Click here to switch to the map view.

The map label for this gene is hexR [H]

Identifier: 163844875

GI number: 163844875

Start: 714940

End: 715821

Strand: Reverse

Name: hexR [H]

Synonym: BSUIS_B0736

Alternate gene names: 163844875

Gene position: 715821-714940 (Counterclockwise)

Preceding gene: 163844876

Following gene: 163844874

Centisome position: 51.1

GC content: 61.79

Gene sequence:

>882_bases
ATGAGCAAGGTTGCCGATATCATAACGCGGCTGCATGTCGTGGCGCAGGAAGGGTCGAAATCCGACCGGCGGCTCGCCGG
GCTGGTTCTGGCCGATCCCCATTATGCTTCCAAGGCGGCAATCTCGGAGATCGCCGCGCGGGCAGGGGTCAGCGAGCCGA
CGGTCACGCGCTTTTGCCGTGCGCTTGGCTGCGACGGTGTGCGCGATTTCAAGTTTTTTCTGGCGCAGGCGCTGGCCATT
GGCGGACAATATCTGACCGCTGAAATTCCCGCCCGCGACGTGCGTGAAAGCCGCATTGCCACCGCAGTCACTGATGCTGC
AATCGCTGCCATCCAGCGCGCGGGCGACGGGGTGGATATGGGGGTTCTGATGAAGGTTGCCGAACGGCTTGCCGCTGGCG
GTCCCGTGCTTTGCCTCGGTTCCGGCGGCATGTCGTCCATGCTGGCGACGGAAATGGAAAACCGCCTGTTCCGCCTCGGC
ATTCCGGTCAATGCGCAGGTGGATGGGCAGTTGCAGCGCATGTATGCCGCCGTCACCACGCATGAGACGACCGTGCTTGC
CTTTTCCGTGTCGGGTTTTGCGCGCTCTGTCGTGGAGGCCGTGCTGGTTGCGCGGCAATATGGAGCCGAAACGGTGGCTA
TCACCGCCGCCGGTTCCGATCTCGCCAGGGCTGCGGATATGCTCATTCCGTTCCAGCCCAACGAAGACGGCAATATCTAC
AAACCCACCTCGGCACGTTACGGGCTTCTTGCCATTCTCGATATGATTGCAACCGCCGCTGCCGAAGCGCGAGGGCCGAA
GGTGCTGGAAAGCCTGCGCCGCATCAAACACAGCCTCAATACACTTACCATAGACGATCCGCGTCTACCGCTTGGAGACT
GA

Upstream 100 bases:

>100_bases
CGGATACAGCTTGCGCCGGGCGAGCAGGTTCCTGTAACGGCTGGGAGCGAACATATTCATCTCTTTGATAAGGAAAGCGG
TTTGCCGCTTTGAGCTTTTC

Downstream 100 bases:

>100_bases
CTTTATGCCCATTAAGCCTAAAAACATCTGCGAGGTGGATACACCTGCCATTCTGGTTGATGTTGATCGTGTGGTTGCAA
ATATCGAAAAGGCACAGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSKVADIITRLHVVAQEGSKSDRRLAGLVLADPHYASKAAISEIAARAGVSEPTVTRFCRALGCDGVRDFKFFLAQALAI
GGQYLTAEIPARDVRESRIATAVTDAAIAAIQRAGDGVDMGVLMKVAERLAAGGPVLCLGSGGMSSMLATEMENRLFRLG
IPVNAQVDGQLQRMYAAVTTHETTVLAFSVSGFARSVVEAVLVARQYGAETVAITAAGSDLARAADMLIPFQPNEDGNIY
KPTSARYGLLAILDMIATAAAEARGPKVLESLRRIKHSLNTLTIDDPRLPLGD

Sequences:

>Translated_293_residues
MSKVADIITRLHVVAQEGSKSDRRLAGLVLADPHYASKAAISEIAARAGVSEPTVTRFCRALGCDGVRDFKFFLAQALAI
GGQYLTAEIPARDVRESRIATAVTDAAIAAIQRAGDGVDMGVLMKVAERLAAGGPVLCLGSGGMSSMLATEMENRLFRLG
IPVNAQVDGQLQRMYAAVTTHETTVLAFSVSGFARSVVEAVLVARQYGAETVAITAAGSDLARAADMLIPFQPNEDGNIY
KPTSARYGLLAILDMIATAAAEARGPKVLESLRRIKHSLNTLTIDDPRLPLGD
>Mature_292_residues
SKVADIITRLHVVAQEGSKSDRRLAGLVLADPHYASKAAISEIAARAGVSEPTVTRFCRALGCDGVRDFKFFLAQALAIG
GQYLTAEIPARDVRESRIATAVTDAAIAAIQRAGDGVDMGVLMKVAERLAAGGPVLCLGSGGMSSMLATEMENRLFRLGI
PVNAQVDGQLQRMYAAVTTHETTVLAFSVSGFARSVVEAVLVARQYGAETVAITAAGSDLARAADMLIPFQPNEDGNIYK
PTSARYGLLAILDMIATAAAEARGPKVLESLRRIKHSLNTLTIDDPRLPLGD

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=288, Percent_Identity=31.9444444444444, Blast_Score=150, Evalue=8e-38,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30952; Mature: 30821

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00356 HTH_LACI_1 ; PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVADIITRLHVVAQEGSKSDRRLAGLVLADPHYASKAAISEIAARAGVSEPTVTRFCR
CCHHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHH
ALGCDGVRDFKFFLAQALAIGGQYLTAEIPARDVRESRIATAVTDAAIAAIQRAGDGVDM
HHCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
GVLMKVAERLAAGGPVLCLGSGGMSSMLATEMENRLFRLGIPVNAQVDGQLQRMYAAVTT
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHH
HETTVLAFSVSGFARSVVEAVLVARQYGAETVAITAAGSDLARAADMLIPFQPNEDGNIY
CCEEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHEECCCCCCCCCEE
KPTSARYGLLAILDMIATAAAEARGPKVLESLRRIKHSLNTLTIDDPRLPLGD
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEECCCCCCCCC
>Mature Secondary Structure 
SKVADIITRLHVVAQEGSKSDRRLAGLVLADPHYASKAAISEIAARAGVSEPTVTRFCR
CHHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHH
ALGCDGVRDFKFFLAQALAIGGQYLTAEIPARDVRESRIATAVTDAAIAAIQRAGDGVDM
HHCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
GVLMKVAERLAAGGPVLCLGSGGMSSMLATEMENRLFRLGIPVNAQVDGQLQRMYAAVTT
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHH
HETTVLAFSVSGFARSVVEAVLVARQYGAETVAITAAGSDLARAADMLIPFQPNEDGNIY
CCEEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHEECCCCCCCCCEE
KPTSARYGLLAILDMIATAAAEARGPKVLESLRRIKHSLNTLTIDDPRLPLGD
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 1704005; 7567469 [H]