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The map label for this gene is lpxH [H]

Identifier: 16272676

GI number: 16272676

Start: 789055

End: 789768

Strand: Direct

Name: lpxH [H]

Synonym: HI0735

Alternate gene names: 16272676

Gene position: 789055-789768 (Clockwise)

Preceding gene: 16272670

Following gene: 16272678

Centisome position: 43.11

GC content: 36.13

Gene sequence:

>714_bases
ATGAAACATAGCTATTTTATTTCTGATTTGCATTTAAGCGAAACTCAGCCAGAATTGACCGCACTTTTTGTCGATTTTAT
GCAGAATCTTGCCCCTCAGGCTGAACGGCTTTACATTTTGGGTGATCTTTTTGATTTTTGGATTGGTGATGATGAGCAAT
CTGCATTGATTCAACAAGTGAAAGATTTAATTAAATTTGTAAGTGATCAAGGTGTGCAATGTTATTTTCAGCACGGCAAC
CGTGATTTCTTGATTGGTGAACGTTTTTCAAAAGAAACGGGAGCTCAGCTTTTACCTGATTATCAATTGATTACACTTTA
TGATAAAAAAATCTTACTTTGTCATGGCGATACGCTTTGTATTGATGATGAGGCTTACCAACAATTTCGCCGTAGAGTGC
ATCAAAAATGGCTGCAACGTTTGTTTTTGTGCTTGCCATTAAAAGTGCGGGTGATAATTGCGGAGAAAATTCGAGCAAAG
AGTAATCAAGATAAACAAGCGAAATCTCAGGAAATTATGGATGTAAACCAAGCATTCACGGCAGAAAAAGTACAAGAATT
TGGTGTAAATTTATTAATTCACGGACACACACACCGTGAGGCGATTCATCAACAAGAAGAATTTACCCGAATTGTATTAG
GGGATTGGCGAAAAAATTACGCATCAATTTTAAAAATGGATGAAAGCGGAGAATTTGGTTTTATTAAAGATTAG

Upstream 100 bases:

>100_bases
AAGTAGTTTTAACATAAGGATGTCCTATATAAAATTTCCTTGAAGTATAACAAATTCGATCTCAATATGTGCTAATCTAA
ACAAAAATCGTGGAATTTTT

Downstream 100 bases:

>100_bases
AATTGCGGTAAAGCAAAAACTCGTTATTTTACTTAATGATACTAGAATAATACTTATCCATAAAATCATACCTAAAAGCT
GGTGGATAAGCCCAACTTTT

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSALIQQVKDLIKFVSDQGVQCYFQHGN
RDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCIDDEAYQQFRRRVHQKWLQRLFLCLPLKVRVIIAEKIRAK
SNQDKQAKSQEIMDVNQAFTAEKVQEFGVNLLIHGHTHREAIHQQEEFTRIVLGDWRKNYASILKMDESGEFGFIKD

Sequences:

>Translated_237_residues
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSALIQQVKDLIKFVSDQGVQCYFQHGN
RDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCIDDEAYQQFRRRVHQKWLQRLFLCLPLKVRVIIAEKIRAK
SNQDKQAKSQEIMDVNQAFTAEKVQEFGVNLLIHGHTHREAIHQQEEFTRIVLGDWRKNYASILKMDESGEFGFIKD
>Mature_237_residues
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSALIQQVKDLIKFVSDQGVQCYFQHGN
RDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCIDDEAYQQFRRRVHQKWLQRLFLCLPLKVRVIIAEKIRAK
SNQDKQAKSQEIMDVNQAFTAEKVQEFGVNLLIHGHTHREAIHQQEEFTRIVLGDWRKNYASILKMDESGEFGFIKD

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=217, Percent_Identity=50.6912442396313, Blast_Score=234, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 27786; Mature: 27786

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSALIQQV
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHCCCCHHHHHHHHH
KDLIKFVSDQGVQCYFQHGNRDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLC
HHHHHHHHCCCCEEEEECCCEEEEECCHHCHHCCHHHCCCCEEEEEECCEEEEEECCEEE
IDDEAYQQFRRRVHQKWLQRLFLCLPLKVRVIIAEKIRAKSNQDKQAKSQEIMDVNQAFT
ECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AEKVQEFGVNLLIHGHTHREAIHQQEEFTRIVLGDWRKNYASILKMDESGEFGFIKD
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC
>Mature Secondary Structure
MKHSYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSALIQQV
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHCCCCHHHHHHHHH
KDLIKFVSDQGVQCYFQHGNRDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLC
HHHHHHHHCCCCEEEEECCCEEEEECCHHCHHCCHHHCCCCEEEEEECCEEEEEECCEEE
IDDEAYQQFRRRVHQKWLQRLFLCLPLKVRVIIAEKIRAKSNQDKQAKSQEIMDVNQAFT
ECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AEKVQEFGVNLLIHGHTHREAIHQQEEFTRIVLGDWRKNYASILKMDESGEFGFIKD
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA