Click here to switch to the map view.

The map label for this gene is rbsR

Identifier: 16272450

GI number: 16272450

Start: 522876

End: 523874

Strand: Direct

Name: rbsR

Synonym: HI0506

Alternate gene names: 16272450

Gene position: 522876-523874 (Clockwise)

Preceding gene: 16272449

Following gene: 16272451

Centisome position: 28.57

GC content: 40.94

Gene sequence:

>999_bases
ATGGCGACAATGAAAGATATTGCACGACTGGCGCAAGTTTCGACTTCCACAGTTTCACATGTCATTAATGGATCGCGTTT
TGTTAGCGATGAAATTCGTGAGAAAGTGATGCGTATTGTCGCTGAACTGAATTACACCCCCTCAGCTGTTGCACGAAGCC
TTAAGGTGCGCGAAACCAAAACTATCGGACTACTTGTCACCGCAACAAATAATCCCTTCTTTGCGGAAGTGATGGCTGGC
GTGGAGCAATATTGTCAGAAAAATCAATATAATCTTATTATTGCTACAACGGGTGGAGATGCCAAACGCCTACAACAAAA
TCTGCAAACTCTAATGCACAAACAAGTGGATGGTTTGCTTTTGATGTGTGGTGATAGCCGTTTTCAGGCTGATATAGAGT
TAGCCATTTCGCTGCCACTGGTTGTGATGGACTGGTGGTTTACTGAGTTAAATGCAGATAAAATACTCGAAAATTCAGCA
CTTGGTGGCTATTTGGCGACAAAAGCATTAATTGATGCAGGACATCGTAAAATTGGCATTATTACGGGAAATCTCAAAAA
ATCTGTCGCACAAAATCGTTTGCAAGGTTATAAAAATGCGCTCTCGGAAGCAAAAATTGCGTTAAATCCTCATTGGATTG
TCGAAAGTCATTTTGACTTTGAAGGCGGTGTACTTGGCATACAATCTTTACTTACTCAATCTTCACGTCCAACAGCAGTT
TTTTGTTGTAGTGACACCATTGCTGTCGGTGCATACCAAGCTATTCAGCAACAAGGCTTACGTATTCCGCAAGATCTTTC
AATTATGGGTTATGATGACATTGAATTGGCTCGTTATCTCTCACCTCCTCTCTCCACCATTTGCCAACCGAAAGCTGAAC
TTGGCAAACTCGCTGTTGAAACACTATTGCAACGAATTAAAAATCCTAATGAAAATTACCGCACTTTGGTGTTAGAACCG
ACTTGTGTGTTAAGAGAGTCTATTTACAGTTTAAAATAA

Upstream 100 bases:

>100_bases
TGTGACGAAAAAAGGGGCTCAATCCTCTATTCCAACGCGGCAAGAAACTTTGGAATTTCTTGAACACGCTTAAAGTGCGG
TGAATTTTTAGGGTGTTTTT

Downstream 100 bases:

>100_bases
AATTAGAATAACTCGATTTCTCTATTGCTATTTTCAAAAAAACTGCTATTTTCTTGCGGTTTTTTTGTTTATTTAACCCA
CTGTTTAATTTAGGAATAAA

Product: RBS repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MATMKDIARLAQVSTSTVSHVINGSRFVSDEIREKVMRIVAELNYTPSAVARSLKVRETKTIGLLVTATNNPFFAEVMAG
VEQYCQKNQYNLIIATTGGDAKRLQQNLQTLMHKQVDGLLLMCGDSRFQADIELAISLPLVVMDWWFTELNADKILENSA
LGGYLATKALIDAGHRKIGIITGNLKKSVAQNRLQGYKNALSEAKIALNPHWIVESHFDFEGGVLGIQSLLTQSSRPTAV
FCCSDTIAVGAYQAIQQQGLRIPQDLSIMGYDDIELARYLSPPLSTICQPKAELGKLAVETLLQRIKNPNENYRTLVLEP
TCVLRESIYSLK

Sequences:

>Translated_332_residues
MATMKDIARLAQVSTSTVSHVINGSRFVSDEIREKVMRIVAELNYTPSAVARSLKVRETKTIGLLVTATNNPFFAEVMAG
VEQYCQKNQYNLIIATTGGDAKRLQQNLQTLMHKQVDGLLLMCGDSRFQADIELAISLPLVVMDWWFTELNADKILENSA
LGGYLATKALIDAGHRKIGIITGNLKKSVAQNRLQGYKNALSEAKIALNPHWIVESHFDFEGGVLGIQSLLTQSSRPTAV
FCCSDTIAVGAYQAIQQQGLRIPQDLSIMGYDDIELARYLSPPLSTICQPKAELGKLAVETLLQRIKNPNENYRTLVLEP
TCVLRESIYSLK
>Mature_331_residues
ATMKDIARLAQVSTSTVSHVINGSRFVSDEIREKVMRIVAELNYTPSAVARSLKVRETKTIGLLVTATNNPFFAEVMAGV
EQYCQKNQYNLIIATTGGDAKRLQQNLQTLMHKQVDGLLLMCGDSRFQADIELAISLPLVVMDWWFTELNADKILENSAL
GGYLATKALIDAGHRKIGIITGNLKKSVAQNRLQGYKNALSEAKIALNPHWIVESHFDFEGGVLGIQSLLTQSSRPTAVF
CCSDTIAVGAYQAIQQQGLRIPQDLSIMGYDDIELARYLSPPLSTICQPKAELGKLAVETLLQRIKNPNENYRTLVLEPT
CVLRESIYSLK

Specific function: Transcriptional repressor for the ribose rbsDACBK operon

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=49.3939393939394, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=43.8066465256798, Blast_Score=291, Evalue=3e-80,
Organism=Escherichia coli, GI1790369, Length=331, Percent_Identity=34.441087613293, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1788474, Length=333, Percent_Identity=33.033033033033, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789202, Length=332, Percent_Identity=33.1325301204819, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789068, Length=301, Percent_Identity=30.5647840531561, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1787580, Length=312, Percent_Identity=31.4102564102564, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790715, Length=321, Percent_Identity=26.791277258567, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI48994940, Length=309, Percent_Identity=27.831715210356, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1786540, Length=307, Percent_Identity=29.3159609120521, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1787906, Length=327, Percent_Identity=24.1590214067278, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1786268, Length=323, Percent_Identity=25.6965944272446, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789456, Length=317, Percent_Identity=25.5520504731861, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790192, Length=270, Percent_Identity=28.8888888888889, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RBSR_HAEIN (P44329)

Other databases:

- EMBL:   L42023
- PIR:   C64073
- RefSeq:   NP_438664.1
- ProteinModelPortal:   P44329
- SMR:   P44329
- GeneID:   949576
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0506
- NMPDR:   fig|71421.1.peg.477
- TIGR:   HI_0506
- HOGENOM:   HBG753640
- OMA:   HAVERYC
- ProtClustDB:   CLSK869986
- BioCyc:   HINF71421:HI_0506-MONOMER
- GO:   GO:0005622
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761
- PRINTS:   PR00036
- SMART:   SM00354

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1; SSF47413 Lambda_like_DNA

EC number: NA

Molecular weight: Translated: 36716; Mature: 36585

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00356 HTH_LACI_1; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATMKDIARLAQVSTSTVSHVINGSRFVSDEIREKVMRIVAELNYTPSAVARSLKVRETK
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEE
TIGLLVTATNNPFFAEVMAGVEQYCQKNQYNLIIATTGGDAKRLQQNLQTLMHKQVDGLL
EEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEE
LMCGDSRFQADIELAISLPLVVMDWWFTELNADKILENSALGGYLATKALIDAGHRKIGI
EEECCCCCCCEEEEEEECCHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEE
ITGNLKKSVAQNRLQGYKNALSEAKIALNPHWIVESHFDFEGGVLGIQSLLTQSSRPTAV
EECHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEECCCCCCCCHHHHHHHHCCCCCCCEE
FCCSDTIAVGAYQAIQQQGLRIPQDLSIMGYDDIELARYLSPPLSTICQPKAELGKLAVE
EEECCHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHCCCCHHHHCCCHHHHHHHHHH
TLLQRIKNPNENYRTLVLEPTCVLRESIYSLK
HHHHHHCCCCCCCEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure 
ATMKDIARLAQVSTSTVSHVINGSRFVSDEIREKVMRIVAELNYTPSAVARSLKVRETK
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEE
TIGLLVTATNNPFFAEVMAGVEQYCQKNQYNLIIATTGGDAKRLQQNLQTLMHKQVDGLL
EEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEE
LMCGDSRFQADIELAISLPLVVMDWWFTELNADKILENSALGGYLATKALIDAGHRKIGI
EEECCCCCCCEEEEEEECCHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHCCCCEEEE
ITGNLKKSVAQNRLQGYKNALSEAKIALNPHWIVESHFDFEGGVLGIQSLLTQSSRPTAV
EECHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEECCCCCCCCHHHHHHHHCCCCCCCEE
FCCSDTIAVGAYQAIQQQGLRIPQDLSIMGYDDIELARYLSPPLSTICQPKAELGKLAVE
EEECCHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHCCCCHHHHCCCHHHHHHHHHH
TLLQRIKNPNENYRTLVLEPTCVLRESIYSLK
HHHHHHCCCCCCCEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800