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The map label for this gene is devB [H]

Identifier: 16272500

GI number: 16272500

Start: 576109

End: 576600

Strand: Reverse

Name: devB [H]

Synonym: HI0556

Alternate gene names: 16272500

Gene position: 576600-576109 (Counterclockwise)

Preceding gene: 16272501

Following gene: 16272499

Centisome position: 31.51

GC content: 41.06

Gene sequence:

>492_bases
ATGGTTCCGCCATCTGATCCTGAAAGTAACTATGGCGAAGTGCAAAAACTTTTATTCGATCATATTCAAATTCCAGCAGA
AAACATCCATCGAATTCGTGGCGAAAATGAACCGCACTTTGAGCTAAAACGCTTCGAAGAAGAATTAAGTGCGGTCATTC
CAAACGGTGTTTTTGATTGGATTATTTTAGGCATGGGGATTGATGGTCATACCGCCTCTCTCTTCCCACATCAAACTAAT
TTTGATGATGAAAACCTAGCTGTCATTGCTAAGCATCCTGAAAGTGGTCAAATTCGCATTTCTAAAACAGCCAAACTCAT
TGAACAAGCCAAACGCATTACCTATTTGGTAACGGGTGAAAGCAAAGCGGATATTTTAAAAGAAATCCAAACGACTCCTG
CAGAAAATCTGCCTTACCCTGCTGCCAAAATTAAAGCAAAAAATGGGGTGACGGAGTGGTACTTAGACAAAGCAGCGGTA
AGGCTGCTCTAA

Upstream 100 bases:

>100_bases
TGGTTCGACGCCTAAGTTATTATTTAAAACCCTAGCCAAATCACCTTATGCGGAACAAATTAACTGGAAAAATCTGCATT
TTTGGTGGGGTGATGATCGT

Downstream 100 bases:

>100_bases
TGGAAATTTTAGCCTATATTTTAACTGCACTTGTCACCCTTGAACATTTCTACATTCTCTATTTAGAAATGTTCACCATT
GAAAGCAAAAGTGGTGTTCG

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MVPPSDPESNYGEVQKLLFDHIQIPAENIHRIRGENEPHFELKRFEEELSAVIPNGVFDWIILGMGIDGHTASLFPHQTN
FDDENLAVIAKHPESGQIRISKTAKLIEQAKRITYLVTGESKADILKEIQTTPAENLPYPAAKIKAKNGVTEWYLDKAAV
RLL

Sequences:

>Translated_163_residues
MVPPSDPESNYGEVQKLLFDHIQIPAENIHRIRGENEPHFELKRFEEELSAVIPNGVFDWIILGMGIDGHTASLFPHQTN
FDDENLAVIAKHPESGQIRISKTAKLIEQAKRITYLVTGESKADILKEIQTTPAENLPYPAAKIKAKNGVTEWYLDKAAV
RLL
>Mature_163_residues
MVPPSDPESNYGEVQKLLFDHIQIPAENIHRIRGENEPHFELKRFEEELSAVIPNGVFDWIILGMGIDGHTASLFPHQTN
FDDENLAVIAKHPESGQIRISKTAKLIEQAKRITYLVTGESKADILKEIQTTPAENLPYPAAKIKAKNGVTEWYLDKAAV
RLL

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=167, Percent_Identity=36.5269461077844, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI6912586, Length=168, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324362, Length=177, Percent_Identity=31.0734463276836, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321687, Length=179, Percent_Identity=29.0502793296089, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319918, Length=179, Percent_Identity=31.2849162011173, Blast_Score=68, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6321957, Length=170, Percent_Identity=28.2352941176471, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900
- InterPro:   IPR006148 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 18338; Mature: 18338

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPPSDPESNYGEVQKLLFDHIQIPAENIHRIRGENEPHFELKRFEEELSAVIPNGVFDW
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHH
IILGMGIDGHTASLFPHQTNFDDENLAVIAKHPESGQIRISKTAKLIEQAKRITYLVTGE
HHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHEEEEEECC
SKADILKEIQTTPAENLPYPAAKIKAKNGVTEWYLDKAAVRLL
CHHHHHHHHHCCCCCCCCCCHHHEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVPPSDPESNYGEVQKLLFDHIQIPAENIHRIRGENEPHFELKRFEEELSAVIPNGVFDW
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHH
IILGMGIDGHTASLFPHQTNFDDENLAVIAKHPESGQIRISKTAKLIEQAKRITYLVTGE
HHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHEEEEEECC
SKADILKEIQTTPAENLPYPAAKIKAKNGVTEWYLDKAAVRLL
CHHHHHHHHHCCCCCCCCCCHHHEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]