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The map label for this gene is apaH [H]

Identifier: 16272495

GI number: 16272495

Start: 571717

End: 572544

Strand: Direct

Name: apaH [H]

Synonym: HI0551

Alternate gene names: 16272495

Gene position: 571717-572544 (Clockwise)

Preceding gene: 16272493

Following gene: 16272496

Centisome position: 31.24

GC content: 40.22

Gene sequence:

>828_bases
ATGGCAACCTATTTCGTCGGTGATTTGCAAGGCTGTTATGATGAATTACAGCTTTTATTAGAACGTGTAGATTTCAATCC
TACGCAAGATAAACTTTATCTTGTGGGGGATCTTGTGGCGCGTGGGGATAAATCACTTGAATGTCTTCGTTTTGTAAAAT
CACTTGGTAATGCAGCGCAAACCGTACTAGGCAATCACGATTTACATTTAATTGCGACCGCACTGGACATTAAAAAAGTG
AAACCGCGTGATCGTGTTGATGCCATTTTTAATGCGCCCGATTTTGATGAGCTGATTCATTGGTTACGTCATCAGCCATT
ACTTGTGCATAATGAAAAGTTAAACTTCCTGATGTCACACGCAGGCATTTCCCCAGATTGGGATTTGAAAACTGCGAAAT
CTTGTGCGGCTGAAGTTGAACAAATTTTACAGCACGGCGATTTTCATTATCTTATTGAAAATATGTATTCTGAACAGCCT
GATCGCTGGTCGCCAGATTTACAGGGCTTAGCACGTCATCGCTACATTATTAATGCTTTCACTCGAATGCGTTTTTGCTA
TTTGGATCATCGCTTTGATTTTGCCTGTAAATCCCCTTTAAAAGATGCGCCAGCGGAGCTCACACCTTGGTTTAATTTAG
ATAATCCACTTTATAAACAAATTCCCATTGTCTTTGGGCATTGGGCAAGTTTAGTGGATGAGCCTACTCCAAAAGGTATT
TATGCCTTAGATACTGGTTGTGTGTGGAATAATCGAATGACTATGTTGCGTTGGGAAGACAAGCAGTTCTTCACTCAAAG
TGCGGTCAAAAATTACAGTGATTTTTAA

Upstream 100 bases:

>100_bases
ATAACTAAATTTTTCGCATTCTACTATACAAAAAGAATAAATCAACAATAAAAGTCTGTGTTAAAATTTTCAAAATTTAT
TTATAAAAGAGCGGTCAAAA

Downstream 100 bases:

>100_bases
GGAAACGCTATGCTCTCGCTCACTGCTGAATCTTGCGAACTGTTCAACATTCCTTTCTACCAATTCGCCCAAATGAAAAA
ATTCTGCCCAGAAGATATTC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MATYFVGDLQGCYDELQLLLERVDFNPTQDKLYLVGDLVARGDKSLECLRFVKSLGNAAQTVLGNHDLHLIATALDIKKV
KPRDRVDAIFNAPDFDELIHWLRHQPLLVHNEKLNFLMSHAGISPDWDLKTAKSCAAEVEQILQHGDFHYLIENMYSEQP
DRWSPDLQGLARHRYIINAFTRMRFCYLDHRFDFACKSPLKDAPAELTPWFNLDNPLYKQIPIVFGHWASLVDEPTPKGI
YALDTGCVWNNRMTMLRWEDKQFFTQSAVKNYSDF

Sequences:

>Translated_275_residues
MATYFVGDLQGCYDELQLLLERVDFNPTQDKLYLVGDLVARGDKSLECLRFVKSLGNAAQTVLGNHDLHLIATALDIKKV
KPRDRVDAIFNAPDFDELIHWLRHQPLLVHNEKLNFLMSHAGISPDWDLKTAKSCAAEVEQILQHGDFHYLIENMYSEQP
DRWSPDLQGLARHRYIINAFTRMRFCYLDHRFDFACKSPLKDAPAELTPWFNLDNPLYKQIPIVFGHWASLVDEPTPKGI
YALDTGCVWNNRMTMLRWEDKQFFTQSAVKNYSDF
>Mature_274_residues
ATYFVGDLQGCYDELQLLLERVDFNPTQDKLYLVGDLVARGDKSLECLRFVKSLGNAAQTVLGNHDLHLIATALDIKKVK
PRDRVDAIFNAPDFDELIHWLRHQPLLVHNEKLNFLMSHAGISPDWDLKTAKSCAAEVEQILQHGDFHYLIENMYSEQPD
RWSPDLQGLARHRYIINAFTRMRFCYLDHRFDFACKSPLKDAPAELTPWFNLDNPLYKQIPIVFGHWASLVDEPTPKGIY
ALDTGCVWNNRMTMLRWEDKQFFTQSAVKNYSDF

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=271, Percent_Identity=52.7675276752767, Blast_Score=318, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31909; Mature: 31778

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYFVGDLQGCYDELQLLLERVDFNPTQDKLYLVGDLVARGDKSLECLRFVKSLGNAAQ
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHCCCCHHHHHHHHHHHHHHHH
TVLGNHDLHLIATALDIKKVKPRDRVDAIFNAPDFDELIHWLRHQPLLVHNEKLNFLMSH
HHHCCCCCEEEEEHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCEEEECHHHHHHHHH
AGISPDWDLKTAKSCAAEVEQILQHGDFHYLIENMYSEQPDRWSPDLQGLARHRYIINAF
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TRMRFCYLDHRFDFACKSPLKDAPAELTPWFNLDNPLYKQIPIVFGHWASLVDEPTPKGI
HHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
YALDTGCVWNNRMTMLRWEDKQFFTQSAVKNYSDF
EEEECCEEECCCEEEEEECHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATYFVGDLQGCYDELQLLLERVDFNPTQDKLYLVGDLVARGDKSLECLRFVKSLGNAAQ
CEEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHCCCCHHHHHHHHHHHHHHHH
TVLGNHDLHLIATALDIKKVKPRDRVDAIFNAPDFDELIHWLRHQPLLVHNEKLNFLMSH
HHHCCCCCEEEEEHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCEEEECHHHHHHHHH
AGISPDWDLKTAKSCAAEVEQILQHGDFHYLIENMYSEQPDRWSPDLQGLARHRYIINAF
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TRMRFCYLDHRFDFACKSPLKDAPAELTPWFNLDNPLYKQIPIVFGHWASLVDEPTPKGI
HHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
YALDTGCVWNNRMTMLRWEDKQFFTQSAVKNYSDF
EEEECCEEECCCEEEEEECHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA