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The map label for this gene is gam

Identifier: 16273387

GI number: 16273387

Start: 1565297

End: 1565806

Strand: Direct

Name: gam

Synonym: HI1483

Alternate gene names: NA

Gene position: 1565297-1565806 (Clockwise)

Preceding gene: 16273386

Following gene: 16273388

Centisome position: 85.53

GC content: 47.65

Gene sequence:

>510_bases
ATGGCAACGAAAGTAAAAAGCCAAGCGAAATTACGCTTTGTAAGCGTAGAACAGGTGCAAAGTGCGATTAAAGAAATTGG
CGATTTAAGCCGTGAACATACCCGCCTTGCGACCGAGATGAACGACAAGATTGGGGCAACAAGTGAACACTATGCTCCGA
AATTGAAAGCCTTAAAAGAAGAGATTGAGCCATTGCAAAAGGCGGTGCAGGAATACTGCGAGGCAAACCGTGATGAGCTG
ACCGAGTTCGGCAAAACCAAAACGGCGAATTTTGTGACAGGTGAAGTGCAATGGCGACAACGCCCACCTTCAGTCGCTAT
TCGTGGGGCGGAAGCTGTGATGGAATTCTTGCAACGTATGGGCTTCGACCGCTTTATTCGCACCAGGCAAGAAATCAACA
AGGAAGCGTTGCTCAATGAGCCAGAAGTGGCAAAAGGGATTGCCGGCGTGACAATTAAACAAGGGCTAGAAGATTTTGTG
ATCAAACCATTTGAGCAGGATGCGAGATGA

Upstream 100 bases:

>100_bases
TGAAAAACGGCATCCGTATTTACCTAAATCAAATGATGGTAAAAGGCGTAAAATTTATTTGGAAATCAGATGTAACTAAA
CATTAACCACAGGAGAAACT

Downstream 100 bases:

>100_bases
TGGACGATTTACAAGATGTAAGCAGATTAAGAGAAGCATATCAGTTTTATCAAAAAGCAAAACAAGATGAAGATTCGATT
GTTTGCGGTTGTTTAAATGA

Product: host-nuclease inhibitor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MATKVKSQAKLRFVSVEQVQSAIKEIGDLSREHTRLATEMNDKIGATSEHYAPKLKALKEEIEPLQKAVQEYCEANRDEL
TEFGKTKTANFVTGEVQWRQRPPSVAIRGAEAVMEFLQRMGFDRFIRTRQEINKEALLNEPEVAKGIAGVTIKQGLEDFV
IKPFEQDAR

Sequences:

>Translated_169_residues
MATKVKSQAKLRFVSVEQVQSAIKEIGDLSREHTRLATEMNDKIGATSEHYAPKLKALKEEIEPLQKAVQEYCEANRDEL
TEFGKTKTANFVTGEVQWRQRPPSVAIRGAEAVMEFLQRMGFDRFIRTRQEINKEALLNEPEVAKGIAGVTIKQGLEDFV
IKPFEQDAR
>Mature_168_residues
ATKVKSQAKLRFVSVEQVQSAIKEIGDLSREHTRLATEMNDKIGATSEHYAPKLKALKEEIEPLQKAVQEYCEANRDELT
EFGKTKTANFVTGEVQWRQRPPSVAIRGAEAVMEFLQRMGFDRFIRTRQEINKEALLNEPEVAKGIAGVTIKQGLEDFVI
KPFEQDAR

Specific function: Protects linear double stranded DNA of Mu genome from exonuclease degradation

COG id: COG4396

COG function: function code R; Mu-like prophage host-nuclease inhibitor protein Gam

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To phage Mu protein gam

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VGAM_HAEIN (O05070)

Other databases:

- EMBL:   L42023
- PIR:   D64126
- RefSeq:   NP_439634.1
- ProteinModelPortal:   O05070
- SMR:   O05070
- GeneID:   950566
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1483
- NMPDR:   fig|71421.1.peg.1414
- TIGR:   HI_1483
- HOGENOM:   HBG660827
- OMA:   AVQAYCE
- ProtClustDB:   CLSK879454
- BioCyc:   HINF71421:HI_1483-MONOMER
- InterPro:   IPR009951

Pfam domain/function: PF07352 Phage_Mu_Gam

EC number: NA

Molecular weight: Translated: 19193; Mature: 19062

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKVKSQAKLRFVSVEQVQSAIKEIGDLSREHTRLATEMNDKIGATSEHYAPKLKALKE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EIEPLQKAVQEYCEANRDELTEFGKTKTANFVTGEVQWRQRPPSVAIRGAEAVMEFLQRM
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEECCHHHCCCCCCCEECCHHHHHHHHHHH
GFDRFIRTRQEINKEALLNEPEVAKGIAGVTIKQGLEDFVIKPFEQDAR
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHCCCHHCCCC
>Mature Secondary Structure 
ATKVKSQAKLRFVSVEQVQSAIKEIGDLSREHTRLATEMNDKIGATSEHYAPKLKALKE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EIEPLQKAVQEYCEANRDELTEFGKTKTANFVTGEVQWRQRPPSVAIRGAEAVMEFLQRM
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEECCHHHCCCCCCCEECCHHHHHHHHHHH
GFDRFIRTRQEINKEALLNEPEVAKGIAGVTIKQGLEDFVIKPFEQDAR
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800