Click here to switch to the map view.

The map label for this gene is ywlC [H]

Identifier: 167038769

GI number: 167038769

Start: 94460

End: 95524

Strand: Direct

Name: ywlC [H]

Synonym: Teth514_0096

Alternate gene names: 167038769

Gene position: 94460-95524 (Clockwise)

Preceding gene: 167038768

Following gene: 167038770

Centisome position: 3.84

GC content: 35.77

Gene sequence:

>1065_bases
ATGACAAAAATAGTACGTGTTAATAAAAATAATCCAGAAATTGAGCTTATTGATTTTGCAGCAAAAGTGATAAAAGAAGG
AGGACTTGTGGCTTTTCCTACAGAGACAGTTTATGGAATTGGAGCCAATTCTTTCAATGAAGAAGCTATAAAAAAGATAT
TTATAGCAAAGGGAAGGCCTCAAGATAACCCTCTTATTGTTCATATTGCAGAATTAGAGCAGATTTATGACCTTGTGAAA
GAAGTACCTCAAAAAGCTAAAACTCTTATGAAGAAATTTTGGCCAGGCCCTTTAACACTTATTTTTAAAAAATCACAAAA
AGTGCCTTATGTTAATACGGCTGGCATGGATACTGTAGCTATAAGGATGCCTTCAAACACAATTGCTCATCTTTTAATCA
AAAGGGCAGAAGTCCCTATATCTGCTCCCAGCGCTAATGTTTCAGGTAAGCCTAGTCCTACTGATGCTTCTCACGTTATT
GAAGATTTGTATGGAAAAGTAGATGTAATAATAGATGGAGGAAAATGTGATGTTGGCGTAGAATCTACTGTTTTGGATTT
GACAGAAAAGGTGCCGGTCATTTTAAGACCGGGAGCAGTTACTTTGGAAATGCTTAAAGAAGTGATAGGAAATGTTGAAG
TGGATCCTTCACTTTTAAAAAAGCCAAAGGAAGATTTAAAGCCTAAGTCCCCTGGCATGAAGTACAAGCATTATTCTCCT
AACGCGGAGGTCTATATAGTGACAGGAGACCTTGAGAAAGTTGTAAAAAAAATTCAAGAATTGACAGAAGAACAATTGAA
ATATGGTAAAAAAGTTGGTATAATGGCAACGGTACAAACTTCGACACAATATGAAAAAGGAGAAATTATTGTCGTAGGGG
ATAGAAATAGACCAGAGACGATAGCGAAGAATCTTTTTGCAGTTTTACGACAATTTGACAAAAAGGGAGTAGATGTCATT
TTTGCTGAAAGTTTTGGATATGACAACATTGGACTTGCTATTATGAATAGATTAGAAAAAGCTGCCGGTTATAAAGAAAT
AAGTGCTGAAGGAGAATTGCCATGA

Upstream 100 bases:

>100_bases
CAAAGGGAAAATTTCTATTTTGGGGATGATATTAGGTTTTATTGGTGGTATAATAATAACAAAGTATTTGTAAGTTTTGT
TTATGCAGGGAGTGCCTTAA

Downstream 100 bases:

>100_bases
AAGTATTATTTGTGTGCACTGGGAATACCTGTAGAAGCCCTATGGCAGAGGGACTTTTTAATGACAAAGCGAAAGCTTTC
GGTAAGGACTTTGAAGCAAA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTKIVRVNKNNPEIELIDFAAKVIKEGGLVAFPTETVYGIGANSFNEEAIKKIFIAKGRPQDNPLIVHIAELEQIYDLVK
EVPQKAKTLMKKFWPGPLTLIFKKSQKVPYVNTAGMDTVAIRMPSNTIAHLLIKRAEVPISAPSANVSGKPSPTDASHVI
EDLYGKVDVIIDGGKCDVGVESTVLDLTEKVPVILRPGAVTLEMLKEVIGNVEVDPSLLKKPKEDLKPKSPGMKYKHYSP
NAEVYIVTGDLEKVVKKIQELTEEQLKYGKKVGIMATVQTSTQYEKGEIIVVGDRNRPETIAKNLFAVLRQFDKKGVDVI
FAESFGYDNIGLAIMNRLEKAAGYKEISAEGELP

Sequences:

>Translated_354_residues
MTKIVRVNKNNPEIELIDFAAKVIKEGGLVAFPTETVYGIGANSFNEEAIKKIFIAKGRPQDNPLIVHIAELEQIYDLVK
EVPQKAKTLMKKFWPGPLTLIFKKSQKVPYVNTAGMDTVAIRMPSNTIAHLLIKRAEVPISAPSANVSGKPSPTDASHVI
EDLYGKVDVIIDGGKCDVGVESTVLDLTEKVPVILRPGAVTLEMLKEVIGNVEVDPSLLKKPKEDLKPKSPGMKYKHYSP
NAEVYIVTGDLEKVVKKIQELTEEQLKYGKKVGIMATVQTSTQYEKGEIIVVGDRNRPETIAKNLFAVLRQFDKKGVDVI
FAESFGYDNIGLAIMNRLEKAAGYKEISAEGELP
>Mature_353_residues
TKIVRVNKNNPEIELIDFAAKVIKEGGLVAFPTETVYGIGANSFNEEAIKKIFIAKGRPQDNPLIVHIAELEQIYDLVKE
VPQKAKTLMKKFWPGPLTLIFKKSQKVPYVNTAGMDTVAIRMPSNTIAHLLIKRAEVPISAPSANVSGKPSPTDASHVIE
DLYGKVDVIIDGGKCDVGVESTVLDLTEKVPVILRPGAVTLEMLKEVIGNVEVDPSLLKKPKEDLKPKSPGMKYKHYSPN
AEVYIVTGDLEKVVKKIQELTEEQLKYGKKVGIMATVQTSTQYEKGEIIVVGDRNRPETIAKNLFAVLRQFDKKGVDVIF
AESFGYDNIGLAIMNRLEKAAGYKEISAEGELP

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=210, Percent_Identity=29.5238095238095, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI87081864, Length=203, Percent_Identity=29.064039408867, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI2367210, Length=146, Percent_Identity=30.1369863013699, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17537239, Length=209, Percent_Identity=32.0574162679426, Blast_Score=88, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321269, Length=384, Percent_Identity=36.1979166666667, Blast_Score=221, Evalue=2e-58,
Organism=Drosophila melanogaster, GI78707274, Length=202, Percent_Identity=26.7326732673267, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 38998; Mature: 38867

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIVRVNKNNPEIELIDFAAKVIKEGGLVAFPTETVYGIGANSFNEEAIKKIFIAKGRP
CCEEEEECCCCCCEEEHHHHHHHHHCCCEEEECCCCEEECCCCCCCHHHHHHHHHCCCCC
QDNPLIVHIAELEQIYDLVKEVPQKAKTLMKKFWPGPLTLIFKKSQKVPYVNTAGMDTVA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCCEEE
IRMPSNTIAHLLIKRAEVPISAPSANVSGKPSPTDASHVIEDLYGKVDVIIDGGKCDVGV
EECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCC
ESTVLDLTEKVPVILRPGAVTLEMLKEVIGNVEVDPSLLKKPKEDLKPKSPGMKYKHYSP
CHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCHHHHHCCHHHCCCCCCCCCEEEECC
NAEVYIVTGDLEKVVKKIQELTEEQLKYGKKVGIMATVQTSTQYEKGEIIVVGDRNRPET
CCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCCHHH
IAKNLFAVLRQFDKKGVDVIFAESFGYDNIGLAIMNRLEKAAGYKEISAEGELP
HHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCCC
>Mature Secondary Structure 
TKIVRVNKNNPEIELIDFAAKVIKEGGLVAFPTETVYGIGANSFNEEAIKKIFIAKGRP
CEEEEECCCCCCEEEHHHHHHHHHCCCEEEECCCCEEECCCCCCCHHHHHHHHHCCCCC
QDNPLIVHIAELEQIYDLVKEVPQKAKTLMKKFWPGPLTLIFKKSQKVPYVNTAGMDTVA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCCEEE
IRMPSNTIAHLLIKRAEVPISAPSANVSGKPSPTDASHVIEDLYGKVDVIIDGGKCDVGV
EECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCC
ESTVLDLTEKVPVILRPGAVTLEMLKEVIGNVEVDPSLLKKPKEDLKPKSPGMKYKHYSP
CHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCHHHHHCCHHHCCCCCCCCCEEEECC
NAEVYIVTGDLEKVVKKIQELTEEQLKYGKKVGIMATVQTSTQYEKGEIIVVGDRNRPET
CCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCCHHH
IAKNLFAVLRQFDKKGVDVIFAESFGYDNIGLAIMNRLEKAAGYKEISAEGELP
HHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]