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The map label for this gene is suhB

Identifier: 16272874

GI number: 16272874

Start: 996254

End: 997057

Strand: Reverse

Name: suhB

Synonym: HI0937

Alternate gene names: 16272874

Gene position: 997057-996254 (Counterclockwise)

Preceding gene: 16272883

Following gene: 16272873

Centisome position: 54.48

GC content: 39.55

Gene sequence:

>804_bases
ATGAATCCAATGTTAAATATCGCAATTCGTGCGGCACGAAAAGCGGGCAATGTGATTGCTAAAAATTATGAACGCCGTGA
TGCTATCGAAAGCACACAAAAAGGTATTAATGATTATGTAACAAACGTTGATAAAGCGTCTGAAGCAGAAATCATTGAAG
TTATTCGTAAATCTTATCCTGATCACACAATTATTACGGAAGAAACAGGCGCAATTGAAGGCAAAGATAGCGATGTACAA
TGGATTATTGATCCGCTAGATGGTACTCGTAATTTTATGACAGGGCTTCCCCACTTTTCTGTGTCTATCGCAGTTCGTGT
AAAAAATCGCACTGAAGTCGGGGTTGTTTACGATCCAATCCGTAATGAATTATTTACCGCTGTGCGTGGCGAAGGTGCAA
AATTAAATGAAGTACGTTTACGTGTAGATAGTAAACGTGAAATTCAAGGTTCAATTTTAGCCACTGGTTTCCCATTCAAA
CAACCAAAATTAATGCCAGCTCAATTTGCAATGATGAATGCCTTAATTGAAGATGCTGCGGATTTCCGTCGTACTGGTTC
TGCCGCATTGGATTTATGCTATGTGGCGTCAAACCGTATTGATGGTTATTTTGAAATGGGCTTAAAAGCATGGGATTGTG
CTGCTGGCGATTTAATCGTGCGTGAAGCGGGTGGTTTAGTTTGCGATTTTGATGCTGGTAACAGCTACTTACGCAGTGGC
AATATCATTGCTGCACCATCACGCGTAATTAAAGAAATGTTAAATAAAATTCGCCCTTGTTTAGGTGCTGAATTTAATCA
TTAA

Upstream 100 bases:

>100_bases
ACCTATAAAAACCACTGTTTTATGATTTTCAACTAGTTATTTTGGCAAATCTCGCTATAATGGCACGGAATTTTTCTGTT
CTTTAAAAGCTGGTGGAAAT

Downstream 100 bases:

>100_bases
TTTTTATAAGCACAATAGCACCTATCAAGGTGCTATTTTTAATTTTATTAATGAAACATACTTGATTAGCGACTTTATCT
GCGCATCAACGAAAAAAACG

Product: extragenic suppressor

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNPMLNIAIRAARKAGNVIAKNYERRDAIESTQKGINDYVTNVDKASEAEIIEVIRKSYPDHTIITEETGAIEGKDSDVQ
WIIDPLDGTRNFMTGLPHFSVSIAVRVKNRTEVGVVYDPIRNELFTAVRGEGAKLNEVRLRVDSKREIQGSILATGFPFK
QPKLMPAQFAMMNALIEDAADFRRTGSAALDLCYVASNRIDGYFEMGLKAWDCAAGDLIVREAGGLVCDFDAGNSYLRSG
NIIAAPSRVIKEMLNKIRPCLGAEFNH

Sequences:

>Translated_267_residues
MNPMLNIAIRAARKAGNVIAKNYERRDAIESTQKGINDYVTNVDKASEAEIIEVIRKSYPDHTIITEETGAIEGKDSDVQ
WIIDPLDGTRNFMTGLPHFSVSIAVRVKNRTEVGVVYDPIRNELFTAVRGEGAKLNEVRLRVDSKREIQGSILATGFPFK
QPKLMPAQFAMMNALIEDAADFRRTGSAALDLCYVASNRIDGYFEMGLKAWDCAAGDLIVREAGGLVCDFDAGNSYLRSG
NIIAAPSRVIKEMLNKIRPCLGAEFNH
>Mature_267_residues
MNPMLNIAIRAARKAGNVIAKNYERRDAIESTQKGINDYVTNVDKASEAEIIEVIRKSYPDHTIITEETGAIEGKDSDVQ
WIIDPLDGTRNFMTGLPHFSVSIAVRVKNRTEVGVVYDPIRNELFTAVRGEGAKLNEVRLRVDSKREIQGSILATGFPFK
QPKLMPAQFAMMNALIEDAADFRRTGSAALDLCYVASNRIDGYFEMGLKAWDCAAGDLIVREAGGLVCDFDAGNSYLRSG
NIIAAPSRVIKEMLNKIRPCLGAEFNH

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family

Homologues:

Organism=Homo sapiens, GI7657236, Length=254, Percent_Identity=34.6456692913386, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI5031789, Length=257, Percent_Identity=33.852140077821, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI221625487, Length=257, Percent_Identity=33.852140077821, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI221625507, Length=145, Percent_Identity=33.7931034482759, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1788882, Length=261, Percent_Identity=64.7509578544061, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1790659, Length=218, Percent_Identity=26.605504587156, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193202570, Length=236, Percent_Identity=33.4745762711864, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI193202572, Length=233, Percent_Identity=33.0472103004292, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320493, Length=208, Percent_Identity=37.0192307692308, Blast_Score=119, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6321836, Length=238, Percent_Identity=32.3529411764706, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357329, Length=258, Percent_Identity=35.6589147286822, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24664922, Length=265, Percent_Identity=29.811320754717, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21357303, Length=231, Percent_Identity=35.0649350649351, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24664926, Length=227, Percent_Identity=31.7180616740088, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21357957, Length=264, Percent_Identity=29.9242424242424, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24664918, Length=258, Percent_Identity=30.6201550387597, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUHB_HAEIN (P44333)

Other databases:

- EMBL:   L42023
- PIR:   F64103
- RefSeq:   NP_439097.1
- ProteinModelPortal:   P44333
- SMR:   P44333
- GeneID:   949915
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0937
- NMPDR:   fig|71421.1.peg.903
- TIGR:   HI_0937
- HOGENOM:   HBG730251
- OMA:   TGFPFKQ
- ProtClustDB:   CLSK870048
- BioCyc:   HINF71421:HI_0937-MONOMER
- BRENDA:   3.1.3.25
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337
- PANTHER:   PTHR20854
- PRINTS:   PR00377
- PRINTS:   PR01959

Pfam domain/function: PF00459 Inositol_P

EC number: =3.1.3.25

Molecular weight: Translated: 29500; Mature: 29500

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00629 IMP_1; PS00630 IMP_2

Important sites: BINDING 67-67 BINDING 183-183 BINDING 212-212

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPMLNIAIRAARKAGNVIAKNYERRDAIESTQKGINDYVTNVDKASEAEIIEVIRKSYP
CCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
DHTIITEETGAIEGKDSDVQWIIDPLDGTRNFMTGLPHFSVSIAVRVKNRTEVGVVYDPI
CCEEEECCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCEEEEEECHH
RNELFTAVRGEGAKLNEVRLRVDSKREIQGSILATGFPFKQPKLMPAQFAMMNALIEDAA
HHHHHHHHCCCCCEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHH
DFRRTGSAALDLCYVASNRIDGYFEMGLKAWDCAAGDLIVREAGGLVCDFDAGNSYLRSG
HHHHCCHHHHHHHHHHCCCCCCHHHHCCEEECCCCCCEEEECCCCEEEEECCCCCEEECC
NIIAAPSRVIKEMLNKIRPCLGAEFNH
CEEECCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNPMLNIAIRAARKAGNVIAKNYERRDAIESTQKGINDYVTNVDKASEAEIIEVIRKSYP
CCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
DHTIITEETGAIEGKDSDVQWIIDPLDGTRNFMTGLPHFSVSIAVRVKNRTEVGVVYDPI
CCEEEECCCCCCCCCCCCCEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCEEEEEECHH
RNELFTAVRGEGAKLNEVRLRVDSKREIQGSILATGFPFKQPKLMPAQFAMMNALIEDAA
HHHHHHHHCCCCCEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHH
DFRRTGSAALDLCYVASNRIDGYFEMGLKAWDCAAGDLIVREAGGLVCDFDAGNSYLRSG
HHHHCCHHHHHHHHHHCCCCCCHHHHCCEEECCCCCCEEEECCCCEEEEECCCCCEEECC
NIIAAPSRVIKEMLNKIRPCLGAEFNH
CEEECCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800