Click here to switch to the map view.

The map label for this gene is aroA [H]

Identifier: 16273483

GI number: 16273483

Start: 1657075

End: 1658373

Strand: Direct

Name: aroA [H]

Synonym: HI1589

Alternate gene names: 16273483

Gene position: 1657075-1658373 (Clockwise)

Preceding gene: 16273482

Following gene: 16273493

Centisome position: 90.54

GC content: 39.57

Gene sequence:

>1299_bases
ATGGAAAAAATTACTCTTGCACCAATAAGTGCGGTTGAAGGAACAATTAATTTACCAGGTTCTAAAAGTTTATCGAATCG
CGCATTACTTTTAGCCGCCTTAGCTAAAGGCACAACAAAAGTAACCAATTTATTAGATAGCGATGATATTCGACATATGC
TTAACGCACTGAAAGCATTAGGCGTACGCTATCAACTGTCTGATGATAAAACTATTTGTGAAGTAGAAGGATTAGGTGGA
ACATTCAATATACAGGACAATCTTTCACTCTTTCTTGGCAATGCTGGGACTGCAATGCGTCCATTAACCGCAGCACTTTG
CTTAAAAGGAAAAACCGAAAGCGAAATCATCTTAACGGGTGAACCTCGTATGAAAGAACGACCTATTCTTCATTTGGTCG
ATGCGCTACGCCAAGCGGGTGCAGATATTCGCTACTTAGAGAATGAGGGTTATCCTCCGCTCGCAATTCGCAACAAAGGG
ATAAAAGGTGGAAAAGTCAAAATTGATGGTTCAATTTCATCTCAATTTTTGACCGCACTTTTAATGTCTGCACCACTTGC
AGAAAATGACACAGAAATAGAAATTATCGGTGAACTAGTCTCTAAACCCTATATTGACATTACCCTTGCAATGATGCGAG
ATTTTGGTGTTCAGGTTGAAAATCATCACTACCAAAAATTTCAAGTTAAGGGAAATCAATCCTATATTTCGCCTAATAAA
TACTTGGTAGAAGGCGATGCCTCATCGGCATCTTACTTTCTCGCAGCTGGCGCCATTAAAGGAAAAGTGAAAGTAACAGG
CATTGGCAAAAACTCAATTCAGGGCGATCGTTTATTTGCTGATGTATTAGAGAAAATGGGGGCAAAAATCACTTGGGGAG
AGGATTTTATCCAAGCCGAACACGCTGAATTAAATGGTATTGATATGGATATGAACCACATTCCAGATGCCGCAATGACG
ATTGCAACCACTGCTCTTTTTGCCAACAGCGAAACCGTCATTCGCAATATTTATAACTGGCGTGTGAAAGAAACAGATCG
TTTAACGGCTATGGCAACCGAACTCCGTAAAGTCGGTGCAGAAGTCGAAGGAGGTGAAGATTTTATTCGTATTCAACCGC
TTCCACTCAATCAATTTAAACACGCCAATATTGAGACCTATAACGATCACCGTATGGCAATGTGTTTTTCTCTAATCGCA
CTATCAAACACACCAGTGACGATTTTAGATCCCAAATGTACTGCCAAAACCTTTCCTACATTCTTCAATGAATTTGAAAA
GATTTGCTTAAAAAATTAA

Upstream 100 bases:

>100_bases
GTGCTGGCCGTGATGTGGAAAAAACCGTGTTAAGTCGCGCCCTTGATCTCGCTTTACACGATAGAATTTTTGTTTATAAA
AATAAAACGGTGGTGTTGTA

Downstream 100 bases:

>100_bases
GTAAAAAAGTGCGGTCAATTTCAAAACAGTTTTCAAATTAACCGCACTTTCATTCCATTCTAAAAAAATCCTAAATAAAG
ATTATTTATACCGTTTTTTC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MEKITLAPISAVEGTINLPGSKSLSNRALLLAALAKGTTKVTNLLDSDDIRHMLNALKALGVRYQLSDDKTICEVEGLGG
TFNIQDNLSLFLGNAGTAMRPLTAALCLKGKTESEIILTGEPRMKERPILHLVDALRQAGADIRYLENEGYPPLAIRNKG
IKGGKVKIDGSISSQFLTALLMSAPLAENDTEIEIIGELVSKPYIDITLAMMRDFGVQVENHHYQKFQVKGNQSYISPNK
YLVEGDASSASYFLAAGAIKGKVKVTGIGKNSIQGDRLFADVLEKMGAKITWGEDFIQAEHAELNGIDMDMNHIPDAAMT
IATTALFANSETVIRNIYNWRVKETDRLTAMATELRKVGAEVEGGEDFIRIQPLPLNQFKHANIETYNDHRMAMCFSLIA
LSNTPVTILDPKCTAKTFPTFFNEFEKICLKN

Sequences:

