Click here to switch to the map view.

The map label for this gene is mraY [H]

Identifier: 16273061

GI number: 16273061

Start: 1202529

End: 1203611

Strand: Direct

Name: mraY [H]

Synonym: HI1135

Alternate gene names: 16273061

Gene position: 1202529-1203611 (Clockwise)

Preceding gene: 16273060

Following gene: 16273062

Centisome position: 65.71

GC content: 40.07

Gene sequence:

>1083_bases
ATGTTAGTCTGGCTTGCTGAATATCTTGTTCGTTACGAAACCGCGTTTAATGCTATTTCTTATATTACAGTCCGCGCAAA
TCTTGCATTATTAACCGCACTTTTTATCTCACTTTGGATTGGCCCTAAAGTGATCAAACGCTTGCAGATCTTAAAATTTG
GCCAAGAAGTGCGAAATGATGGCCCTGAAAGTCACTTTGCAAAAAAAGGCACACCCACTATGGGTGGTGTGATGATTTTA
TTCTCTATTGGCGTAAGTACGTTATTATGGGCAAATCTTGCTAATCCGTATATTTGGGTTTGTTTATTTGTTTTATTTGG
ATACGGCGCAATTGGTTTTGTGGATGATTTCCGTAAAATTACCCGTAAAAATACTGATGGATTGATTGCTCGTTGGAAAT
ATTTCTGGATGTCTGTGGTGGCATTAGTGGCAATCCTTTGGCTTTATTGGCTTGGTCACGACACTGATGCCACCCGTTTA
GTGATTCCATTCTTTAAAGACATTATGCCTCAATTAGGTTTGTTCTATATTGTGTTATCTTACTTTGTGATTGTTGGCAC
GGGTAATGCAGTGAATTTAACCGACGGTTTAGATGGATTAGCGATTATGCCTACTGCGCTTGTTGCAGGTGCGTTTGCTT
TAATTGCTTGGGCTACAGGTAACGTGAATTTCGCAGAATATTTGCACATTCCGTATATTAAATACAGTTCTGAAGTAGTG
GTGTTCTGTACAGCTATTGTTGGCGCGAGTTTGGGATTCTTATGGTTTAATACTTATCCAGCTCAAGTATTTATGGGGGA
CGTGGGTTCTCTAGCATTAGGTGGTGCGCTGGGTGTTGTAGCAATTCTTGTTCGTCAGGAATTTTTGCTTGTGATAATGG
GTGGTGTATTTGTTGTTGAAGCACTCTCTGTTATTTTGCAAGTAGGGTCTTATAAGTTACGCAAACAACGCATTTTTAGA
ATGGCACCGATTCACCACCATTTTGAATTGAAGGGATGGCCTGAGCCAAGAGTGATTATTCGGTTTTGGATTATTTCCTT
AATGCTGGTGTTGATGGGATTGGTCACCTTGAAGTTGCGTTAA

Upstream 100 bases:

>100_bases
AAAACCAATTACAACAAAATAAAAAAGTTGTGGTGCTAGGAAAAGGCTCACGCTCAATGAAAATGGAAGATGTGATCTAT
TCATTAAAGGATAAAATTAA

Downstream 100 bases:

>100_bases
TAAATATAGCTAGGTTCGCTCTTTCACTTTTGAAAGAGCGACCTTTTTTACGTTAGTAAAGGAAATTTATATTTCCATCA
ATGATATAATTTTAAAATTT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLVWLAEYLVRYETAFNAISYITVRANLALLTALFISLWIGPKVIKRLQILKFGQEVRNDGPESHFAKKGTPTMGGVMIL
FSIGVSTLLWANLANPYIWVCLFVLFGYGAIGFVDDFRKITRKNTDGLIARWKYFWMSVVALVAILWLYWLGHDTDATRL
VIPFFKDIMPQLGLFYIVLSYFVIVGTGNAVNLTDGLDGLAIMPTALVAGAFALIAWATGNVNFAEYLHIPYIKYSSEVV
VFCTAIVGASLGFLWFNTYPAQVFMGDVGSLALGGALGVVAILVRQEFLLVIMGGVFVVEALSVILQVGSYKLRKQRIFR
MAPIHHHFELKGWPEPRVIIRFWIISLMLVLMGLVTLKLR

