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The map label for this gene is muA

Identifier: 16273382

GI number: 16273382

Start: 1561212

End: 1563275

Strand: Direct

Name: muA

Synonym: HI1478

Alternate gene names: NA

Gene position: 1561212-1563275 (Clockwise)

Preceding gene: 16273381

Following gene: 16273383

Centisome position: 85.31

GC content: 48.18

Gene sequence:

>2064_bases
ATGGATAATCAAAGCTTAAAAACGCACTATTCAGTGTATGAATTAGCAAACTTAAAGCTAAAAACACTACCTTCAGCCCC
CAAAAACATTTGGGAACAAGCCAAGCGAGAAAACTGGAAATCTCAAAAACGCCAAGGGCGTGGTGGCGGGCTGGAATATG
AATTAGCCAGTTTGCCAATCGAAGTGCAAAACGAGCTTCTGCTCAAAACTACCCCAGAGCAAACGGCGGTAGCTTTGCAA
AAAATAGAAGAAACTCGACCGCTTGCAAGCAATGAAGTCTGGCAATTATGGGACGAAGCAAGTGCAAAAGCCCAAGAGCA
AGCAAAAATCAAACTTGGCACGATGTTTGCAGTAGCAAATTTAGTGGAAAGCGGTGTGAACGTGTTAGATGCCTTCCGGC
TTGTCTGTGGCAAAGAAAATGCCGAACGGCTGAAAAATAACGAAAAATTACTCTCAGTTGGTTCTTTAAAAAATTGGTGG
TATCGGGTCAAAGACGCCCCACGGCAAGATTGGCTGCCCTTGATGCTCAACAACAGCGGCAAGAGTAGCAAAAACGTGGC
AGAAATAGATGAAGCTGCTTGGCAGTTCTTCAAAAATTTCTACTACAGTCGTGAAAAACCCTCACTGGCTCACAGCTATG
AGGTATTAAAACAAGCCGCACAATACAACGGTTGGCGCATTCCCTCTCGCTCTTCGCTAAAACGCAAAATGGAACGAGAT
GTACCAAAAACCGAAGAAGTGTTCCGTCGTGAAGGCCAATACGCATTAAGTCGGCTTTATCCCTCACAGGTTCGCACCGT
GGCAATGTTACAAGCGATGGAGTGGATCAACGGCGACGGTTATCAACACAACGTTTGGGTGCGATTCCCTGATGGCGAAA
TTAAACGCCCGAAAACATGGCTTTGGCAAGATGTTCGCACCCGAAAAGTGCTGGCCGCTAGAACCGATAAATCGGAAAAC
ACCGACACCATACGCCTCAGTCTGCTTGATGTGATTAGTCGCTACGGTTTGCCGAAACACTTAACCATCGACAACACCCG
AGCGGCAGCCAACAAGAAAATGACGGGCGGGGTAAAAAACCGCTACCGCTATCAAGTAAACGAAAACGAAGTGCAAGGCA
TTATTCCGGCACTCGGTATCGAACTGCACTGGACGTCGATTCAATTCGGCAAGGGGCGCGGGCAAGCCAAACCAATTGAG
CGTGCCTTCTCTCACGGCGGTTTGGGAGATTATGTCGATAAGCACCTGTTATTACGCGGGGCTTATGCAGGGGCGAATGC
CTACGAAAAGCCCGACTATGACGGCAAAAACGGCGCAGAACAGCCTGTCGATTACGCCACATTCTTAATGGCATTAGAGC
AAGGCATTCAGCAATGGAACAACGTGGGCAACCGCCTCACCGAAATTTGTGCAGGCAAAAGCAGTTATGCCGAAGCCTTT
GAGCGAGATTGGGCTGTTGCCGAAAAACGCCCGATTAGCCAAAGCCAAATGCGGTTGTTGCTTACCCTGCATGAGGAAGT
TCGCCTTAACCAAGACGGTACCTTCTACCTAAACGCAGGCAAAATCGGTACGAACAAAAACCGCTATGAGTCACTGGCGC
TTATCGGTACCTCACACAAACGCGTTGTGGTGCGCTACGACCCAGCCAATCTGCACGACAAAGTGTGGGTTTATGCCTTW
ACGGGCGAATACTTGGCGGAAGCGGAAATCACCGAAAAAGCAGGCTTTGGCGACCAAATGGCAGGACGCGAACACAACAA
AGCAATGCGCAACTGGGTAAAACATACCGAAAAAGCGGCGAAAGAACGCGCTAAAGCGGAAGAAATGGAACTCAGCAATT
ACGCCCCGGCGGTCGAATTTGAAGAGCGGTTCTTGGAAATGTTGCCAGAGCCGGTAAAAGCCCCTCAAACGCAAGCAGAA
GAGGTGGAATATGAAGAAGTGCTAGATTTCAACACCGTGCGAAAAGTACCGAAAGCAGTGGAAGTAGAAGCCGAAGAAAT
CAGCGAATTTAATCGTGATTGGGAAAAGGGTTTAGAGCTTTTAAAGAAAAGTAAAGGGCGTTAA

Upstream 100 bases:

>100_bases
TGAAGTTATCTGGGCTGGTCGTTTTGCTGAACGAAATAAAAGACCAACATTACAACATAAGTACTGATTTTAACCGTAAA
AGTTATAAAAAGGAACATTT

Downstream 100 bases:

>100_bases
ACCAACCGCCTTTAAACCAGATTTAAACAGGGTTTAAACGCCCTAAGGAGAACAAGATGAGCAATATCACATTAAACGAA
AACGCAATGCTTTATTTAAA

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MDNQSLKTHYSVYELANLKLKTLPSAPKNIWEQAKRENWKSQKRQGRGGGLEYELASLPIEVQNELLLKTTPEQTAVALQ
KIEETRPLASNEVWQLWDEASAKAQEQAKIKLGTMFAVANLVESGVNVLDAFRLVCGKENAERLKNNEKLLSVGSLKNWW
YRVKDAPRQDWLPLMLNNSGKSSKNVAEIDEAAWQFFKNFYYSREKPSLAHSYEVLKQAAQYNGWRIPSRSSLKRKMERD
VPKTEEVFRREGQYALSRLYPSQVRTVAMLQAMEWINGDGYQHNVWVRFPDGEIKRPKTWLWQDVRTRKVLAARTDKSEN
TDTIRLSLLDVISRYGLPKHLTIDNTRAAANKKMTGGVKNRYRYQVNENEVQGIIPALGIELHWTSIQFGKGRGQAKPIE
RAFSHGGLGDYVDKHLLLRGAYAGANAYEKPDYDGKNGAEQPVDYATFLMALEQGIQQWNNVGNRLTEICAGKSSYAEAF
ERDWAVAEKRPISQSQMRLLLTLHEEVRLNQDGTFYLNAGKIGTNKNRYESLALIGTSHKRVVVRYDPANLHDKVWVYAX
TGEYLAEAEITEKAGFGDQMAGREHNKAMRNWVKHTEKAAKERAKAEEMELSNYAPAVEFEERFLEMLPEPVKAPQTQAE
EVEYEEVLDFNTVRKVPKAVEVEAEEISEFNRDWEKGLELLKKSKGR

Sequences:

