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The map label for this gene is lyx

Identifier: 16272961

GI number: 16272961

Start: 1091678

End: 1093135

Strand: Reverse

Name: lyx

Synonym: HI1027

Alternate gene names: 16272961

Gene position: 1093135-1091678 (Counterclockwise)

Preceding gene: 16272962

Following gene: 16272960

Centisome position: 59.73

GC content: 34.22

Gene sequence:

>1458_bases
ATGCATTACTATCTTGGTATTGATTGTGGTGGTACGTTTATAAAAGCAGCGATTTTTGATCAAAATGGTACACTACAAAG
TATTGCACGCAGAAATATTCCTATTATTAGTGAAAAACCCGGTTATGCTGAACGGGATATGGATGAATTATGGAATCTTT
GCGCGCAAGTTATTCAGAAAACTATAAGACAAAGTAGTATTTTGCCTCAACAAATAAAAGCTATTGGCATTTCTGCACAA
GGTAAAGGTGCGTTTTTTTTAGATAAAGATAATAAACCATTAGGGCGAGCAATCTTATCATCTGACCAACGGGCATACGA
AATTGTGCAATGTTGGCAAAAAGAAAACATACTACAAAAATTTTATCCTATCACACTCCAAACTCTTTGGATGGGACATC
CTGTCTCGATTTTACGCTGGATAAAAGAAAATGAACCCAGTCGATATGAGCAAATTCATACGATTTTAATGTCTCACGAT
TACCTTCGATTTTGTTTAACTGAAAAATTATATTGTGAAGAAACAAATATTTCTGAGTCTAATTTTTACAATATGCGAGA
AGGAAAATATGACATTCAGTTAGCTAAGTTATTCGGTATAACAGAATGCATAGATAAATTACCTCCAATCATTAAATCAA
ATAAAATTGCAGGATATGTAACCTCCAGAGCAGCAGAGCAATCTGGTTTGGTAGAAGGAATACCTGTTGTTGGAGGATTA
TTTGATGTGGTATCCACTGCATTATGCGCTGATTTGAAGGATGATCAACATCTTAATGTTGTATTAGGGACGTGGTCTGT
TGTTAGTGGGGTGACCCATTATATTGATGATAACCAAACAATTCCTTTTGTGTATGGCAAATATCCAGAAAAAAATAAAT
TCATTATTCATGAAGCAAGTCCAACATCAGCAGGTAATTTAGAGTGGTTTGTAAATCAATTTAATTTGCCTAACTATGAT
GACATTAATCACGAAATTGCAAAACTTAAACCCGCAAGTAGCTCAGTCTTATTTGCACCTTTTTTATATGGCTCTAATGC
TAAGTTAGGTATGCAAGCAGGGTTTTATGGAATTCAATCTCATCATACCCAAATACATTTACTCCAAGCAATTTATGAAG
GTGTGATATTTAGCCTAATGTCTCATTTAGAAAGAATGCAAGTACGTTTTCCTAATGCAAGCACCGTTCGCGTAACTGGT
GGACCAGCAAAATCAGAAGTTTGGATGCAAATGCTTGCGGATATAAGTGGTATGAGACTAGAAATCCCTAATATTGAAGA
AACTGGTTGCTTAGGTGCAGCATTGATGGCGATGCAAGCCGAAAGTGCGGTTGAAATTTCTCAAATATTAAATATTGATA
GGAAAATATTTTTACCTGATAAAAATCAATATAGTAAGTATCAGCATAAATATCATCGCTATTTAAAGTTTATTGAAGCA
TTAAAAAATTTAGACTAA

Upstream 100 bases:

>100_bases
GGCGATGATTTATTGAAGAAAGTAGATGCATTATCGGAATAGTCAATAGGCTGGATTTTACATAATAAAAATCCAGCCCA
TAAAAAACTAAGGAGAATAT

Downstream 100 bases:

