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The map label for this gene is obgE [H]

Identifier: 16272817

GI number: 16272817

Start: 929904

End: 931076

Strand: Reverse

Name: obgE [H]

Synonym: HI0877

Alternate gene names: 16272817

Gene position: 931076-929904 (Counterclockwise)

Preceding gene: 16272818

Following gene: 16272815

Centisome position: 50.87

GC content: 41.43

Gene sequence:

>1173_bases
ATGAAATTTATTGATGAATCCCTTATTCGAATTGAGGCTGGGGATGGTGGTAACGGTTGCGTAAGTTTCCGTCGAGAGAA
ATTTATTCCGAAAGGCGGCCCTGATGGTGGCGACGGTGGCGATGGTGGCGATGTCTATTTACAAGCCGATGAAAACCTCA
ATACCTTAATCGATTATCGCTTTAATAAACGCTTTGCCGCAGAGCGTGGAGAGAATGGACGGAGTTCAGATTGTACAGGA
CGTCGCGGTAAAGATATTATTTTACCTGTTCCCGTGGGAACTCGTGCTATTGATAACGACACCAAAGAAACCTTGGGGGA
TTTAACCCAACATGGTCAAAAAATGTTGGTAGCCAAAGGTGGTTATCACGGTTTAGGGAATACTCGTTTCAAATCATCAG
TAAACCGTGCACCGCGTCAAAAAACAATGGGTACGCCGGGCGAAAAACGCGATTTATTATTGGAATTAATGCTACTTGCT
GATGTGGGAATGCTCGGTTTACCTAATGCTGGTAAATCCACTTTTATTCGTGCCGTTTCAGCAGCCAAACCAAAAGTTGC
AGATTATCCATTTACTACCTTAGTACCAAGTCTCGGTGTTGTAAAAGTGGATGACTCACACAGTTTCGTAGTCGCTGATA
TTCCCGGATTAATTGAGGGCGCAGCAGATGGTGCTGGGTTAGGAATTCGTTTTTTAAAACATCTAGAACGTTGTAGAGTG
CTTATTCATTTAGTCGATATTGCGCCAATTGATGGCTCTAATCCAGCAGATAATATGGCTATTATTGAATCTGAACTTTT
CCAATACAGTGAAAAATTATCAGAAAAGCCACGTTGGTTAGTATTCAATAAAATTGATACGATGAGCGATGAAGAAGCTG
AAGAGCGAGCCAGAGAAATTGCTGAACAATTAGGTTGGGAAGAAGATTATTACTTCATTTCAGCGGCAACAGGGAAAAAT
GTTTCTCCACTTTGTCGTGATATTATGGACTTTATCATCGCAAATCCTCGCGAAGCTGAAACACAACAAGTTGCACCTGA
AGAAGTAAAATTCAAATGGGAAGATTATCATCAAGAACGACTAGCAGAGCATCAATTTGATGATGACGAAGATTGGGATG
ATGATTGGAGCGAAGAAGACGATGAAGGAATTGAGTTCATCTATAAACCTTAA

Upstream 100 bases:

>100_bases
CGCATTTGTTGTAGTATGCGGAGCAATTTTATCCGCAATTGGACATAAATTATTACCGCATAAAAATCATTAAAGTGCGG
TTTATTTTGGAGAAGTTTTA

Downstream 100 bases:

>100_bases
GAAAGTCTAATTTTGTAAGCATTAAAAATTTAAAAGCACCTAAAATTTTTAGGTGCTTTTTGCTATTAATTAACGCTCAA
AAATTTCAGAATTAGTAAAG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKFIDESLIRIEAGDGGNGCVSFRREKFIPKGGPDGGDGGDGGDVYLQADENLNTLIDYRFNKRFAAERGENGRSSDCTG
RRGKDIILPVPVGTRAIDNDTKETLGDLTQHGQKMLVAKGGYHGLGNTRFKSSVNRAPRQKTMGTPGEKRDLLLELMLLA
DVGMLGLPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVKVDDSHSFVVADIPGLIEGAADGAGLGIRFLKHLERCRV
LIHLVDIAPIDGSNPADNMAIIESELFQYSEKLSEKPRWLVFNKIDTMSDEEAEERAREIAEQLGWEEDYYFISAATGKN
VSPLCRDIMDFIIANPREAETQQVAPEEVKFKWEDYHQERLAEHQFDDDEDWDDDWSEEDDEGIEFIYKP

Sequences:

>Translated_390_residues
MKFIDESLIRIEAGDGGNGCVSFRREKFIPKGGPDGGDGGDGGDVYLQADENLNTLIDYRFNKRFAAERGENGRSSDCTG
RRGKDIILPVPVGTRAIDNDTKETLGDLTQHGQKMLVAKGGYHGLGNTRFKSSVNRAPRQKTMGTPGEKRDLLLELMLLA
DVGMLGLPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVKVDDSHSFVVADIPGLIEGAADGAGLGIRFLKHLERCRV
LIHLVDIAPIDGSNPADNMAIIESELFQYSEKLSEKPRWLVFNKIDTMSDEEAEERAREIAEQLGWEEDYYFISAATGKN
VSPLCRDIMDFIIANPREAETQQVAPEEVKFKWEDYHQERLAEHQFDDDEDWDDDWSEEDDEGIEFIYKP
>Mature_390_residues
MKFIDESLIRIEAGDGGNGCVSFRREKFIPKGGPDGGDGGDGGDVYLQADENLNTLIDYRFNKRFAAERGENGRSSDCTG
RRGKDIILPVPVGTRAIDNDTKETLGDLTQHGQKMLVAKGGYHGLGNTRFKSSVNRAPRQKTMGTPGEKRDLLLELMLLA
DVGMLGLPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVKVDDSHSFVVADIPGLIEGAADGAGLGIRFLKHLERCRV
LIHLVDIAPIDGSNPADNMAIIESELFQYSEKLSEKPRWLVFNKIDTMSDEEAEERAREIAEQLGWEEDYYFISAATGKN
VSPLCRDIMDFIIANPREAETQQVAPEEVKFKWEDYHQERLAEHQFDDDEDWDDDWSEEDDEGIEFIYKP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=322, Percent_Identity=40.3726708074534, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI111955139, Length=316, Percent_Identity=37.9746835443038, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI111955063, Length=153, Percent_Identity=40.5228758169935, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI4758796, Length=229, Percent_Identity=27.0742358078603, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI58761500, Length=128, Percent_Identity=34.375, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789574, Length=389, Percent_Identity=73.2647814910026, Blast_Score=516, Evalue=1e-147,
Organism=Escherichia coli, GI1787454, Length=128, Percent_Identity=33.59375, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508313, Length=299, Percent_Identity=40.8026755852843, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=321, Percent_Identity=31.7757009345794, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17509631, Length=143, Percent_Identity=34.965034965035, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=30.5084745762712, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=175, Percent_Identity=37.1428571428571, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=31.7460317460317, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129375, Length=326, Percent_Identity=39.5705521472393, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24585318, Length=380, Percent_Identity=34.2105263157895, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=33.59375, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=33.59375, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=33.59375, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=33.0708661417323, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 43377; Mature: 43377

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDESLIRIEAGDGGNGCVSFRREKFIPKGGPDGGDGGDGGDVYLQADENLNTLIDYR
CCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
FNKRFAAERGENGRSSDCTGRRGKDIILPVPVGTRAIDNDTKETLGDLTQHGQKMLVAKG
HCCHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECC
GYHGLGNTRFKSSVNRAPRQKTMGTPGEKRDLLLELMLLADVGMLGLPNAGKSTFIRAVS
CCCCCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTLVPSLGVVKVDDSHSFVVADIPGLIEGAADGAGLGIRFLKHLERCRV
HCCCCCCCCCHHHHHCCCCEEEECCCCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHH
LIHLVDIAPIDGSNPADNMAIIESELFQYSEKLSEKPRWLVFNKIDTMSDEEAEERAREI
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHH
AEQLGWEEDYYFISAATGKNVSPLCRDIMDFIIANPREAETQQVAPEEVKFKWEDYHQER
HHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHCCHHHHEECHHHHHHHH
LAEHQFDDDEDWDDDWSEEDDEGIEFIYKP
HHHHCCCCCCCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MKFIDESLIRIEAGDGGNGCVSFRREKFIPKGGPDGGDGGDGGDVYLQADENLNTLIDYR
CCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHH
FNKRFAAERGENGRSSDCTGRRGKDIILPVPVGTRAIDNDTKETLGDLTQHGQKMLVAKG
HCCHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECC
GYHGLGNTRFKSSVNRAPRQKTMGTPGEKRDLLLELMLLADVGMLGLPNAGKSTFIRAVS
CCCCCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTLVPSLGVVKVDDSHSFVVADIPGLIEGAADGAGLGIRFLKHLERCRV
HCCCCCCCCCHHHHHCCCCEEEECCCCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHH
LIHLVDIAPIDGSNPADNMAIIESELFQYSEKLSEKPRWLVFNKIDTMSDEEAEERAREI
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHH
AEQLGWEEDYYFISAATGKNVSPLCRDIMDFIIANPREAETQQVAPEEVKFKWEDYHQER
HHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHCCHHHHEECHHHHHHHH
LAEHQFDDDEDWDDDWSEEDDEGIEFIYKP
HHHHCCCCCCCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA