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The map label for this gene is nrfE

Identifier: 16272873

GI number: 16272873

Start: 994238

End: 996145

Strand: Reverse

Name: nrfE

Synonym: HI0936

Alternate gene names: 16272873

Gene position: 996145-994238 (Counterclockwise)

Preceding gene: 16272874

Following gene: 16272872

Centisome position: 54.43

GC content: 40.62

Gene sequence:

>1908_bases
ATGCTTCCAGAACTTGGCTTTTTCCTTCTTTTACTCGCAACAGCTAGCGCGTTTTTCCTTGCGTTAGTGCCTCAATTTGG
GTTATTCAAAAAAAATCCGACTTTAATTAATGCTGCTTGGCCGCTTAGTTATATTTTTACCCTTGCGACGACGTTATCAA
TTGGTTTGCTTGCTTATTCTTTTGCGGTGGATGATTTCACCCTTGAATATGTAGCGGCACATTCTAATTCCCAATTACCT
ACATTTTTTAAAGTGGCTGCCACTTGGGGAGGACATGAAGGTTCAATGTTGTTTTGGTTATTTTCATTGAGTTTATGGCT
TGCTGCTTTTGCTTTTTTTAATCGAAAAAATGACCGCACTTTTTCTGCTCAATCTTTATCTTTATTGGGATTGATTTGCT
TTGGTTTTGCGGTGTTTATTTTATTTTATTCCAATCCATTTGGACGCATTTTCCCAGCACCCGCAGAAGGGCGCGATCTC
AATCCAATGTTGCAAGATGTGGGATTAATTTTCCATCCACCTTTACTATATGTTGGCTATGTGGGCTTTGCGGTAAATTT
TGCAATGAGTTTGAGTGCGTTGATTTATAACCAATCTGCACGACAAATTGCCCGCTCAATGCGTGGATGGGTGTTGGTTT
CTTGGTTATTTTTAACCATTGGCATTGTGCTTGGTGCTTGGTGGGCTTATTACGAACTTGGCTGGGGCGGTTGGTGGTTC
TGGGATCCCGTAGAAAATGCGTCTTTAATGCCTTGGTTGCTTGGTTTGGCATTATTACACAGTTTAATGGCGACGGAAAA
ACAAGGCGTATTTAGTTATTGGACAACGCTTTTTTCTCTGCTTGCTTTTGCCTTTAGCGTATTAGGCACGTTTATTGTTC
GTTCTGGCGCACTCACTTCTGTGCATGCTTTTGCATTGGATAACACGCGCGGTTATGTGTTGTTATTAATTTTCTTTGTT
TTGACAGCGTTAGCCTTTGGTTTATTCGCTTTACGAGCGGGAAGTTCATCAGAAAGTGCGGTGAAATTTCAGTTCATTTC
TAAATCGGGTGGCATTTTATTACTGAATATTTTGCTGACCATTGCGACGGTTTCTACCTTTTTAGGTACCTTTTACCCGA
TGTTATTCCAAGCGATGAATTGGGGCTCAATTTCGGTGGGAAGTCCTTATTTTAATAGTATTTTCTTCCCCATTATTACG
GCGATTTTAATCTTAATGGTAATTGTGCTTAGCATACGTAAGGGGCAATTTGATCGCACATTATTGATACGTTGTGGGTG
GTTGCTTATTCCGTCTTTAATTCTTGCAGGCCTAATGATTTGGCAACAGCTACGAAATAATTCTGCATTACATTTCCATG
CTTTCGCCTTTGTGTTATTAACTCTTGCGATTTGGCTTTTATTCGTCACGTTATGGCAAAATTGGCGACAAATTCGCTTG
TCTCAATTTGGGATGATTTTAGCACACTGTGGCGTGGCGATTGTGACTATTGGTGCGGTGATGAGTGGGTATTTTGGCAG
TGAAATTGGTGTGCGTTTAGCACCGCAACAAAGTCAAACGTTAGGGCAATATGAATTTCATTATCGCCAATTTTCTAATG
AAATTGGGCCAAACTTTACGGCAGAAGTCGCCTTTTTTGACGTAACTAAAAATGGTAAACCTTATGCAGAAATTATCCCA
GAACGCCGTTATTACGATGTACGAACAATGACAATGAGTGAAGTGGGGCTTGATGGTGGTTTTTGGGGCGATTTATATAT
TGTGATGGGCGATTCTCTTGGCAAAGGGGAATTTACTTTCCGCTTACATTATAAACCACTGATTCGTTGGCTTTGGGCGG
GCGGTATTTTAATGGCCTTTGGCGCACTTTTTAGCGTTTTCGGATTACGCAGAAAACAGGAAAAATAA

Upstream 100 bases:

>100_bases
AGCACAATAGCACCTATCAAGGTGCTATTTTTAATTTTATTAATGAAACATACTTGATTAGCGACTTTATCTGCGCATCA
ACGAAAAAAACGACGACATT

Downstream 100 bases:

>100_bases
TGAACAAAAAACTTATCTTTTTTACACCGCTCTTTGTGCTTTTAGGCGTGTGTATATTATTAATTGCAGGGTTAAATCAA
GATCCGAAAAAAATTGCGTC

Product: cytochrome C-type biogenesis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MLPELGFFLLLLATASAFFLALVPQFGLFKKNPTLINAAWPLSYIFTLATTLSIGLLAYSFAVDDFTLEYVAAHSNSQLP
TFFKVAATWGGHEGSMLFWLFSLSLWLAAFAFFNRKNDRTFSAQSLSLLGLICFGFAVFILFYSNPFGRIFPAPAEGRDL
NPMLQDVGLIFHPPLLYVGYVGFAVNFAMSLSALIYNQSARQIARSMRGWVLVSWLFLTIGIVLGAWWAYYELGWGGWWF
WDPVENASLMPWLLGLALLHSLMATEKQGVFSYWTTLFSLLAFAFSVLGTFIVRSGALTSVHAFALDNTRGYVLLLIFFV
LTALAFGLFALRAGSSSESAVKFQFISKSGGILLLNILLTIATVSTFLGTFYPMLFQAMNWGSISVGSPYFNSIFFPIIT
AILILMVIVLSIRKGQFDRTLLIRCGWLLIPSLILAGLMIWQQLRNNSALHFHAFAFVLLTLAIWLLFVTLWQNWRQIRL
SQFGMILAHCGVAIVTIGAVMSGYFGSEIGVRLAPQQSQTLGQYEFHYRQFSNEIGPNFTAEVAFFDVTKNGKPYAEIIP
ERRYYDVRTMTMSEVGLDGGFWGDLYIVMGDSLGKGEFTFRLHYKPLIRWLWAGGILMAFGALFSVFGLRRKQEK

Sequences:

>Translated_635_residues
MLPELGFFLLLLATASAFFLALVPQFGLFKKNPTLINAAWPLSYIFTLATTLSIGLLAYSFAVDDFTLEYVAAHSNSQLP
TFFKVAATWGGHEGSMLFWLFSLSLWLAAFAFFNRKNDRTFSAQSLSLLGLICFGFAVFILFYSNPFGRIFPAPAEGRDL
NPMLQDVGLIFHPPLLYVGYVGFAVNFAMSLSALIYNQSARQIARSMRGWVLVSWLFLTIGIVLGAWWAYYELGWGGWWF
WDPVENASLMPWLLGLALLHSLMATEKQGVFSYWTTLFSLLAFAFSVLGTFIVRSGALTSVHAFALDNTRGYVLLLIFFV
LTALAFGLFALRAGSSSESAVKFQFISKSGGILLLNILLTIATVSTFLGTFYPMLFQAMNWGSISVGSPYFNSIFFPIIT
AILILMVIVLSIRKGQFDRTLLIRCGWLLIPSLILAGLMIWQQLRNNSALHFHAFAFVLLTLAIWLLFVTLWQNWRQIRL
SQFGMILAHCGVAIVTIGAVMSGYFGSEIGVRLAPQQSQTLGQYEFHYRQFSNEIGPNFTAEVAFFDVTKNGKPYAEIIP
ERRYYDVRTMTMSEVGLDGGFWGDLYIVMGDSLGKGEFTFRLHYKPLIRWLWAGGILMAFGALFSVFGLRRKQEK
>Mature_635_residues
MLPELGFFLLLLATASAFFLALVPQFGLFKKNPTLINAAWPLSYIFTLATTLSIGLLAYSFAVDDFTLEYVAAHSNSQLP
TFFKVAATWGGHEGSMLFWLFSLSLWLAAFAFFNRKNDRTFSAQSLSLLGLICFGFAVFILFYSNPFGRIFPAPAEGRDL
NPMLQDVGLIFHPPLLYVGYVGFAVNFAMSLSALIYNQSARQIARSMRGWVLVSWLFLTIGIVLGAWWAYYELGWGGWWF
WDPVENASLMPWLLGLALLHSLMATEKQGVFSYWTTLFSLLAFAFSVLGTFIVRSGALTSVHAFALDNTRGYVLLLIFFV
LTALAFGLFALRAGSSSESAVKFQFISKSGGILLLNILLTIATVSTFLGTFYPMLFQAMNWGSISVGSPYFNSIFFPIIT
AILILMVIVLSIRKGQFDRTLLIRCGWLLIPSLILAGLMIWQQLRNNSALHFHAFAFVLLTLAIWLLFVTLWQNWRQIRL
SQFGMILAHCGVAIVTIGAVMSGYFGSEIGVRLAPQQSQTLGQYEFHYRQFSNEIGPNFTAEVAFFDVTKNGKPYAEIIP
ERRYYDVRTMTMSEVGLDGGFWGDLYIVMGDSLGKGEFTFRLHYKPLIRWLWAGGILMAFGALFSVFGLRRKQEK

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family

Homologues:

Organism=Escherichia coli, GI1788524, Length=641, Percent_Identity=40.5616224648986, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1790511, Length=580, Percent_Identity=37.4137931034483, Blast_Score=331, Evalue=9e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRFE_HAEIN (P44944)