>Translated_432_residues
MEKITLAPISAVEGTINLPGSKSLSNRALLLAALAKGTTKVTNLLDSDDIRHMLNALKALGVRYQLSDDKTICEVEGLGG
TFNIQDNLSLFLGNAGTAMRPLTAALCLKGKTESEIILTGEPRMKERPILHLVDALRQAGADIRYLENEGYPPLAIRNKG
IKGGKVKIDGSISSQFLTALLMSAPLAENDTEIEIIGELVSKPYIDITLAMMRDFGVQVENHHYQKFQVKGNQSYISPNK
YLVEGDASSASYFLAAGAIKGKVKVTGIGKNSIQGDRLFADVLEKMGAKITWGEDFIQAEHAELNGIDMDMNHIPDAAMT
IATTALFANSETVIRNIYNWRVKETDRLTAMATELRKVGAEVEGGEDFIRIQPLPLNQFKHANIETYNDHRMAMCFSLIA
LSNTPVTILDPKCTAKTFPTFFNEFEKICLKN
>Mature_432_residues
MEKITLAPISAVEGTINLPGSKSLSNRALLLAALAKGTTKVTNLLDSDDIRHMLNALKALGVRYQLSDDKTICEVEGLGG
TFNIQDNLSLFLGNAGTAMRPLTAALCLKGKTESEIILTGEPRMKERPILHLVDALRQAGADIRYLENEGYPPLAIRNKG
IKGGKVKIDGSISSQFLTALLMSAPLAENDTEIEIIGELVSKPYIDITLAMMRDFGVQVENHHYQKFQVKGNQSYISPNK
YLVEGDASSASYFLAAGAIKGKVKVTGIGKNSIQGDRLFADVLEKMGAKITWGEDFIQAEHAELNGIDMDMNHIPDAAMT
IATTALFANSETVIRNIYNWRVKETDRLTAMATELRKVGAEVEGGEDFIRIQPLPLNQFKHANIETYNDHRMAMCFSLIA
LSNTPVTILDPKCTAKTFPTFFNEFEKICLKN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=429, Percent_Identity=71.3286713286713, Blast_Score=598, Evalue=1e-172,
Organism=Saccharomyces cerevisiae, GI6320332, Length=444, Percent_Identity=40.0900900900901, Blast_Score=272, Evalue=7e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 47413; Mature: 47413

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKITLAPISAVEGTINLPGSKSLSNRALLLAALAKGTTKVTNLLDSDDIRHMLNALKAL
CCCEEECCHHHCCCEEECCCCCCCCCHHHEEHHHHCCHHHHHHHCCCHHHHHHHHHHHHH
GVRYQLSDDKTICEVEGLGGTFNIQDNLSLFLGNAGTAMRPLTAALCLKGKTESEIILTG
CEEEEECCCCEEEEEECCCCEEEECCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEC
EPRMKERPILHLVDALRQAGADIRYLENEGYPPLAIRNKGIKGGKVKIDGSISSQFLTAL
CCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCCEEEECCCHHHHHHHHH
LMSAPLAENDTEIEIIGELVSKPYIDITLAMMRDFGVQVENHHYQKFQVKGNQSYISPNK
HHHCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHCCEECCCCEEEEEEECCCCEECCCC
YLVEGDASSASYFLAAGAIKGKVKVTGIGKNSIQGDRLFADVLEKMGAKITWGEDFIQAE
EEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEEECHHHHHHH
HAELNGIDMDMNHIPDAAMTIATTALFANSETVIRNIYNWRVKETDRLTAMATELRKVGA
CCCCCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCEECCCHHHHHHHHHHHHHCC
EVEGGEDFIRIQPLPLNQFKHANIETYNDHRMAMCFSLIALSNTPVTILDPKCTAKTFPT
CCCCCCCEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHH
FFNEFEKICLKN
HHHHHHHHHCCC
>Mature Secondary Structure
MEKITLAPISAVEGTINLPGSKSLSNRALLLAALAKGTTKVTNLLDSDDIRHMLNALKAL
CCCEEECCHHHCCCEEECCCCCCCCCHHHEEHHHHCCHHHHHHHCCCHHHHHHHHHHHHH
GVRYQLSDDKTICEVEGLGGTFNIQDNLSLFLGNAGTAMRPLTAALCLKGKTESEIILTG
CEEEEECCCCEEEEEECCCCEEEECCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEC
EPRMKERPILHLVDALRQAGADIRYLENEGYPPLAIRNKGIKGGKVKIDGSISSQFLTAL
CCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCCEEEECCCHHHHHHHHH
LMSAPLAENDTEIEIIGELVSKPYIDITLAMMRDFGVQVENHHYQKFQVKGNQSYISPNK
HHHCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHCCEECCCCEEEEEEECCCCEECCCC
YLVEGDASSASYFLAAGAIKGKVKVTGIGKNSIQGDRLFADVLEKMGAKITWGEDFIQAE
EEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEEECHHHHHHH
HAELNGIDMDMNHIPDAAMTIATTALFANSETVIRNIYNWRVKETDRLTAMATELRKVGA
CCCCCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCEECCCHHHHHHHHHHHHHCC
EVEGGEDFIRIQPLPLNQFKHANIETYNDHRMAMCFSLIALSNTPVTILDPKCTAKTFPT
CCCCCCCEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHH
FFNEFEKICLKN
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA