPHIPVVGETVIAYDLKNYGGGKGANQAVSIARLGGTVFMIGRVGNDEYGKKLYEDLKNDSVD
IKGIEFDYEIPTGTAYINVSERGENNIVVYQGANKRLNIEQIEKHEDIFDEAKMCVIQLEIPVETVEFVVDLCYRKGIKV
ILNPAPACELPDTLLEKVYILTPNETELALLSRSKTETIADIKKASKYLLDKGVQNVITTIGEKGSFFINKDTEKLFDAI
KVTAVDTTAAGDSFTGALAVALSEGKNIESAIEFATYVAALTVTKEGAQSSLPYRDEVEKFIKERGYNK
>Mature_309_residues
MEKIVVVGSINMDVVIRVPHIPVVGETVIAYDLKNYGGGKGANQAVSIARLGGTVFMIGRVGNDEYGKKLYEDLKNDSVD
IKGIEFDYEIPTGTAYINVSERGENNIVVYQGANKRLNIEQIEKHEDIFDEAKMCVIQLEIPVETVEFVVDLCYRKGIKV
ILNPAPACELPDTLLEKVYILTPNETELALLSRSKTETIADIKKASKYLLDKGVQNVITTIGEKGSFFINKDTEKLFDAI
KVTAVDTTAAGDSFTGALAVALSEGKNIESAIEFATYVAALTVTKEGAQSSLPYRDEVEKFIKERGYNK

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=300, Percent_Identity=37, Blast_Score=166, Evalue=3e-41,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=39.1447368421053, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87082343, Length=308, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081971, Length=325, Percent_Identity=29.2307692307692, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788484, Length=290, Percent_Identity=25.5172413793103, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788491, Length=290, Percent_Identity=22.4137931034483, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788017, Length=275, Percent_Identity=23.6363636363636, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789432, Length=285, Percent_Identity=25.2631578947368, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17532905, Length=302, Percent_Identity=39.0728476821192, Blast_Score=177, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6319884, Length=332, Percent_Identity=31.9277108433735, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI20128807, Length=304, Percent_Identity=34.2105263157895, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24583886, Length=303, Percent_Identity=28.3828382838284, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33944; Mature: 33944

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIVVVGSINMDVVIRVPHIPVVGETVIAYDLKNYGGGKGANQAVSIARLGGTVFMIGR
CCEEEEEEECCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHEEHEEECCEEEEEEE
VGNDEYGKKLYEDLKNDSVDIKGIEFDYEIPTGTAYINVSERGENNIVVYQGANKRLNIE
CCCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEEEEEECCCCCCEEEECCCCCCCCHH
QIEKHEDIFDEAKMCVIQLEIPVETVEFVVDLCYRKGIKVILNPAPACELPDTLLEKVYI
HHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCEEEE
LTPNETELALLSRSKTETIADIKKASKYLLDKGVQNVITTIGEKGSFFINKDTEKLFDAI
ECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHH
KVTAVDTTAAGDSFTGALAVALSEGKNIESAIEFATYVAALTVTKEGAQSSLPYRDEVEK
EEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHH
FIKERGYNK
HHHHCCCCC
>Mature Secondary Structure
MEKIVVVGSINMDVVIRVPHIPVVGETVIAYDLKNYGGGKGANQAVSIARLGGTVFMIGR
CCEEEEEEECCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHEEHEEECCEEEEEEE
VGNDEYGKKLYEDLKNDSVDIKGIEFDYEIPTGTAYINVSERGENNIVVYQGANKRLNIE
CCCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEEEEEECCCCCCEEEECCCCCCCCHH
QIEKHEDIFDEAKMCVIQLEIPVETVEFVVDLCYRKGIKVILNPAPACELPDTLLEKVYI
HHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCEEEE
LTPNETELALLSRSKTETIADIKKASKYLLDKGVQNVITTIGEKGSFFINKDTEKLFDAI
ECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHH
KVTAVDTTAAGDSFTGALAVALSEGKNIESAIEFATYVAALTVTKEGAQSSLPYRDEVEK
EEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHH
FIKERGYNK
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]