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The map label for this gene is yaeL [C]

Identifier: 16272855

GI number: 16272855

Start: 973952

End: 975283

Strand: Reverse

Name: yaeL [C]

Synonym: HI0918

Alternate gene names: 16272855

Gene position: 975283-973952 (Counterclockwise)

Preceding gene: 16272856

Following gene: 16272854

Centisome position: 53.29

GC content: 35.66

Gene sequence:

>1332_bases
ATGTCATTTTTGTGGTCACTAGGTTCTTTTATCATTGCTATTGCTGTATTAGTATCCGTTCACGAATATGGTCACTTTTG
GGCAGCGAGAAAGTGCGGTATAAAAGTCCATCGTTTTTCCATTGGTTTTGGAAAAGTAATTTGGAAACGCATTGACAAAT
ATGGTACAGAATTTGCGGTTTCAATGATTCCTTTAGGCGGCTATGTAAAAATGCTTGATGGACGTAATGAAGTAGTTCCT
GCTGAGCAAAAATCACAAGCATTTGACAGTAAAAGCGTATTACAACGGTCATTTGTAATTATTGCAGGCCCTTTAGCTAA
TTTTATTTTTGCAATTTTTGCTTATTGGGTCATTTACCTTTATGGAATGCCAACGGTTAAACCAGTGATTGAATCAATAA
CACCAAACTCAATCGCAGCACAAGCCCACATTGAACCCAATACGCAAATTCTTACAATTGATGGCGAAGAAACTCAAGAT
TGGGAAACCATCAATATGCTACTTGCCACAAAAATGGGGGAGCCTAATGTTGAGATTAGCCTTTCTCCTTTCAATTCTAA
TATTGAACAACAACGGACTTTAAATCTTACAAATTGGACATTCGATCCTGAAAAAGAAAGTGCTTTTGAGGCATTAGGGA
TTATGCCTATGCGTCCTAAAATTGAAATGGTGCTTTCTAAAGTTGTTCAAAATTCTCCCGCTGAGAAAGCTGGTTTACAA
ATCGGTGATAAAATTTTAAAAGAAAATTTAACCGCACTTCCTTGGCAAGATTTTATAAAACAGGTCGAACAAGGCGAATC
TTTTTCTATTAAAGTTGAACGTAATGGAGAAACATTTGACAAAGTCCTAACTCCAGTGCGTAATCAAAATGGCAAATGGT
TTGTTGGGGTTAGCCCAGCCTTAACAAAATTAGCGGATGAATACCGTACTGAATTAAAATATGGTATTCTTGAATCTTTA
CAAAAAGGCATTGAAAAAACAGGACAGCTTTCCCTTTTAACCTTGAAAATATTAGGGAAATTACTTACTGGCGATTTGTC
ATTAAATAATTTAAGTGGGCCAATTTCTATTGCAAAAGGTGCTGGCGCATCAGCAAATATTGGATTGGTGTATTTTTTAA
GTTTTATGGCATTGATTAGTGTAAATTTAGGGATTATGAATTTATTTCCATTACCAGTATTAGATGGCGGTCATTTAGTT
TTTTTAACAATGGAAGCTGTTAAAGGAAAACCTGTTTCTGAGCGGGTGCAAAGCATCTGTTATCGAATTGGCGCAGCACT
GTTATTAAGCTTAACGGTGTTTGCATTATTTAATGATTTTTTACGTCTATAA

Upstream 100 bases:

>100_bases
AATTCCAGGTCACGGCGGCGTATTAGATCGCATTGACAGCTTGACTGCCGCGGTACCTTTTTTCAGCTATTTCTATTTCT
TTGTCTTATAAGGATTTTTA

Downstream 100 bases:

>100_bases
TTTATATAGGATACAATCGATGAAAAAACTTCTAATCGCAAGTTTATTATTCGGTACGACAACGACTGTGTTTGCCGCAC
CTTTTGTGGCAAAAGATATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSFLWSLGSFIIAIAVLVSVHEYGHFWAARKCGIKVHRFSIGFGKVIWKRIDKYGTEFAVSMIPLGGYVKMLDGRNEVVP
AEQKSQAFDSKSVLQRSFVIIAGPLANFIFAIFAYWVIYLYGMPTVKPVIESITPNSIAAQAHIEPNTQILTIDGEETQD
WETINMLLATKMGEPNVEISLSPFNSNIEQQRTLNLTNWTFDPEKESAFEALGIMPMRPKIEMVLSKVVQNSPAEKAGLQ
IGDKILKENLTALPWQDFIKQVEQGESFSIKVERNGETFDKVLTPVRNQNGKWFVGVSPALTKLADEYRTELKYGILESL
QKGIEKTGQLSLLTLKILGKLLTGDLSLNNLSGPISIAKGAGASANIGLVYFLSFMALISVNLGIMNLFPLPVLDGGHLV
FLTMEAVKGKPVSERVQSICYRIGAALLLSLTVFALFNDFLRL

Sequences:

>Translated_443_residues
MSFLWSLGSFIIAIAVLVSVHEYGHFWAARKCGIKVHRFSIGFGKVIWKRIDKYGTEFAVSMIPLGGYVKMLDGRNEVVP
AEQKSQAFDSKSVLQRSFVIIAGPLANFIFAIFAYWVIYLYGMPTVKPVIESITPNSIAAQAHIEPNTQILTIDGEETQD
WETINMLLATKMGEPNVEISLSPFNSNIEQQRTLNLTNWTFDPEKESAFEALGIMPMRPKIEMVLSKVVQNSPAEKAGLQ
IGDKILKENLTALPWQDFIKQVEQGESFSIKVERNGETFDKVLTPVRNQNGKWFVGVSPALTKLADEYRTELKYGILESL
QKGIEKTGQLSLLTLKILGKLLTGDLSLNNLSGPISIAKGAGASANIGLVYFLSFMALISVNLGIMNLFPLPVLDGGHLV
FLTMEAVKGKPVSERVQSICYRIGAALLLSLTVFALFNDFLRL
>Mature_442_residues
SFLWSLGSFIIAIAVLVSVHEYGHFWAARKCGIKVHRFSIGFGKVIWKRIDKYGTEFAVSMIPLGGYVKMLDGRNEVVPA
EQKSQAFDSKSVLQRSFVIIAGPLANFIFAIFAYWVIYLYGMPTVKPVIESITPNSIAAQAHIEPNTQILTIDGEETQDW
ETINMLLATKMGEPNVEISLSPFNSNIEQQRTLNLTNWTFDPEKESAFEALGIMPMRPKIEMVLSKVVQNSPAEKAGLQI
GDKILKENLTALPWQDFIKQVEQGESFSIKVERNGETFDKVLTPVRNQNGKWFVGVSPALTKLADEYRTELKYGILESLQ
KGIEKTGQLSLLTLKILGKLLTGDLSLNNLSGPISIAKGAGASANIGLVYFLSFMALISVNLGIMNLFPLPVLDGGHLVF
LTMEAVKGKPVSERVQSICYRIGAALLLSLTVFALFNDFLRL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1786373, Length=449, Percent_Identity=53.4521158129176, Blast_Score=483, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y918_HAEIN (P44936)

Other databases:

- EMBL:   L42023
- PIR:   D64161
- RefSeq:   NP_439078.1
- ProteinModelPortal:   P44936
- SMR:   P44936
- MEROPS:   M50.004
- GeneID:   949920
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0918
- NMPDR:   fig|71421.1.peg.884
- TIGR:   HI_0918
- HOGENOM:   HBG664087
- OMA:   HGTEFVV
- ProtClustDB:   CLSK870688
- BioCyc:   HINF71421:HI_0918-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915
- SMART:   SM00228
- TIGRFAMs:   TIGR00054

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50; SSF50156 PDZ

EC number: NA

Molecular weight: Translated: 49071; Mature: 48940

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS50106 PDZ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 22-22

Signals:

None

Transmembrane regions:

HASH(0xcacd338)-; HASH(0xd618a1c)-; HASH(0xc7d1794)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLWSLGSFIIAIAVLVSVHEYGHFWAARKCGIKVHRFSIGFGKVIWKRIDKYGTEFAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCHHEE
SMIPLGGYVKMLDGRNEVVPAEQKSQAFDSKSVLQRSFVIIAGPLANFIFAIFAYWVIYL
EEECCCCEEEEECCCCCCCCCHHHHHHCCHHHHHHHHHEEEECHHHHHHHHHHHHHHHHH
YGMPTVKPVIESITPNSIAAQAHIEPNTQILTIDGEETQDWETINMLLATKMGEPNVEIS
HCCCHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEE
LSPFNSNIEQQRTLNLTNWTFDPEKESAFEALGIMPMRPKIEMVLSKVVQNSPAEKAGLQ
ECCCCCCCCHHHEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHH
IGDKILKENLTALPWQDFIKQVEQGESFSIKVERNGETFDKVLTPVRNQNGKWFVGVSPA
HHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEECCHH
LTKLADEYRTELKYGILESLQKGIEKTGQLSLLTLKILGKLLTGDLSLNNLSGPISIAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
AGASANIGLVYFLSFMALISVNLGIMNLFPLPVLDGGHLVFLTMEAVKGKPVSERVQSIC
CCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCEECCCEEEEEEEEHHCCCCHHHHHHHHH
YRIGAALLLSLTVFALFNDFLRL
HHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
SFLWSLGSFIIAIAVLVSVHEYGHFWAARKCGIKVHRFSIGFGKVIWKRIDKYGTEFAV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCHHEE
SMIPLGGYVKMLDGRNEVVPAEQKSQAFDSKSVLQRSFVIIAGPLANFIFAIFAYWVIYL
EEECCCCEEEEECCCCCCCCCHHHHHHCCHHHHHHHHHEEEECHHHHHHHHHHHHHHHHH
YGMPTVKPVIESITPNSIAAQAHIEPNTQILTIDGEETQDWETINMLLATKMGEPNVEIS
HCCCHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEE
LSPFNSNIEQQRTLNLTNWTFDPEKESAFEALGIMPMRPKIEMVLSKVVQNSPAEKAGLQ
ECCCCCCCCHHHEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHH
IGDKILKENLTALPWQDFIKQVEQGESFSIKVERNGETFDKVLTPVRNQNGKWFVGVSPA
HHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEECCHH
LTKLADEYRTELKYGILESLQKGIEKTGQLSLLTLKILGKLLTGDLSLNNLSGPISIAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
AGASANIGLVYFLSFMALISVNLGIMNLFPLPVLDGGHLVFLTMEAVKGKPVSERVQSIC
CCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCEECCCEEEEEEEEHHCCCCHHHHHHHHH
YRIGAALLLSLTVFALFNDFLRL
HHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800