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The map label for this gene is prc

Identifier: 16273555

GI number: 16273555

Start: 1736086

End: 1738173

Strand: Reverse

Name: prc

Synonym: HI1668

Alternate gene names: 16273555

Gene position: 1738173-1736086 (Counterclockwise)

Preceding gene: 16273557

Following gene: 16273554

Centisome position: 94.97

GC content: 34.96

Gene sequence:

>2088_bases
ATGGTTATGAAATTTAAAATGTCAAAAAATGTGATTTGTTATACGTGGTTATCGGTGTGTTTGAGCAGTGCAATTCCTGC
ATTTGCTGTACAACCTACATTAAAACCAAGTGACATTAGTATTCCAGCGATAAGTGAAGAAAGCCAGTTGGCAACTAAGC
GTGCAACGACAAGATTAACTCAATCCCATTATCGTAAGATTAAATTAGATGATGATTTTTCCGAGAAAATTTTTGATCGT
TATATTAAAAATTTAGATTTTAACCACAATACTTTTTTGCAGTCTGATATAGACGAACTTCGTCAAAAATATGGTACTAA
GTTAGATGAACAGTTGAATCAAGGCGATCTTTCTGCAGCGTTTGACATTTATGATGTAATGATGAAACGTCGCTATGAAC
GTTATACTTATGCGTTATCTTTATTAGATAAAGAGCCTGATTTAAATGGTCAAGATCAAATTGAAATTGATCGTGAAAAA
GCGGCTGCGCCACAAACTGAAGCTGATGCAAATAAACTTTGGGATGCTCGTGTAAAAAATGACATTATTAATCTTAAATT
AAAAGATAAAAAATGGTCAGAAATCAAAGCAAAGCTTACAAAACGCTATAATTTAGCCATTCGTCGTTTAACGCAAACAA
AAGCAGACGATATTGTTCAAATTTATTTGAATGCTTTTGCGCGTGAAATTGATCCTCACACCAGTTATCTTTCCCCAAGA
ACAGCAAAAAGTTTTAATGAAAGTATAAATCTTTCTTTGGAAGGCATTGGGACTACTTTACAATCAGAAGATGATGAAAT
TAGCATCAAATCTCTTGTACCTGGTGCGCCAGCGGAACGTAGTAAAAAGCTGCATCCTGGGGATAAAATCATTGGTGTTG
GGCAAGCAACAGGCGATATTGAAGACGTTGTTGGTTGGCGTTTAGAAGATTTGGTAGAAAAAATTAAAGGGAAAAAAGGC
ACTAAAGTTCGCTTAGAAATTGAGCCTGCTAAAGGGGGAAAATCACGTATTATTACTTTGGTTCGTGATAAAGTCCGTAT
TGAAGATCAAGCGGCTAAACTAACCTTTGAAAAAGTGTCAGGAAAAAACATTGCGGTAATAAAAATTCCAAGTTTTTATA
TTGGATTAACCGAAGATGTCAAAAAACTACTGGTTAAATTAGAAAATCAAAAAGCTGAGGCTCTTATTGTTGATTTACGT
GAAAATGGCGGTGGTGCATTAACGGAAGCGGTGGCGTTAAGTGGTTTATTTATTACCGATGGCCCTGTTGTGCAGGTTCG
CGATGCTTATCAGCGTATTCGTGTTCATGAAGATGATGATGCTACGCAACAATATAAGGGGTTATTATTTGTGATGATTA
ATCGTTACAGTGCTTCCGCATCAGAAATTTTTGCTGCAGCAATGCAAGATTATCGTCGAGGTATTATCATCGGGCAAAAT
ACTTTTGGTAAAGGTACGGTGCAACAGAGTCGTTCGTTAAATTTTATCTATGATTTAGATCAGAGTCCGTTGGGTGTTTT
GCAATATACTATTCAAAAATTTTATCGCGTTAATGGTGGTTCAACCCAATTAAAAGGTGTTGCAGCCGATATTAATTTTC
CTGAAATTATAGATGCGAAAGAATATGGGGAAGATAAAGAAGATAATGCGCTTGCTTGGGATAAAATCCCATCAGCGAGT
TATATGGAAGTAGGAAATATCAATTATATTGATAATGCAGTAAATATTCTAAATGAAAAACATCTTGCTCGTATTGCTAA
AGATCCTGAATTTGTTGCATTGAATGAAGAATTGAAAGTGCGAAATGAACGCCGAGATCGAAAATTTCTATCATTGAATT
ATAAAATGCGTAAAGCAGAGAATGATAAAGATGATGCAAGACGTTTAAAAGATTTGAACGAACGTTTTAAACGTGAGGGT
AAGAAAGCATTGAAAGATATTGATGATTTGCCGAAAGATTACGAAGCACCAGATTTCTTCTTAAAAGAAGCTGAAAAAAT
AGCAGCTGATTTCGTTATTTTTAATTCAGATCAGAAAATTAATCAAGCAAACGGCCTATCCGAAGCAAAAACGGAAAGTA
AAAAATAA

Upstream 100 bases:

>100_bases
AGTATTAAAAGATTCAGCACGTGTTGAACTTGAAAACGGTTTGATTATGAACGTTGCTGCAGATCGTTTATTTGCTTAAT
AAATAAAAATTGACTCGGAA

Downstream 100 bases:

>100_bases
ATACTAAATGGTTTTGACCGCACTTTGTTTGAGAAAAGCAACAAGTGCGGTGATTTTAATAAAGGTTTAGGAAATGGTAG
TGTTTAAAAGCACCTTAAAG

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; Protease Re

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MVMKFKMSKNVICYTWLSVCLSSAIPAFAVQPTLKPSDISIPAISEESQLATKRATTRLTQSHYRKIKLDDDFSEKIFDR
YIKNLDFNHNTFLQSDIDELRQKYGTKLDEQLNQGDLSAAFDIYDVMMKRRYERYTYALSLLDKEPDLNGQDQIEIDREK
AAAPQTEADANKLWDARVKNDIINLKLKDKKWSEIKAKLTKRYNLAIRRLTQTKADDIVQIYLNAFAREIDPHTSYLSPR
TAKSFNESINLSLEGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDIEDVVGWRLEDLVEKIKGKKG
TKVRLEIEPAKGGKSRIITLVRDKVRIEDQAAKLTFEKVSGKNIAVIKIPSFYIGLTEDVKKLLVKLENQKAEALIVDLR
ENGGGALTEAVALSGLFITDGPVVQVRDAYQRIRVHEDDDATQQYKGLLFVMINRYSASASEIFAAAMQDYRRGIIIGQN
TFGKGTVQQSRSLNFIYDLDQSPLGVLQYTIQKFYRVNGGSTQLKGVAADINFPEIIDAKEYGEDKEDNALAWDKIPSAS
YMEVGNINYIDNAVNILNEKHLARIAKDPEFVALNEELKVRNERRDRKFLSLNYKMRKAENDKDDARRLKDLNERFKREG
KKALKDIDDLPKDYEAPDFFLKEAEKIAADFVIFNSDQKINQANGLSEAKTESKK

Sequences:

>Translated_695_residues
MVMKFKMSKNVICYTWLSVCLSSAIPAFAVQPTLKPSDISIPAISEESQLATKRATTRLTQSHYRKIKLDDDFSEKIFDR
YIKNLDFNHNTFLQSDIDELRQKYGTKLDEQLNQGDLSAAFDIYDVMMKRRYERYTYALSLLDKEPDLNGQDQIEIDREK
AAAPQTEADANKLWDARVKNDIINLKLKDKKWSEIKAKLTKRYNLAIRRLTQTKADDIVQIYLNAFAREIDPHTSYLSPR
TAKSFNESINLSLEGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDIEDVVGWRLEDLVEKIKGKKG
TKVRLEIEPAKGGKSRIITLVRDKVRIEDQAAKLTFEKVSGKNIAVIKIPSFYIGLTEDVKKLLVKLENQKAEALIVDLR
ENGGGALTEAVALSGLFITDGPVVQVRDAYQRIRVHEDDDATQQYKGLLFVMINRYSASASEIFAAAMQDYRRGIIIGQN
TFGKGTVQQSRSLNFIYDLDQSPLGVLQYTIQKFYRVNGGSTQLKGVAADINFPEIIDAKEYGEDKEDNALAWDKIPSAS
YMEVGNINYIDNAVNILNEKHLARIAKDPEFVALNEELKVRNERRDRKFLSLNYKMRKAENDKDDARRLKDLNERFKREG
KKALKDIDDLPKDYEAPDFFLKEAEKIAADFVIFNSDQKINQANGLSEAKTESKK
>Mature_695_residues
MVMKFKMSKNVICYTWLSVCLSSAIPAFAVQPTLKPSDISIPAISEESQLATKRATTRLTQSHYRKIKLDDDFSEKIFDR
YIKNLDFNHNTFLQSDIDELRQKYGTKLDEQLNQGDLSAAFDIYDVMMKRRYERYTYALSLLDKEPDLNGQDQIEIDREK
AAAPQTEADANKLWDARVKNDIINLKLKDKKWSEIKAKLTKRYNLAIRRLTQTKADDIVQIYLNAFAREIDPHTSYLSPR
TAKSFNESINLSLEGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDIEDVVGWRLEDLVEKIKGKKG
TKVRLEIEPAKGGKSRIITLVRDKVRIEDQAAKLTFEKVSGKNIAVIKIPSFYIGLTEDVKKLLVKLENQKAEALIVDLR
ENGGGALTEAVALSGLFITDGPVVQVRDAYQRIRVHEDDDATQQYKGLLFVMINRYSASASEIFAAAMQDYRRGIIIGQN
TFGKGTVQQSRSLNFIYDLDQSPLGVLQYTIQKFYRVNGGSTQLKGVAADINFPEIIDAKEYGEDKEDNALAWDKIPSAS
YMEVGNINYIDNAVNILNEKHLARIAKDPEFVALNEELKVRNERRDRKFLSLNYKMRKAENDKDDARRLKDLNERFKREG
KKALKDIDDLPKDYEAPDFFLKEAEKIAADFVIFNSDQKINQANGLSEAKTESKK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1788134, Length=665, Percent_Identity=52.3308270676692, Blast_Score=665, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRC_HAEIN (P45306)

Other databases:

- EMBL:   L42023
- PIR:   F64135
- RefSeq:   NP_439810.1
- ProteinModelPortal:   P45306
- SMR:   P45306
- MEROPS:   S41.001
- GeneID:   950859
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1668
- NMPDR:   fig|71421.1.peg.1582
- TIGR:   HI_1668
- HOGENOM:   HBG297025
- OMA:   GHVQYTI
- ProtClustDB:   PRK11186
- BioCyc:   HINF71421:HI_1668-MONOMER
- BRENDA:   3.4.21.102
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992
- SMART:   SM00228
- SMART:   SM00245
- TIGRFAMs:   TIGR00225

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41; SSF50156 PDZ

EC number: =3.4.21.102

Molecular weight: Translated: 78871; Mature: 78871

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS50106 PDZ

Important sites: ACT_SITE 459-459 ACT_SITE 470-470 ACT_SITE 484-484

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMKFKMSKNVICYTWLSVCLSSAIPAFAVQPTLKPSDISIPAISEESQLATKRATTRLT
CEEEEECCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QSHYRKIKLDDDFSEKIFDRYIKNLDFNHNTFLQSDIDELRQKYGTKLDEQLNQGDLSAA
HHHCEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHH
FDIYDVMMKRRYERYTYALSLLDKEPDLNGQDQIEIDREKAAAPQTEADANKLWDARVKN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHCCCCCCCCCHHHHHHHHHCC
DIINLKLKDKKWSEIKAKLTKRYNLAIRRLTQTKADDIVQIYLNAFAREIDPHTSYLSPR
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
TAKSFNESINLSLEGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDI
HHHHCCCCEEEEEEECCCCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCH
EDVVGWRLEDLVEKIKGKKGTKVRLEIEPAKGGKSRIITLVRDKVRIEDQAAKLTFEKVS
HHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHEEEEHHHHHHCCHHHHHEEHEECC
GKNIAVIKIPSFYIGLTEDVKKLLVKLENQKAEALIVDLRENGGGALTEAVALSGLFITD
CCEEEEEEECCEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCEEECC
GPVVQVRDAYQRIRVHEDDDATQQYKGLLFVMINRYSASASEIFAAAMQDYRRGIIIGQN
CCEEEEHHHHHHCCCCCCCCHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEECC
TFGKGTVQQSRSLNFIYDLDQSPLGVLQYTIQKFYRVNGGSTQLKGVAADINFPEIIDAK
CCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHCCHH
EYGEDKEDNALAWDKIPSASYMEVGNINYIDNAVNILNEKHLARIAKDPEFVALNEELKV
HCCCCCCCCCEEECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHH
RNERRDRKFLSLNYKMRKAENDKDDARRLKDLNERFKREGKKALKDIDDLPKDYEAPDFF
HHHHHCCCEEEECEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LKEAEKIAADFVIFNSDQKINQANGLSEAKTESKK
HHHHHHHHEEEEEECCCCCCHHHCCCCHHHHCCCC
>Mature Secondary Structure
MVMKFKMSKNVICYTWLSVCLSSAIPAFAVQPTLKPSDISIPAISEESQLATKRATTRLT
CEEEEECCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QSHYRKIKLDDDFSEKIFDRYIKNLDFNHNTFLQSDIDELRQKYGTKLDEQLNQGDLSAA
HHHCEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHH
FDIYDVMMKRRYERYTYALSLLDKEPDLNGQDQIEIDREKAAAPQTEADANKLWDARVKN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHCCCCCCCCCHHHHHHHHHCC
DIINLKLKDKKWSEIKAKLTKRYNLAIRRLTQTKADDIVQIYLNAFAREIDPHTSYLSPR
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
TAKSFNESINLSLEGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDI
HHHHCCCCEEEEEEECCCCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCH
EDVVGWRLEDLVEKIKGKKGTKVRLEIEPAKGGKSRIITLVRDKVRIEDQAAKLTFEKVS
HHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCHHEEEEHHHHHHCCHHHHHEEHEECC
GKNIAVIKIPSFYIGLTEDVKKLLVKLENQKAEALIVDLRENGGGALTEAVALSGLFITD
CCEEEEEEECCEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCEEECC
GPVVQVRDAYQRIRVHEDDDATQQYKGLLFVMINRYSASASEIFAAAMQDYRRGIIIGQN
CCEEEEHHHHHHCCCCCCCCHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEECC
TFGKGTVQQSRSLNFIYDLDQSPLGVLQYTIQKFYRVNGGSTQLKGVAADINFPEIIDAK
CCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHCCHH
EYGEDKEDNALAWDKIPSASYMEVGNINYIDNAVNILNEKHLARIAKDPEFVALNEELKV
HCCCCCCCCCEEECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHH
RNERRDRKFLSLNYKMRKAENDKDDARRLKDLNERFKREGKKALKDIDDLPKDYEAPDFF
HHHHHCCCEEEECEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LKEAEKIAADFVIFNSDQKINQANGLSEAKTESKK
HHHHHHHHEEEEEECCCCCCHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800