>Translated_687_residues
MDNQSLKTHYSVYELANLKLKTLPSAPKNIWEQAKRENWKSQKRQGRGGGLEYELASLPIEVQNELLLKTTPEQTAVALQ
KIEETRPLASNEVWQLWDEASAKAQEQAKIKLGTMFAVANLVESGVNVLDAFRLVCGKENAERLKNNEKLLSVGSLKNWW
YRVKDAPRQDWLPLMLNNSGKSSKNVAEIDEAAWQFFKNFYYSREKPSLAHSYEVLKQAAQYNGWRIPSRSSLKRKMERD
VPKTEEVFRREGQYALSRLYPSQVRTVAMLQAMEWINGDGYQHNVWVRFPDGEIKRPKTWLWQDVRTRKVLAARTDKSEN
TDTIRLSLLDVISRYGLPKHLTIDNTRAAANKKMTGGVKNRYRYQVNENEVQGIIPALGIELHWTSIQFGKGRGQAKPIE
RAFSHGGLGDYVDKHLLLRGAYAGANAYEKPDYDGKNGAEQPVDYATFLMALEQGIQQWNNVGNRLTEICAGKSSYAEAF
ERDWAVAEKRPISQSQMRLLLTLHEEVRLNQDGTFYLNAGKIGTNKNRYESLALIGTSHKRVVVRYDPANLHDKVWVYAX
TGEYLAEAEITEKAGFGDQMAGREHNKAMRNWVKHTEKAAKERAKAEEMELSNYAPAVEFEERFLEMLPEPVKAPQTQAE
EVEYEEVLDFNTVRKVPKAVEVEAEEISEFNRDWEKGLELLKKSKGR
>Mature_687_residues
MDNQSLKTHYSVYELANLKLKTLPSAPKNIWEQAKRENWKSQKRQGRGGGLEYELASLPIEVQNELLLKTTPEQTAVALQ
KIEETRPLASNEVWQLWDEASAKAQEQAKIKLGTMFAVANLVESGVNVLDAFRLVCGKENAERLKNNEKLLSVGSLKNWW
YRVKDAPRQDWLPLMLNNSGKSSKNVAEIDEAAWQFFKNFYYSREKPSLAHSYEVLKQAAQYNGWRIPSRSSLKRKMERD
VPKTEEVFRREGQYALSRLYPSQVRTVAMLQAMEWINGDGYQHNVWVRFPDGEIKRPKTWLWQDVRTRKVLAARTDKSEN
TDTIRLSLLDVISRYGLPKHLTIDNTRAAANKKMTGGVKNRYRYQVNENEVQGIIPALGIELHWTSIQFGKGRGQAKPIE
RAFSHGGLGDYVDKHLLLRGAYAGANAYEKPDYDGKNGAEQPVDYATFLMALEQGIQQWNNVGNRLTEICAGKSSYAEAF
ERDWAVAEKRPISQSQMRLLLTLHEEVRLNQDGTFYLNAGKIGTNKNRYESLALIGTSHKRVVVRYDPANLHDKVWVYAX
TGEYLAEAEITEKAGFGDQMAGREHNKAMRNWVKHTEKAAKERAKAEEMELSNYAPAVEFEERFLEMLPEPVKAPQTQAE
EVEYEEVLDFNTVRKVPKAVEVEAEEISEFNRDWEKGLELLKKSKGR

Specific function: This transposase is essential for integration, replication-transposition, and excision of Mu-like viral DNA

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To phage Mu protein A

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRA_HAEIN (O05069)

Other databases:

- EMBL:   L42023
- PIR:   B64126
- RefSeq:   NP_439629.1
- ProteinModelPortal:   O05069
- GeneID:   950583
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1478
- NMPDR:   fig|71421.1.peg.1409
- TIGR:   HI_1478
- HOGENOM:   HBG353891
- OMA:   RYRFKVK
- ProtClustDB:   CLSK2518372
- BioCyc:   HINF71421:HI_1478-MONOMER
- InterPro:   IPR009061
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015126
- InterPro:   IPR003314
- InterPro:   IPR012337
- InterPro:   IPR015378
- InterPro:   IPR004189
- InterPro:   IPR009004
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.60
- Gene3D:   G3DSA:2.30.30.130
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF09299 Mu-transpos_C; PF02316 Mu_DNA_bind; PF09039 Mu_I-gamma; PF02914 Mu_transposase; SSF46689 Homeodomain_like; SSF46955 Putativ_DNA_bind; SSF53098 RNaseH_fold; SSF50610 Transposase-like_Mu_C