Other databases:

- EMBL:   L42023
- PIR:   A64162
- RefSeq:   NP_439096.1
- GeneID:   950731
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0936
- NMPDR:   fig|71421.1.peg.902
- TIGR:   HI_0936
- HOGENOM:   HBG663906
- OMA:   GPDRYAM
- ProtClustDB:   CLSK869939
- BioCyc:   HINF71421:HI_0936-MONOMER
- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568
- InterPro:   IPR003570
- InterPro:   IPR017563
- PRINTS:   PR01410
- PRINTS:   PR01413
- TIGRFAMs:   TIGR03145
- TIGRFAMs:   TIGR00353

Pfam domain/function: PF01578 Cytochrom_C_asm

EC number: NA

Molecular weight: Translated: 71275; Mature: 71275

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdab6414)-; HASH(0xb45da80)-; HASH(0xd5cb0c4)-; HASH(0xd919988)-; HASH(0xbbd6bf0)-; HASH(0xd82a510)-; HASH(0xcbbcb0c)-; HASH(0xdabe55c)-; HASH(0xce69774)-; HASH(0xdb42880)-; HASH(0xd14ff3c)-; HASH(0xda5d408)-; HASH(0xdb31e6c)-; HASH(0xdac16e8)-; HASH(0xdaf6cf0)-; HASH(0xd83db5c)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPELGFFLLLLATASAFFLALVPQFGLFKKNPTLINAAWPLSYIFTLATTLSIGLLAYS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
FAVDDFTLEYVAAHSNSQLPTFFKVAATWGGHEGSMLFWLFSLSLWLAAFAFFNRKNDRT
HHHCCHHHHHHEECCCCCCCHHHEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
FSAQSLSLLGLICFGFAVFILFYSNPFGRIFPAPAEGRDLNPMLQDVGLIFHPPLLYVGY
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCHHHCCHHHHHHH
VGFAVNFAMSLSALIYNQSARQIARSMRGWVLVSWLFLTIGIVLGAWWAYYELGWGGWWF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
WDPVENASLMPWLLGLALLHSLMATEKQGVFSYWTTLFSLLAFAFSVLGTFIVRSGALTS
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VHAFALDNTRGYVLLLIFFVLTALAFGLFALRAGSSSESAVKFQFISKSGGILLLNILLT
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHH
IATVSTFLGTFYPMLFQAMNWGSISVGSPYFNSIFFPIITAILILMVIVLSIRKGQFDRT
HHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
LLIRCGWLLIPSLILAGLMIWQQLRNNSALHFHAFAFVLLTLAIWLLFVTLWQNWRQIRL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQFGMILAHCGVAIVTIGAVMSGYFGSEIGVRLAPQQSQTLGQYEFHYRQFSNEIGPNFT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCE
AEVAFFDVTKNGKPYAEIIPERRYYDVRTMTMSEVGLDGGFWGDLYIVMGDSLGKGEFTF
EEEEEEEECCCCCCHHHHCCCCCEEEEHEEEHHHHCCCCCCCCEEEEEEECCCCCCEEEE
RLHYKPLIRWLWAGGILMAFGALFSVFGLRRKQEK
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLPELGFFLLLLATASAFFLALVPQFGLFKKNPTLINAAWPLSYIFTLATTLSIGLLAYS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHH
FAVDDFTLEYVAAHSNSQLPTFFKVAATWGGHEGSMLFWLFSLSLWLAAFAFFNRKNDRT
HHHCCHHHHHHEECCCCCCCHHHEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
FSAQSLSLLGLICFGFAVFILFYSNPFGRIFPAPAEGRDLNPMLQDVGLIFHPPLLYVGY
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCHHHCCHHHHHHH
VGFAVNFAMSLSALIYNQSARQIARSMRGWVLVSWLFLTIGIVLGAWWAYYELGWGGWWF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
WDPVENASLMPWLLGLALLHSLMATEKQGVFSYWTTLFSLLAFAFSVLGTFIVRSGALTS
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VHAFALDNTRGYVLLLIFFVLTALAFGLFALRAGSSSESAVKFQFISKSGGILLLNILLT
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHH
IATVSTFLGTFYPMLFQAMNWGSISVGSPYFNSIFFPIITAILILMVIVLSIRKGQFDRT
HHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
LLIRCGWLLIPSLILAGLMIWQQLRNNSALHFHAFAFVLLTLAIWLLFVTLWQNWRQIRL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQFGMILAHCGVAIVTIGAVMSGYFGSEIGVRLAPQQSQTLGQYEFHYRQFSNEIGPNFT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCE
AEVAFFDVTKNGKPYAEIIPERRYYDVRTMTMSEVGLDGGFWGDLYIVMGDSLGKGEFTF
EEEEEEEECCCCCCHHHHCCCCCEEEEHEEEHHHHCCCCCCCCEEEEEEECCCCCCEEEE
RLHYKPLIRWLWAGGILMAFGALFSVFGLRRKQEK
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800