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The map label for this gene is xseA [H]

Identifier: 163844893

GI number: 163844893

Start: 732806

End: 734341

Strand: Reverse

Name: xseA [H]

Synonym: BSUIS_B0756

Alternate gene names: 163844893

Gene position: 734341-732806 (Counterclockwise)

Preceding gene: 163844894

Following gene: 163844890

Centisome position: 52.42

GC content: 64.19

Gene sequence:

>1536_bases
ATGGCCTCCGATTCGAGTTTTCCCGGCGCATCGTCGAATGTGGCCGAGTATAGCGTGTCCGAGATTTCCGGCGCTTTGAA
GCGCACGGTTGAGGACACGTTCGGCCATGTGCGTGTGCGCGGCGAGATTTCCGGCTATCGCGGCCCGCATTCTTCCGGCC
ATGCCTATTTTGCGCTGAAGGATGACCGTGCCCGGCTTGAAGCCGTGATCTGGCGCGGCTCGATGAGCCGCCTTCGCTTC
CGCCCCGAAGAGGGCATGGAGGTGATCGCCACCGGCAAGCTCACCACCTATCCCGGTTCATCCAAATATCAGATCGTCAT
CGAGCAGATGGAACCCGCCGGCGCGGGCGCGCTGATGGCGCTTCTGGAGGAGCGCAAGCAGCGCCTGGCGGCAGAAGGCC
TGTTCGATCCTGCTCTGAAACAGCTTCTGCCCTTCATGCCGCGCGTCATCGGCGTGGTGACATCTCCCACCGGCGCGGTC
ATCCGCGATATCATCCATCGCATTTCCGATCGTTATCCGCTGCGCGTGATCGTCTGGCCGGTGCGCGTGCAGGGCGATAC
CTGCGGGCCTGAAGTGGCAACGGCGGTGAACGGCTTCAACACCCTGCCGGATGACGGCCCCATTCTGCGCCCCGATGTGC
TGATCGTGGCGCGCGGCGGCGGCAGTCTGGAAGATCTCTGGGGCTTTAACGATGAAATCGTCGTGCGGGCGGTCGCAGCT
TCCCATATTCCCGTTATCTCGGCGGTCGGGCATGAAACCGACTGGACGCTGATAGATCTTGCCGCCGACATGCGCGCGCC
GACCCCCACCGGTGCTGCGGAAATGGCGGTGCCGGTGAAGGCTGATCTTCAGGCCTCACTTGCCAGCCAGTCGGCGCGGC
TTTCTTCCGCCATGTCGCGCTTTTTCGACCAGAAGCGACAGGCGCATCGTGCTGCCGCGCGCGCCATGCCCTCTGCCGAC
CAGTTGCTGGCCCTGCCGCGCCGCCGGTTCGATGAAGCGGCCTCGCGGCTTACCCGCGCACTTTTCGTCAATACGCAGAA
AAAGCGCGTCCATTTCGATGGTCATGCCCGGCAATTGTCGCCCCGGCTTTTACAGCGGCGGCTTGTGGAGCTGGAACGCG
GTGTGACGATGCTGGGCCAGCGCCTGCCGCGCGCGCTGGAAGCCTTTCTGCGCGAGCGCCGGACGGCTTTCACCCATCGC
GCCAACCGGCTTTCGCCGGAACCCATATTGCGCCGCACACGGCTGACGGGCTCGACCCTCGAACAGCTCGACCGCCGCCG
CGATCAGGCCGTGCGGCTTCTGATCGAGCGTGTGAAGCGGCGCAGTCAAGAACTCGACCGGTTGATGCGCACGCTTTCTT
ATGAAAGCGTGCTGGAACGCGGCTTTGCTGTTGTATTCGATGCGCAGGGCAAGCCCGTCAAGCAGGCGGCGGCTGTGTCG
CCAGGCGATGCGCTGTCTGTCCGGTTCCGCGACGGTGATGTCGGGGTTGTCGCGCGCGCGGGACTCACAATCCCCGATCC
GACCAAAGGCCAGTAA

Upstream 100 bases:

>100_bases
TGCGCACCAATGAATTGTTGCCCGGCTGGTGAACAGTGCGTAATTCGCCGCGCGGCTGCTTGACCGCCTGCGCCCACTGG
TAGCCTATAACGGGATGAGC

Downstream 100 bases:

>100_bases
GTCTCAAGCTGAAAAAAGGCGCGATCATCGCGCCCTTTTCCATTTTGTGACATCGGAACGCTTCTTCAATAGACATATTC
GAGGAAGATCGGATCCACCG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALKDDRARLEAVIWRGSMSRLRF
RPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMALLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAV
IRDIIHRISDRYPLRVIVWPVRVQGDTCGPEVATAVNGFNTLPDDGPILRPDVLIVARGGGSLEDLWGFNDEIVVRAVAA
SHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSRFFDQKRQAHRAAARAMPSAD
QLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLSPRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHR
ANRLSPEPILRRTRLTGSTLEQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVS
PGDALSVRFRDGDVGVVARAGLTIPDPTKGQ

Sequences:

>Translated_511_residues
MASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALKDDRARLEAVIWRGSMSRLRF
RPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMALLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAV
IRDIIHRISDRYPLRVIVWPVRVQGDTCGPEVATAVNGFNTLPDDGPILRPDVLIVARGGGSLEDLWGFNDEIVVRAVAA
SHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSRFFDQKRQAHRAAARAMPSAD
QLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLSPRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHR
ANRLSPEPILRRTRLTGSTLEQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVS
PGDALSVRFRDGDVGVVARAGLTIPDPTKGQ
>Mature_510_residues
ASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALKDDRARLEAVIWRGSMSRLRFR
PEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMALLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAVI
RDIIHRISDRYPLRVIVWPVRVQGDTCGPEVATAVNGFNTLPDDGPILRPDVLIVARGGGSLEDLWGFNDEIVVRAVAAS
HIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSRFFDQKRQAHRAAARAMPSADQ
LLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLSPRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHRA
NRLSPEPILRRTRLTGSTLEQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVSP
GDALSVRFRDGDVGVVARAGLTIPDPTKGQ

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=487, Percent_Identity=35.9342915811088, Blast_Score=259, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 56349; Mature: 56218

Theoretical pI: Translated: 10.87; Mature: 10.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEEEC
DDRARLEAVIWRGSMSRLRFRPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMA
CCHHHHHHHHCCCCHHHHCCCCCCCCEEEEECEEEECCCCCCEEEEEEECCCCCHHHHHH
LLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAVIRDIIHRISDRYPLRVIVWP
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEE
VRVQGDTCGPEVATAVNGFNTLPDDGPILRPDVLIVARGGGSLEDLWGFNDEIVVRAVAA
EEECCCCCCHHHHHHHCCCCCCCCCCCEECCCEEEEECCCCCHHHHCCCCCHHHHHHHHH
SHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSR
CCCCEEHCCCCCCCCEEEEEHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHH
FFDQKRQAHRAAARAMPSADQLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCHHHCC
PRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHRANRLSPEPILRRTRLTGSTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
EQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHCCC
PGDALSVRFRDGDVGVVARAGLTIPDPTKGQ
CCCEEEEEEECCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
ASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEEEC
DDRARLEAVIWRGSMSRLRFRPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMA
CCHHHHHHHHCCCCHHHHCCCCCCCCEEEEECEEEECCCCCCEEEEEEECCCCCHHHHHH
LLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAVIRDIIHRISDRYPLRVIVWP
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEE
VRVQGDTCGPEVATAVNGFNTLPDDGPILRPDVLIVARGGGSLEDLWGFNDEIVVRAVAA
EEECCCCCCHHHHHHHCCCCCCCCCCCEECCCEEEEECCCCCHHHHCCCCCHHHHHHHHH
SHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSR
CCCCEEHCCCCCCCCEEEEEHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHH
FFDQKRQAHRAAARAMPSADQLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCHHHCC
PRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHRANRLSPEPILRRTRLTGSTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
EQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHCCC
PGDALSVRFRDGDVGVVARAGLTIPDPTKGQ
CCCEEEEEEECCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA