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The map label for this gene is merR2

Identifier: 16273513

GI number: 16273513

Start: 1689316

End: 1689723

Strand: Direct

Name: merR2

Synonym: HI1623

Alternate gene names: 16273513

Gene position: 1689316-1689723 (Clockwise)

Preceding gene: 16273507

Following gene: 16273516

Centisome position: 92.31

GC content: 35.54

Gene sequence:

>408_bases
ATGAAAATTGGAGCACTTGCTAAAGCCCTAGGCTGTACCGTAGAAACCATCCGTTATTATGAACAACAAGGTTTAATCCC
GCCCCCAAAACGCACTTCAGGCAATTTTCGGCAATATAATGAAGAACATTTGCAACGTTTATCATTTATTTGTAACTGCC
GAAATTTAGATATTTCATTAAGTGAAATAAAAAGCCTACTGAATTTGGAAAATGCCTCCAAACAACAAGCAGAAGAAATT
AATCGTGTGTTAGATAAACACATTAAAGAGGTGGCAACAAGGATTCACGAACTCGCCCATTTACGGATGAAATTAATTGA
ATTACGTGAAAAAACAGTCTCGAATGATGAAGATCCAATGAAATTGCTATTGCAACATAGTGGCGTAAAATTTGTGCGAT
TAAAATAA

Upstream 100 bases:

>100_bases
TTCAATTCCATTTTGGATACTCCTTGTTTGTTTAAGAAAATCTAGGCGTATGATAAAATATGAAGTAACTTTAGAATCAA
GTCATTTTTTAAGGAAATTG

Downstream 100 bases:

>100_bases
CCGCACTTTTAGATTATGGCTGACTAGATAAACGCTGTTTTGCTTCCTTATTGCCTAATTCAGCGGCTTTCTTCAGCCAT
TCCAATGATTTTTTCAGGTT

Product: mercuric resistance operon regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MKIGALAKALGCTVETIRYYEQQGLIPPPKRTSGNFRQYNEEHLQRLSFICNCRNLDISLSEIKSLLNLENASKQQAEEI
NRVLDKHIKEVATRIHELAHLRMKLIELREKTVSNDEDPMKLLLQHSGVKFVRLK

Sequences:

>Translated_135_residues
MKIGALAKALGCTVETIRYYEQQGLIPPPKRTSGNFRQYNEEHLQRLSFICNCRNLDISLSEIKSLLNLENASKQQAEEI
NRVLDKHIKEVATRIHELAHLRMKLIELREKTVSNDEDPMKLLLQHSGVKFVRLK
>Mature_135_residues
MKIGALAKALGCTVETIRYYEQQGLIPPPKRTSGNFRQYNEEHLQRLSFICNCRNLDISLSEIKSLLNLENASKQQAEEI
NRVLDKHIKEVATRIHELAHLRMKLIELREKTVSNDEDPMKLLLQHSGVKFVRLK

Specific function: Transcriptional regulator

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1786695, Length=128, Percent_Identity=29.6875, Blast_Score=73, Evalue=6e-15,
Organism=Escherichia coli, GI1789687, Length=105, Percent_Identity=39.0476190476191, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZNTR_HAEIN (P45277)

Other databases:

- EMBL:   L42023
- RefSeq:   NP_439766.1
- ProteinModelPortal:   P45277
- SMR:   P45277
- GeneID:   950843
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1623
- TIGR:   HI_1623
- HOGENOM:   HBG710951
- OMA:   IDEHIEH
- ProtClustDB:   CLSK892420
- BioCyc:   HINF71421:HI_1623-MONOMER
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- PRINTS:   PR00040
- SMART:   SM00422

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; SSF46955 Putativ_DNA_bind

EC number: NA

Molecular weight: Translated: 15636; Mature: 15636

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00552 HTH_MERR_1; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGALAKALGCTVETIRYYEQQGLIPPPKRTSGNFRQYNEEHLQRLSFICNCRNLDISL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCHHHHHHHHHHHCCCCCCCCH
SEIKSLLNLENASKQQAEEINRVLDKHIKEVATRIHELAHLRMKLIELREKTVSNDEDPM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
KLLLQHSGVKFVRLK
HHHHHHCCCEEEEEC
>Mature Secondary Structure
MKIGALAKALGCTVETIRYYEQQGLIPPPKRTSGNFRQYNEEHLQRLSFICNCRNLDISL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCHHHHHHHHHHHCCCCCCCCH
SEIKSLLNLENASKQQAEEINRVLDKHIKEVATRIHELAHLRMKLIELREKTVSNDEDPM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
KLLLQHSGVKFVRLK
HHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800