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The map label for this gene is thiL [H]

Identifier: 16273217

GI number: 16273217

Start: 1384139

End: 1385176

Strand: Direct

Name: thiL [H]

Synonym: HI1305

Alternate gene names: 16273217

Gene position: 1384139-1385176 (Clockwise)

Preceding gene: 16273216

Following gene: 16273218

Centisome position: 75.63

GC content: 37.96

Gene sequence:

>1038_bases
ATGGCGCGCGTTTTTAATGCGTGCCTTTTCTTTTATAAGATAGGTGGAAAAATGGCAATGGGTGAATTTGATTTAATTAA
ACGATATTTTCAGCAACAAATATTAGTTGATGATTCCGTTCAATTATCTATTGGCGACGATTGTGCGCTGGTTTCCGTGC
CAGAGAATTATCAGCTTGCCATTACGACCGATACAATGGTGGAAAATACGCATTTTTTACCAACCATTTCACCTGAGGAC
TTGGCTTATAAGGCGGTTGCAACAAATTTAAGTGATCTTGCTGCAATGGGGGCACAGCCAAAATGGGTTTCACTGGCATT
AACTTTGCCAAATGTAGACGAAAATTGGATTTCAACATTTAGCCAAAGTTTATTACACACGTTAAAACAATACAACGTCA
CATTAATTGGTGGCGATACTACAAAAGGTAATTTGTCTATTACGATTACGGCACAAGGTTTTGTCGAAAAAAACAAAGGA
ATTTGTCGGCATAAAGCACAAATCGGTGATTTAATTTATGTTTCAAGCACTTTAGGCGATAGCGCGGCAGGTTTAACACA
AATTTTATTGGGCAAAAGTGCGGTTGATTCTGATGATGTTTTTTTGCAACAACGACATCTTAGACCCACACCTAGAATTG
AACTTGGGCAGGCGTTAATTGGCATTGCTCATGTTGCCATTGATCTTTCCGATGGGCTAATATCTGATTTAGGGCATATT
CTTGAACGAAGTCAATGTAGTGCTGAAGTTGAATTGACTGCATTACCTCTTTCATCATCGATTTTAAATAAATATGATCG
CACTCAAGCGGAACAATTTGCCTTAAGTGGTGGCGAAGACTATGAACTTTGTTTTACCATACCGCCCGAATATAAAGATG
AATTAGAATTACGCTTGAAAAAACTGAACGTGCCTTGCACTTGTATTGGTAAAATTAATGAAAAGTGCGGTGACTTTTCT
CCCCGTTTTTTACGGGATGGAAAACCTGTGAATATAACTTTTTCAAGCGGTTTCGATCATTTTAAGGAATCAAAATGA

Upstream 100 bases:

>100_bases
GCAAAAGTATTCGGTGCAGATGAAAGCCATAAATATATCAATGGCGTACTTGATAAAATCGCACCAGCATTAGGGCGTAA
ATAATCCTTTTAAACTGAGA

Downstream 100 bases:

>100_bases
CAGAAAATAATCCTCTTAAAAAAATCTCTCTTTTAAATCCTATTCATTTACTTGCCGTTGGTTTTGGCTCAGGCTTAATT
CATCCTGCTCCCGGCACTTG

Product: thiamin-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MARVFNACLFFYKIGGKMAMGEFDLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLAITTDTMVENTHFLPTISPED
LAYKAVATNLSDLAAMGAQPKWVSLALTLPNVDENWISTFSQSLLHTLKQYNVTLIGGDTTKGNLSITITAQGFVEKNKG
ICRHKAQIGDLIYVSSTLGDSAAGLTQILLGKSAVDSDDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHI
LERSQCSAEVELTALPLSSSILNKYDRTQAEQFALSGGEDYELCFTIPPEYKDELELRLKKLNVPCTCIGKINEKCGDFS
PRFLRDGKPVNITFSSGFDHFKESK

Sequences:

>Translated_345_residues
MARVFNACLFFYKIGGKMAMGEFDLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLAITTDTMVENTHFLPTISPED
LAYKAVATNLSDLAAMGAQPKWVSLALTLPNVDENWISTFSQSLLHTLKQYNVTLIGGDTTKGNLSITITAQGFVEKNKG
ICRHKAQIGDLIYVSSTLGDSAAGLTQILLGKSAVDSDDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHI
LERSQCSAEVELTALPLSSSILNKYDRTQAEQFALSGGEDYELCFTIPPEYKDELELRLKKLNVPCTCIGKINEKCGDFS
PRFLRDGKPVNITFSSGFDHFKESK
>Mature_344_residues
ARVFNACLFFYKIGGKMAMGEFDLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLAITTDTMVENTHFLPTISPEDL
AYKAVATNLSDLAAMGAQPKWVSLALTLPNVDENWISTFSQSLLHTLKQYNVTLIGGDTTKGNLSITITAQGFVEKNKGI
CRHKAQIGDLIYVSSTLGDSAAGLTQILLGKSAVDSDDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHIL
ERSQCSAEVELTALPLSSSILNKYDRTQAEQFALSGGEDYELCFTIPPEYKDELELRLKKLNVPCTCIGKINEKCGDFSP
RFLRDGKPVNITFSSGFDHFKESK

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=325, Percent_Identity=52.6153846153846, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 37964; Mature: 37833

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVFNACLFFYKIGGKMAMGEFDLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLA
CCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHEEECCCEEEEECCCEEEEECCCCCEEE
ITTDTMVENTHFLPTISPEDLAYKAVATNLSDLAAMGAQPKWVSLALTLPNVDENWISTF
EEECCEECCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHH
SQSLLHTLKQYNVTLIGGDTTKGNLSITITAQGFVEKNKGICRHKAQIGDLIYVSSTLGD
HHHHHHHHHHCCEEEEECCCCCCEEEEEEEECCCEECCCCHHHHHHHHCCEEEEECCCCC
SAAGLTQILLGKSAVDSDDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHI
CHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHH
LERSQCSAEVELTALPLSSSILNKYDRTQAEQFALSGGEDYELCFTIPPEYKDELELRLK
HHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHH
KLNVPCTCIGKINEKCGDFSPRFLRDGKPVNITFSSGFDHFKESK
HCCCCEEEEECHHHHCCCCCCHHHCCCCCEEEEECCCCCHHHCCC
>Mature Secondary Structure 
ARVFNACLFFYKIGGKMAMGEFDLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLA
CHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHEEECCCEEEEECCCEEEEECCCCCEEE
ITTDTMVENTHFLPTISPEDLAYKAVATNLSDLAAMGAQPKWVSLALTLPNVDENWISTF
EEECCEECCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHH
SQSLLHTLKQYNVTLIGGDTTKGNLSITITAQGFVEKNKGICRHKAQIGDLIYVSSTLGD
HHHHHHHHHHCCEEEEECCCCCCEEEEEEEECCCEECCCCHHHHHHHHCCEEEEECCCCC
SAAGLTQILLGKSAVDSDDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHI
CHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHH
LERSQCSAEVELTALPLSSSILNKYDRTQAEQFALSGGEDYELCFTIPPEYKDELELRLK
HHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHH
KLNVPCTCIGKINEKCGDFSPRFLRDGKPVNITFSSGFDHFKESK
HCCCCEEEEECHHHHCCCCCCHHHCCCCCEEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]