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The map label for this gene is tadA [H]

Identifier: 167038705

GI number: 167038705

Start: 34883

End: 35329

Strand: Direct

Name: tadA [H]

Synonym: Teth514_0031

Alternate gene names: 167038705

Gene position: 34883-35329 (Clockwise)

Preceding gene: 167038704

Following gene: 167038706

Centisome position: 1.42

GC content: 36.24

Gene sequence:

>447_bases
ATGATTAATAAGTTTATGGAGGCAGCTCTTTTAGAGGCGAAAAAAAGTTACCAATTAGGTGAAGTACCTGTTGGAGCTGT
CATTGTAAAAGAGGGACAAATAATTGGAAGAGGATTTAATCAAAAAGAGTCTACAAATGATGCTACAGCCCATGCAGAGA
TTATAGCGATAAAGGAAGCTTGTAAAACTCTTGGCAGTTGGAGACTTGATGACTGTAGCATGTATGTGACTTTAGAGCCT
TGTCCCATGTGTGCGGGAGCTATTTTAGAAGCTCGCATAAAAAGAGTGTATATAGGGGCAGAAAGTGATAAATCTGGTGC
TGCAGGTACAGTAGTTGATATTTTAAATAACAGCTATTTAGGAAGTAAAACAGAAGTGTATTTTGGAATAATGGAAGAAG
AATGCAAAACTCTTTTAAAAGACTTCTTTGAAAATTTAAGGGAATAG

Upstream 100 bases:

>100_bases
TACTTGACACTTAAATAATTCTCTGATAAAATACCTTTATGCAGAGGACAAATAAAAAGCAAAAATAAGAGTGTAGTTAC
TTTTGCTTGCGGTGGAGTAT

Downstream 100 bases:

>100_bases
GTGCGGAGAGATGGCTGAGTGGTCGAAAGCGCTCGCCTCGAAAGCGAGTGGGCGAATTTTTCGCCTCGTGAGTTCGAATC
TCACTCTCTCCGCCATGAAA

Product: CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MINKFMEAALLEAKKSYQLGEVPVGAVIVKEGQIIGRGFNQKESTNDATAHAEIIAIKEACKTLGSWRLDDCSMYVTLEP
CPMCAGAILEARIKRVYIGAESDKSGAAGTVVDILNNSYLGSKTEVYFGIMEEECKTLLKDFFENLRE

Sequences:

>Translated_148_residues
MINKFMEAALLEAKKSYQLGEVPVGAVIVKEGQIIGRGFNQKESTNDATAHAEIIAIKEACKTLGSWRLDDCSMYVTLEP
CPMCAGAILEARIKRVYIGAESDKSGAAGTVVDILNNSYLGSKTEVYFGIMEEECKTLLKDFFENLRE
>Mature_148_residues
MINKFMEAALLEAKKSYQLGEVPVGAVIVKEGQIIGRGFNQKESTNDATAHAEIIAIKEACKTLGSWRLDDCSMYVTLEP
CPMCAGAILEARIKRVYIGAESDKSGAAGTVVDILNNSYLGSKTEVYFGIMEEECKTLLKDFFENLRE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=151, Percent_Identity=34.4370860927152, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI145693172, Length=144, Percent_Identity=44.4444444444444, Blast_Score=142, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17554608, Length=107, Percent_Identity=44.8598130841121, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17541138, Length=145, Percent_Identity=35.1724137931034, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=106, Percent_Identity=39.622641509434, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325319, Length=144, Percent_Identity=31.25, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=155, Percent_Identity=31.6129032258064, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=36.3013698630137, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16264; Mature: 16264

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKFMEAALLEAKKSYQLGEVPVGAVIVKEGQIIGRGFNQKESTNDATAHAEIIAIKEA
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHH
CKTLGSWRLDDCSMYVTLEPCPMCAGAILEARIKRVYIGAESDKSGAAGTVVDILNNSYL
HHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHCCCCC
GSKTEVYFGIMEEECKTLLKDFFENLRE
CCCCEEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MINKFMEAALLEAKKSYQLGEVPVGAVIVKEGQIIGRGFNQKESTNDATAHAEIIAIKEA
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHH
CKTLGSWRLDDCSMYVTLEPCPMCAGAILEARIKRVYIGAESDKSGAAGTVVDILNNSYL
HHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHCCCCC
GSKTEVYFGIMEEECKTLLKDFFENLRE
CCCCEEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]