Sequences:

>Translated_360_residues
MLVWLAEYLVRYETAFNAISYITVRANLALLTALFISLWIGPKVIKRLQILKFGQEVRNDGPESHFAKKGTPTMGGVMIL
FSIGVSTLLWANLANPYIWVCLFVLFGYGAIGFVDDFRKITRKNTDGLIARWKYFWMSVVALVAILWLYWLGHDTDATRL
VIPFFKDIMPQLGLFYIVLSYFVIVGTGNAVNLTDGLDGLAIMPTALVAGAFALIAWATGNVNFAEYLHIPYIKYSSEVV
VFCTAIVGASLGFLWFNTYPAQVFMGDVGSLALGGALGVVAILVRQEFLLVIMGGVFVVEALSVILQVGSYKLRKQRIFR
MAPIHHHFELKGWPEPRVIIRFWIISLMLVLMGLVTLKLR
>Mature_360_residues
MLVWLAEYLVRYETAFNAISYITVRANLALLTALFISLWIGPKVIKRLQILKFGQEVRNDGPESHFAKKGTPTMGGVMIL
FSIGVSTLLWANLANPYIWVCLFVLFGYGAIGFVDDFRKITRKNTDGLIARWKYFWMSVVALVAILWLYWLGHDTDATRL
VIPFFKDIMPQLGLFYIVLSYFVIVGTGNAVNLTDGLDGLAIMPTALVAGAFALIAWATGNVNFAEYLHIPYIKYSSEVV
VFCTAIVGASLGFLWFNTYPAQVFMGDVGSLALGGALGVVAILVRQEFLLVIMGGVFVVEALSVILQVGSYKLRKQRIFR
MAPIHHHFELKGWPEPRVIIRFWIISLMLVLMGLVTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=76.6666666666667, Blast_Score=562, Evalue=1e-161,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 40316; Mature: 40316

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVWLAEYLVRYETAFNAISYITVRANLALLTALFISLWIGPKVIKRLQILKFGQEVRND
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GPESHFAKKGTPTMGGVMILFSIGVSTLLWANLANPYIWVCLFVLFGYGAIGFVDDFRKI
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHH
TRKNTDGLIARWKYFWMSVVALVAILWLYWLGHDTDATRLVIPFFKDIMPQLGLFYIVLS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
YFVIVGTGNAVNLTDGLDGLAIMPTALVAGAFALIAWATGNVNFAEYLHIPYIKYSSEVV
HHHHEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHEECCEEEECCHHH
VFCTAIVGASLGFLWFNTYPAQVFMGDVGSLALGGALGVVAILVRQEFLLVIMGGVFVVE
HHHHHHHHHHHHHHHEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSVILQVGSYKLRKQRIFRMAPIHHHFELKGWPEPRVIIRFWIISLMLVLMGLVTLKLR
HHHHHHHHCCHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVWLAEYLVRYETAFNAISYITVRANLALLTALFISLWIGPKVIKRLQILKFGQEVRND
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GPESHFAKKGTPTMGGVMILFSIGVSTLLWANLANPYIWVCLFVLFGYGAIGFVDDFRKI
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHH
TRKNTDGLIARWKYFWMSVVALVAILWLYWLGHDTDATRLVIPFFKDIMPQLGLFYIVLS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
YFVIVGTGNAVNLTDGLDGLAIMPTALVAGAFALIAWATGNVNFAEYLHIPYIKYSSEVV
HHHHEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHEECCEEEECCHHH
VFCTAIVGASLGFLWFNTYPAQVFMGDVGSLALGGALGVVAILVRQEFLLVIMGGVFVVE
HHHHHHHHHHHHHHHEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSVILQVGSYKLRKQRIFRMAPIHHHFELKGWPEPRVIIRFWIISLMLVLMGLVTLKLR
HHHHHHHHCCHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA