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The map label for this gene is speA [H]

Identifier: 167038726

GI number: 167038726

Start: 55568

End: 56989

Strand: Direct

Name: speA [H]

Synonym: Teth514_0052

Alternate gene names: 167038726

Gene position: 55568-56989 (Clockwise)

Preceding gene: 167038725

Following gene: 167038727

Centisome position: 2.26

GC content: 34.46

Gene sequence:

>1422_bases
ATGACAGCTCCATTATATAAAACACTTATGGATTATGTAAAAAACCAAATTATACCTTTTCACATGCCAGGTCATAAACA
AGGAAGGACTTTTCCAGAAGAATATCTTGTTAATTTGGCAAAGATTGATCTAACAGAGGTACCAGGACTTGACAATCTTC
ACAATCCTGAAGGTCCCATACTTGAGGCACAAAAACTTGCAGCAAAAGCTTTTGGGGCAAGAGAGTCTTTTTTTCTTGTA
AATGGGACGACATCCGGCATATATGCAGCGATGTACGCAGTTTTAAATCCTGACGATAAAGTGCTTATAATGAGAAATTC
TCACAAATCTGTGTACAATGGCCTTGTACTAACAGGAGCAGTACCTGTCTACATAAACCCGGAAATTGATTATGAAGACG
GTATTCCAATGGGAGTTGATATAAACAAACTGGAAGAATATTTAAAAAAAGATGAGTCTATAAAAGCAGTAGTGATAACT
TATCCCAATTATTACGGATTCTGCAGCGATATCACAGGAATTTCTGACATTGTTCATAAATACAATAAAATTTTAATTGT
AGATGAAGCCCATGGAGCTCACTTTCCTTTTTCTAATAATTTGCCTCTTTCTTCTTTACAGGCAGGATCAGATATTGTGG
TACAGAGTGTCCACAAAACCTTGTCTTCTTTTACTCAAAGTTCTATACTTCATTTGAATTCTGATAGAGTAGATACAAAT
CGACTAAAATATTCTTTAAGCCTTTTTCAATCAACATCTCCTTCCTACCTTCTTATGTCTTCGCTTGACCTTGCAAGAGA
TTATATGGAAAAAGAAGGTAAAAACAGATTAGAAAAAGCGATTATTATTGCTGATTATGCAAGATATGAGATAAACACCA
TTGGGGGAGTAAGGTGTTTAGGAAAAGAAATAGTAGGTAGCTTCGGCATTGTTGACTTTGACAAAACCAAACTCACTGTA
AGTGTAAAGAACATAGGTATAAAGGGGACTGAAGCGGAAAAGTTTTTGAGGGAGAATTTTAATATACAGGTAGAGATGGC
CGATACTTTTAATATACTTGCTATGGTTACATTGGCAGATGATAAAGAAAAGATTGACCTTTTAATAAAGGGGATAAAAG
GGCTTGCAAATGTAAAAAAAGATAAAAAAACAGCTGAAGAAGTAGCAGCTTATCCTGATACTCCAGAAATGGTTTTAAAA
CCTTCTGAAACGGTAAGGCAAAAGACTAAATTAATATCTTTAGAAGAAGCGGAAGGTTGTGTTTCTGCAGACTTTATTAT
CCCTTATCCTCCAGGTGTTCCGCTTATTTGTCCAGGAGAGCGCATAAAAAAAGATATGGTAAAATATATAAATGTATTAT
ATAATAAAGGTATTAAGATATTAGGTCTTAAAAATAACAACCTATTGGTGTGTGAAATATGA

Upstream 100 bases:

>100_bases
GAGGGACATAAAATATGAAAACCGGATATGAATCCGGTTTTCATATTTTTTTATGGTATAATCAAAATAACGAAAAATTA
CGATTACACGGAGGTATTGT

Downstream 100 bases:

>100_bases
AAGGGAAATTTATAAGCTTTGAAGGAATAGATGGATGCGGTAAGACTACTCAGATAAAATTTCTGGAGGAGTATCTTTTA
AAACAGGGTTATAATATTTT

Product: Orn/Lys/Arg decarboxylase, major region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MTAPLYKTLMDYVKNQIIPFHMPGHKQGRTFPEEYLVNLAKIDLTEVPGLDNLHNPEGPILEAQKLAAKAFGARESFFLV
NGTTSGIYAAMYAVLNPDDKVLIMRNSHKSVYNGLVLTGAVPVYINPEIDYEDGIPMGVDINKLEEYLKKDESIKAVVIT
YPNYYGFCSDITGISDIVHKYNKILIVDEAHGAHFPFSNNLPLSSLQAGSDIVVQSVHKTLSSFTQSSILHLNSDRVDTN
RLKYSLSLFQSTSPSYLLMSSLDLARDYMEKEGKNRLEKAIIIADYARYEINTIGGVRCLGKEIVGSFGIVDFDKTKLTV
SVKNIGIKGTEAEKFLRENFNIQVEMADTFNILAMVTLADDKEKIDLLIKGIKGLANVKKDKKTAEEVAAYPDTPEMVLK
PSETVRQKTKLISLEEAEGCVSADFIIPYPPGVPLICPGERIKKDMVKYINVLYNKGIKILGLKNNNLLVCEI

Sequences:

>Translated_473_residues
MTAPLYKTLMDYVKNQIIPFHMPGHKQGRTFPEEYLVNLAKIDLTEVPGLDNLHNPEGPILEAQKLAAKAFGARESFFLV
NGTTSGIYAAMYAVLNPDDKVLIMRNSHKSVYNGLVLTGAVPVYINPEIDYEDGIPMGVDINKLEEYLKKDESIKAVVIT
YPNYYGFCSDITGISDIVHKYNKILIVDEAHGAHFPFSNNLPLSSLQAGSDIVVQSVHKTLSSFTQSSILHLNSDRVDTN
RLKYSLSLFQSTSPSYLLMSSLDLARDYMEKEGKNRLEKAIIIADYARYEINTIGGVRCLGKEIVGSFGIVDFDKTKLTV
SVKNIGIKGTEAEKFLRENFNIQVEMADTFNILAMVTLADDKEKIDLLIKGIKGLANVKKDKKTAEEVAAYPDTPEMVLK
PSETVRQKTKLISLEEAEGCVSADFIIPYPPGVPLICPGERIKKDMVKYINVLYNKGIKILGLKNNNLLVCEI
>Mature_472_residues
TAPLYKTLMDYVKNQIIPFHMPGHKQGRTFPEEYLVNLAKIDLTEVPGLDNLHNPEGPILEAQKLAAKAFGARESFFLVN
GTTSGIYAAMYAVLNPDDKVLIMRNSHKSVYNGLVLTGAVPVYINPEIDYEDGIPMGVDINKLEEYLKKDESIKAVVITY
PNYYGFCSDITGISDIVHKYNKILIVDEAHGAHFPFSNNLPLSSLQAGSDIVVQSVHKTLSSFTQSSILHLNSDRVDTNR
LKYSLSLFQSTSPSYLLMSSLDLARDYMEKEGKNRLEKAIIIADYARYEINTIGGVRCLGKEIVGSFGIVDFDKTKLTVS
VKNIGIKGTEAEKFLRENFNIQVEMADTFNILAMVTLADDKEKIDLLIKGIKGLANVKKDKKTAEEVAAYPDTPEMVLKP
SETVRQKTKLISLEEAEGCVSADFIIPYPPGVPLICPGERIKKDMVKYINVLYNKGIKILGLKNNNLLVCEI

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=560, Percent_Identity=25.3571428571429, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082193, Length=585, Percent_Identity=25.1282051282051, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1786909, Length=592, Percent_Identity=23.9864864864865, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790573, Length=577, Percent_Identity=23.5701906412478, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI221142684, Length=318, Percent_Identity=27.6729559748428, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 52630; Mature: 52498

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPLYKTLMDYVKNQIIPFHMPGHKQGRTFPEEYLVNLAKIDLTEVPGLDNLHNPEGPI
CCCHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHCCHHCCCCCCCCCCCCCCC
LEAQKLAAKAFGARESFFLVNGTTSGIYAAMYAVLNPDDKVLIMRNSHKSVYNGLVLTGA
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHEECCCCCEEEEECCCCHHHCCEEEECE
VPVYINPEIDYEDGIPMGVDINKLEEYLKKDESIKAVVITYPNYYGFCSDITGISDIVHK
EEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHCCHHHHHHHH
YNKILIVDEAHGAHFPFSNNLPLSSLQAGSDIVVQSVHKTLSSFTQSSILHLNSDRVDTN
CCEEEEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCH
RLKYSLSLFQSTSPSYLLMSSLDLARDYMEKEGKNRLEKAIIIADYARYEINTIGGVRCL
HHEEEEEEHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEECCCCCHHHH
GKEIVGSFGIVDFDKTKLTVSVKNIGIKGTEAEKFLRENFNIQVEMADTFNILAMVTLAD
HHHHHCCCCCEEECCCEEEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCEEEEEEEECC
DKEKIDLLIKGIKGLANVKKDKKTAEEVAAYPDTPEMVLKPSETVRQKTKLISLEEAEGC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHEEEEHHCCCC
VSADFIIPYPPGVPLICPGERIKKDMVKYINVLYNKGIKILGLKNNNLLVCEI
EECCEEEECCCCCCEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEC
>Mature Secondary Structure 
TAPLYKTLMDYVKNQIIPFHMPGHKQGRTFPEEYLVNLAKIDLTEVPGLDNLHNPEGPI
CCHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHCCHHCCCCCCCCCCCCCCC
LEAQKLAAKAFGARESFFLVNGTTSGIYAAMYAVLNPDDKVLIMRNSHKSVYNGLVLTGA
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHEECCCCCEEEEECCCCHHHCCEEEECE
VPVYINPEIDYEDGIPMGVDINKLEEYLKKDESIKAVVITYPNYYGFCSDITGISDIVHK
EEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHCCHHHHHHHH
YNKILIVDEAHGAHFPFSNNLPLSSLQAGSDIVVQSVHKTLSSFTQSSILHLNSDRVDTN
CCEEEEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCH
RLKYSLSLFQSTSPSYLLMSSLDLARDYMEKEGKNRLEKAIIIADYARYEINTIGGVRCL
HHEEEEEEHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEECCCCCHHHH
GKEIVGSFGIVDFDKTKLTVSVKNIGIKGTEAEKFLRENFNIQVEMADTFNILAMVTLAD
HHHHHCCCCCEEECCCEEEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCEEEEEEEECC
DKEKIDLLIKGIKGLANVKKDKKTAEEVAAYPDTPEMVLKPSETVRQKTKLISLEEAEGC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHEEEEHHCCCC
VSADFIIPYPPGVPLICPGERIKKDMVKYINVLYNKGIKILGLKNNNLLVCEI
EECCEEEECCCCCCEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]