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The map label for this gene is ilvH [H]

Identifier: 167038687

GI number: 167038687

Start: 15127

End: 15630

Strand: Direct

Name: ilvH [H]

Synonym: Teth514_0012

Alternate gene names: 167038687

Gene position: 15127-15630 (Clockwise)

Preceding gene: 167038685

Following gene: 167038688

Centisome position: 0.62

GC content: 35.12

Gene sequence:

>504_bases
TTGCACATTATATCTGTCCTTGTGAACAATCATCCAGGAGTCTTGTCAAGGGTAGTAGGTCTTTTTTCAAGGAGAGGCTA
CAATATTGAAAGCCTTGCAGTAGGAACGACTGAAAGAGAAGATGTATCCAGAATAACTTTGACGGTGGGAGGAGATGATT
ACACCGTCACACAGATGATAAGGCAACTTAATAAACTTATAGATGTGTTGAAAGTACAAAACATAGGAGCAAGAGATAAT
GTTTCTCGAGAATTGCTGTTAGTTAAAGTAGGTTACGATTCAAATACAAGGGATGACATAATGCATATTGTAGATACTTT
TAGAGCAAAAGTTATAGACATTTCCATCGACTCATTAATCGTAGAACTTACCGGAGATAGTGAAAAGATAAACGCTTTTA
TAAATTTAATTAATAAGTTTGAGGTAAAAGAACTTGTCAGGACAGGACTTGTATCTTTAGAGAGAGGCAATAAAACACTA
AAAGAATATGAGGGGGAATTATAA

Upstream 100 bases:

>100_bases
ATTGCCGTGAGGTAATAGCGAAAACAGGTGGTACCGCGTGGAGAAAATCCTCGCCCTGTAATTTAGGGCGGGGATTGATT
TTTATATAGGGGGTGATAAT

Downstream 100 bases:

>100_bases
TGGCAAAGATGTATTATGACAAGGATGCAGATTTGAATTTGCTTAAAAACAAGAAAATCGCAATAATAGGTTTTGGAAGT
CAAGGTCATGCTCATGCACT

Product: acetolactate synthase, small subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MHIISVLVNNHPGVLSRVVGLFSRRGYNIESLAVGTTEREDVSRITLTVGGDDYTVTQMIRQLNKLIDVLKVQNIGARDN
VSRELLLVKVGYDSNTRDDIMHIVDTFRAKVIDISIDSLIVELTGDSEKINAFINLINKFEVKELVRTGLVSLERGNKTL
KEYEGEL

Sequences:

>Translated_167_residues
MHIISVLVNNHPGVLSRVVGLFSRRGYNIESLAVGTTEREDVSRITLTVGGDDYTVTQMIRQLNKLIDVLKVQNIGARDN
VSRELLLVKVGYDSNTRDDIMHIVDTFRAKVIDISIDSLIVELTGDSEKINAFINLINKFEVKELVRTGLVSLERGNKTL
KEYEGEL
>Mature_167_residues
MHIISVLVNNHPGVLSRVVGLFSRRGYNIESLAVGTTEREDVSRITLTVGGDDYTVTQMIRQLNKLIDVLKVQNIGARDN
VSRELLLVKVGYDSNTRDDIMHIVDTFRAKVIDISIDSLIVELTGDSEKINAFINLINKFEVKELVRTGLVSLERGNKTL
KEYEGEL

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=161, Percent_Identity=41.6149068322981, Blast_Score=129, Evalue=9e-32,
Organism=Escherichia coli, GI1790103, Length=71, Percent_Identity=46.4788732394366, Blast_Score=66, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319837, Length=203, Percent_Identity=30.0492610837438, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18742; Mature: 18742

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIISVLVNNHPGVLSRVVGLFSRRGYNIESLAVGTTEREDVSRITLTVGGDDYTVTQMI
CEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEECCCCHHHHHHH
RQLNKLIDVLKVQNIGARDNVSRELLLVKVGYDSNTRDDIMHIVDTFRAKVIDISIDSLI
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEHHHEE
VELTGDSEKINAFINLINKFEVKELVRTGLVSLERGNKTLKEYEGEL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
>Mature Secondary Structure
MHIISVLVNNHPGVLSRVVGLFSRRGYNIESLAVGTTEREDVSRITLTVGGDDYTVTQMI
CEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEECCCCHHHHHHH
RQLNKLIDVLKVQNIGARDNVSRELLLVKVGYDSNTRDDIMHIVDTFRAKVIDISIDSLI
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHEEEEEEHHHEE
VELTGDSEKINAFINLINKFEVKELVRTGLVSLERGNKTLKEYEGEL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]