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The map label for this gene is comF

Identifier: 16272382

GI number: 16272382

Start: 456269

End: 456958

Strand: Reverse

Name: comF

Synonym: HI0434

Alternate gene names: 16272382

Gene position: 456958-456269 (Counterclockwise)

Preceding gene: 16272383

Following gene: 16272381

Centisome position: 24.97

GC content: 38.12

Gene sequence:

>690_bases
ATGATGAATTTTTTTAATTTTCGCTGTATCCACTGTCGTGGCAATCTTCATATCGCAAAAAATGGGTTATGTTCAGGTTG
CCAAAAACAAATTAAATCTTTTCCTTATTGCGGTCATTGTGGTTCGGAATTGCAATATTATGCGCAGCATTGTGGGAATT
GTCTTAAACAAGAACCAAGTTGGGATAAGATGGTCATTATTGGGCATTATATTGAACCTCTTTCGATATTGATTCAGCGT
TTTAAATTTCAAAATCAATTTTGGATTGACCGCACTTTAGCTCGGCTTTTATATCTTGCGGTACGTGATGCTAAACGAAC
GCATCAACTTAAATTGCCAGAGGCAATCATTCCAGTGCCTTTATATCATTTTCGTCAGTGGCGACGGGGTTATAATCAGG
CAGATTTATTATCTCAGCAATTAAGTCGTTGGCTGGATATTCCTAATTTGAACAATATCGTAAAGCGTGTGAAACACACC
TATACTCAACGTGGTTTGAGTGCAAAAGATCGTCGTCAGAATTTAAAAAATGCCTTTTCTCTTGCTGTTTCGAAAAATGA
ATTTCCTTATCGTCGTGTTGCGTTGGTGGATGATGTGATTACTACTGGTTCTACACTCAATGAAATCTCAAAATTGTTGC
GAAAATTAGGTGTGGAGGAGATTCAAGTGTGGGGGCTGGCACGAGCTTAA

Upstream 100 bases:

>100_bases
AACGTGAGCTAGTGATTTTCGTCACGCCACATATTTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGAG
GGTAAAAAATAACTTTTTAA

Downstream 100 bases:

>100_bases
TATAAAGCACTGGAAAAAAAAGCGCGATAAGCGTATTATTCCCGATACTTTCTCTCAAGTATTTAGGACATAATTATGGA
ACAAGCAACCCAGCAAATCG

Product: competence protein F

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MMNFFNFRCIHCRGNLHIAKNGLCSGCQKQIKSFPYCGHCGSELQYYAQHCGNCLKQEPSWDKMVIIGHYIEPLSILIQR
FKFQNQFWIDRTLARLLYLAVRDAKRTHQLKLPEAIIPVPLYHFRQWRRGYNQADLLSQQLSRWLDIPNLNNIVKRVKHT
YTQRGLSAKDRRQNLKNAFSLAVSKNEFPYRRVALVDDVITTGSTLNEISKLLRKLGVEEIQVWGLARA

Sequences:

>Translated_229_residues
MMNFFNFRCIHCRGNLHIAKNGLCSGCQKQIKSFPYCGHCGSELQYYAQHCGNCLKQEPSWDKMVIIGHYIEPLSILIQR
FKFQNQFWIDRTLARLLYLAVRDAKRTHQLKLPEAIIPVPLYHFRQWRRGYNQADLLSQQLSRWLDIPNLNNIVKRVKHT
YTQRGLSAKDRRQNLKNAFSLAVSKNEFPYRRVALVDDVITTGSTLNEISKLLRKLGVEEIQVWGLARA
>Mature_229_residues
MMNFFNFRCIHCRGNLHIAKNGLCSGCQKQIKSFPYCGHCGSELQYYAQHCGNCLKQEPSWDKMVIIGHYIEPLSILIQR
FKFQNQFWIDRTLARLLYLAVRDAKRTHQLKLPEAIIPVPLYHFRQWRRGYNQADLLSQQLSRWLDIPNLNNIVKRVKHT
YTQRGLSAKDRRQNLKNAFSLAVSKNEFPYRRVALVDDVITTGSTLNEISKLLRKLGVEEIQVWGLARA

Specific function: Involved in transformation (competence for DNA uptake)

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family

Homologues:

Organism=Escherichia coli, GI87082263, Length=224, Percent_Identity=43.3035714285714, Blast_Score=163, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COMF_HAEIN (P31773)

Other databases:

- EMBL:   M62809
- EMBL:   M59751
- EMBL:   L42023
- PIR:   JH0435
- RefSeq:   NP_438595.1
- ProteinModelPortal:   P31773
- SMR:   P31773
- GeneID:   950316
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0434
- NMPDR:   fig|71421.1.peg.408
- TIGR:   HI_0434
- HOGENOM:   HBG695777
- OMA:   LHWTRLL
- ProtClustDB:   CLSK870528
- BioCyc:   HINF71421:HI_0434-MONOMER
- InterPro:   IPR005222
- InterPro:   IPR000836
- TIGRFAMs:   TIGR00201

Pfam domain/function: PF00156 Pribosyltran

EC number: NA

Molecular weight: Translated: 26792; Mature: 26792

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNFFNFRCIHCRGNLHIAKNGLCSGCQKQIKSFPYCGHCGSELQYYAQHCGNCLKQEPS
CCCCCCEEEEEEECCEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
WDKMVIIGHYIEPLSILIQRFKFQNQFWIDRTLARLLYLAVRDAKRTHQLKLPEAIIPVP
CCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
LYHFRQWRRGYNQADLLSQQLSRWLDIPNLNNIVKRVKHTYTQRGLSAKDRRQNLKNAFS
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LAVSKNEFPYRRVALVDDVITTGSTLNEISKLLRKLGVEEIQVWGLARA
HHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCC
>Mature Secondary Structure
MMNFFNFRCIHCRGNLHIAKNGLCSGCQKQIKSFPYCGHCGSELQYYAQHCGNCLKQEPS
CCCCCCEEEEEEECCEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
WDKMVIIGHYIEPLSILIQRFKFQNQFWIDRTLARLLYLAVRDAKRTHQLKLPEAIIPVP
CCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
LYHFRQWRRGYNQADLLSQQLSRWLDIPNLNNIVKRVKHTYTQRGLSAKDRRQNLKNAFS
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LAVSKNEFPYRRVALVDDVITTGSTLNEISKLLRKLGVEEIQVWGLARA
HHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800