>100_bases
AAAAGGAAAAGTTATGAAAAAACATAAAATCGGTATTTATGAGAAAGCATTACCGAAAAATATTACTTGGCAAGAGCGTT
TATCTCTCGCTAAAGCATGT

Product: L-xylulose kinase

Products: NA

Alternate protein names: L-xylulokinase

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MHYYLGIDCGGTFIKAAIFDQNGTLQSIARRNIPIISEKPGYAERDMDELWNLCAQVIQKTIRQSSILPQQIKAIGISAQ
GKGAFFLDKDNKPLGRAILSSDQRAYEIVQCWQKENILQKFYPITLQTLWMGHPVSILRWIKENEPSRYEQIHTILMSHD
YLRFCLTEKLYCEETNISESNFYNMREGKYDIQLAKLFGITECIDKLPPIIKSNKIAGYVTSRAAEQSGLVEGIPVVGGL
FDVVSTALCADLKDDQHLNVVLGTWSVVSGVTHYIDDNQTIPFVYGKYPEKNKFIIHEASPTSAGNLEWFVNQFNLPNYD
DINHEIAKLKPASSSVLFAPFLYGSNAKLGMQAGFYGIQSHHTQIHLLQAIYEGVIFSLMSHLERMQVRFPNASTVRVTG
GPAKSEVWMQMLADISGMRLEIPNIEETGCLGAALMAMQAESAVEISQILNIDRKIFLPDKNQYSKYQHKYHRYLKFIEA
LKNLD

Sequences:

>Translated_485_residues
MHYYLGIDCGGTFIKAAIFDQNGTLQSIARRNIPIISEKPGYAERDMDELWNLCAQVIQKTIRQSSILPQQIKAIGISAQ
GKGAFFLDKDNKPLGRAILSSDQRAYEIVQCWQKENILQKFYPITLQTLWMGHPVSILRWIKENEPSRYEQIHTILMSHD
YLRFCLTEKLYCEETNISESNFYNMREGKYDIQLAKLFGITECIDKLPPIIKSNKIAGYVTSRAAEQSGLVEGIPVVGGL
FDVVSTALCADLKDDQHLNVVLGTWSVVSGVTHYIDDNQTIPFVYGKYPEKNKFIIHEASPTSAGNLEWFVNQFNLPNYD
DINHEIAKLKPASSSVLFAPFLYGSNAKLGMQAGFYGIQSHHTQIHLLQAIYEGVIFSLMSHLERMQVRFPNASTVRVTG
GPAKSEVWMQMLADISGMRLEIPNIEETGCLGAALMAMQAESAVEISQILNIDRKIFLPDKNQYSKYQHKYHRYLKFIEA
LKNLD
>Mature_485_residues
MHYYLGIDCGGTFIKAAIFDQNGTLQSIARRNIPIISEKPGYAERDMDELWNLCAQVIQKTIRQSSILPQQIKAIGISAQ
GKGAFFLDKDNKPLGRAILSSDQRAYEIVQCWQKENILQKFYPITLQTLWMGHPVSILRWIKENEPSRYEQIHTILMSHD
YLRFCLTEKLYCEETNISESNFYNMREGKYDIQLAKLFGITECIDKLPPIIKSNKIAGYVTSRAAEQSGLVEGIPVVGGL
FDVVSTALCADLKDDQHLNVVLGTWSVVSGVTHYIDDNQTIPFVYGKYPEKNKFIIHEASPTSAGNLEWFVNQFNLPNYD
DINHEIAKLKPASSSVLFAPFLYGSNAKLGMQAGFYGIQSHHTQIHLLQAIYEGVIFSLMSHLERMQVRFPNASTVRVTG
GPAKSEVWMQMLADISGMRLEIPNIEETGCLGAALMAMQAESAVEISQILNIDRKIFLPDKNQYSKYQHKYHRYLKFIEA
LKNLD

Specific function: L-lyxose utilization. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family

Homologues:

Organism=Escherichia coli, GI1790005, Length=486, Percent_Identity=53.7037037037037, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI1789987, Length=503, Percent_Identity=25.2485089463221, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1787789, Length=515, Percent_Identity=21.9417475728155, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1789168, Length=449, Percent_Identity=21.380846325167, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LYXK_HAEIN (P44991)

Other databases:

- EMBL:   L42023
- PIR:   H64164
- RefSeq:   NP_439187.1
- ProteinModelPortal:   P44991
- SMR:   P44991
- GeneID:   949892
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1027
- NMPDR:   fig|71421.1.peg.989
- TIGR:   HI_1027
- HOGENOM:   HBG299886
- OMA:   SEYHISA
- ProtClustDB:   CLSK870414
- BioCyc:   HINF71421:HI_1027-MONOMER
- BRENDA:   2.7.1.53
- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- PANTHER:   PTHR10196

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N

EC number: =2.7.1.53

Molecular weight: Translated: 54966; Mature: 54966

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00933 FGGY_KINASES_1; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYYLGIDCGGTFIKAAIFDQNGTLQSIARRNIPIISEKPGYAERDMDELWNLCAQVIQK
CEEEEEEECCCCEEEEEEECCCCCHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHH
TIRQSSILPQQIKAIGISAQGKGAFFLDKDNKPLGRAILSSDQRAYEIVQCWQKENILQK
HHHHHCCCHHHHHHEECCCCCCCEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
FYPITLQTLWMGHPVSILRWIKENEPSRYEQIHTILMSHDYLRFCLTEKLYCEETNISES
HCCHHHEEHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
NFYNMREGKYDIQLAKLFGITECIDKLPPIIKSNKIAGYVTSRAAEQSGLVEGIPVVGGL
CCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHH
FDVVSTALCADLKDDQHLNVVLGTWSVVSGVTHYIDDNQTIPFVYGKYPEKNKFIIHEAS
HHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHCCCCCEECEEECCCCCCCCEEEEECC
PTSAGNLEWFVNQFNLPNYDDINHEIAKLKPASSSVLFAPFLYGSNAKLGMQAGFYGIQS
CCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCHHCCCCCHHC
HHTQIHLLQAIYEGVIFSLMSHLERMQVRFPNASTVRVTGGPAKSEVWMQMLADISGMRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCHHHHHHHHHHCCCCCEE
EIPNIEETGCLGAALMAMQAESAVEISQILNIDRKIFLPDKNQYSKYQHKYHRYLKFIEA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
LKNLD
HHCCC
>Mature Secondary Structure
MHYYLGIDCGGTFIKAAIFDQNGTLQSIARRNIPIISEKPGYAERDMDELWNLCAQVIQK
CEEEEEEECCCCEEEEEEECCCCCHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHH
TIRQSSILPQQIKAIGISAQGKGAFFLDKDNKPLGRAILSSDQRAYEIVQCWQKENILQK
HHHHHCCCHHHHHHEECCCCCCCEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
FYPITLQTLWMGHPVSILRWIKENEPSRYEQIHTILMSHDYLRFCLTEKLYCEETNISES
HCCHHHEEHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
NFYNMREGKYDIQLAKLFGITECIDKLPPIIKSNKIAGYVTSRAAEQSGLVEGIPVVGGL
CCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHH
FDVVSTALCADLKDDQHLNVVLGTWSVVSGVTHYIDDNQTIPFVYGKYPEKNKFIIHEAS
HHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHCCCCCEECEEECCCCCCCCEEEEECC
PTSAGNLEWFVNQFNLPNYDDINHEIAKLKPASSSVLFAPFLYGSNAKLGMQAGFYGIQS
CCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCHHCCCCCHHC
HHTQIHLLQAIYEGVIFSLMSHLERMQVRFPNASTVRVTGGPAKSEVWMQMLADISGMRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCHHHHHHHHHHCCCCCEE
EIPNIEETGCLGAALMAMQAESAVEISQILNIDRKIFLPDKNQYSKYQHKYHRYLKFIEA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
LKNLD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800