EC number: NA

Molecular weight: Translated: 78667; Mature: 78667

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQSLKTHYSVYELANLKLKTLPSAPKNIWEQAKRENWKSQKRQGRGGGLEYELASLPI
CCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCH
EVQNELLLKTTPEQTAVALQKIEETRPLASNEVWQLWDEASAKAQEQAKIKLGTMFAVAN
HHCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVESGVNVLDAFRLVCGKENAERLKNNEKLLSVGSLKNWWYRVKDAPRQDWLPLMLNNSG
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEECCCHHHHHHCCCCCCCCCCCEEEECCCC
KSSKNVAEIDEAAWQFFKNFYYSREKPSLAHSYEVLKQAAQYNGWRIPSRSSLKRKMERD
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
VPKTEEVFRREGQYALSRLYPSQVRTVAMLQAMEWINGDGYQHNVWVRFPDGEIKRPKTW
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHH
LWQDVRTRKVLAARTDKSENTDTIRLSLLDVISRYGLPKHLTIDNTRAAANKKMTGGVKN
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHCCCCCCCCCCC
RYRYQVNENEVQGIIPALGIELHWTSIQFGKGRGQAKPIERAFSHGGLGDYVDKHLLLRG
CEEEECCCHHHHHHHHHHCEEEEEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHH
AYAGANAYEKPDYDGKNGAEQPVDYATFLMALEQGIQQWNNVGNRLTEICAGKSSYAEAF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ERDWAVAEKRPISQSQMRLLLTLHEEVRLNQDGTFYLNAGKIGTNKNRYESLALIGTSHK
HHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCHHHEEEEEECCCC
RVVVRYDPANLHDKVWVYAXTGEYLAEAEITEKAGFGDQMAGREHNKAMRNWVKHTEKAA
EEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHH
KERAKAEEMELSNYAPAVEFEERFLEMLPEPVKAPQTQAEEVEYEEVLDFNTVRKVPKAV
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHCHHHHHHCCHHH
EVEAEEISEFNRDWEKGLELLKKSKGR
HCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDNQSLKTHYSVYELANLKLKTLPSAPKNIWEQAKRENWKSQKRQGRGGGLEYELASLPI
CCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCH
EVQNELLLKTTPEQTAVALQKIEETRPLASNEVWQLWDEASAKAQEQAKIKLGTMFAVAN
HHCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVESGVNVLDAFRLVCGKENAERLKNNEKLLSVGSLKNWWYRVKDAPRQDWLPLMLNNSG
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEECCCHHHHHHCCCCCCCCCCCEEEECCCC
KSSKNVAEIDEAAWQFFKNFYYSREKPSLAHSYEVLKQAAQYNGWRIPSRSSLKRKMERD
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
VPKTEEVFRREGQYALSRLYPSQVRTVAMLQAMEWINGDGYQHNVWVRFPDGEIKRPKTW
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHH
LWQDVRTRKVLAARTDKSENTDTIRLSLLDVISRYGLPKHLTIDNTRAAANKKMTGGVKN
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHCCCCCCCCCCC
RYRYQVNENEVQGIIPALGIELHWTSIQFGKGRGQAKPIERAFSHGGLGDYVDKHLLLRG
CEEEECCCHHHHHHHHHHCEEEEEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHH
AYAGANAYEKPDYDGKNGAEQPVDYATFLMALEQGIQQWNNVGNRLTEICAGKSSYAEAF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ERDWAVAEKRPISQSQMRLLLTLHEEVRLNQDGTFYLNAGKIGTNKNRYESLALIGTSHK
HHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCHHHEEEEEECCCC
RVVVRYDPANLHDKVWVYAXTGEYLAEAEITEKAGFGDQMAGREHNKAMRNWVKHTEKAA
EEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHH
KERAKAEEMELSNYAPAVEFEERFLEMLPEPVKAPQTQAEEVEYEEVLDFNTVRKVPKAV
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHCHHHHHHCCHHH
EVEAEEISEFNRDWEKGLELLKKSKGR
HCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800