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The map label for this gene is ndh

Identifier: 16272688

GI number: 16272688

Start: 805980

End: 807314

Strand: Direct

Name: ndh

Synonym: HI0747

Alternate gene names: 16272688

Gene position: 805980-807314 (Clockwise)

Preceding gene: 16272687

Following gene: 30995398

Centisome position: 44.04

GC content: 36.48

Gene sequence:

>1335_bases
ATGAAAAACGTCGTGATCGTTGGTGGGGGTGCTGGCGGTATTGAATTAGCAACATTTTTGGGTAATAAATTAGGTCGTCA
AAAACAAGCTAAAGTAACGCTGGTTGATCGCAATGCCACCCATTTATGGAAACCCTTATTGCATGAAATTGCAACAGGCG
TAATGGATGATGGCGTTGATTCTTTAAGTTATCGTGCGCACGGTAAAAATCATTTTTTCAGTTTTGAGCAAGGTTCAATT
ATACGTATTAATCGCGAGCAAAAATATGTTGAACTTGCACCTGTTTATGGACAAGAGGGCGATATGCTTGTCATTGCTCG
TCGAATTCCTTACGATTATTTAGTGATTGCCATTGGCAGTAAATCTAATGATTTCAACACAAAAGGGGTGGCTGATAATT
GTATTTTTTTAGATAGTTCAAAACAGGCTTTACGTTTTCAACATAAACTGTTGGAATTATTTTTAAAATTTTCAGAAAAC
CGCGCATTAGATGACATTGGCGAAGAAGAATTTAAACAAAAGTTAGTGGATGAAAATAAAGTAAATATTGCTATTGTGGG
AGGTGGAGCAACTGGTGTGGAATTAACCGCAGAACTTTATCATGCCGCTGAAGATTTGTCTTCTTACGGTTATGGTAAAA
TTGATAGTTCTTGCTTACAAGTTACTTTAGTCGAAGCAGGAACACGTTTATTGCCAGCATTACCTGAAAATTTATCTGCT
GCAGTGTTAGATGAATTAAAGGAAATGGGCACCAATGTGCAATTAAACACAATGATTACTGAGGCGCAGCCAAATACACT
TATTACCAAAGATGGCGGGGAGATTAAGGCTGATCTTATTGTTTGGGCAGCAGGGGTTCGCGCCTCAACAGTAACGCAGC
AATTTGATGGATTAGAAATTAATCGTATCAATCAATTAGTGGTTAAAGATACACTTCAAACTACCGTTGATGATAGTATT
TTTGCGATTGGCGATTGTGCTGCATTAATACAATCAAATGGTAAATTGGTTCCGCCAAGAGCGCAAGCTGCACATCAAAT
GGCAAAGGCTTGTGCAAAAAATATTTTTGCATTGTTTGAAAATAAACCACTGAAATCTTTTAAATATAACGATAAAGGTA
CTTTAGTTTCTTTGTCAAATTTTACCGCACTTGGTAGTCTAACCAATAAGTTTGGTAAAAATCCACTTACCGTTCAAGGT
AAATTTGCGCAGTTTGCTTATGTGTCTTTGTATCGAATGCACCAACATGCTTTGCACGGTTGTATTAAAATTGGTTTGAT
TATTCTCGTTGATAAATTGAATCGTTATTTAAAACCAAGATTAAAATTGCATTGA

Upstream 100 bases:

>100_bases
GTGCGGTTATTTTTATGAAAGTTTTCCGCCCTGTTTCGTTGTTATGTTATCATTACATTAATGTAACATTTTTAACAATT
TAAACTTTTAGGAGAGCTTT

Downstream 100 bases:

>100_bases
TTAAGTATAATTTTTCGTTAAATGCGATCTAAATCATTTATATAAAAGAAAGGGCATCAATGATGCCCTCAGTATTGTTT
TATGAAGAAAGATCTTCGGA

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKNVVIVGGGAGGIELATFLGNKLGRQKQAKVTLVDRNATHLWKPLLHEIATGVMDDGVDSLSYRAHGKNHFFSFEQGSI
IRINREQKYVELAPVYGQEGDMLVIARRIPYDYLVIAIGSKSNDFNTKGVADNCIFLDSSKQALRFQHKLLELFLKFSEN
RALDDIGEEEFKQKLVDENKVNIAIVGGGATGVELTAELYHAAEDLSSYGYGKIDSSCLQVTLVEAGTRLLPALPENLSA
AVLDELKEMGTNVQLNTMITEAQPNTLITKDGGEIKADLIVWAAGVRASTVTQQFDGLEINRINQLVVKDTLQTTVDDSI
FAIGDCAALIQSNGKLVPPRAQAAHQMAKACAKNIFALFENKPLKSFKYNDKGTLVSLSNFTALGSLTNKFGKNPLTVQG
KFAQFAYVSLYRMHQHALHGCIKIGLIILVDKLNRYLKPRLKLH

Sequences:

>Translated_444_residues
MKNVVIVGGGAGGIELATFLGNKLGRQKQAKVTLVDRNATHLWKPLLHEIATGVMDDGVDSLSYRAHGKNHFFSFEQGSI
IRINREQKYVELAPVYGQEGDMLVIARRIPYDYLVIAIGSKSNDFNTKGVADNCIFLDSSKQALRFQHKLLELFLKFSEN
RALDDIGEEEFKQKLVDENKVNIAIVGGGATGVELTAELYHAAEDLSSYGYGKIDSSCLQVTLVEAGTRLLPALPENLSA
AVLDELKEMGTNVQLNTMITEAQPNTLITKDGGEIKADLIVWAAGVRASTVTQQFDGLEINRINQLVVKDTLQTTVDDSI
FAIGDCAALIQSNGKLVPPRAQAAHQMAKACAKNIFALFENKPLKSFKYNDKGTLVSLSNFTALGSLTNKFGKNPLTVQG
KFAQFAYVSLYRMHQHALHGCIKIGLIILVDKLNRYLKPRLKLH
>Mature_444_residues
MKNVVIVGGGAGGIELATFLGNKLGRQKQAKVTLVDRNATHLWKPLLHEIATGVMDDGVDSLSYRAHGKNHFFSFEQGSI
IRINREQKYVELAPVYGQEGDMLVIARRIPYDYLVIAIGSKSNDFNTKGVADNCIFLDSSKQALRFQHKLLELFLKFSEN
RALDDIGEEEFKQKLVDENKVNIAIVGGGATGVELTAELYHAAEDLSSYGYGKIDSSCLQVTLVEAGTRLLPALPENLSA
AVLDELKEMGTNVQLNTMITEAQPNTLITKDGGEIKADLIVWAAGVRASTVTQQFDGLEINRINQLVVKDTLQTTVDDSI
FAIGDCAALIQSNGKLVPPRAQAAHQMAKACAKNIFALFENKPLKSFKYNDKGTLVSLSNFTALGSLTNKFGKNPLTVQG
KFAQFAYVSLYRMHQHALHGCIKIGLIILVDKLNRYLKPRLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1787352, Length=444, Percent_Identity=56.0810810810811, Blast_Score=492, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6323515, Length=428, Percent_Identity=27.803738317757, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320118, Length=365, Percent_Identity=28.2191780821918, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323794, Length=453, Percent_Identity=26.2693156732892, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DHNA_HAEIN (P44856)

Other databases:

- EMBL:   L42023
- PIR:   C64090
- RefSeq:   NP_438906.1
- ProteinModelPortal:   P44856
- GeneID:   949772
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0747
- TIGR:   HI_0747
- HOGENOM:   HBG668030
- OMA:   HRFRTEM
- ProtClustDB:   CLSK892382
- BioCyc:   HINF71421:HI_0747-MONOMER
- BRENDA:   1.6.99.3
- GO:   GO:0006810
- InterPro:   IPR013027
- InterPro:   IPR001327
- PRINTS:   PR00368

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.6.99.3

Molecular weight: Translated: 48779; Mature: 48779

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVVIVGGGAGGIELATFLGNKLGRQKQAKVTLVDRNATHLWKPLLHEIATGVMDDGVD
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCC
SLSYRAHGKNHFFSFEQGSIIRINREQKYVELAPVYGQEGDMLVIARRIPYDYLVIAIGS
CCEEEECCCCCEEEECCCCEEEEECCCCEEEEEECCCCCCCEEEEEECCCCEEEEEEECC
KSNDFNTKGVADNCIFLDSSKQALRFQHKLLELFLKFSENRALDDIGEEEFKQKLVDENK
CCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHCCCCC
VNIAIVGGGATGVELTAELYHAAEDLSSYGYGKIDSSCLQVTLVEAGTRLLPALPENLSA
EEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEECCCCHHCCCCCCCCHH
AVLDELKEMGTNVQLNTMITEAQPNTLITKDGGEIKADLIVWAAGVRASTVTQQFDGLEI
HHHHHHHHHCCCEEEEEEEECCCCCEEEECCCCCEEEEEEEEECCCCHHHHHHHHCCCCH
NRINQLVVKDTLQTTVDDSIFAIGDCAALIQSNGKLVPPRAQAAHQMAKACAKNIFALFE
HHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
NKPLKSFKYNDKGTLVSLSNFTALGSLTNKFGKNPLTVQGKFAQFAYVSLYRMHQHALHG
CCCCCCCEECCCCCEEEECCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHH
CIKIGLIILVDKLNRYLKPRLKLH
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKNVVIVGGGAGGIELATFLGNKLGRQKQAKVTLVDRNATHLWKPLLHEIATGVMDDGVD
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCC
SLSYRAHGKNHFFSFEQGSIIRINREQKYVELAPVYGQEGDMLVIARRIPYDYLVIAIGS
CCEEEECCCCCEEEECCCCEEEEECCCCEEEEEECCCCCCCEEEEEECCCCEEEEEEECC
KSNDFNTKGVADNCIFLDSSKQALRFQHKLLELFLKFSENRALDDIGEEEFKQKLVDENK
CCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHCCCCC
VNIAIVGGGATGVELTAELYHAAEDLSSYGYGKIDSSCLQVTLVEAGTRLLPALPENLSA
EEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEECCCCHHCCCCCCCCHH
AVLDELKEMGTNVQLNTMITEAQPNTLITKDGGEIKADLIVWAAGVRASTVTQQFDGLEI
HHHHHHHHHCCCEEEEEEEECCCCCEEEECCCCCEEEEEEEEECCCCHHHHHHHHCCCCH
NRINQLVVKDTLQTTVDDSIFAIGDCAALIQSNGKLVPPRAQAAHQMAKACAKNIFALFE
HHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
NKPLKSFKYNDKGTLVSLSNFTALGSLTNKFGKNPLTVQGKFAQFAYVSLYRMHQHALHG
CCCCCCCEECCCCCEEEECCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHH
CIKIGLIILVDKLNRYLKPRLKLH
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800