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The map label for this gene is cdsA

Identifier: 16272856

GI number: 16272856

Start: 975293

End: 976159

Strand: Reverse

Name: cdsA

Synonym: HI0919

Alternate gene names: 16272856

Gene position: 976159-975293 (Counterclockwise)

Preceding gene: 16272857

Following gene: 16272855

Centisome position: 53.34

GC content: 37.95

Gene sequence:

>867_bases
ATGCTTAAACAACGAGTTTTATCTGCTATTGTGTTAATTGCTGCAGTTTTATGTGCGCTATTTTTATTCACACCTTTTTA
TTTTGCCCTCGCTTTAGGGGCAGTAGCGATTTTAGGCATTTGGGAATGGACTCAATTTGCTCGCCTAAAACAACCTTTGA
TACGTTTTTTTGTGACTACCTTTTTAGGCGTATTTATCTTCTTATGGCTCTATACTGAGGGCAACTATTTAGATGCAGGG
CGTGTGTTTGAACAACATCTTCAGCTTTTATTGATAAATGCTGTTAGCTGGTGGGGTTTAGCTTTGTTACTTGTGATCAG
TTACCCTAAATCAGCTAAATTTTGGTCTAAAAATCCACTTTTACAACTTTTATTTGCCTTTTCTACGTTGATTCCATTTG
TCGCAGGTGTATTACGTTTACGTTTAGAACACTATACCCATGATCCTTATCACGGCTTATTTTTATTACTTTACGTATTT
ATACTTGTTTGGGCGGCTGATTCTGGTGCTTATTTTAGCGGACGCGCCTTTGGCAAACGTAAACTTGCCCCTAAAGTATC
GCCAGGTAAAAGTTGGGAAGGGGTCATTGGTGGCTTAATTACAGCATTAGTGCTTGCTTTTATCTTTATTCATTTCTCTA
ACAATACTTTAGTAGGCGATCGAAATATTACTGGATTTATCATTCTTTCTGTAGCCACAGTTGCAATTTCAGTATTGGGC
GATTTAACTGAAAGTATGTTTAAACGTGAGTCAGGAGTTAAAGACAGCAGTCAATTAATTCCAGGTCACGGCGGCGTATT
AGATCGCATTGACAGCTTGACTGCCGCGGTACCTTTTTTCAGCTATTTCTATTTCTTTGTCTTATAA

Upstream 100 bases:

>100_bases
GGCCTGATTTTAATCAATTAGAATTTAATCGCGCGATTGCAAGTTATCAACAACGTCATCGCCGTTTTGGCGGGACTGAA
TAGTTAAACGGATTAAAATT

Downstream 100 bases:

>100_bases
GGATTTTTAATGTCATTTTTGTGGTCACTAGGTTCTTTTATCATTGCTATTGCTGTATTAGTATCCGTTCACGAATATGG
TCACTTTTGGGCAGCGAGAA

Product: CDP-diglyceride synthetase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MLKQRVLSAIVLIAAVLCALFLFTPFYFALALGAVAILGIWEWTQFARLKQPLIRFFVTTFLGVFIFLWLYTEGNYLDAG
RVFEQHLQLLLINAVSWWGLALLLVISYPKSAKFWSKNPLLQLLFAFSTLIPFVAGVLRLRLEHYTHDPYHGLFLLLYVF
ILVWAADSGAYFSGRAFGKRKLAPKVSPGKSWEGVIGGLITALVLAFIFIHFSNNTLVGDRNITGFIILSVATVAISVLG
DLTESMFKRESGVKDSSQLIPGHGGVLDRIDSLTAAVPFFSYFYFFVL

Sequences:

>Translated_288_residues
MLKQRVLSAIVLIAAVLCALFLFTPFYFALALGAVAILGIWEWTQFARLKQPLIRFFVTTFLGVFIFLWLYTEGNYLDAG
RVFEQHLQLLLINAVSWWGLALLLVISYPKSAKFWSKNPLLQLLFAFSTLIPFVAGVLRLRLEHYTHDPYHGLFLLLYVF
ILVWAADSGAYFSGRAFGKRKLAPKVSPGKSWEGVIGGLITALVLAFIFIHFSNNTLVGDRNITGFIILSVATVAISVLG
DLTESMFKRESGVKDSSQLIPGHGGVLDRIDSLTAAVPFFSYFYFFVL
>Mature_288_residues
MLKQRVLSAIVLIAAVLCALFLFTPFYFALALGAVAILGIWEWTQFARLKQPLIRFFVTTFLGVFIFLWLYTEGNYLDAG
RVFEQHLQLLLINAVSWWGLALLLVISYPKSAKFWSKNPLLQLLFAFSTLIPFVAGVLRLRLEHYTHDPYHGLFLLLYVF
ILVWAADSGAYFSGRAFGKRKLAPKVSPGKSWEGVIGGLITALVLAFIFIHFSNNTLVGDRNITGFIILSVATVAISVLG
DLTESMFKRESGVKDSSQLIPGHGGVLDRIDSLTAAVPFFSYFYFFVL

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family

Homologues:

Organism=Escherichia coli, GI87081696, Length=287, Percent_Identity=47.0383275261324, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1787677, Length=119, Percent_Identity=41.1764705882353, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDSA_HAEIN (P44937)

Other databases:

- EMBL:   L42023
- EMBL:   U60831
- EMBL:   U60832
- PIR:   G64102
- RefSeq:   NP_439079.1
- GeneID:   949391
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0919
- NMPDR:   fig|71421.1.peg.885
- TIGR:   HI_0919
- HOGENOM:   HBG732679
- OMA:   LEHYTHD
- ProtClustDB:   CLSK870687
- BioCyc:   HINF71421:HI_0919-MONOMER
- BRENDA:   2.7.7.41
- InterPro:   IPR000374

Pfam domain/function: PF01148 CTP_transf_1

EC number: =2.7.7.41

Molecular weight: Translated: 32248; Mature: 32248

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xda4a28c)-; HASH(0xdb2476c)-; HASH(0xd08ef78)-; HASH(0xc7102b4)-; HASH(0xc905a90)-; HASH(0xd561f9c)-; HASH(0xd3f6d04)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure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HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800